Atlas of the Developing Mouse Brain

Atlas of the

Developing Mouse Brain at E17.5, P0, and P6

This page intentionally left blank

Atlas of the

Developing Mouse Brain at E17.5, P0, and P6

George Paxinos Prince of Wales Medical Research Institute The University of New South Wales Sydney, Australia

Glenda Halliday Prince of Wales Medical Research Institute The University of New South Wales Sydney, Australia

Charles Watson Division of Health Sciences Curtin University of Technology Perth, Australia

Yuri Koutcherov Prince of Wales Medical Research Institute The University of New South Wales Sydney, Australia

HongQin Wang Prince of Wales Medical Research Institute The University of New South Wales Sydney, Australia

A MSTERDAM • B OSTON • H EIDELBERG • L ONDON • N EW Y ORK PARIS • S AN D IEGO • S AN F RANCISCO • S INGAPORE • S YDNEY Academic Press is an imprint of Elsevier

• •

O XFORD T OKYO

Academic Press is an imprint of Elsevier 84 Theobald’s Road, London WC1X 8RR, UK Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA First edition 2007 Copyright © 2007 Elsevier Inc. All rights reserved. Cover design by Lewis Tsalis Book design by Lewis Tsalis CD-ROM design by Paul Halasz No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: [email protected]. Alternatively you can submit your request online by visiting the Elsevier web site at http://elsevier.com/locate/permissions, and selecting Obtaining permission to use Elsevier material. Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. ISBN–13: 978-0-12-547622-5 ISBN–10: 0-12-547622-1 CD-ROM ISBN–13: 978-0-12373719-9 CD-ROM ISBN–10: 0-12-373719-2 British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress For information on all Academic Press publications visit our web site at books.elsevier.com Printed and bound in China 07 08 09 10

11

10

9

8

7

6

5

4

3

2

1

We dedicate this book to Paul Halasz, and to Mark, Nelli and George, and ChengShan

This page intentionally left blank

Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IX Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IX Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IX Nomenclature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . X Histology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . X Preparation of photographs and drawings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XI The basis of delineations of structures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XI References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XII Index of structures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XIII Index of abbreviations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XVIII Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XXV

This page intentionally left blank

Preface

Introduction

The period from just before birth to a week after birth is one in which enormous changes occur in the developing brain. Many researchers now use newborn or late prenatal mice in their studies of gene expression on the brain. We have made an atlas which presents the main anatomical features at three ages from E17.5 to P6 which we hope will meet the needs of researchers in this area.

This book is an atlas of brains of late fetal and newborn mice. The ages of E17.5, P0, and P6 were selected to serve the needs of researchers interested in the effects of gene manipulation and other early interventions on late maturing brain anatomy, as well as those with other interests in the development of the brain. Most areas in the P6 and P0 atlases are presented in nearly the same level of detail as our atlas of the adult brain of this species (Paxinos and Franklin, 2003).

We welcome feedback, both positive and negative, on our publication. We have no doubt that many researchers with expertise in specific areas will have local knowledge more sophisticated than our own. We will be delighted to include their contributions in future editions.

Acknowledgements

In delineating structures, we have been informed by our experience in mapping the brains of adults of a variety of mammalian species (e.g. Paxinos and Watson, 2007), our previous work on the developing rat nervous system (Paxinos, et al., 1994), and the work of other authors. The atlas sections were taken at relatively close intervals, and the intervening sections stained with a variety of neuronal markers.

We thank Lewis Tsalis and John Car for speed, accuracy and brilliance in the construction of the diagrams, Lewis Tsalis for the cover design and layout of the book, Julia Tsalis for accurately labelling the diagrams, and Paul Halasz for expert construction of the CD-ROM. Work on rhombomeres reported herein was supported by an Australian Research Council grant and comparative and developmental work on the hypothalamus by a National Health and Medical Research Council grant. We also acknowledge support from the Ronald Geoffrey Arnold Foundation, the Rebecca Cooper Foundation, the Ramaciotti Foundation, and a grant by Elsevier Academic Press for the construction of the atlas. We thank Eleftherios Ferekidis for comments on the peripheral auditory apparatus.

The primary source of information for our delineation was the set of cresyl violet stained sections depicted in the atlas plates. These plates are photographs of 30 µm sections taken at 120 µm intervals (every fourth section was taken for an atlas plate). In many cases, the cresyl violet stain alone gives clear boundaries of nuclear structures, but in the E17.5 day brain there was little evident differentiation in areas such as the thalamus, and other stains proved more useful. Among the other markers we used, the most valuable was calbindin, which shows some nuclei with outstanding contrast. Calretinin was, as always, useful for identifying olfactory structures in the forebrain, but it also stained some structures in caudal parts of the brain. Tyrosine hydroxylase identified only the catecholamine cells bodies, with little terminal staining present especially at the earlier ages.

We thank our editor Dr Johannes Menzel of Elsevier for his support of this project. His judgment, scientific knowledge, and great interpersonal skills have ensured that this work has come to a pleasing conclusion.

We have, as far as possible, drawn in boundaries around the structures we have identified. Where there was insufficient evidence to draw a boundary, we have placed the abbreviation in what we believe to be the centre of the structure identified. The boundaries of cell groups are indicated by dashed lines, and the boundaries of fiber tracts are indicated by continuous lines. The ventricular cavities are indicated by blue shading. We have in some instances, identified structures according to the neuromere from which they develop by the use of a prefix in italics (e.g. mRt represents the mesencephalic part of the reticular formation and p1PAG is the prosomere 1 part of the periaqueductal gray). For a comprehensive atlas of the boundaries of neuromeric domains, we recommend the study of the atlas of the chick brain (Puelles et al., 2007). We believe that in the future the identification of neuromeric origins of cell groups in the mammalian brain will contribute significantly to the understanding of the organization of the developing brain. The representation of structures identified in the P0 and P6 brains can be readily related to those in the adult mouse brain, but the conformation of the E17.5 brain makes such comparisons more difficult. One problem is that the brain is sharply flexed at the caudal end of the mesencephalon (cephalic flexure) and flexed again in the middle of the hindbrain (pontine flexure). Because we used the same plane of section for the whole brain, the hindbrain is sectioned in a way that is difficult at first to interpret. However, there are many outstanding landmarks in this region, and those who use the atlas will find that the anatomy can be mapped with reference to these landmarks. As noted above, almost all of the structures that are represented in the adult brain can be found in the P6 and P0 brain, but the relative sizes of nuclei are often strikingly different from the adult. An example is the relatively large size of the zona incerta. In the E17.5 brain, many fiber bundles are either not present (such as the corpus callosum) or small and hard to identify. The cerebellum in the E17.5 brain is no more than a small bud at the lateral edge of the 4th ventricle. We were unable to accurately parcellate many of the components of

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

IX

the basal telencephalon in the E17.5 brain. In the E17.5 brain, only a few cortical areas are sufficiently differentiated to enable their identification with certainty. In this brain we were able to identify the piriform cortex, amygdalar cortical components, insular cortex, cingulate cortex, retrosplenial cortex, and some components of the subiculum. We have identified a number of structures that lie outside of the brain in the sections of the E17.5 and P0 animals. While we focused on neural structures, such as the eye, inner ear, and peripheral nerves, a number of musculoskeletal structures have also been identified to orient the reader.

Nomenclature In this atlas, the names of brain structures and their abbreviations are based on the system first developed by Paxinos and Watson (1982) and since then used in many other major brain atlases (the mouse brain (Paxinos and Franklin, 2002), the rhesus monkey brain (Paxinos et al., 2000), the human brain (Mai et al., 2004, Paxinos and Huang, 1995), the developing rat brain (Paxinos et al., 1994; Foster, 1998), the hamster brain (Morin and Wood, 2001) and the chick brain (Puelles et al., 2007). Our abbreviations have been constructed on the basis of the following principles: 1. The abbreviations represent the order of words as spoken in English (e.g. DLG = dorsal lateral geniculate nucleus) rather than the order in which they appear in older latinised terms. 2. The approach used in the abbreviations of the names of elements in the periodic table was followed: the capital letter representing the first letter of a word in a nucleus is followed, where necessary, by a lower case letter most characteristic of that word (not necessarily the second letter; e.g. Mg = magnesium; Rt = reticular). 3. All nuclei and other cell groupings (such as cortical areas) begin with a capital letter, except some cranial nerve nuclei which begin with a number followed by capital N (e.g. 12N represents the nucleus of the hypoglossal nerve). All fiber bundles begin with lower case letters except some cranial nerves which begin with a number followed by lower case n (for ‘nerve’, as in 6n = abducens nerve). Thus, there is no necessity for a letter to be used to point out that a structure is a nucleus. Similarly, there is no need for the letter “t” to be used to denote a fiber tract. 4. Compound names of nuclei have a capital letter for each part (e.g. LPGi = lateral paragigantocellular nucleus). 5. If a word occurs in the names of a number of structures, it is almost always given the same abbreviation (e.g. Rt = reticular thalamic nucleus; RtTg = reticulotegmental nucleus of the pons). Exceptions to this rule are made for well-established abbreviations such as VTA. 6. Abbreviations of brain regions are omitted where the identity of the region in question is clear from its position (CM = central median thalamic nucleus; not CMTh).

8. The names of anatomical entities outside the brain are based on those used in the atlas of the developing rat nervous system (Paxinos et al., 1994). However, the abbreviations for these structures were harmonized as far as possible with the abbreviations used by Mai et al (2004). It is our aim to assist scientists to navigate seamlessly between the brains of humans and experimental animals without frivolously introducing different terms or different abbreviations for homologous structures in different animals. This principle can also be applied to the mapping of the avian brain, and we have used the same terms and abbreviations for structures in the chick brain (Puelles et al., 2007) as in mammalian brains (mouse – Paxinos and Franklin, 2003; rat – Paxinos and Watson, 2007; monkey – Paxinos et al., 2000; human – Mai et al., 2004; Paxinos and Huang, 1995).

Histology For staging of embryos, see Paxinos et al. (1994). Following perfusion of dams at 17.5 day of pregnancy, heads of mice were obtained and sectioned in a plane roughly approximating in the forebrain to the coronal plane. We did not determine the sex of the specimens before the brain was sectioned. However, the characteristic morphology of the medial preoptic nucleus in the P6 specimen, strongly suggests that the specimen was male. The sections were cut in a plane approximately at right angles to the superior surface of the calvarium. Because of brain flexion, the plane resembled more the horizontal plane in the region of the rhombencephalon. For Postnatal Day 0 and Day 6, the neonates were killed by decapitation and the heads postfixed in 4% paraformaldehyde for 3-7 days. For all ages, sections were cut at 30 mm thickness, and every fourth section was taken for cresyl violet staining. These cresyl violet stained sections were used for the plates pictured in this atlas.

Cresyl Violet Staining Slides were immersed for 5 min in each of the following: xylene, xylene, 100% alcohol, 100% alcohol, 95% alcohol, and 70% alcohol. They were dipped in distilled water and stained in 0.5% cresyl violet for 15–30 min. They were differentiated in water for 3–5 min and then dehydrated through 70% alcohol, 95% alcohol, and 100% alcohol. They were then put in xylene and coverslipped. To make 500 ml of 0.5% cresyl violet of about pH 3.9, mix 2.5 g of cresylecht violet (Chroma Gesellschaft, Postfach 11 10, D-73257, Kongen, Germany, Fax number: 49-7024-82660), 300 ml of water, 30 ml of 1.0 M sodium acetate (13.6 g of granular sodium acetate in 92 ml of water), and 170 ml of 1.0 M acetic acid (29 ml of glacial acetic acid added to 471 ml of water). Mix this solution for at least 7 days on a magnetic stirrer, then filter. A detailed protocol of the staining procedures for the various neuronal markers used in this work may be obtained from our website: www.powmri.edu.au/staff/paxinos.htm.

7. Arabic numerals are used instead of Roman numerals in identifying cranial nerves and their nuclei, layers of the cortex, and layers of the spinal cord. While the spoken meaning is the same, the detection threshold is lower for Roman numerals. The use of Arabic numerals ensures that ambiguity is reduced. For example, VIII could signal ‘8’ or visual area 3. In addition, the Arabic numerals are easier to position in small spaces available on diagrams (8 is smaller than VIII).

X

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

Preparation of photographs and drawings

The basis of delineations of structures

Photography

The identification of structures is based principally on our previous work on the adult rat and mouse brains and the developing rat nervous system (Paxinos et al., (1994); Paxinos and Watson (2005); Paxinos and Franklin (2003)). We made extensive use of the two chemoarchitectonic atlases of the rat brain (Chemoarchitectonic Atlas of the Rat Forebrain (Paxinos et al., 1999) and Chemoarchitectonic Atlas of the Rat Brainstem (Paxinos et al., 1999b)).

The photographs of stained brain sections were taken with a Nikon Multiphot macrophotographic apparatus using 4”x5” Kodak Plus X film. High contrast filters were used to print the photographs of cresyl violet sections, whereas lower contrast filters were used to print the photographs of intervening sections stained with neuronal markers.

Drawings Drawings, which later formed the basis of the figures, were made by tracing the photographs of sections. The drawings were then digitized using Adobe Illustrator. Fiber tracts in the drawings are outlined by solid lines, and nuclei and cell groups are outlined by broken lines. In general, each abbreviation is placed in the center of the structure to which it relates; where this is not possible, the abbreviation is placed alongside the structure and a leader line is used. The outlines of the ventricles and aqueduct are filled in with solid color. The Figure number appears in the top right corner of each drawing. Under the Figure number is the stage of development and the identity of the section in that particular series. For example, under the heading Figure 52 will appear the line “P0 #11”, which means the eleventh section in the P0 series. Under, the section identity is a number indicating the distance from the most rostral section in that series. In the case of P0 #11, the number is 0.12 mm.

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

We were assisted by the description of brain regions and systems by referring to specific chapters in a comprehensive text on the rat nervous system (Paxinos, 2004). We refer readers to the following sources for further information on specific areas. •

Olfactory system – Shipley et al. (2004)

•

Basal ganglia – Heimer et al. (1995) and Gerfen (2004)

•

Septum, hypothalamus and neurosecretory nuclei Simerly (2004), Risold (2004) and Oldfield and McKinley (2004)

•

Amygdala and bed nucleus of stria terminalis – de Olmos et al. (2004)

•

Hippocampal region – Witter and Amaral (2004)

•

Thalamus – Groenewegen and Witter (2004)

•

Cerebral cortex – Palomero-Gallagher and Zilles (2004)

•

Raphe nuclei – Harding et al. (2004) and Buttner-Ennever et al. (1988)

•

Locus coeruleus and brainstem catecholamine cell groups – Aston-Jones (2004)

•

Brainstem nuclei associated with taste, respiratory, cardiovascular and other autonomic functions – Saper (2004)

•

Periaqueductal gray – Keay and Bandler (2004)

•

Oromotor nuclei – Travers (2004)

•

Precerebellar nuclei – Ruigrok (2004)

•

Cerebellum – (Voogd, 2004)

•

Somatosensory system – Tracey (2004)

•

Visual system – Sefton et al. (2004)

•

Auditory system – Malmierca and Merchan (2004).

XI

References

Mai, JK, Assheuer, J, and Paxinos, G (2004). Atlas of the Human Brain. Elsevier Elsevier Academic Press, San Diego.

Armstrong, WE (2004). Hypothalamic supraoptic and paraventricular nuclei. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 369-388.

Malmierca, MS and Merchan, MA (2004). Auditory system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 996-1081.

Aston-Jones, G (2004). Locus coeruleus, A5 and A7 noradrenergic cell groups. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 259-294.

Morin, LP and Wood, RI (2001) A Stereotaxic Atlas of the Golden Hamster Brain Academic Press, San Diego.

Berman, AL (1968). The Brainstem of the Cat: A Cytoarchitectonic Atlas with Stereotaxic Coordinates. University of Wisconsin Press, Madison. Carrive, P, and Paxinos, G (1994). The supraoculomotor cap: A region revealed by NADPH diaphorase histochemistry. NeuroReport 5, 2257–2260. De Olmos, JS, Beltramino, CA and Alheid, G (2004). Amygdala and extended amygdala of the rat: a cytoarchitectonical, fibroarchitectonical, and chemoarchitectonical survey. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 510-601. Faye-Lund, H, and Osen, KK (1985). Anatomy of the inferior colliculus in rat. Anat. Embryol. 171, 1–20. Foster G (1998). Chemical Neuroanatomy of the Prenatal Rat Brain. A Developmental Atlas. Oxford University Press. New York. 416 pp. Gerfen, CR (2004). Basal ganglia. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 458-509. Groenewegen, HJ and Witter, MP (2004). Thalamus. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 408-457. Harding, A, Paxinos, G, and Halliday, G (2004). The serotonin and tachykinin systems. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 1203-1256. Heimer, L, Zahm, DS, and Alheid, GF (1995). Basal ganglia. In G. Paxinos (Ed), The Rat Nervous System, 2nd ed. Academic Press, San Diego. Hökfelt, T, Martensson, R, Bjorklund, A, Kleinau, S, and Goldstein, M (1984). Distributional maps of tyrosine-hydroxylase-immunoreactive neurons in the rat brain. In A. Bjorklund and T. Hökfelt (Eds), Handbook of Chemical Neuroanatomy, Vol. 2, Part 1. Elsevier, Amsterdam. Holstege, G (2004). Central nervous system control of micturition. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 321-331. Insausti, R, Herrero, MT, and Witter, MP (1997). Entorhinal cortex of the rat: cytoarchitectonic subdivisions and the origin and distribution of cortical efferents. Hippocampus 7: 146: 183. Jacobowitz DM and Abbott LC (1998). Chemoarchitectonic Atlas of the Developing Mouse Brain. CRC Press. New York. Kanjhan, R, Lipski, J, Kruszewska, B, and Rong, W (1995). A comparative study of presympathetic and Bötzinger neurons in the rostral ventrolateral medulla (RVLM) of the rat. Brain Res. 699, 19–32.

Neafsey, EJ, Bold, EL, Haas, G, Hurley-Gius, KM, Quirk, G, Sievert, CF, and Terreberry, RR (1986). The organization of the rat motor cortex: A microstimulation mapping study. Brain Res. Rev. 11, 77–96. Oldfield, BJ and McKinley, MJ (2004). Circumventricular organs. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 389-407. Palomero-Gallagher, N and Zilles, K (2004). Isocortex. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 728-760. Paxinos, G (Ed) (2004). The Rat Nervous System, 3rd ed., Elsevier Academic Press, San Diego. Paxinos, G, and Huang, X-F (1995). Atlas of the Human Brainstem. Academic Press, San Diego. Paxinos, G, and Watson, C (1982). The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney. Paxinos, G, and Watson, C (1986). The Rat Brain in Stereotaxic Coordinates, 2nd ed. Academic Press, San Diego. Paxinos, G and Watson C (1997). The Rat Brain in Stereotaxic Coordinates, Compact 3rd ed. CD-Rom. Academic Press, San Diego. Paxinos, G, and Watson, C (2007). The Rat Brain in Stereotaxic Coordinates, 6th ed. Elsevier Academic Press, San Diego. Paxinos, G, Kus, L, Ashwell, K, and Watson, C (1999a). Chemoarchitecture of the Rat Forebrain. Academic Press, San Diego. Paxinos, G, Carrive, P, Wang, H, and Wang P-Y (1999b). Chemoarchitecture of the Rat Brainstem. Academic Press, San Diego. Paxinos, G, Ashwell, KW, and Tork, I (1994). Atlas of the Developing Rat Nervous System, 2nd ed, Academic Press, San Diego. Paxinos, G, Huang, X-F, and Toga AW (2000). The Rhesus Monkey Brain in Stereotaxic Coordinates. Academic Press, San Diego. Paxinos, G and Franklin, K (2003). The Mouse Brain in Stereotaxic Coordinates. 3rd ed. Elsevier Academic Press, San Diego. Puelles, L, Martinez-de-la-Torre, M, Martinez, S, Watson, C, and Paxinos, G (2007). The Chick Brain in Stereotaxic Coordinates. Elsevier Academic Press, San Diego. Risold, PY (2004). The septal region. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 602-636.

Kaufman MH (1992). The atlas of mouse development. Academic Press – Harcourt Brace Jovanovich. San Diego.

Ruigrok, TJH (2004). Precerebellar nuclei and red nucleus. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 167-204.

Lundy, RF Jr and Norgren, R (2004). Gustatory system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 890-921.

Saper, CB (2004). Central autonomic system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 761-794.

XII

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

Sefton, AJ, Dreher, B and Harvey, A (2004). Visual system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 1082-1164. Scremin, OU (2004). Cerebral vascular system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 1165-1202. Shipley, MT, Ennis, M and Puche, A (2004). Olfactory system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 922-963. Simerly, RB (2004). Anatomical substrates of hypothalamic integration. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 336-368. Tracey, D (2004). Ascending and descending pathways in the spinal cord. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 149-164. Tracey, D (2004). Somatosensory system. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 795-814. Travers, JB (2004). Oromotor nuclei. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 295-320. Voogd, J (2004). Cerebellum. In G. Paxinos (Ed), The Rat Nervous System, 3rd ed. Elsevier Academic Press, San Diego, pp 205-243.

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

XIII

List of Structures

anterior olfactory nucleus, medial part AOM anterior olfactory nucleus, posterior part AOP anterior olfactory nucleus, ventral part AOV

Names of the structures are listed in alphabetical order. Each name is followed by abbreviation of the structure.

anterior olfactory nucleus, ventroposterior part AOVP anterior perifornical nucleus anterior pretectal nucleus

1st cerebellar lobule (lingula) 2nd and 3rd cerebellar lobules

APT

2nd cerebellar lobule

2Cb

anterior semicircular canal ASCC

3rd cerebellar lobule

3Cb

anterior spinal artery asp

3rd ventricle

anterior tegmental nucleus ATg

3V

4th and 5th cerebellar lobules 4th cerebellar lobule 4th ventricle

anterior thalamic region

4/5Cb

4Cb

4V

ATh

anterodorsal thalamic nucleus

AD

anteromedial thalamic nucleus

AM

5Cb

anteromedial thalamic nucleus, ventral part AMV

6th cerebellar lobule

6Cb

anterovent thalamic nucleus, dorsomedial part

7th cerebellar lobule

7Cb

anteroventral periventricular nucleus

8th cerebellar lobule

8Cb

anteroventral thalamic nucleus

9th cerebellar lobule

9Cb

anteroventral thalamic nucleus, ventrolateral part AVVL

10Cb

A

cuneate nucleus, rotundus part CuR

AVDM

AVPe

Botzinger complex Bo

dens of the axis bic

brachium of the superior colliculus bsc

dorsal 3rd ventricle D3V

C

dorsal cochlear nucleus DC

C1

C1 adrenaline cells and A1 noradrenaline cells

C1/A1

apex of cochlea Apex aqueduct

C2 adrenaline cells

dorsal cochlear nucleus, deep core

DCDp

dorsal cochlear nucleus, fusiform layer

DCFu

dorsal cochlear nucleus, molecular layer DCMo dorsal cortex of the inferior colliculus

C2

DCIC

dorsal corticospinal tract dcs

arcuate hypothalamic nucleus, lateral part ArcL

carotid plexus

caudal linear nucleus of the raphe

A11dopamine cells A11

arcuate hypothalamic nucleus, lateroposterior part ArcLP

A13 dopamine cells A13

arcuate hypothalamic nucleus, medial part ArcM

caudate putamen, neuroepithelial zone CPune

A14 dopamine cells A14

arcuate hypothalamic nucleus, medial posterior part ArcMP

caudomedial entothinal cortex CEnt

A4 noradrenaline cells A4 A5 noradrenaline cells A5

area postrema

A7 noradrenaline cells A7

artery a

caudoventrolateral reticular nucleus and C1 cells CVL/C1

abducens nucleus

AP

DAx DG

developing cortex, layer 1 Cx1

carotid canal

A1/C1

deep white layer of the superior colliculus DpWh

descending palatine artery dpal

arcuate hypothalamic nucleus, dorsal part ArcD

A1 noradrenaline cells/C1 adrenaline cells

deep cerebral white matter dcw

dentate gyrus

arcuate hypothalamic nucleus Arc

A1 noradrenaline cells A1

decussation of the superior cerebellar peduncle xscp

deep gray layer of the superior colliculus DpG

carotid body CtdB

a 7Gn

D

bed nucleus of the stria terminalis, medial division, ventral part STMV

C1 cells and caudoventrolateral reticular nucleus C1/CVL

Aq

cuneiform nucleus CnF

decussation of the trapezoid body tzx

C1 adrenaline cells

AV

cuneate nucleus Cu

bed nucleus of the stria terminalis, medial division, posteromedial part STMPM

brachium of the inferior colliculus

5th cerebellar lobule

10th cerebellar lobule (nodule)

bed nucleus of the stria terminalis, medial division, posterior part STMP

bed nucleus of the stria terminalis, medial division, posterolateral part STMPL

anterior pretectal nucleus, ventral part APTV

2/3Cb

cuneate fasciculus cu

bed nucleus of the stria terminalis, medial division, posterointermediate part STMPI

APF

anterior pretectal nucleus, dorsal part APTD

1Cb

bed nucleus of the stria terminalis, medial division, anteromedial part STMAM

dorsal endopiriform nucleus

Ctd

DEn

dorsal fornix df

cpx

dorsal hippocampal commissure dhc

CLi

dorsal horn of spinal cord DH

caudate putamen (striatum) CPu

caudoventrolateral reticular nucleus

dorsal hypothalamic area DA dorsal intermediate entorhinal cortex

DIEnt

dorsal lateral geniculate nucleus DLG

CVL

dorsal lateral olfactory tract dlo dorsal motor nucleus of vagus 10N

arytenoid cartilage Ary

cavernous sinus cav

dorsal nucleus of the lateral lemniscus DLL

abducens nucleus, retractor bulbi part 6RB

ascending fibers of the facial nerve asc7

cell bridges of the ventral striatum CB

dorsal paragigantocellular nucleus DPGi

accessory nerve nucleus

atlantoaxial joint

central amygdaloid nucleus Ce

6N 11N

AtAx

accessory neurosecretory nuclei ANS

atlantooccipital joint

accessory olfactory bulb AOB

atlas Atlas

dorsal part of claustrum DCl

central amygdaloid nucleus, capsular part

AtOc

CeC

central amygdaloid nucleus, lateral division

accumbens nucleus Acb

auditory tube Aud

central amygdaloid nucleus, medial division

accumbens nucleus neuroepithelium Acbne

auditory tube cartilage AudC

central canal CC

accumbens nucleus, core AcbC

axis (C2 vertebra) Axis

central cervical nucleus of the spinal cord

accumbens nucleus, shell

azygous anterior cerebral artery

AcbSh

CeL

dorsal periolivary region

CeM

dorsal raphe nucleus

DPO

DR

dorsal raphe nucleus, caudal part CeCv

DRC

dorsal raphe nucleus, dorsal part DRD dorsal raphe nucleus, lateral part DRL

central gray CG

azac

dorsal peduncular cortex DP

agranular insular cortex, dorsal part AID

central gray, alpha part CGA

dorsal raphe nucleus, ventral part DRV

agranular insular cortex, posterior part AIP

central gray, beta part

dorsal raphe, interfascicular part DRI

agranular insular cortex, ventral part AIV alar ligament of dens

Alar

AOrb

alisphenoid bone

ASph

basal nucleus, core

ambiguus nucleus, loose part AmbL ambiguus nucleus, subcompact part AmbSC Amg

amygdalohippocampal area, anterolateral part AHiAL amygdalohippocampal area, posterolateral AHiPL amygdalohippocampal area, posteromedial part AHiPM

amygdalopiriform transition area

APir

basolateral amygdaloid nucleus

BLA

basolateral amygdaloid nucleus, posterior part

BLP

basolateral amygdaloid nucleus, ventral part BLV BM

acer

anterior chamber of the eye ac

aca

anterior commissure, intrabulbar part aci anterior commissure, posterior part acp anterior cortical amygdaloid nucleus

ACo

anterior hypothalamic area AH anterior hypothalamic area, anterior part AHA anterior hypothalamic area, central part AHC anterior hypothalamic area, posterior part AHP anterior lobe of the pituitary APit anterior olfactory nucleus

bed nucleus of the stria terminalis, intermediate division STI bed nucleus of the stria terminalis, intraamygdaloid division STIA

AntCh

anterior commissure, anterior part

BAC

bed nucleus of the stria terminalis, dorsal part STD

AA

anterior belly of the digastric muscle ADig anterior cerebral artery

bed nucleus of stria terminalis, fusiform part Fu

bed nucleus of the stria terminalis ST

ansoparamedian fissure apmf anterior amygdaloid area

basomedial amygdaloid nucleus, posterior part BMP

bed nucleus of the anterior commissure

angular thalamic nucleus AngT

AO

anterior olfactory nucleus, dorsal part AOD anterior olfactory nucleus, external part AOE anterior olfactory nucleus, lateral part AOL

dorsal spinocerebellar tract and olivocerebellar tract dsc/oc

CIC

CL

dorsal subiculum DS

cbx

dorsal tegmental decussation dtgx dorsal tegmental nucleus DTg dorsal tegmental nucleus, central part

Cx

cerebral peduncle

BL

basolateral amygdaloid nucleus, anterior part

basomedial amygdaloid nucleus

cerebellar commissure

cerebral cortex

bed nucleus of the accessory olfactory tract BAOT

amygdalostriatal transition area ASt

XIV

BSph

centrolateral thalamic nucleus

cp

chorda tympani nerve

dorsal tenia tecta DTT dorsal transition zone

cty

dorsolateral entorhinal cortex

dorsolateral periaqueductal gray

cingulate cortex, area 2 Cg2 cg Cl

clavicle

DTM

DLEnt

dorsolateral orbital cortex DLO

cingulate cortex, area 1 Cg1

claustrum

DTr

dorsal tuberomammillary nucleus

chp

cingulate cortex Cg

cingulum

DTgC

dorsal tegmental nucleus, pericentral part DTgP

cervicoauricular muscle CeAu choroid plexus

DR3V

dorsal spinocerebellar tract dsc

cerebellum Cb

basomedial amygdaloid nucleus, anterior part BMA

af

amygdaloid intramedullary gray IMG

anterior commissure

basisphenoid bone

dorsal root ganglion DRGn

CGO

cerebellar white matter cbw

basilar artery bas BOcc

dorsal recess of third ventricle

central gray, nucleus O

central nucleus of the inferior colliculus

BTel

basioccipital bone

central gray, gamma part CGG central medial thalamic nucleus CM

base of stapes BStap

Amb

amygdaloid fissure

B

BCo

basal telencephalon, neuroepithelial zone BTelne

ambiguus nucleus, compact part AmbC

amygdala

Bar

basal telencephalon

alveus of the hippocampus alv ambiguus nucleus

Barrington’s nucleus

basal nucleus (Meynert)

alar nucleus Al alar orbital bone

B

CGB

DLPAG

dorsomedial hypothalamic nucleus

DM

dorsomedial hypothalamic nucleus, compact part DMC

Clav

cochlear (spiral) ganglion

dorsomedial hypothalamic nucleus, dorsal part

CGn

DMD

dorsomedial hypothalamic nucleus, ventral part DMV

cochlear duct CD cochlear root of the vestibulocochlear nerve 8cn commissural nucleus of the inferior colliculus

Com

commissural stria terminalis cst commissure of the superior colliculus csc

dorsomedial periaqueductal gray

DMPAG

dorsomedial spinal trigeminal nucleus dorsomedial tegmental area dysgranular insular cortex

DMSp5

DMTg DI

bed nucleus of the stria terminalis, lateral division, dorsal part STLD

common crus of the semicircular canals CCrus condylar process of mandible Cond

E

bed nucleus of the stria terminalis, lateral division, intermediate part STLI

copula of the pyramis Cop

ectorhinal cortex

cornea Cornea

Edinger-Westphal nucleus

bed nucleus of the stria terminalis, lateral division, juxtacapsular part STLJ

coronoid process of the mandible Cor

emissary vein

emv

corpus callosum

enamel organ

EnO

bed nucleus of the stria terminalis, lateral division, posterior part STLP

cortex-amygdala transition zone CxA

endolymphatic sac

cortex-amygdala transition zone, layer 1 CxA1

entopeduncular nucleus

bed nucleus of the stria terminalis, lateral division, ventral part STLV

cortex-amygdala transition zone, layer 2 CxA2

entorhinal cortex Ent

cortical plate CxP

entorhinal cortex, neuroepithelial zone Entne

bed nucleus of the stria terminalis, medial division, anterior part STMA

cribriform plate of the ethmoid crus 1 of the ansiform lobule

Crus1

epiglottis

bed nucleus of the stria terminalis, medial division, anterolateral part STMAL

crus 2 of the ansiform lobule

Crus2

epipeduncular nucleus EpP

cc

CrP

Ect EW

ELS EP

ependyma and subependymal layer E EpiG

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

episupraoptic nucleus

ESO

horizontal semicircular canal ampulla HSCCA hyoglossus muscle HyGl

interstitial nucleus of the posterior limb of the anterior commissure IPAC

layer 1 of developing cortex 1Cx

ethmoid bone EthB

layer 2 of cortex

2

ethmoid thalamic nucleus Eth

hyoid bone

interstitial nucleus of the vestibulocochlear nerve I8

layer 3 of cortex

3

exorbital gland

hypoglossal canal

interventricular foramen

layer 4 of cortex

4

ExOrb

external capsule

ec

external carotid artery ectd external cortex of the inferior colliculus external cuneate nucleus

12C

intramedullary thalamic area

hypoglossal nucleus, geniohyoid part 12GH

iris Iris

external plexiform layer of the olfactory bulb EPl eye Eye

I indusium griseum

jugular foramen

ialn

inferior meatus

F cell group of the vestibular complex FVe

inferior oblique capitis muscle

facial motor nucleus, stylohyoid part 7SH

inferior olivary nucleus IO

facial nerve 7n

inferior olive, beta subnucleus

facial nucleus

inferior olive, cap of Kooy of the medial nucleus

IOBe IOK

facial nucleus, dorsomedial subnucleus 7DM

inferior olive, medial nucleus

facial nucleus, lateral subnucleus 7L

inferior olive, principal nucleus

inferior olive, subnucleus C of medial nucleus IOC

fasciola cinereum FC

inferior olive, ventrolateral protrusion IOVL

field CA1 of the hippocampus CA1

inferior ophthalmic artery iopha

field CA2 of the hippocampus CA2

inferior rectus muscle IRec

field CA3 of the hippocampus CA3

inferior salivatory nucleus IS

fields of Forel

infralimbic cortex IL

fimbria of the hippocampus fi

infraorbital artery iorb

flocculus Fl

infraorbital foramen

foramen magnum

FMag

infundibulum

IOrbF

Inf

forceps minor of the corpus callosum fmi

insular cortex Ins

fornix f

interanterodorsal thalamic nucleus

IAD

frontal and parietal bones Fro/Par

interanteromedial thalamic nucleus

IAM

frontal assocn cortex FrA

intercalated amygdaloid nucleus, main part IM

frontal bone Fro

intercalated nuclei of the amygdala

I

frontal cortex, area 3 Fr3

intercalated nucleus of the medulla

In

gelatinous layer of the caudal spinal trigeminal nucleus Ge5 gemini hypothalamic nucleus genioglossus muscle

GeHy

intermediate nucleus of the lateral lemniscus

g7 Gi

gigantocellular reticular nucleus, alpha part

GiA

gigantocellular reticular nucleus, ventral part

GiV

GP

glomerular layer of the olfactory bulb Gl glossopharyngeal and vagus nerves 9/10n glossopharyngeal nerve

9n

glossopharyngeal, vagus, and accessory nerves 9/10/11n gonial process

intermediate white layer of the superior colliculus InWh intermediodorsal thalamic nucleus

IMD

internal arcuate fibers ia internal auditory meatus internal capsule

IAud

internal jugular vein

ijugv

internal medullary lamina iml interpeduncular fossa IPF

gracile fasciculus gr

interpeduncular nucleus

Gr

granular cell layer of the olfactory bulb GrO granular insular cortex GI granular layer of the dentate gyrus

GrDG

granule cell layer of cochlear nuclei GrC granule cell layer of the accessory olfactory bulb GrA granule cell layer of the cerebellum GrCb

lateral amygdaloid nucleus, ventrolateral part

mammillotegmental tract mtg

IP

interpeduncular nucleus, apical subnucleus

IPA

interpeduncular nucleus, caudal subnucleus

IPC

mammillothalamic tract mt

lateral cerebellar nucleus, parvicellular part LatPC

mandible Man

lateral column of the spinal cord lc

marginal zone of the medial geniculate MZMG

lateral entorhinal cortex

masseter muscle MasM

LEnt LHb

masseteric artery

interpeduncular nucleus, dorsomedial subnucleus IPDM interpeduncular nucleus, intermediate subnucleus

IPI

LHbL

masa

masseteric nerve masn

lateral habenular nucleus, medial part LHbM

masseteric vein

lateral hypothalamic area LH

mastoid process of temporal bone Mst

lateral lemniscus ll

matrix region of the medulla Mx LM

maxillary artery

masv

mxa

lateral olfactory tract

lo

maxillary bone (maxilla)

lateral orbital cortex

LO

maxillary vein LPB

MxB

mxv

Meckel’s cartilage Mc

lateral parabrachial nucleus, central part LPBC

medial (fastigial) cerebellar nucleus

lateral parabrachial nucleus, external part LPBE

medial accessory oculomotor nucleus MA3

lateral parabrachial nucleus, internal part LPBI

medial amygdaloid nucleus

lateral parabrachial nucleus, superior part

medial amygdaloid nucleus, ant dorsal

LPBS

Med

Me MeAD

lateral paragigantocellular nucleus LPGi

medial amygdaloid nucleus, anterior part

lateral parietal association cortex LPtA

medial amygdaloid nucleus, anteroventral part MeAV

lateral periaqueductal gray LPAG

medial amygdaloid nucleus, posterodorsal part MePD LP

MeA

medial amygdaloid nucleus, posteroventral part MePV

lateral posterior thalamic nucleus, laterorostral part LPLR

medial cerebellar nucleus, dorsolateral protuberance MedDL

lateral posterior thalamic nucleus, mediorostral part LPMR

medial cerebellar nucleus, lateral part MedL

lateral preoptic area

medial eminence, internal layer MEI

LPO LPtg

medial eminence, external layer MEE medial entorhinal cortex MEnt

LR4V

medial forebrain bundle mfb

lateral rectus capitis muscle LReCa

medial geniculate nucleus

lateral rectus muscle LRec

medial geniculate nucleus, dorsal part MGD

lateral reticular nucleus

medial geniculate nucleus, medial part MGM

LRt

MG

lateral reticular nucleus, parvicellular part LRtPC

medial geniculate nucleus, ventral part MGV

lateral reticular nucleus, subtrigeminal part LRtS5

medial habenular nucleus

lateral septal nucleus

medial lemniscus ml

LS

lateral septal nucleus, dorsal part

interpeduncular nucleus, dorsolateral subnucleus IPDL

LaVL

lateral amygdaloid nucleus, ventromedial part LaVM

lateral recess of the 4th ventricle

ictd

mp

mammillary recess of the 3rd ventricle MRe

lateral pterygoid muscle

ic

internal carotid artery

mammillary peduncle

lateral posterior thalamic nucleus

internal plexiform layer of the olfactory bulb IPl

Gonial

gracile nucleus

ILL

intermediate reticular nucleus IRt

gigantocellular reticular nucleus

globus pallidus

InG

intermediate lobe of the pituitary IPit

genu of the corpus callosum gcc genu of the facial nerve

intermediate cortical layer ICx intermediate gray layer of the superior colliculus

GeGl

geniohyoid muscle

intergeniculate leaf IGL intermediate endopiriform nucleus IEn

Gem

LAcbSh

lateral parabrachial nucleus

interfascicular nucleus IF

Mall

mammillary body MB

lateral amygdaloid nucleus, dorsolateral part LaDL

lateral mammillary nucleus

intercrural fissure icf

G

lateral accumbens shell

Lat

lateral habenular nucleus, lateral part

inner plexiform layer of the retina InPl

magnocellular nucleus of the lateral hypothalamus MCLH

malleus

lateral (dentate) cerebellar nucleus

lateral habenular nucleus

forceps major of the corpus callosum fmj

M

magnocellular preoptic nucleus MCPO

lat amygdaloid nucleus La

fasciculus retroflexus fr

LgCa

magnocellular nucleus of the posterior commissure MCPC

LarPh

larynx Lar

inferior olive, subnucleus A of medial nucleus IOA inferior olive, subnucleus B of medial nucleus IOB

FF

longus capitis muscle

L laryngopharynx

IOPr

LC

longitudinal fasciculus of the pons lfp KF

lambdoid septal zone Ld

IOM

loculated brown fat Fat longissimus capitis muscle LgsCa

lacunosum moleculare layer of the hippocampus LMol

inferior olive, dorsal nucleus IOD

lithoid nucleus Lth locus coeruleus

Kˆlliker-Fuse nucleus

inferior olive, dorsomedial cell group IODM

7VM

lingual nerve lgn

JugF

K

IObCa

Li

lingual artery lga

I9Gn

InfM

facial nucleus, dorsolateral subnucleus 7DL

7VI

levator palpebrae superioris muscle LPS

juxtaparaventricular part of lateral hypothalamus JPLH

IC

F

7DI

levator palati muscle LPal ICjM

J

IG

inferior alveolar nerve

inferior ganglion of the glossopharyngeal nerve

7N

LTer

Lens

linear nucleus of the medulla

incus Inc

inferior colliculus

facial nucleus, ventromedial subnucleus

lemina terminalis lens

islands of Calleja, major island

inferior cerebellar peduncle (restiform body) icp

Eyelid

facial nucleus, ventral intermediate subnucleus

IMA

islands of Calleja ICj

external medullary lamina eml

facial nucleus, dorsal intermediate subnucleus

IVF

hypoglossal nucleus 12N ECIC

ECu

external granular layer of developing cerebellum EGL

eyelid

Hyoid

LSD

MHb

medial lemniscus decussation mlx

lateral septal nucleus, intermediate part LSI

medial longitudinal fasciculus mlf

lateral septal nucleus, ventral part LSV

medial mammillary nucleus, lateral part ML

lateral stripe of the striatum LSS

medial mammillary nucleus, medial part MM

lateral superior olive LSO

medial mammillary nucleus, median part MnM

lateral terminal nucleus of the accessory optic tract LT

medial orbital cortex MO medial parabrachial nucleus

interpeduncular nucleus, lateral subnucleus

IPL

lateral ventricle LV

H

interpeduncular nucleus, rostral subnucleus

IPR

lateral vestibular nucleus

habenular commissure hbc

interposed cerebellar nucleus Int

lateroanterior hypothalamic nucleus

interposed cerebellar nucleus, anterior part IntA

laterodorsal tegmental nucleus LDTg

interposed cerebellar nucleus, dorsolateral hump IntDL

laterodorsal tegmental nucleus, ventral part laterodorsal thalamic nucleus LD

medial preoptic nucleus

interposed cerebellar nucleus, posterior part IntP

laterodorsal thalamic nucleus, dorsomedial part LDDM

medial preoptic nucleus, central part MPOC

laterodorsal thalamic nucleus, ventrolateral part LDVL

medial preoptic nucleus, medial part MPOM

habenular nuclei

Hb

hamulus of the pterygoid bone handle of malleus

HPtg

HMall

handle of stapes HStap Harderian gland

HardG

hemisphere of cerebellum

Hem

interposed cerebellar nucleus, posterior parvicellular part IntPPC

hippocampal fissure hif

interstitial nucleus of Cajal

InC

hippocampal region Hi

interstitial nucleus of the medulla IB

horizontal semicircular canal HSCC

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

LVe LA

lateroventral periolivary nucleus LVPO layer 1 of cortex

1

MPB

medial parabrachial nucleus external part MPBE medial paralemniscial nucleus MPL medial parietal association cortex LDTgV

MPtA

medial preoptic area MPA MPO

medial preoptic nucleus, lateral part MPOL medial pretectal nucleus MPT medial pterygoid muscle medial rectus muscle

MPtg

MRec

XV

medial septal nucleus MS

occipital sinus occs

parietal cortex, posterior area, rostral part PtPR

primary somatosensory cortex, jaw region

medial superior olive MSO

oculomotor nerve 3n

parietal plate

ParP

medial terminal nucleus of the accessory optic tract MT

oculomotor nucleus

parotid gland

Ptd

primary somatosensory cortex, oral dysgranular zone S1DZO

oculomotor nucleus, parvicellular part 3PC

parvicellular reticular nucleus PCRt

primary somatosensory cortex, shoulder region

medial tuberal nucleus

olfactory nerve layer ON

parvicellular reticular nucleus, alpha part PCRtA

primary somatosensory cortex, trunk region

medial vestibular nucleus MVe

olfactory nerve or its rootlets 1n

peduncular part of lateral hypothalamus PLH

medial vestibular nucleus, magnocellular part MVeMC

olfactory tubercle Tu

pedunculopontine tegmental nucleus PTg

primary somatosensory cortex, upper lip region S1ULp

olfactory tubercle, layer 1 Tu1

periaqueductal gray PAG

primary visual cortex

medial vestibular nucleus, parvicellular part MVePC

olfactory ventricle (olfactory part of lateral ventricle) OV

perifacial zone

primary visual cortex, binocular area V1B

olivary pretectal nucleus OPT

perifornical part of lateral hypothalamus PeFLH

principal mammillary tract

perilemniscal nucleus, ventral part PLV

principal sensory trigeminal nucleus Pr5

peripeduncular nucleus PP

principal sensory trigeminal nucleus, dorsomedial part Pr5DM

MTu

median accessory nucleus of the medulla

MnA

median eminence ME median preoptic nucleus median raphe nucleus

MnPO

olivocochlear bundle

MnR

omohyoid muscle

mediodorsal thalamic nucleus

3N

MD

ocb

OmHy

P7

perifornical nucleus

perirhinal cortex PRh

mediodorsal thalamic nucleus, central part MDC

ophthalmic vein ophv

peritrigeminal zone P5

mediodorsal thalamic nucleus, lateral part MDL

optic chiasm

periventricular hypothalamic nucleus Pe

mediodorsal thalamic nucleus, medial part MDM

optic disc

OpD

pterygopalatine nerve

optic fiber layer of the retina OF

pineal gland Pi

medullary reticular nucleus, dorsal part MdD

optic foramen

pinna of the ear Pinna

medullary reticular nucleus, ventral part MdV

optic nerve 2n

piriform cortex

mesencephalic reticular formation mRt

optic nerve layer of the superior colliculus Op

piriform cortex, layer 1

mesencephalic trigeminal nucleus

optic tract

pleoglial periaqueductal gray PlPAG

opt

Purkinje cell layer of the cerebellum

Pk

pyramidal cell layer of the hippocampus Py

Pir

pyramidal decussation pyx

Pir1

pyramidal tract py

oral cavity Oral

polymorph layer of the dentate gyrus

microcellular tegmental nucleus MiTg

organ of Corti Corti

pontine nuclei Pn

middle cerebellar peduncle mcp

oriens layer of the hippocampus Or

pontine raphe nucleus

middle cerebral artery

otic ganglion

pontine reticular nucleus, caudal part PnC

raphe interpositus nucleus

Otic

Ptg

ptgpal

mesencephalic trigeminal tract me5

mcer

pm

pterygoid process of the sphenoid bone

medioventral periolivary nucleus MVPO

Me5

V1

principal sensory trigeminal nucleus, ventrolateral part Pr5VL

pigment layer of the eye Pig

OptF

PoDG

R PnR

radiatum layer of the hippocampus Rad RIP

middle meatus MidM

oval paracentral thalamic nucleus OPC

pontine reticular nucleus, oral part PnO

raphe magnus nucleus

mitral cell layer of the accessory olfactory bulb MiA

oval window

pontine reticular nucleus, ventral part PnV

raphe obscurus nucleus

posterior belly of the digastric muscle PDig

raphe pallidus nucleus

posterior cerebral artery pcer

Rathke’s pouch

posterior commissure pc

recess of the inferior colliculus

posterior hypothalamic area PHA

rectus capitis posterior major muscle RCPMj

posterior hypothalamic area, dorsal part PHD

red nucleus R

posterior hypothalamic nucleus

red nucleus, magnocellular part RMC

OvalW

mitral cell layer of the olfactory bulb Mi molecular layer of the cerebellum MoCb

P

molecular layer of the dentate gyrus MoDG motor root of the trigeminal nerve motor trigeminal nucleus

palatine bone

m5

palatoglossus muscle PalGl

5N

parabigeminal nucleus

motor trigeminal nucleus, anterior digastric part 5ADi

parabrachial nucleus

motor trigeminal nucleus, tensor tympani part 5TT

PBG PB

parabrachial pigmented nucleus of the VTA PBP paracentral thalamic nucleus PC

mylohyoid muscle MyHy

nasal cavity NasC NSpt

nerve of the pterygoid canal

Nv

ptgcn

neuroepithelial zone of developing cortex

Cxne

neuroepithelium ne

ROb RPa

Rath

posterior intralaminar thalamic nucleus PIL

red nucleus, parvicellular part RPC

posterior limitans thalamic nucleus

Reichert’s cartilage Rc

PLi

reticluostrial nucleus

reticular thalamic nucleus Rt

parafascicular thalamic nucleus PF

posterior semicircular canal PSCC

reticulotegmental nucleus of the pons RtTg

parafloccular cavity

PFlCv

posterior semicircular canal ampulla PSCCA

pfs

posterior superior alveolar artery psa

reticulotegmental nucleus of the pons, lateral part RtTgL

RtSt

paraflocculus PFl

posterior superior fissure

parainterfascicular nucleus of the VTA PIF

posterior thalamic nuclear group Po

reticulotegmental nucleus of the pons, pericentral part RtTgP

paralambdoid septal nucleus

posterior thalamic nuclear group, triangular part PoT

retinal ganglion cell layer of the retina

posterodorsal preoptic nucleus

retroambiguus nucleus

PLd

paramedian lobule PM

psf

PDPO

retrochiasmatic area

paramedian reticular nucleus PMn

posterodorsal tegmental nucleus

retrochiasmatic area, lateral part

nucleus of origin of efferents of the vestibular nerve EVe

paramedian sulcus pms

posteroinferior cerebellar artery pica

nucleus of Roller Ro

parapyramidal nucleus

ns

nucleus of Darkschewitsch

paramedian raphe nucleus Dk

nucleus of the ansa lenticularis

AL

paranigral nucleus of the VTA pararubral nucleus

nucleus of the brachium of the inferior colliculus

BIC

parastrial nucleus

nucleus of the fields of Forel

parasubiculum

nucleus of the horizontal limb of the diagonal band HDB nucleus of the lateral olfactory tract LOT

PaR PS

paratenial thalamic nucleus

paratrochlear nucleus

nucleus of the optic tract OT

Pa5 Pa4

paraventricular hypoth nucleus PCom

paraventricular hypothalamic nucleus, anterior parvicellular part PaAP

nucleus of the solitary tract Sol nucleus of the solitary tract, central part SolCe nucleus of the solitary tract, commissural part SolC nucleus of the solitary tract, dorsomedial part SolDM nucleus of the solitary tract, gelatinous part SolG nucleus of the solitary tract, intermediate part SolIM nucleus of the solitary tract, lateral part SolL nucleus of the solitary tract, medial part SolM nucleus of the solitary tract, rostrolateral part SolRL nucleus of the solitary tract, ventrolateral part SolVL nucleus of the stria medullaris SM nucleus of the trapezoid body Tz nucleus of the vertical limb of the diagonal band

VDB

RSD

retrosplenial granular cortex RSG

Post

retrosplenial granular cortex, a region RSGa

PrLSp

pre-Botzinger complex PrBo

retrosplenial granular cortex, b region RSGb

pre-Edinger-Westphal nucleus PrEW

retrosplenial granular cortex, c region RSGc

precommissural nucleus

retrouniens area RRe

PrC

preculminate fissure pcuf

reuniens thalamic nucleus

precuneiform area

rhabdoid nucleus Rbd

prelimbic cortex

PrCnF

Re

rhinal fissure rf

PrL

root of abducens nerve 6n

paraventricular hypothalamic nucleus, lateral magnocellular part PaLM

preoptic hypothalamus POHy

root of accessory nerve

prepositus nucleus Pr

root of hypoglossal nerve 12n

paraventricular hypothalamic nucleus, medial magnocellular part PaMM

prepyramidal fissure ppf

rostral amygdalopiriform area

prerubral field

paraventricular hypothalamic nucleus, medial parvicellular part PaMP

presphenoid bone

PSph

rostral interstitial nucleus of medial longitudinal fasciculus RI

presphenoid wing

PSphW

rostral linear nucleus of the raphe

paraventricular hypothalamic nucleus, posterior part PaPo

presubiculum PrS prethalamus (prosomere 3) PrTh

rostral ventrolateral reticular nucleus C1/RVL

paraventricular hypothalamic nucleus, ventral part PaV

primary auditory cortex

rostroventrolateral reticular nucleus

PV

PaXi

ParB

parietal cortex Pt

occipital artery occ

parietal cortex, posterior area, caudal part PtPC

occipital bone

parietal cortex, posterior area, dorsal part PtPD

XVI

retrosplenial dysgranular cortex

PoMn

RRF/A8

retrorubral nucleus RR

rhomboid thalamic nucleus

parietal bone

Occ

retrorubral field and A8 dopamine cells PMCo

RPF

RRF

premammillary nucleus, ventral part PMV

paraxiphoid nucleus of thalamus

O

RL

RChL

PMD

paraventricular thalamic nucleus, posterior part PVP

nucleus Z Z

retrolemniscal nucleus retrorubral field

plf

premammillary nucleus, dorsal part

paraventricular thalamic nucleus, anterior part PVA

nucleus Y Y

REth

posterolateral fissure

paraventricular hypothalamic nucleus, dorsal cap PaDC

paraventricular thalamic nucleus

nucleus X X

Pa

retroethmoid nucleus

retroparafascicular nucleus

pre lateral spinal

PT

PLCo

RCh

posterolateral cortical amygdaloid nucleus, layer 1 PLCo1

postsubiculum

paraterete nucleus PTe paratrigeminal nucleus

posterolateral cortical amygdaloid nucleus

posteromedian thalamic nucleus

parasubthalamic nucleus PSTh

nucleus of the lateral olfactory tract, layer 2 LOT2

PDTg

posteromedial cortical amygdaloid nucleus

PaS

nucleus of the lateral olfactory tract, layer 1 LOT1

nucleus of the posterior commissure

PN

PPy

parasolitary nucleus PSol

nucleus of the central acoustic tract CAT F

PMnR

RGn

RAmb

posterodorsal raphe nucleus PDR

nigrostriatal bundle

ReIC

posterior pretectal nucleus PPT

parafloccular sulcus

navicular nucleus of the basal forebrain

PH

RMg

posterior lobe of pituitary PPit

paracommissural nucleus of the posterior commissure PaC

N nasal septum

Pal

S1Sh

S1Tr

primary visual cortex, monocular area V1M

PeF

ophthalmic artery opha och

S1J

PR

11n RAPir

RLi

rostral ventral respiratory group RVRG Au1

rubrospinal tract

primary fissure prf primary motor cortex

Rh

RVL

rs

M1

primary somatosensory cortex

S

S1

primary somatosensory cortex, barrel field S1BF

saccule Sacc

primary somatosensory cortex, dysgranular zone S1DZ

sagulum nucleus Sag salpingopharyngeus muscle

primary somatosensory cortex, forelimb region

S1FL

primary somatosensory cortex, hindlimb region

S1HL

SalPh

scala tympani ScTy scala vestibuli ScVe

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

scaphoid thalamic nucleus

Sc

superficial gray layer of the superior colliculus SuG

scapula Scap

superficial temporal vein stv

second cervical vertebra CV2 secondary auditory cortex, dorsal area AuD

superior cerebellar peduncle (brachium conjunctivum) scp

secondary auditory cortex, ventral area AuV

superior colliculus SC

secondary fissure sf

superior constrictor muscle of the pharynx SCM

secondary motor cortex M2

superior ganglion of the glossopharyngeal nerve S9Gn

secondary somatosensory cortex S2

superior meatus SupM

secondary visual cortex, lateral area V2L

superior medullary velum

secondary visual cortex, mediolateral area V2ML

superior oblique capitis muscle

secondary visual cortex, mediomedial area V2MM

superior oblique muscle

sensory root of the trigeminal nerve

superior olivary nucleus. lateral part SOl

septofimbrial nucleus

s5

septohypothalamic nucleus SHy

superior sagittal sinus sss

septum

superior salivatory nucleus

Spt

SObCa

superior vestibular nucleus

simple lobule Sim

suprachiasmatic nucleus SCh

VG1

ventral hippocampal commissure vhc

SuVe

ventral horn of spinal cord VH ventral intermediate entorhinal cortex VIEnt SChDL

solitary tract sol

suprageniculate thalamic nucleus

SG

ventral linear nucleus of the thalamus

VLi

ventral median fissure vmnf ventral nucleus of the lat lemniscus

SGe

ventral orbital cortex

supramammillary decussation sumx

SphPal

VG

ventral geniculate nucleus, layer 1

suprachiasmatic nucleus, ventromedial part SChVM

sphenopalatine ganglion

VCA

ventral cochlear nucleus, posterior part, octopus cell area VCPO

solitary nucleus, ventral part SolV

supragenual nucleus

VA

VC

ventral column of the spinal cord vc

suprachiasmatic nucleus, dorsolateral part

Sph

ventral cochlear nucleus

ventral geniculate nucleus

sigmoid sinus sig

sphenoid nucleus

ventral anterior thalamic nucleus

ventral cochlear nucleus, posterior part VCP

SuS

superior thalamic radiation str

SolDL

vein v

ventral endopiriform nucleus VEn

septum neuroepithelium Sptne

solitary nucleus, dorsolateral part

vascular organ of the lamina terminalis VOLT

ventral cochlear nucleus, capsular part VCCap

SPO

superior rectus muscle SRec

vagus nerve ganglion 10Gn

ventral cochlear nucleus, anterior part

SOb

superior paraolivary nucleus

SFi

vagus nerve 10n

SMV

septohippocampal nucleus SHi

V

VLL

VO

ventral pallidum VP

spinal trigeminal nucleus, caudal part Sp5C

supramammillary nucleus

spinal trigeminal nucleus, interpolar part Sp5I

supramammillary nucleus, lateral part SuML

spinal trigeminal nucleus, oral part Sp5O

supramammillary nucleus, medial part SuMM

ventral posterior nucleus of the thalamus, parvicellular part VPPC

spinal trigeminal tract

supraoculomotor cap

ventral posterolateral thalamic nucleus

sp5

SuM

ventral part of claustrum

Su3C

spinal vestibular nucleus SpVe

supraoculomotor periaqueductal gray

splenium of the corpus callosum scc

supraoptic decussation sox

ventral reuniens thalamic nucleus

splenius capitis muscle

supraoptic nucleus

ventral spinocerebellar tract vsc

SplCa

Su3

VCl

VPL

ventral posteromedial thalamic nucleus VPM

SO

VRe

stapedius bone Stap

supraoptic nucleus, retrochiasmatic part SOR

ventral subiculum

stapedius muscle StapM

supraspinal nucleus SSp

ventral tegmental area VTA

sternomastoid muscle

supratrigeminal nucleus Su5

ventral tegmental area, rostral part VTAR

suspensory ligament

ventral tegmental decussation vtgx

StM

stigmoid hypothalamic nucleus Stg

SuspLig

stratum lucidum of the hippocampus SLu stria medullaris of the thalamus sm stria terminalis st strial part of the preoptic area StA striohypothalamic nucleus

StyMF

stylopharyngeus muscle

StyPh

SubC

subcoeruleus nucleus, alpha part SubCA subcoeruleus nucleus, dorsal part

SubCD

SubG

temporalis muscle

ventrolateral preoptic nucleus

VLPO

ventrolateral thalamic nucleus

VL

TempM TMJ

tensor palati muscle TPal

ventromedial hypothalamic nucleus VMH

tensor tympani muscle

ventromedial hypothalamic nucleus, central part VMHC

TT

ventromedial hypothalamic nucleus, dorsomedial part VMHDM

tongue Tongue

ventromedial hypothalamic nucleus, ventrolateral part VMHVL ventromedial nucleus of the hypothalamus shell VMHSh

triangular nucleus, lateral lemniscus

sublenticular extended amygdala, medial part EAM submammillothalamic nucleus SMT Sub

triangular septal nucleus, neuroepithelial zone TSne trigeminal ganglion 5Gn trigeminal nerve

subparafascicular thalamic nucleus SPF

5n

subparaventricular zone of the hypothalamus SPa subpeduncular tegmental nucleus SPTg

trigeminal nerve, ophthalmic division

substantia nigra SN substantia nigra, compact part, dorsal tier SNCD substantia nigra, compact part, medial tier SNCM substantia nigra, compacta part, ventral tier SNCV substantia nigra, lateral part SNL

SubVCx

VeCb

vesp

vomer Vom vomeronasal nerve

tth

4n

vn

trochlear nucleus 4N

X

trochlear nucleus shell region 4Sh

xiphoid thalamic nucleus

Xi

tuberal region of lateral hypothalamus TuLH tympanic branch of the glossopharyngeal nerve tympanic bulla

ty9

TyBu

tympanic membrane TyM

subthalamic nucleus STh

vestibule of the inner ear Vest

vitreous cavity (posterior chamber) of the eye Vitr

tympanic cavity TyC

SNR

vestibular root of the vestibulocochlear nerve 8vn

vestibulospinal tract

5oph

trigeminal-solitary transition zone 5Sol trochlear nerve

substantia innominata, basal part SIB

vestibular nerve ganglion VeGn

vestibulocochlear nerve 8n

trigeminal transition zone 5Tr trigeminothalamic tract

subpostrema area SubP

vertebral artery vert

vestibulocerebellar nucleus

trigeminal nerve, mandibular division 5man trigeminal nerve, maxillary division 5mx

subparafascicular thalamic nucleus, parvicellular part SPFPC

VMPO

ventromedial thalamic nucleus VM

trigeminal ganglion and trigeminal nerve 5Gn/5n

submedius thalamic nucleus, ventral part SubV

subventricular layer of developing cortex

ventromedial preoptic nucleus

TrLL

triangular septal nucleus TS

sublenticular extended amygdala, central part EAC

sulcus limitans sl

temporal bone, squamous part TempS

trapezoid body tz

sublenticular extended amygdala EA

VLH

ventrolateral periaqueductal gray VLPAG

trapezius muscle TzM

subincertal nucleus SubI

substantia nigra, reticular part

ventrolateral hypothalamic nucleus

transverse sinus trs

subiculum S

submedius thalamic nucleus

ventricular space of the eye Vent

TempP

transverse fibers of the pons tfp

SFO

VTT

ventral tuberomammillary nucleus VTM TeA

thyroid gland Thy

subcommissural organ SCO subgeniculate nucleus

ventral tenia tecta, layer 1 VTT1

terete hypothalamic nucleus Te

subcoeruleus nucleus, ventral part SubCV subfornical organ

tectal gray TG

temporomandibular joint

subbrachial nucleus SubB subcoeruleus nucleus

T

temporal bone, petrosal part

stylohyoid muscle StyHy

VTg

ventral tenia tecta

temporal associatin cortex

styloglossus muscle StyGl stylomastoidforamen

ventral tegmental nucleus

tectospinal tract ts

StHy

VS

Z zona incerta, caudal part ZIC zona incerta, dorsal part

ZID

zona incerta, rostral part ZIR zona incerta, ventral part ZIV

U utricle

zona layer of the superior colliculus Zo Utr

zona limitans ZL zygomatic arch

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

ZygA

XVII

Index of Abbreviations

8n

vestibulocochlear nerve 161

29, 34, 88-91, 94, 159,

8vn vestibular root of the vestibulocochlear nerve 25, 83-85, 89, 91, 152, 154-155, 159-160

The abbreviations are listed in alphabetical order. Each abbreviation is followed by the structure name and the number of the figures on which the abbreviation appears.

9/10/11n glossopharyngeal, vagus, and accessory nerves 28-29, 94-98, 163 9/10n glossopharyngeal and vagus nerves 93 9Cb

9th cerebellar lobule

97, 101-102, 167-176

9n glossopharyngeal nerve 30, 93-95

AmbC ambiguus nucleus, compact part 93-96, 165-166 AmbL ambiguus nucleus, loose part 98-99, 169-171

B basal nucleus (Meynert) 15-16, 63-64, 66, 68, 124-129

AmbSC ambiguus nucleus, subcompact part 97, 167-168

BAC

Amg amygdala 13, 21 AMV anteromedial thalamic nucleus, ventral part 127-129 AngT angular thalamic nucleus 65, 129-133

1 layer 1 of cortex 56-57, 59, 64, 110, 137

10Cb 10th cerebellar lobule (nodule) 164-168

1Cb

1st cerebellar lobule (lingula)

10Gn vagus nerve ganglion 25, 83-87, 90, 162-163

AO

1Cx

layer 1 of developing cortex

3-20, 22-24, 26-29

10N

AOB accessory olfactory bulb 2, 45-46

1n

olfactory nerve or its rootlets

1-5, 42-44, 104-105

94-95, 163

2 layer 2 of cortex 56-57, 59, 64-66, 68-70, 72-75, 108-139 2/3Cb 2Cb

2nd and 3rd cerebellar lobules 2nd cerebellar lobule

93, 161-163

158-160

2n optic nerve 5-9, 52-63, 108-110, 112-124

dorsal motor nucleus of vagus 166-174

96-102,

anterior chamber of the eye

anterior olfactory nucleus

brachium of the inferior colliculus 144-157

11N accessory nerve nucleus 35-37, 102-103, 174-176

AOE anterior olfactory nucleus, external part 2, 47, 105-106

BL

basolateral amygdaloid nucleus

BLA

11n root of accessory nerve 174

AOL anterior olfactory nucleus, lateral part 47-49, 105-107

basolateral amygdaloid nucleus, anterior part 18, 68-72, 128-134

BLP

basolateral amygdaloid nucleus, posterior part 71-75, 133-140

BLV

basolateral amygdaloid nucleus, ventral part 18-19, 69-72, 131-136

12N hypoglossal nucleus 35-38, 95-102, 165-175

AOP

12n root of hypoglossal nerve 28-29, 94, 96-101, 167-170, 172

AOrb alar orbital bone 42-47, 49, 52-54

3V 3rd ventricle 8-26, 59-70, 72, 74-76, 121-142 4

layer 4 of cortex

4/5Cb 4Cb

110

4th and 5th cerebellar lobules 4th cerebellar lobule

94, 162-163

161

hypoglossal canal

30, 92-94, 97, 166, 170,

12GH hypoglossal nucleus, geniohyoid part 170

3PC oculomotor nucleus, parvicellular part 32-34, 80-82, 149

96-98, 167

anterior olfactory nucleus, posterior part 49-50, 109-112

AOV anterior olfactory nucleus, ventral part 47, 105-107

A

AOVP anterior olfactory nucleus, ventroposterior part 48-50, 108-110

a artery 108, 117, 140-141, 147 A1 A1 noradrenaline cells 101-103, 173-176

AP

A1/C1 A1 noradrenaline cells/C1 adrenaline cells 171-172 A11 A11 dopamine cells 25, 69-71, 73, 79, 135-142

4N trochlear nucleus 35-36, 83-84, 150-153

A13 A13 dopamine cells 65, 67-70, 132-134

4n

A14 A14 dopamine cells 73, 129

trochlear nerve 9-15, 19-20, 59-64, 70-71, 73, 76-78, 82, 121, 143, 146-147

nucleus of the brachium of the inferior colliculus 31-35, 79-85, 146-155

bic

3Cb

3n oculomotor nerve 9-15, 19-20, 59-64, 69, 71-73, 75-77, 121, 143, 146-147

BIC

AOD anterior olfactory nucleus, dorsal part 47-49, 105-107

AOM anterior olfactory nucleus, medial part 47-49, 106-107

3N oculomotor nucleus 31-34, 80-82, 148-149

21-22, 24-26, 28, 31-32, 77-99,

10n vagus nerve 30, 165

12C

160

basilar artery 146-171

BCo basal nucleus, core 127

3

3 layer 3 of cortex 56-57, 59, 64-66, 68-70, 72-75, 108-139 3rd cerebellar lobule

61-62,

Bar Barrington’s nucleus 33-35, 87-91, 157-160 bas

2, 4-5

bed nucleus of the anterior commissure 122-123

BAOT bed nucleus of the accessory olfactory tract 16, 67-70, 128-132

ANS accessory neurosecretory nuclei 64-66, 127-130 AntCh

35-39, 95-103,

B

area postrema

39-40, 101, 168-173

16-17, 19-20

basomedial amygdaloid nucleus

19-20

BMA basomedial amygdaloid nucleus, anterior part 16-18, 65-70, 128-133 BMP basomedial amygdaloid nucleus, posterior part 70-74, 133-138 Bo

Botzinger complex

93-94, 163-165

BOcc basioccipital bone 18-23, 25-26, 28-29, 37-38, 81-87, 89-90, 93-97, 162-163

Apex apex of cochlea 78 APF

BM

31-36, 79-85,

anterior perifornical nucleus 62

APir amygdalopiriform transition area 74-77, 79-80, 138-144

bsc brachium of the superior colliculus 22, 26, 28, 69-75, 136-140 BSph basisphenoid bone 14, 17, 65-69, 71, 73-74, 77-80

A4 A4 noradrenaline cells 94

APit anterior lobe of the pituitary 17-20, 76-80, 143, 146

A5 A5 noradrenaline cells 24, 85, 88-89, 154-158

apmf ansoparamedian fissure 164-168, 170-172

A7 A7 noradrenaline cells 26-29, 83-84, 86, 152-153, 155

BTel basal telencephalon 5-10, 13

APT anterior pretectal nucleus 24-29, 72-77, 137-138, 141-142, 144-146

AA anterior amygdaloid area 14-15, 63-68, 124-131

BTelne basal telencephalon, neuroepithelial zone 5-8, 10-16, 20-22

ac anterior commissure 11, 53, 56-61, 121-123

APTD anterior pretectal nucleus, dorsal part 139-140, 143

aca anterior commissure, anterior part 4-10, 49-52, 54-55, 109-120

5Gn/5n trigeminal ganglion and trigeminal nerve 15, 65, 67, 70-72

APTV anterior pretectal nucleus, ventral part 139-140, 143

Acb accumbens nucleus 5-8, 51-53

Aq

5man trigeminal nerve, mandibular division 11-14, 16, 71-73

Acbne

accumbens nucleus neuroepithelium

AcbSh

accumbens nucleus, shell

4Sh trochlear nucleus shell region 150-151, 153 4V 4th ventricle 26-41, 87-100, 158-169 5ADi motor trigeminal nucleus, anterior digastric part 156-157 5Cb

5th cerebellar lobule

164-166

5Gn trigeminal ganglion 14, 16-22, 66, 68-69, 73-79, 143, 146-147

5mx trigeminal nerve, maxillary division 1-13, 42-62, 64, 104-105, 108, 110, 112-113, 116-117, 121 5N

motor trigeminal nucleus 154-157

26-27, 29, 84-86,

AcbC accumbens nucleus, core 54-58, 112-119

aci anterior commissure, intrabulbar part 105-107 anterior cortical amygdaloid nucleus 64-70, 125-133

5n trigeminal nerve 20-23, 63 9-13,

5Sol trigeminal-solitary transition zone 29, 31, 34-37, 39-40, 89-100, 161-170 5Tr trigeminal transition zone 158-159 5TT

motor trigeminal nucleus, tensor tympani part 24-28, 82-85, 151-155

6Cb

6th cerebellar lobule

95-102, 165-169

6N abducens nucleus 27-30, 87-88, 159-160 6n root of abducens nerve 9-15, 19-20, 59-65, 71-73, 75-76, 78-80, 87, 89, 121, 146, 159 6RB abducens nucleus, retractor bulbi part 87, 157 7Cb 7DI

7th cerebellar lobule

102-103, 166-174

facial nucleus, dorsal intermediate subnucleus 25, 87-89, 91, 159-161

7DL facial nucleus, dorsolateral subnucleus 87, 89, 91, 159-161 7DM facial nucleus, dorsomedial subnucleus 87-89, 91, 159-161 7Gn 7L

a

25,

80, 82

facial nucleus, lateral subnucleus 159-161

25, 87-89, 91,

7N facial nucleus 23-24, 26-29, 90, 92, 158, 162-163

53-58, 110-119

acer anterior cerebral artery 4-7, 55-56, 61, 115-128 ACo

5oph trigeminal nerve, ophthalmic division 59-60, 62, 64, 121

4

14-18,

acp anterior commissure, posterior part 11-14, 59, 61, 63-66, 121-127

8cn cochlear root of the vestibulocochlear nerve 20-24, 84-87, 92, 154-159, 162

C2

C2 adrenaline cells

94

CA1 field CA1 of the hippocampus 65-69, 75, 128-134, 137-142 CA2 field CA2 of the hippocampus 65-69, 128-139

Ary arytenoid cartilage 20-21

AH anterior hypothalamic area 14-16, 66

asc7 ascending fibers of the facial nerve 30

cav cavernous sinus 8-11, 13-14, 59, 61-62, 110, 113-117, 121

AHA anterior hypothalamic area, anterior part 12-13, 65, 127-129

ASCC anterior semicircular canal 26, 28-34, 85, 87, 89-95

CB cell bridges of the ventral striatum 53-56, 59, 115-117, 119-120, 122

AHC anterior hypothalamic area, central part 66-68, 129-131

asp anterior spinal artery 33

Cb

ASph alisphenoid bone 10-17, 58-64, 66, 68-77, 121

cbw

cerebellar white matter

AHiAL amygdalohippocampal area, anterolateral part 71-73, 135-138

ASt amygdalostriatal transition area 68

cbx

cerebellar commissure

AtAx

CC central canal 33-38, 170-176

AHiPL amygdalohippocampal area, posterolateral 74-75, 139-140

ATg

anterior tegmental nucleus

ATh

anterior thalamic region

AHiPM amygdalohippocampal area, posteromedial part 74-80, 139-144

Atlas

atlas

AtOc

atlantooccipital joint

AHP anterior hypothalamic area, posterior part 17, 67-68, 130-132 AID agranular insular cortex, dorsal part 50-67, 107-110, 111-121 AIP agranular insular cortex, posterior part 68-69, 122-132

alar nucleus

101-103, 169-175

ArcLP arcuate hypothalamic nucleus, lateroposterior part 75, 139-141

C1/RVL rostral ventrolateral reticular nucleus 93-94

af amygdaloid fissure 138-143

Al

8th cerebellar lobule

ArcL arcuate hypothalamic nucleus, lateral part 71-74, 134-138

C1/CVL C1 cells and caudoventrolateral reticular nucleus 95

CAT nucleus of the central acoustic tract 22, 82-84, 152-154

nucleus of the ansa lenticularis

8Cb

ArcD arcuate hypothalamic nucleus, dorsal part 71, 74, 134-137

90, 92, 161-168

ArcMP arcuate hypothalamic nucleus, medial posterior part 75-76, 139-142

AL

87-89,

Arc arcuate hypothalamic nucleus 16-22, 24-26, 69-70, 132-133

C1 adrenaline cells

C1/A1 C1 adrenaline cells and A1 noradrenaline cells 97-98, 100, 169-170

ADig anterior belly of the digastric muscle 1, 3

7SH facial motor nucleus, stylohyoid part 27-28, 89, 92, 158-163

7VM facial nucleus, ventromedial subnucleus 91, 159-161

C1

26-27, 29-41, 76-97, 143-157

CA3 field CA3 of the hippocampus 63-69, 73-77, 126-143

AD anterodorsal thalamic nucleus 14, 63-64, 124-127

AIV agranular insular cortex, ventral part 50-67, 107-121

facial nucleus, ventral intermediate subnucleus 87-89, 91, 159-161

C

ArcM arcuate hypothalamic nucleus, medial part 71-74, 134-138

7n facial nerve 19-26, 80-92, 150-159

7VI

aqueduct

BStap base of stapes 23-25

68

59-60, 121

Alar alar ligament of dens 30-31

atlantoaxial joint

30-31, 103 33, 83-84, 152-153

cc

cerebellum

30-31, 33-34, 36, 38-40, 86-90

corpus callosum

156-173 38

57-62, 64-65, 101, 115-134

CCrus common crus of the semicircular canals 30-35, 93-94, 167-168

13

25-26, 28-31, 33-41, 98-100, 103

CD

30-31

cochlear duct

19-25, 80-87, 89-91, 153-154

Au1 primary auditory cortex 70-79, 131-143

Ce central amygdaloid nucleus 16-20, 72

AuD secondary auditory cortex, dorsal area 70-79, 131-144

CeAu cervicoauricular muscle 31, 33-38 CeC

Aud auditory tube 16 AudC auditory tube cartilage 17 AuV secondary auditory cortex, ventral area 70-79, 131-143 AV

anteroventral thalamic nucleus

CeCv central cervical nucleus of the spinal cord 101, 103, 171-176 CeL

central amygdaloid nucleus, lateral division 68-70, 129-133

CeM

central amygdaloid nucleus, medial division 65-70, 128-133

14, 65, 123-125

AVDM anterovent thalamic nucleus, dorsomedial part 63-64, 126-129

CEnt caudomedial entothinal cortex 81-82, 145-152

alv alveus of the hippocampus 68, 127-131, 133-147

AVPe anteroventral periventricular nucleus 123

AM anteromedial thalamic nucleus 14-15, 63-66, 125-131

AVVL anteroventral thalamic nucleus, ventrolateral part 63-64, 126-129

Cg cingulate cortex 14

Amb

Axis axis (C2 vertebra) 28-31, 33-41, 99-100

Cg1 cingulate cortex, area 1 50-62, 108-126

azac

Cg2 cingulate cortex, area 2 49, 54-61, 115-126

ambiguus nucleus

30, 32-36

58-60,

central amygdaloid nucleus, capsular part 67-71, 99, 129-134

azygous anterior cerebral artery 5, 112-114

CG central gray 29-32, 93 cg cingulum 54-70, 112-138

CGA central gray, alpha part 28, 88-89, 159-160

XVIII

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

CGB

central gray, beta part

29, 87, 89, 158-159

DG dentate gyrus 18-20, 24, 64-69, 73-80, 146

H

ECu external cuneate nucleus 38-41, 97-101, 166-170

CGG central gray, gamma part 88, 159-160

DH

CGn

dhc dorsal hippocampal commissure 64, 66, 127-145

EGL external granular layer of developing cerebellum 31-40, 92-103, 153-176

DI

ELS endolymphatic sac 28-35, 87, 89-99

cochlear (spiral) ganglion 154, 157

CGO

central gray, nucleus O

20-24, 79-87, 92-93, 28, 89, 159

chp choroid plexus 12-22, 33-37, 131, 162, 166-169 CIC

central nucleus of the inferior colliculus 157-164

CL

centrolateral thalamic nucleus 127-137

87-93,

dorsal horn of spinal cord

dysgranular insular cortex

37-41

52-69, 109-132

DIEnt dorsal intermediate entorhinal cortex 145-150 Dk

nucleus of Darkschewitsch 143-149

65, 67-70,

81,

emv emissary vein 28-29

26-29, 74-79,

EnO 74-81,

Cl claustrum 8-16, 50-59, 69, 109

DLEnt dorsolateral entorhinal cortex 136-147

Clav

DLG

18-24, 69-73,

clavicle

20

CLi caudal linear nucleus of the raphe 33-34, 81-83, 149-152

DLL

CM central medial thalamic nucleus 16-20, 22-24, 63-65, 67-70, 125-136

DLO

CnF

dlo

Com

cuneiform nucleus

35-38, 83-94, 154-160

commissural nucleus of the inferior colliculus 26, 90-95, 159-162

1-8, 42-44, 47, 49, 104, 110,

32-37,

Entne entorhinal cortex, neuroepithelial zone 22-27 EpiG

epiglottis

17

48-49, 106

EPl external plexiform layer of the olfactory bulb 1-2, 42-46, 104-107

2, 105

EpP epipeduncular nucleus 74, 142-143

DLPAG dorsolateral periaqueductal gray 77-85, 87-92, 145-159

ESO

episupraoptic nucleus

Cop copula of the pyramis 102-103, 168-173

DMC dorsomedial hypothalamic nucleus, compact part 71-72, 135-136, 166

EVe nucleus of origin of efferents of the vestibular nerve 27-28, 87-89, 158-160

DMD dorsomedial hypothalamic nucleus, dorsal part 73, 133-136

EW Edinger-Westphal nucleus Eye

cp cerebral peduncle 24-33, 79-82, 84, 137-150

DMPAG dorsomedial periaqueductal gray 77-92, 144-161

CPu caudate putamen (striatum) 7-20, 52-66, 68-72, 111-134

DMSp5 dorsomedial spinal trigeminal nucleus 161-169

CPune caudate putamen, neuroepithelial zone 4-19

DMTg dorsomedial tegmental area 27-29, 83-88, 155-158

6, 8-10,

Cornea cornea 2-6, 44-47, 105 Corti organ of Corti 20, 87, 153-154

cpx

carotid plexus

77-80

Eyelid

HMall

handle of malleus

20-22, 80-81

HPtg hamulus of the pterygoid bone 74-75

14-15, 72,

HSCC horizontal semicircular canal 28-31, 90-96 HSCCA horizontal semicircular canal ampulla 26, 28, 85-87, 89

I I

79-80, 148-149

intercalated nuclei of the amygdala 16-18, 65, 67-68, 70-72, 128-129, 131, 133-136

I8 interstitial nucleus of the vestibulocochlear nerve 157-158

8-9, 42-43, 48-49, 53-54, 112

eyelid

Hi hippocampal region 14-23, 70-72

1-7, 42-44, 104-105, 108

ExOrb exorbital gland 74, 78 eye

Hem hemisphere of cerebellum 91-101

Hyoid hyoid bone 16-18, 20

DM dorsomedial hypothalamic nucleus 17-21, 69-72, 74-75, 137-139

Cor coronoid process of the mandible 55-59, 61

HDB nucleus of the horizontal limb of the diagonal band 11-13, 54-66, 117-130

HyGl hyoglossus muscle 5, 8-12, 14

Cond condylar process of mandible 15-18, 63-64, 66-69, 71-74

ethmoid bone

habenular nuclei 16-21

hbc habenular commissure 70-72, 136-137

HStap handle of stapes 24

65-67, 127-130

Eth ethmoid thalamic nucleus 25, 46, 73-74, 140-142 EthB

Hb

hif hippocampal fissure 65, 76-77, 128-141

EP entopeduncular nucleus 18-19, 67-69, 130-134

dorsal nucleus of the lateral lemniscus 82-88, 153-157 dorsal lateral olfactory tract

enamel organ 116-117

Ent entorhinal cortex 23-27

dorsal lateral geniculate nucleus 131-140

dorsolateral orbital cortex

eml external medullary lamina 65, 68, 126, 132-135, 137-138

HardG Harderian gland 43-47, 49-53, 104-105, 110, 112-114

I9Gn inferior ganglion of the glossopharyngeal nerve 28, 90-94, 163

2-7, 42, 53

ia internal arcuate fibers 176

F

IAD

F nucleus of the fields of Forel 25, 72-73, 139-140

interanterodorsal thalamic nucleus 126-127

63-64,

DMV dorsomedial hypothalamic nucleus, ventral part 73, 135-136

f fornix 12-17, 19-22, 59-76, 121-143

ialn inferior alveolar nerve 1, 5, 7-10, 63, 65, 67-69

Fat loculated brown fat 33-41

IAM

DP dorsal peduncular cortex 50-53, 109-115

FC fasciola cinereum 65-66, 130-133, 135

dpal descending palatine artery 1-3, 6, 43-44

FF fields of Forel 73, 138-139, 141-142

IAud internal auditory meatus 86-87

Crus2 crus 2 of the ansiform lobule 102-103, 155, 159-172

DpG deep gray layer of the superior colliculus 77-87, 143-158

fi fimbria of the hippocampus 11-22, 62-73, 120-136

IB interstitial nucleus of the medulla 175-176

Fl flocculus 91-98, 157-166

IC inferior colliculus 33, 36-41, 94-102

csc commissure of the superior colliculus 27, 29, 74-76, 78, 143-144

DPGi dorsal paragigantocellular nucleus 28, 30-33, 89-94, 160-165

FMag

ic internal capsule 12-22, 60-78, 121-140

cst commissural stria terminalis 15, 67-69, 128-131, 133

DPO

CrP

cribriform plate of the ethmoid 104

1-4, 42-46, 49,

Crus1 crus 1 of the ansiform lobule 156-171

Ctd

carotid canal

CtdB cty

100-101,

77-78

carotid body 87, 89-92, 94 chorda tympani nerve

30-31

65-66,

fmi forceps minor of the corpus callosum 50-53, 110-114

icf intercrural fissure 159-171

DpWh deep white layer of the superior colliculus 78-87, 144-156

fmj forceps major of the corpus callosum 67-74, 136-145

DR

ICjM islands of Calleja, major island 54, 113, 116-117

fr fasciculus retroflexus 20-31, 69-77, 132-146

dorsal periolivary region

dorsal raphe nucleus

DR3V

67-70, 72

foramen magnum

interanteromedial thalamic nucleus 128-130

156

35-36, 83-84

dorsal recess of third ventricle

15-20

Fr3

ICj islands of Calleja 55-59, 111-112, 114-121, 124

frontal cortex, area 3

50-52, 107-111

icp inferior cerebellar peduncle (restiform body) 29-35, 91-93, 95-99, 160-166

frontal assocn cortex

46-47, 105-106

ictd

Cu cuneate nucleus 41, 99-103, 168-176

DRC dorsal raphe nucleus, caudal part 90, 158-161

FrA

cu cuneate fasciculus 37-41, 100-103, 173-176

DRD dorsal raphe nucleus, dorsal part 81-82, 85-89, 150-157

Fro

DRGn dorsal root ganglion 35, 37

Fro/Par frontal and parietal bones 86

IEn

DRI dorsal raphe, interfascicular part 83-86, 152-155

Fu bed nucleus of stria terminalis, fusiform part 59-60, 121-122

IF interfascicular nucleus 28-30, 76-80, 144-148

DRL

dorsal raphe nucleus, lateral part 152-155

FVe F cell group of the vestibular complex 95, 165-166

DRV

dorsal raphe nucleus, ventral part 81-82, 85-88, 149-157

DS

dorsal subiculum

CuR cuneate nucleus, rotundus part 100-103, 171-175 CV2

second cervical vertebra

36

CVL

caudoventrolateral reticular nucleus

167

CVL/C1 caudoventrolateral reticular nucleus and C1 cells 96 Cx cerebral cortex 83-85 Cx1

developing cortex, layer 1

21

CxA cortex-amygdala transition zone 14-16, 59-60, 62-63, 66-67, 131 CxA1 cortex-amygdala transition zone, layer 1 64-65, 126, 128-130 CxA2 cortex-amygdala transition zone, layer 2 61 Cxne neuroepithelial zone of developing cortex 3-27, 29 CxP cortical plate 3-29

dsc

85-86,

69, 71-77, 135-148

dorsal spinocerebellar tract 173-176

101-103, 169,

frontal bone 2-14, 42-50, 52, 54-58, 60, 104-105, 108-110, 112-113, 116

IL infralimbic cortex 50-53, 109-114

g7 genu of the facial nerve 27-28, 87, 89, 160

ILL

intermediate nucleus of the lateral lemniscus 29-31, 79-82, 151-154

Ge5 gelatinous layer of the caudal spinal trigeminal nucleus 175

IM

intercalated amygdaloid nucleus, main part 130-131

DTg dorsal tegmental nucleus 34-35, 89, 91-92

GeGl genioglossus muscle 1, 3, 5, 8

IMA

DTgC dorsal tegmental nucleus, central part 158-159

GeHy geniohyoid muscle 3, 5, 16-17

intramedullary thalamic area 134-139

IMD

intermediodorsal thalamic nucleus 129-135

90,

Gem gemini hypothalamic nucleus 25, 72, 139-141 GI granular insular cortex 54-69, 110-112, 114-132

DTM dorsal tuberomammillary nucleus 74-75, 139-140

GiA

gigantocellular reticular nucleus, alpha part 24-28, 87-91, 159-164

DAx dens of the axis 30-31, 100

DTr dorsal transition zone 108-109

GiV

DC dorsal cochlear nucleus

DTT dorsal tenia tecta 48-55, 107-113

gigantocellular reticular nucleus, ventral part 29-30, 92-95, 165-166

32-34, 93-96, 159-160

dorsal tegmental decussation 149

E

DCIC dorsal cortex of the inferior colliculus 159-164

90-93,

DCl dorsal part of claustrum 60-66, 68, 110-132 DCMo dorsal cochlear nucleus, molecular layer 160-165

E

ependyma and subependymal layer

140

EA sublenticular extended amygdala 14-16, 63, 67, 131 EAC sublenticular extended amygdala, central part 64-66, 124-130

dcs dorsal corticospinal tract 37-41

EAM sublenticular extended amygdala, medial part 18, 20-26, 65-66, 77-85, 128-130

dcw deep cerebral white matter 51-52, 56, 64-66, 69, 71-73, 75, 79, 81-82, 112, 124-132, 135-140, 142-149

ec external capsule 5-13, 53-62, 64-66, 69-70, 113-116, 118-134

DEn

dorsal endopiriform nucleus 107-139

df dorsal fornix 62-63, 120-125

12, 17-18, 50-75,

24-26, 28-36,

Gl glomerular layer of the olfactory bulb 1-2, 42-46, 104-107

DCDp dorsal cochlear nucleus, deep core 161-164 DCFu dorsal cochlear nucleus, fusiform layer 161-164

IGL intergeniculate leaf 18-24, 69-73, 132-141

dsc/oc dorsal spinocerebellar tract and olivocerebellar tract 30-32, 163-168, 170-172

dtgx dorsal hypothalamic area 19, 69, 133-134

IG indusium griseum 8-12, 54-63, 114-135

G

gigantocellular reticular nucleus 87-99, 159-169

DA

intermediate endopiriform nucleus 50-60, 62-64, 108-120, 121-126

ijugv internal jugular vein 21, 23, 28-30, 96-97

Gi

D3V dorsal 3rd ventricle 66-74, 126-136, 138-139

ICx intermediate cortical layer 4-28

gcc genu of the corpus callosum 54, 56

DTgP dorsal tegmental nucleus, pericentral part 90, 157-161

D

internal carotid artery 8-12, 14-21, 23, 69, 71-82, 85, 87, 89-92, 129-132, 134-135

ECIC external cortex of the inferior colliculus 34-35, 80-93, 150-166 Ect ectorhinal cortex

70-82, 133-151

ectd external carotid artery 91-92

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

iml internal medullary lamina 133-134, 136 In intercalated nucleus of the medulla 35, 37-38, 95-96, 167-168 InC interstitial nucleus of Cajal 28-30, 74-81, 144-149 Inc

incus

Inf

infundibulum

InfM

GP globus pallidus 13-18, 59, 62-65, 67-69, 123-132

InG

gr gracile fasciculus 37-41, 103, 175-176 GrA granule cell layer of the accessory olfactory bulb 158 GrC granule cell layer of cochlear nuclei 92-94, 159-163 GrCb granule cell layer of the cerebellum 162-164, 166-176

154-156,

GrDG granular layer of the dentate gyrus 126-145 GrO

granular cell layer of the olfactory bulb 42-43, 47, 104-107

2,

65-69,

IMG amygdaloid intramedullary gray 72, 131-134

Gonial gonial process 72-75 Gr gracile nucleus 1, 98-103, 169-176

70-72, 132,

22-23, 27, 77, 81 139

inferior meatus

1, 42-45

intermediate gray layer of the superior colliculus 76-87, 143-158

InPl inner plexiform layer of the retina 2-4, 6-8, 43-46, 49-53, 104-105, 108-110, 112 Ins insular cortex 8-16 Int interposed cerebellar nucleus 93-98 IntA interposed cerebellar nucleus, anterior part 23-24, 37-39, 161-164 IntDL interposed cerebellar nucleus, dorsolateral hump 162-164 IntP interposed cerebellar nucleus, posterior part 37-38, 163-167

XIX

IntPPC interposed cerebellar nucleus, posterior parvicellular part 165

LaVM lateral amygdaloid nucleus, ventromedial part 133-139

InWh intermediate white layer of the superior colliculus 74, 76-87, 143-158

LC locus coeruleus 32, 34-35, 89-91, 158-162

IO

LD laterodorsal thalamic nucleus 16, 65-66

inferior olivary nucleus

lc

29-30

IOA inferior olive, subnucleus A of medial nucleus 99-101, 170-174 IOB inferior olive, subnucleus B of medial nucleus 99-102, 169-173 IObCa inferior oblique capitis muscle IOBe inferior olive, beta subnucleus 168-173

31, 34 99-101,

lateral column of the spinal cord 33-39

Ld lambdoid septal zone 57, 117, 119 LDDM laterodorsal thalamic nucleus, dorsomedial part 67-68, 126-132 LDTg laterodorsal tegmental nucleus 155-161

32-35, 86-92,

LDTgV laterodorsal tegmental nucleus, ventral part 87-89, 155-157

IOC inferior olive, subnucleus C of medial nucleus 99-101, 169-173

LDVL laterodorsal thalamic nucleus, ventrolateral part 67-68, 126-133

IOD

Lens lens 2-6, 45, 47, 50-51, 105, 108-109

inferior olive, dorsal nucleus 164-171

31-35, 95-100,

LEnt lateral entorhinal cortex 82, 133-135, 148-150

IODM inferior olive, dorsomedial cell group 166-167

lfp longitudinal fasciculus of the pons 24-25, 77, 79-81, 147-152

IOK

inferior olive, cap of Kooy of the medial nucleus 99-101, 171-173

lga

IOM

inferior olive, medial nucleus 164-168

lgn lingual nerve 68

31-36, 94-98,

infraorbital foramen

53

Li linear nucleus of the medulla 95-96, 166-168

interpeduncular nucleus, apical subnucleus 79-81, 149-150

ll

IPAC interstitial nucleus of the posterior limb of the anterior commissure 58-65, 120-127 IPC

LHb lateral habenular nucleus 22, 64-66, 68-71, 127-128

LHbM lateral habenular nucleus, medial part 129-137

IP interpeduncular nucleus 27, 32

interpeduncular nucleus, caudal subnucleus 31, 78-80, 145-150

lateral lemniscus

27, 79-83, 86-87, 148-156

LM lateral mammillary nucleus 23-24, 76-77, 141-144 LMol lacunosum moleculare layer of the hippocampus 128-142 LO lateral orbital cortex

48-51, 105-110

IPDL interpeduncular nucleus, dorsolateral subnucleus 78-80, 147-149

lo

2-13, 46-48, 51-52, 54-64,

IPDM interpeduncular nucleus, dorsomedial subnucleus 147-148

LOT nucleus of the lateral olfactory tract 14-15, 129

IPF interpeduncular fossa 27, 30-31, 76-78, 145-146 IPI

interpeduncular nucleus, intermediate subnucleus 78-80, 148-150

IPit intermediate lobe of the pituitary 18-19, 77-79, 143 IPL

interpeduncular nucleus, lateral subnucleus 46, 78, 104, 146-149

31,

IPl internal plexiform layer of the olfactory bulb 1-2, 42-45, 106 IPR

interpeduncular nucleus, rostral subnucleus 77-79, 145-149

IRec inferior rectus muscle 7-8, 51, 54-56, 112

lateral olfactory tract 105, 107-125

LOT1 nucleus of the lateral olfactory tract, layer 1 66, 127-128 LOT2 nucleus of the lateral olfactory tract, layer 2 65, 67 LP

lateral posterior thalamic nucleus 139-145

17-30, 72-75,

LPAG lateral periaqueductal gray 77-92, 145-160 LPal levator palati muscle 17 LPB lateral parabrachial nucleus 32, 34-35, 86-90, 92-93, 158-161 LPBC lateral parabrachial nucleus, central part 156-157

Iris iris 4, 6, 45, 47

LPBE lateral parabrachial nucleus, external part 33, 87-89, 156-160

IRt intermediate reticular nucleus 26-36, 87-103, 157-176

LPBI

IS

inferior salivatory nucleus

30, 92-94, 162-164

IVF interventricular foramen 12-14, 62-63, 123

lateral parabrachial nucleus, internal part 160-161

LPBS lateral parabrachial nucleus, superior part 156-157 LPGi lateral paragigantocellular nucleus 23-32, 87-95, 97, 158-167

J JPLH juxtaparaventricular part of lateral hypothalamus 65-67, 129-130

LPLR lateral posterior thalamic nucleus, laterorostral part 69-71, 134-138

JugF jugular foramen 30-31, 93-97, 162-163, 167

LPMR lateral posterior thalamic nucleus, mediorostral part 69-71, 133-138 LPO lateral preoptic area 11-12, 58-64, 119-126

K KF Kˆlliker-Fuse nucleus 30-32, 84-87, 153-159

LPS levator palpebrae superioris muscle 4-7, 49, 51-52, 108-110 LPtA lateral parietal association cortex 70, 129-131

L

LPtg lateral pterygoid muscle 10-16, 58-67, 69-73

LA lateroanterior hypothalamic nucleus 65-66, 127-130 La

lat amygdaloid nucleus

LAcbSh

12-14,

16-20, 68-75

lateral accumbens shell

56-57, 117

LaDL lateral amygdaloid nucleus, dorsolateral part 130-137 Lar larynx 20 LarPh

laryngopharynx

18, 20-21

Lat lateral (dentate) cerebellar nucleus 35, 37-39, 93-97, 159-164 LatPC lateral cerebellar nucleus, parvicellular part 93-94, 161-164 LaVL lateral amygdaloid nucleus, ventrolateral part 133-134

XX

LR4V lateral recess of the 4th ventricle 30-38, 90-98, 157-168 LRec lateral rectus muscle 7-9, 54-57, 112 LReCa lateral rectus capitis muscle 22-26 LRt lateral reticular nucleus 33-36, 97-102, 168-174 LRtPC lateral reticular nucleus, parvicellular part 97-99, 169-173 LRtS5 lateral reticular nucleus, subtrigeminal part 168-171 LS

lateral septal nucleus

LSS lateral stripe of the striatum 54-56, 58-62, 116-128

5-11

LSD lateral septal nucleus, dorsal part 53-62, 114-124 LSI lateral septal nucleus, intermediate part 50-61, 112-122

MGV medial geniculate nucleus, ventral part 75-78, 140-145

LSV lateral septal nucleus, ventral part 53-60, 113-121 LT lateral terminal nucleus of the accessory optic tract 74-76, 142

MHb medial habenular nucleus 22, 64-69, 71, 126-133, 135-137 Mi

LTer lemina terminalis 11, 59-61, 122-123 Lth lithoid nucleus 26, 73-75, 141-143 LV lateral ventricle 3-26, 51-65, 68, 73-76, 78, 80, 112-137, 139-146 LVe lateral vestibular nucleus 30-31, 91-93, 161-164 LVPO lateroventral periolivary nucleus 154-157

84-86,

mitral cell layer of the olfactory bulb 104-106

1-2, 42-46,

MiA mitral cell layer of the accessory olfactory bulb 104-105 MidM

middle meatus

1-3, 43-50, 108, 110

MiTg microcellular tegmental nucleus 34-35, 81-88, 150-155 ML medial mammillary nucleus, lateral part 23-26, 74-76, 141-145 ml medial lemniscus 18-28, 30-31, 70-77, 79, 81, 85-86, 132-134, 136-137, 139-160, 162-173

M M1 primary motor cortex 49-69, 107-128 M2

secondary motor cortex

mlf medial longitudinal fasciculus 27-36, 78-86, 88, 94, 145-176

48-69, 107-128

m5 motor root of the trigeminal nerve 19, 25, 27, 75-79, 81-82, 143, 146-153, 155-157 MA3 medial accessory oculomotor nucleus 28-30, 33, 77-79, 145-147 Mall

LHbL lateral habenular nucleus, lateral part 129-131, 133, 135-137

IOVL inferior olive, ventrolateral protrusion 168-170 IPA

LgCa longus capitis muscle 20-24, 82, 87, 89

LH lateral hypothalamic area 67, 75 31-33, 94-98,

iorb infraorbital artery 1-3, 50-51, 53-54, 56-58 IOrbF

3, 5-12

LgsCa longissimus capitis muscle 28-31, 33-41

iopha inferior ophthalmic artery 8 IOPr inferior olive, principal nucleus 165-170

lingual artery

MGM medial geniculate nucleus, medial part 73, 75-78, 141-143

LSO lateral superior olive 85-86, 155-157

malleus

20-21, 23, 77-81, 84-85

Man mandible 1-14, 54-62, 70, 72 masa

masseteric artery

mlx medial lemniscus decussation 101, 175 MM medial mammillary nucleus, medial part 23-26, 74-76, 141-144 MnA median accessory nucleus of the medulla 102, 175-176 MnM medial mammillary nucleus, median part 74-75, 141-142

6-7, 10-11

MasM masseter muscle 1-14, 42-47, 49-50, 54-61, 63-65, 69-72, 95-96

MnPO median preoptic nucleus 11, 58, 120-122

masn masseteric nerve 68-70, 74

MO medial orbital cortex 48-49, 105-108

masv

MB mammillary body 22

MoCb molecular layer of the cerebellum 154-156, 161-162, 166-176

Mc Meckel’s cartilage 1, 3, 5-19, 65-76

MoDG molecular layer of the dentate gyrus 126-145

mcer middle cerebral artery 5-7, 63, 123-128

mp

MCLH magnocellular nucleus of the lateral hypothalamus 69, 71-73, 132-135

MPA medial preoptic area 7, 58-64, 120-126

mcp

masseteric vein

72

middle cerebellar peduncle 85-92, 147-155

25, 29-38, 78-83,

MDC mediodorsal thalamic nucleus, central part 68, 131-133 MdD medullary reticular nucleus, dorsal part 37-38, 41, 100-103, 170-176 MDL mediodorsal thalamic nucleus, lateral part 66-69, 130-135

medial preoptic nucleus

12

MPOC medial preoptic nucleus, central part 62, 124 MPOL medial preoptic nucleus, lateral part 59-64, 122-127 MPOM medial preoptic nucleus, medial part 60-64, 124-127 MPT medial pretectal nucleus 24-25, 73-74, 139-142 MPtA

medial parietal association cortex

70, 129-131

MPtg medial pterygoid muscle 11-14, 64-74

MDM mediodorsal thalamic nucleus, medial part 66-67, 69, 130-136 MdV medullary reticular nucleus, ventral part 35-36, 100-103, 170-176

MRe mammillary recess of the 3rd ventricle 25, 140-142 MRec medial rectus muscle 110, 112

ME median eminence 22, 134

3-7, 49, 54-55, 104, 108,

mRt mesencephalic reticular formation 150 16-20

mesencephalic trigeminal nucleus 155, 160-161

MS medial septal nucleus 5-10, 53-58, 114-120 34-35, 91-92,

MT medial terminal nucleus of the accessory optic tract 77, 144-145

medial amygdaloid nucleus, anterior part 14-15

MeAD medial amygdaloid nucleus, ant dorsal 128-133

66-70,

MeAV medial amygdaloid nucleus, anteroventral part 17, 67-70, 130-132 medial (fastigial) cerebellar nucleus 162-167

MSO medial superior olive 86, 154-157 Mst mastoid process of temporal bone 28

me5 mesencephalic trigeminal tract 34, 36, 91

Med

MPB medial parabrachial nucleus 31-32, 34-35, 86-92, 156-157, 159-161

MPO

MD mediodorsal thalamic nucleus 16-22, 64-65, 126-129

MeA

24-25, 143-144, 146-147

MPL medial paralemniscial nucleus 28-31, 80-85, 148-154

MCPO magnocellular preoptic nucleus 11-13, 58-66, 119-130

Me5

mammillary peduncle

MPBE medial parabrachial nucleus external part 158

MCPC magnocellular nucleus of the posterior commissure 26, 73-75, 140-144

Me medial amygdaloid nucleus

MnR median raphe nucleus 26-30, 79-85, 150-155

39, 94-99,

MedDL medial cerebellar nucleus, dorsolateral protuberance 165-167 MedL medial cerebellar nucleus, lateral part 164-165 MEE medial eminence, external layer 18, 74-76, 135-138 MEI medial eminence, internal layer 18, 74-76, 135-138 MEnt medial entorhinal cortex 81-82, 145-150 MePD medial amygdaloid nucleus, posterodorsal part 70-73, 133-137

mt

mammillothalamic tract 23, 65-74, 127-139

mtg

mammillotegmental tract 24-31, 73-76, 140-147

MTu medial tuberal nucleus 16-21, 70-74, 133-140 MVe medial vestibular nucleus 28-38, 95-99, 166-168 MVeMC medial vestibular nucleus, magnocellular part 88-94, 159, 161-165 MVePC medial vestibular nucleus, parvicellular part 88-94, 159-165 MVPO medioventral periolivary nucleus 22, 81-86, 151-157 Mx matrix region of the medulla 94-95, 97-103, 165-176 mxa MxB

maxillary artery

70

maxillary bone (maxilla) 104

1-7, 9, 42-47, 55-56,

MePV medial amygdaloid nucleus, posteroventral part 71-73, 133-134, 137

mxv

mfb medial forebrain bundle 17-25, 56, 112, 116-118, 132-133, 137-139

MZMG marginal zone of the medial geniculate 142

maxillary vein

14, 73

MyHy mylohyoid muscle 1, 3, 5-9

MG medial geniculate nucleus 25-30, 74 MGD medial geniculate nucleus, dorsal part 75-78, 140-145

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

N NasC nasal cavity 1-17, 42-52, 54-58, 60-63, 65-69, 72-75, 78, 104-105, 108, 110, 112, 116, 121 ne neuroepithelium 1-10, 26, 28-29, 42-58, 60, 62-65, 67-69, 75-76, 79-80, 85-87, 92-98, 104-132, 134-137, 156, 158 ns

nigrostriatal bundle

NSpt Nv

nasal septum

124, 132-133, 137-139, 141

1-7, 42-50, 52, 104-105, 108, 110

navicular nucleus of the basal forebrain 111-113

50-52,

pc posterior commissure 24, 26, 73-74, 138-144

POHy

pcer posterior cerebral artery 20, 24-26, 76-77, 148

PoMn posteromedian thalamic nucleus 70, 136

RChL retrochiasmatic area, lateral part 131-133

PCom nucleus of the posterior commissure 75-76, 141-144

Post postsubiculum 73-81, 142-150

RCPMj rectus capitis posterior major muscle 35-41

PoT posterior thalamic nuclear group, triangular part 26, 75-78, 142-145

Re reuniens thalamic nucleus 15-18, 63-68, 124-134

PP peripeduncular nucleus 75, 142-143

REth retroethmoid nucleus 25, 74, 142

PCRtA parvicellular reticular nucleus, alpha part 26-28, 88-91, 158-161

ppf

rf

pcuf preculminate fissure 161

PPT posterior pretectal nucleus 25-26, 75-76, 142-143

PCRt parvicellular reticular nucleus 26-29, 31-33, 35-36, 87, 92-99, 162-169

PDig posterior belly of the digastric muscle 20-21 PDPO posterodorsal preoptic nucleus 123-124

O

PDR

ocb

olivocochlear bundle

159

Occ

occipital bone

29-37, 39-41, 97-100, 167

occ

occipital artery

92-93, 95-97

occs

occipital sinus

och

optic chiasm

30, 32-38, 99-100 10-13, 64-65, 125-127

27,

posterodorsal raphe nucleus

61-62,

preoptic hypothalamus

prepyramidal fissure

8-11

168-174

PDTg posterodorsal tegmental nucleus 160-161

89-91,

Pr prepositus nucleus 31-35, 89-96, 160-167 Pr5

principal sensory trigeminal nucleus 23-26, 28-29, 83-85, 87-89, 151-154, 159-160

RL retrolemniscal nucleus 148, 157-158

20-21, 70-73, 133-137

RLi

Op optic nerve layer of the superior colliculus 76-87, 143-159

PFl

PrEW pre-Edinger-Westphal nucleus 145-147

OPC oval paracentral thalamic nucleus 69-70, 135-136

pfs

4-6, 51

opha ophthalmic artery 9 ophv ophthalmic vein

4-7, 46, 112

OPT olivary pretectal nucleus 23-27, 72-75, 139-143 opt

optic tract 140-141

12-21, 24, 66-71, 74-75, 128-137,

paraflocculus

PFlCv

91-102, 154-167

parafloccular cavity

parafloccular sulcus

92, 94-95, 167

96-101, 156-167

PRh perirhinal cortex 70-82, 133-152

PHA posterior hypothalamic area 25-26, 72-74, 139-142

PrLSp pre lateral spinal 100, 170-175

PHD posterior hypothalamic area, dorsal part 69, 71, 134-136

Or oriens layer of the hippocampus 63, 127-142

PIF parainterfascicular nucleus of the VTA 28-29, 77-79, 146-149

OV

otic ganglion

16-17, 72-73

olfactory ventricle (olfactory part of lateral ventricle) 1-2, 42-50, 104-111

posterior intralaminar thalamic nucleus 74-78, 141-145

26,

Pinna pinna of the ear 28, 30-31 Pir piriform cortex 3-21, 49-64, 67, 71

OvalW oval window 23, 25, 72, 84

Pir1 piriform cortex, layer 1 65-66, 68-70, 72-75, 108-139

P

Pk

P5 peritrigeminal zone 84-86, 153-155, 157 P7

perifacial zone

23, 25-26, 87, 158, 160-162, 164

Pa paraventricular hypoth nucleus 14-18

Purkinje cell layer of the cerebellum 161-163, 166-176

154-156,

PLCo posterolateral cortical amygdaloid nucleus 18-20, 70-75, 134-140

Pa4 paratrochlear nucleus 35, 84-85, 150, 153-154

PLCo1 posterolateral cortical amygdaloid nucleus, layer 1 133

Pa5 paratrigeminal nucleus 98, 100, 168-170

PLd

PaAP paraventricular hypothalamic nucleus, anterior parvicellular part 13, 61-63, 124-126

plf posterolateral fissure 91-97, 155-166

PaC

paracommissural nucleus of the posterior commissure 74, 143-144

PaDC paraventricular hypothalamic nucleus, dorsal cap 68, 130-131 PAG periaqueductal gray 26-38, 72, 74, 93-97, 139-144 Pal palatine bone

5-11, 48-52, 55-61, 64-65

paralambdoid septal nucleus

56-57

PLH peduncular part of lateral hypothalamus 13-26, 65-68, 70-74, 76, 127-132, 136-143 PLi posterior limitans thalamic nucleus 73-76, 141-145 PlPAG pleoglial periaqueductal gray 149-152 PLV

77-78, 143-147,

perilemniscal nucleus, ventral part 151

PM paramedian lobule 102-103, 163-172

PalGl palatoglossus muscle 14

pm principal mammillary tract 24, 140-143

PaLM paraventricular hypothalamic nucleus, lateral magnocellular part 65-67, 128-130

PMCo posteromedial cortical amygdaloid nucleus 19-20, 71-76, 78-80, 133-143

PaMM paraventricular hypothalamic nucleus, medial magnocellular part 64-65, 127 PaMP paraventricular hypothalamic nucleus, medial parvicellular part 64-68, 127-131 PaPo paraventricular hypothalamic nucleus, posterior part 18, 68, 131

16-23, 26-28, 30, 78-81, 85-86,

PSol parasolitary nucleus 98-100, 168-171 PSph presphenoid bone 7-13, 15-16, 54-64, 112-118, 121 PSphW presphenoid wing 2-16, 53-57, 109, 116 PSTh parasubthalamic nucleus 22, 25, 71-76, 136-140 PT paratenial thalamic nucleus 14-15, 62-64, 123-129 18, 99-100

Ptg

pterygoid process of the sphenoid bone 66-69, 71

11-15,

retrosplenial dysgranular cortex 127-152

22-26, 63-82,

RSG retrosplenial granular cortex 22-26, 148-149 RSGa retrosplenial granular cortex, a region 71-82, 138-147 RSGb retrosplenial granular cortex, b region 69-80, 132-145 RSGc retrosplenial granular cortex, c region 63-78, 127-141

reticluostrial nucleus

17, 63-67, 124-130

RtTg reticulotegmental nucleus of the pons 25, 79-83, 150-157

RtTgP reticulotegmental nucleus of the pons, pericentral part 156

PtPC parietal cortex, posterior area, caudal part 136-139

RVL rostroventrolateral reticular nucleus 163, 165

PtPD parietal cortex, posterior area, dorsal part 132, 134-136 PtPR parietal cortex, posterior area, rostral part 132-135

RVRG rostral ventral respiratory group 97-98, 100, 167-172

S S1BF primary somatosensory cortex, barrel field 62-70, 123-132

PMnR paramedian raphe nucleus 26-32, 34, 80-85, 150-155

PVP

S1DZ primary somatosensory cortex, dysgranular zone 55-70, 113-130

pms paramedian sulcus 100-101, 170-172

paraventricular thalamic nucleus, posterior part 19-20, 69-70, 133-137

Py pyramidal cell layer of the hippocampus 126-142 py

pyramidal tract 153-176

25, 28-31, 82-86, 88-96, 99-101,

86, 156-157

primary somatosensory cortex, forelimb region 55-56, 58-65, 113-126

S1HL primary somatosensory cortex, hindlimb region 57, 62-68, 121-128

R Rad radiatum layer of the hippocampus 126-142

PnV pontine reticular nucleus, ventral part 85, 156-157

RAPir Rath

Rathke’s pouch

Po posterior thalamic nuclear group 18-25, 27-28, 68-77, 132-145

Rbd

rhabdoid nucleus

PoDG polymorph layer of the dentate gyrus 128-144

RCh

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

S1DZO primary somatosensory cortex, oral dysgranular zone 59, 117-119 S1FL

Pn pontine nuclei 24-25, 27, 77-81, 146-153

pontine raphe nucleus

S1 primary somatosensory cortex 71, 133-134

pyx pyramidal decussation 35-36, 102-103, 176

RAmb retroambiguus nucleus 100-102, 172-175

PC paracentral thalamic nucleus 23, 63-64, 67-69, 127-131, 133-134

RSD

ptgpal pterygopalatine nerve 13, 58-59, 61-65, 67-68, 70-85, 87, 121, 146-147, 150-152

PnR

parabrachial pigmented nucleus of the VTA 27-31, 74-80, 141-149

rs rubrospinal tract 24-25, 34, 83, 85-86, 88, 93-95, 97, 99, 101-103, 149-176

RtTgL reticulotegmental nucleus of the pons, lateral part 84, 157

PaXi paraxiphoid nucleus of thalamus 126-133

PBP

RRF/A8 retrorubral field and A8 dopamine cells 34, 150-152

ptgcn nerve of the pterygoid canal 14, 77, 121

R red nucleus 30, 32, 75-76

PBG parabigeminal nucleus 34, 82-87, 150-155

RRF retrorubral field 32-33, 80-82, 149

RtSt

PnO pontine reticular nucleus, oral part 24-32, 79-83, 85-86, 148-155

36

32-33, 81-82, 151-153 20-24, 69, 135-136

PTg pedunculopontine tegmental nucleus 32-34, 81-86, 150-157

PaV paraventricular hypothalamic nucleus, ventral part 64-67, 127-130

parabrachial nucleus

retrouniens area

Rt reticular thalamic nucleus 14-19, 28-32, 63-69, 73-76, 78-80, 124-134, 140, 142-149, 151-153

PaS parasubiculum 25, 81-82, 144-152

PB

retrorubral nucleus

RRe

PTe paraterete nucleus 68, 131-136

PnC pontine reticular nucleus, caudal part 24-26, 82-86, 154-158

15, 18, 63-68,

RR

PMn paramedian reticular nucleus 165

PN paranigral nucleus of the VTA 79, 146-148

parietal plate 92-93, 95, 97

psf posterior superior fissure 155, 157, 159-163, 165-169

RPF retroparafascicular nucleus 26, 73, 141

PVA paraventricular thalamic nucleus, anterior part 14-16, 62-65, 123-129

ParB ParP

PSCCA posterior semicircular canal ampulla 29

RPC red nucleus, parvicellular part 26-29, 77-78, 144-147

S subiculum 21-22, 24, 77-80

PMD premammillary nucleus, dorsal part 73-76, 139-141

PMV premammillary nucleus, ventral part 74-76, 139-140

31, 33-36, 38

PSCC posterior semicircular canal 29-34, 95-97, 99

parotid gland

RMg raphe magnus nucleus 24-28, 85-92, 156-164

PV paraventricular thalamic nucleus 17, 21, 66-68, 71, 130-132

PaR pararubral nucleus 30, 32-33, 36, 78-81, 147-149 parietal bone

PrTh prethalamus (prosomere 3) 15-18, 20-21, 25-26

Ptd

RMC red nucleus, magnocellular part 31, 33, 77-81, 145-149

RPa raphe pallidus nucleus 22-30, 32-35, 85-98, 100, 156-167, 170-174

PrS presubiculum 25, 27, 75-81, 86, 145-149

71-75, 77

27-32, 76,

ROb raphe obscurus nucleus 30-34, 36, 93-98, 100, 163-169, 171-174

PrL prelimbic cortex 48-53, 106-114

Pt parietal cortex

rostral linear nucleus of the raphe 78-80, 143-147

Ro nucleus of Roller 35, 95-98, 165-169, 172

psa posterior superior alveolar artery 1, 3

Pig pigment layer of the eye 2-9, 42-44, 54-55, 104-105, 108-110, 112-114 PIL

27, 76-78,

PS parastrial nucleus 59-60, 121-122

pica posteroinferior cerebellar artery 33, 35

Otic

PrCnF precuneiform area 34, 81-82, 84-85, 150-155

prf primary fissure 162-165

OptF optic foramen 8, 55-56, 112-116

OT nucleus of the optic tract 23, 25-28, 74-76, 140-143

PrBo pre-Botzinger complex 95-96, 166

PH posterior hypothalamic nucleus 22-24, 70-73, 136-141

Pi pineal gland 24, 26-27, 75-77, 144-148

Oral oral cavity 1-14, 17, 43-49, 52, 54-58, 60-63, 65-68, 71, 78, 80-85

RI rostral interstitial nucleus of medial longitudinal fasciculus 25-26, 72, 140-142

Pr5VL principal sensory trigeminal nucleus, ventrolateral part 155-158

perifornical nucleus

PrC precommissural nucleus 23-24, 71-73, 138-141

optic disc

Rh rhomboid thalamic nucleus 16-17, 65-68, 127-134

PeF

PF parafascicular thalamic nucleus 22-25, 70-72, 136-140

OpD

2-4, 6-7,

RIP raphe interpositus nucleus 23-24, 82-89, 154-159

OmHy omohyoid muscle 24 1-2, 42-43, 46, 104-106

retinal ganglion cell layer of the retina 43-46, 49-53, 104-105, 108-110

Pr5DM principal sensory trigeminal nucleus, dorsomedial part 155-158

PeFLH perifornical part of lateral hypothalamus 68-73, 132-138

olfactory nerve layer

RGn

Pe periventricular hypothalamic nucleus 61-69, 73, 122-132, 134-138

OF optic fiber layer of the retina 2-7, 43-46, 49-53, 104-105, 108-110 ON

rhinal fissure 6-7, 20, 22, 52-53, 55-58, 60-66, 68-75, 77-78, 82, 108, 110, 111-121, 125-129, 131136, 141-148

162-163

PR prerubral field 22-25, 70-74, 137-143

85-86, 152-154

ReIC recess of the inferior colliculus 160-161

PPit posterior lobe of pituitary 18-19, 77-78, 143

PPy parapyramidal nucleus

68-69,

rostral amygdalopiriform area

71-73, 135-137

19 84, 152-153

Rc Reichert’s cartilage 22-24, 92 retrochiasmatic area

15, 68, 70, 131

S1J

primary somatosensory cortex, jaw region 51-59, 109-119

S1Sh

primary somatosensory cortex, shoulder region 66-67, 127-129

S1Tr

primary somatosensory cortex, trunk region 68-70, 129

S1ULp primary somatosensory cortex, upper lip region 59-62, 66-69, 117-130 S2 secondary somatosensory cortex 60, 63-70, 113-132

XXI

s5

sensory root of the trigeminal nerve 78-79, 81-83, 143, 146-154

19, 76,

S9Gn superior ganglion of the glossopharyngeal nerve 93-97, 162-163, 167 Sacc

saccule

Sag

SOR supraoptic nucleus, retrochiasmatic part 14

Su5

sox supraoptic decussation 12-19, 64-69, 71, 128-137, 139

Sub submedius thalamic nucleus 66-69, 129, 131-134

sp5

SubB subbrachial nucleus 144-151

23-26

sagulum nucleus

86, 89-92, 156

spinal trigeminal tract 94-103, 152, 155-176

27-35, 37-41, 84-92,

supratrigeminal nucleus

30-31, 85-88, 155-158

27-28, 30-32, 76-82,

V1B primary visual cortex, binocular area 138-140, 143, 145-147 V1M primary visual cortex, monocular area 138-140, 143, 146-147 V2L secondary visual cortex, lateral area 71-82, 133-152

Sp5C spinal trigeminal nucleus, caudal part 37-41, 96-103, 171-176

SubC subcoeruleus nucleus 27, 29, 33, 88

Sp5I spinal trigeminal nucleus, interpolar part 27-36, 91-101, 161-173

SubCD subcoeruleus nucleus, dorsal part 26, 28, 85, 87, 154-158

scc splenium of the corpus callosum 66, 135

Sp5O spinal trigeminal nucleus, oral part 23-29, 89-90, 161-163

SubCV subcoeruleus nucleus, ventral part 28, 85, 155-156

SCh suprachiasmatic nucleus 11-14, 64-65, 67-68, 126-127

SPa subparaventricular zone of the hypothalamus 64-68, 127-131

SubG subgeniculate nucleus 134-141

SChDL suprachiasmatic nucleus, dorsolateral part 66, 128-130

SPF subparafascicular thalamic nucleus 22, 70-71, 137-139

SubI

subincertal nucleus

SubP

subpostrema area

SChVM suprachiasmatic nucleus, ventromedial part 66, 127-130

SPFPC subparafascicular thalamic nucleus, parvicellular part 138-143

SubV submedius thalamic nucleus, ventral part 3, 23-25, 28

VCCap ventral cochlear nucleus, capsular part 160-162

SCM superior constrictor muscle of the pharynx 82

Sph

SCO subcommissural organ 72-74, 138-141

SubVCx subventricular layer of developing cortex 4-9, 11-22, 26-27

VCl ventral part of claustrum 60-66, 68, 110-132

SphPal sphenopalatine ganglion 4-11, 13, 52-59, 61-64, 110, 112

SalPh

salpingopharyngeus muscle

20-21

SC superior colliculus 27-41, 75, 88-98, 142 Sc scaphoid thalamic nucleus 73, 140-141 Scap scapula 24, 34, 37

sphenoid nucleus

90-92, 160-161

SubCA subcoeruleus nucleus, alpha part 87, 157-158

20-21, 29, 70-72,

V2ML secondary visual cortex, mediolateral area 71-82, 132-147 V2MM secondary visual cortex, mediomedial area 71-82, 132-150 VA ventral anterior thalamic nucleus VC ventral cochlear nucleus

vc ventral column of the spinal cord 33-34 VCA

69-70, 134 168-170, 172-173

VCP

ventral cochlear nucleus, anterior part 26-29, 86-91, 153-158

ventral cochlear nucleus, posterior part 91-94, 159-162, 164

SplCa splenius capitis muscle 34-41

SuG superficial gray layer of the superior colliculus 76-81, 143-160

SPO superior paraolivary nucleus 85-86, 155-157

SuM supramammillary nucleus 23-25

ScTy scala tympani 80-87, 89-91, 153-154

Spt

sf secondary fissure 152, 169-175

SPTg subpeduncular tegmental nucleus 33, 83-84, 152-156

SuML supramammillary nucleus, lateral part 24, 26, 74-76, 140-145

VDB

ScVe scala vestibuli 81-86, 153-154

Sptne septum neuroepithelium 5-10

SuMM supramammillary nucleus, medial part 74-76, 140-145

VeCb

SFi septofimbrial nucleus 58-62, 120-125 SFO subfornical organ 13-14, 62, 123-126

SpVe spinal vestibular nucleus 29-39, 92-98, 161-168

SG

SRec superior rectus muscle 3-8, 49, 51-56, 108-110, 112

scp superior cerebellar peduncle (brachium conjunctivum) 21, 28, 31-37, 76-77, 84, 87-92, 130, 136-137, 145-149, 154-164

suprageniculate thalamic nucleus

SGe

supragenual nucleus

75-78, 142-145

28-30, 88-89, 159-160

SHi septohippocampal nucleus 50-58, 112-116 SHy septohypothalamic nucleus 10-12, 58, 60-61, 119-123

septum

SSp

4

supraspinal nucleus

SuspLig suspensory ligament 104-105

ST bed nucleus of the stria terminalis 10-13

SuVe superior vestibular nucleus 29-36, 88-92, 159-161

st stria terminalis 12-19, 62-73, 121-136

sig sigmoid sinus 99

Stap

Sim simple lobule 91-99, 155-168

StapM stapedius muscle 24-26, 86-87, 89-92

sl sulcus limitans 21, 23, 31, 34, 37-38

STD

84-86

bed nucleus of the stria terminalis, dorsal part 122

Te terete hypothalamic nucleus 70-73, 135-140 TeA

temporal associatin cortex

72-82, 133-148

TempM temporalis muscle 1, 6-14, 16-17, 44-47, 49-50, 54-61, 63-67

Stg stigmoid hypothalamic nucleus 67, 132

sm stria medullaris of the thalamus 14-20, 62-70, 124-134

StHy striohypothalamic nucleus 13, 23, 59-64, 123-126

TempP temporal bone, petrosal part 22-23, 25-26, 28-36, 78-79, 81-82, 84, 87, 89, 92, 100, 151-152, 154, 163, 167

SMT submammillothalamic nucleus 71, 73, 138

STI bed nucleus of the stria terminalis, intermediate division 121-122

TempS temporal bone, squamous part 13-21, 66-73

SMV

superior medullary velum

162

SN substantia nigra 26-33 SNCD substantia nigra, compact part, dorsal tier 74-80, 140-149 SNCM substantia nigra, compact part, medial tier 76, 78-79, 146-147, 149 SNCV substantia nigra, compacta part, ventral tier 77, 79, 145, 149 SNL substantia nigra, lateral part 76-77, 79, 142-146, 148 SNR SO

substantia nigra, reticular part 139-149 supraoptic nucleus

74-76, 78-80,

14-16, 65-69, 127-131

SOb superior oblique muscle 2-4, 6, 46, 104, 109 SObCa superior oblique capitis muscle 30-31, 33-34 SOl

superior olivary nucleus. lateral part 23

Sol nucleus of the solitary tract 30-41, 89-103 sol

solitary tract 30-32, 34-35, 37-38, 40-41, 95-103, 162-167, 170-174

SolC nucleus of the solitary tract, commissural part 171-176 SolCe nucleus of the solitary tract, central part 168-170 SolDL solitary nucleus, dorsolateral part 163, 167-173 SolDM nucleus of the solitary tract, dorsomedial part 164-166 SolG nucleus of the solitary tract, gelatinous part 168-170 SolIM nucleus of the solitary tract, intermediate part 162-174 SolL nucleus of the solitary tract, lateral part 167, 174 SolM nucleus of the solitary tract, medial part 162-176 SolRL nucleus of the solitary tract, rostrolateral part 162-163 SolV solitary nucleus, ventral part 164-174 SolVL nucleus of the solitary tract, ventrolateral part 93, 164-173

XXII

STIA bed nucleus of the stria terminalis, intraamygdaloid division 19-20, 69-73, 132-136

vestibulocerebellar nucleus

31, 93, 161-164

VeGn vestibular nerve ganglion 25-26, 28, 83-87, 151-155, 157 VEn

ventral endopiriform nucleus 132

65-70, 127-130,

Vent ventricular space of the eye 2-7, 42-46, 51-52, 54, 104-105, 108-110, 112-113 vert vertebral artery 33, 100-102, 172-174 vesp

vestibulospinal tract

161

VG ventral geniculate nucleus 18-25, 69-74, 131-134, 136-141

T

SM nucleus of the stria medullaris 14-15, 63-64, 126-129

STh subthalamic nucleus 21-24, 70-74, 135-139

nucleus of the vertical limb of the diagonal band 52-57, 114-118

Vest vestibule of the inner ear 84-87

StA strial part of the preoptic area 59-60, 121-122 stapedius bone

27,

VCPO ventral cochlear nucleus, posterior part, octopus cell area 163

SupM superior meatus 44

sss superior sagittal sinus 75-79

SIB substantia innominata, basal part 54-64, 116-127

SLu stratum lucidum of the hippocampus 126-142

sumx supramammillary decussation 25-26, 74, 142-143 SuS superior salivatory nucleus 88-89, 158-159

103

65, 128-130

30-31

tfp transverse fibers of the pons 24, 26, 28-29, 77-81, 147-152

ventral geniculate nucleus, layer 1

135

VH ventral horn of spinal cord 33-36 vhc ventral hippocampal commissure 62-63, 122-126 VIEnt ventral intermediate entorhinal cortex 81, 145-147 Vitr vitreous cavity (posterior chamber) of the eye 2-3, 6, 44, 52 VL ventrolateral thalamic nucleus 16-17, 65-67, 128-132

TG

tectal gray

STLD bed nucleus of the stria terminalis, lateral division, dorsal part 59-60, 120-121

Thy

thyroid gland

STLI bed nucleus of the stria terminalis, lateral division, intermediate part 61, 122-123

TMJ temporomandibular joint 16-18, 67, 69-73

VLi ventral linear nucleus of the thalamus 139-140

Tongue tongue 1-14

VLL

STLJ bed nucleus of the stria terminalis, lateral division, juxtacapsular part 59-60, 121-122 STLP bed nucleus of the stria terminalis, lateral division, posterior part 59-62, 120-124 STLV bed nucleus of the stria terminalis, lateral division, ventral part 59-60, 121-123 StM sternomastoid muscle 20-21, 23-24, 26, 92-97 STMA bed nucleus of the stria terminalis, medial division, anterior part 58-60, 119-120

27-28, 73-76, 142-145

VG1

TPal tensor palati muscle 14-15, 71-72, 74-75 TrLL triangular nucleus, lateral lemniscus 153-154 trs transverse sinus 30, 32-36, 75-81, 85-87, 91-93, 97

TT tensor tympani muscle 77-82 trigeminothalamic tract

STMAM bed nucleus of the stria terminalis, medial division, anteromedial part 121-122

Tu1

STMV bed nucleus of the stria terminalis, medial division, ventral part 59-60, 121-122

148, 150-151

4-12, 50-52, 54-63, 111, 125

olfactory tubercle, layer 1

112-124

TuLH tuberal region of lateral hypothalamus 67, 70-71, 130-132, 137-140 ty9

tympanic branch of the glossopharyngeal nerve 91-94

TyBu

tympanic bulla

TyC

tympanic cavity

18-25, 82, 84-85, 87, 89-90 18, 20-24, 79, 90

StyGl styloglossus muscle 10-12, 14, 16, 20-21 StyMF

stylomastoidforamen

StyPh

stylopharyngeus muscle

Su3 supraoculomotor periaqueductal gray 32-34, 80-82, 149-150 Su3C supraoculomotor cap 32, 34, 80-82, 149

VMHC ventromedial hypothalamic nucleus, central part 70, 133-136 VMHDM ventromedial hypothalamic nucleus, dorsomedial part 69-72, 133-136 VMHSh ventromedial nucleus of the hypothalamus shell 68, 73, 131-136 VMHVL ventromedial hypothalamic nucleus, ventrolateral part 69-72, 133-136 vmnf ventral median fissure 103 VMPO ventromedial preoptic nucleus 21, 58-64, 122-126 vn vomeronasal nerve 105 VO ventral orbital cortex 48-49, 105-109

tz

trapezoid body

23, 28, 92, 153-162

VOLT vascular organ of the lamina terminalis 6-10, 58, 119-122

TzM trapezius muscle 28-31, 33-37, 39-41

Vom

tzx

VP

ventral pallidum

VPL

ventral posterolateral thalamic nucleus 66-67, 69-71, 130-138

decussation of the trapezoid body

22

U

vomer

1-5, 42-43 11-12, 52-64, 112-127 17-24,

VPM ventral posteromedial thalamic nucleus 18-25, 68-73, 131-141 VPPC ventral posterior nucleus of the thalamus, parvicellular part 22-24, 69-71, 135-139

90 20-21

59-64, 122-126

Tz nucleus of the trapezoid body 22-23, 82-85, 153-157

Utr utricle 26, 28, 84, 87, 89-90, 92-94

StyHy stylohyoid muscle 20-21

ventrolateral preoptic nucleus

TyM tympanic membrane 18

str superior thalamic radiation 69-70, 135, 137-141 stv superficial temporal vein 3-4, 6-11

VLPO

VMH ventromedial hypothalamic nucleus 15-21, 73-74, 131-132, 137-138

tectospinal tract 32, 83-84, 150-155, 161-176

TSne triangular septal nucleus, neuroepithelial zone 13

olfactory tubercle

STMPM bed nucleus of the stria terminalis, medial division, posteromedial part 61-62, 123-124

VLPAG ventrolateral periaqueductal gray 81-92, 150-151, 156-159

ts

Tu

STMPL bed nucleus of the stria terminalis, medial division, posterolateral part 61-63, 123-124

21-28,

VM ventromedial thalamic nucleus 65-69, 129-136

tth

STMPI bed nucleus of the stria terminalis, medial division, posterointermediate part 61-62, 123-124

ventral nucleus of the lat lemniscus 78-83, 148-153

TS triangular septal nucleus 12, 60-62, 121-125

STMAL bed nucleus of the stria terminalis, medial division, anterolateral part 121-122

STMP bed nucleus of the stria terminalis, medial division, posterior part 63-64, 123, 125-127

VLH ventrolateral hypothalamic nucleus 65-67, 127-130

17, 21

V v vein 146 V1 primary visual cortex 71-82, 133-137, 141-142, 144, 148, 150-152

VRe ventral reuniens thalamic nucleus 64-65, 67, 125-134 VS ventral subiculum 75-77, 140-148

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

vsc

ventral spinocerebellar tract 30-32, 84, 86-87, 152-176

VTA ventral tegmental area 30-32 VTAR ventral tegmental area, rostral part 27, 29, 74-76, 143-145 VTg ventral tegmental nucleus 33-34, 86-88, 154-157 vtgx ventral tegmental decussation 80, 146, 148 VTM ventral tuberomammillary nucleus 22, 75-76, 140-144 VTT

ventral tenia tecta

48-49, 108, 110

VTT1 ventral tenia tecta, layer 1 109

X X nucleus X 32, 34-35, 92-96, 161-166 Xi xiphoid thalamic nucleus 64-68, 126-133 xscp decussation of the superior cerebellar peduncle 33, 81-83, 149-153

Y Y nucleus Y 93-94, 161-163

Z Z

nucleus Z

96, 167

ZIC zona incerta, caudal part 74-75, 140-143 ZID zona incerta, dorsal part 18-25, 69-73, 134-140 ZIR zona incerta, rostral part 65-68, 72, 127-133 ZIV zona incerta, ventral part 18-25, 68-71, 73-74, 134-141 ZL zona limitans 58 Zo zona layer of the superior colliculus 76-81, 143-160 ZygA zygomatic arch 1-14, 45-47, 49-51, 54-61, 63-67

Atlas of the Developing Mouse Brain at E17.5, P0, and P6 Paxinos Halliday Watson Koutcherov Wang

XXIII

This page intentionally left blank

Figures E17.5 Figures 1-42 P0 Figures 43-103 P6 Figures 104-176

Figure 1 E17.5 #1 0.24 mm

Mi ne OV

Gl EPl

Gr

IPl

ON 1n

CrP MidM NasC EthB NSpt Vom

InfM 5mx iorb

TempM

NasC MxB

ZygA dpal

EnO

Oral psa MasM Tongue EnO Man ialn Mc

Man

GeGl

MyHy ADig

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division ADig anterior digastric muscle CrP cribriform plate ethmoid dpal descending palatine artery EnO enamel organ EPl ext plexiform layer olf bulb EthB ethmoid bone GeGl genioglossus muscle Gl glomerular layer olf bulb Gr gracile nu ialn inferior alveolar nerve InfM inferior meatus iorb infraorbital artery IPl IP layer olf bulb Man mandible MasM masseter muscle Mc Meckel’s cartilage Mi mitral cell layer olf bulb MidM middle meatus MxB maxillary bone MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum ON olfactory nerve layer Oral oral cavity OV olfactory ventricle psa post sup alveolar artery TempM temporalis muscle Tongue tongue Vom vomer ZygA zygomatic arch

Figure 2 E17.5 #2 0.48 mm

AOB

IPl

dlo Gl

OV

EPl

ne

lo Fro

Mi

ON

GrO

Eyelid

1n

AOE SOb

Vent Cornea AntCh

PSphW

CrP MidM

NasC

ne

Lens

Vitr OF RGn InPl

NSpt

5mx

EthB

Vom

iorb

NasC

Pig

MxB dpal

EnO ZygA

Oral MasM Tongue

EnO Man

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division AntCh anterior chamber AOB access olfactory bulb AOE ant olfactory nu, ext Cornea cornea CrP cribriform plate ethmoid dlo dorsal lat olfactory tract dpal descending palatine artery EnO enamel organ EPl ext plexiform layer olf bulb EthB ethmoid bone Eyelid eyelid Fro frontal bone Gl glomerular layer olf bulb GrO granular cell layer olf bulb InPl inner plexiform layer iorb infraorbital artery IPl IP layer olf bulb Lens lens lo lateral olfactory tract Man mandible MasM masseter muscle Mi mitral cell layer olf bulb MidM middle meatus MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer ON olfactory nerve layer Oral oral cavity OV olfactory ventricle Pig pigment layer of the eye PSphW presphenoid wing RGn ganglion cell layer SOb superior oblique muscle Tongue tongue Vent ventricular space eye Vitr vitreous cavity eye Vom vomer ZygA zygomatic arch

Figure 3 E17.5 #3 0.60 mm

1Cx CxP SubV Cxne LV lo

Fro

ne

Pir

Eyelid

Vent

AO 1n

SOb

PSphW MidM

ne

Cornea Lens

CrP NasC

SRec Vitr

OF RGn

EthB ne Pig

NSpt Vom

psa MRec 5mx iorb

InPl

NasC MxB

EnO

stv

dpal

ZygA

Oral

Tongue MasM

EnO lga Man Mc GeGl MyHy GeHy ADig

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 1n olfactory nerve 5mx 5n, maxillary division ADig anterior digastric muscle AO anterior olfactory nu Cornea cornea CrP cribriform plate ethmoid Cxne neuroepithelial zone cortex CxP cortical plate dpal descending palatine artery EnO enamel organ EthB ethmoid bone Eyelid eyelid Fro frontal bone GeGl genioglossus muscle GeHy geniohyoid muscle InPl inner plexiform layer iorb infraorbital artery Lens lens lga lingual artery lo lateral olfactory tract LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage MidM middle meatus MRec medial rectus muscle MxB maxillary bone MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer Oral oral cavity Pig pigment layer of the eye Pir piriform cortex psa post sup alveolar artery PSphW presphenoid wing RGn ganglion cell layer SOb superior oblique muscle SRec superior rectus muscle stv superficial temporal vein SubV submedius thal nu, ventral Tongue tongue Vent ventricular space eye Vitr vitreous cavity eye Vom vomer ZygA zygomatic arch

Figure 4 E17.5 #4 0.72 mm

1Cx CxP SubVCx ICx Cxne LV

Pir CPune Fro

ne

lo aca

Eyelid

SOb

Acbne Spt

Tu acer

Vent Cornea AntCh

Iris Lens

CrP

PSphW LPS

OF RGn ne Pig InPl SRec OpD

1n NasC

EthB NSpt Vom

MRec ophv

NasC

5mx SphPal EnO

stv

MxB

ZygA Oral MasM

EnO

Tongue

Man

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 1n olfactory nerve 5mx 5n, maxillary division aca anterior commissure, ant Acbne accumbens neuroepithel acer anterior cerebral art AntCh anterior chamber Cornea cornea CPune caudate putamen, neuroep CrP cribriform plate ethmoid Cxne neuroepithelial zone cortex CxP cortical plate EnO enamel organ EthB ethmoid bone Eyelid eyelid Fro frontal bone ICx intermed cortical layer InPl inner plexiform layer Iris iris Lens lens lo lateral olfactory tract LPS levator palpebrae LV lateral ventricle Man mandible MasM masseter muscle MRec medial rectus muscle MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer OpD optic disc ophv ophthalmic vein Oral oral cavity Pig pigment layer of the eye Pir piriform cortex PSphW presphenoid wing RGn ganglion cell layer SOb superior oblique muscle SphPal sphenopalatine ganglion Spt septum SRec superior rectus muscle stv superficial temporal vein SubVCx subventricular layer cortex Tongue tongue Tu olfactory tubercle Vent ventricular space eye Vom vomer ZygA zygomatic arch

Figure 5 E17.5 #5 0.84 mm

1Cx CxP

ICx

SubVCx Cxne LV Sptne

CPune lo

LPS Fro

ec aca BTelne

Pir

LS MS

Eyelid

Tu

Acb

azac

BTel acer

ne

Pig

mcer PSphW EthB ophv

AntCh

Cornea

OF Lens

OpD

2n

NasC

1n

ophv

SRec

NSpt Vom

SphPal MRec 5mx

ophv Vent

ZygA

EnO

NasC Pal MxB Oral

MasM EnO

Tongue

Man ialn MasM

HyGl

Mc

lga

GeGl

MyHy

GeHy

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 1n olfactory nerve 2n optic nerve 5mx 5n, maxillary division aca anterior commissure, ant Acb accumbens nu acer anterior cerebral art AntCh anterior chamber azac azygous ant cerebral art BTel basal telencephalon BTelne basal telenceph, neuroepith Cornea cornea CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule EnO enamel organ EthB ethmoid bone Eyelid eyelid Fro frontal bone GeGl genioglossus muscle GeHy geniohyoid muscle HyGl hyoglossus muscle ialn inferior alveolar nerve ICx intermed cortical layer Lens lens lga lingual artery lo lateral olfactory tract LPS levator palpebrae LS lateral septal nu LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage mcer middle cerebral artery MRec medial rectus muscle MS medial septal nu MxB maxillary bone MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer OpD optic disc ophv ophthalmic vein Oral oral cavity Pal palatine bone Pig pigment layer of the eye Pir piriform cortex PSphW presphenoid wing SphPal sphenopalatine ganglion Sptne septum neuroepithelium SRec superior rectus muscle SubVCx subventricular layer cortex Tongue tongue Tu olfactory tubercle Vent ventricular space eye Vom vomer ZygA zygomatic arch

Figure 6 E17.5 #6 0.96 mm

1Cx CxP SubVCx ICx Cxne LV

lo

Fro

Sptne

CPune

rf

ec

Pir

LS BTelne

aca Eyelid

MS VOLT

Tu

SOb

Acb

Vent

BTel

Iris

acer ne

Cornea Lens

Vitr OpD

RGn

mcer PSphW NasC LPS Pig ophv SRec 2n EthB

ophv

OF

MRec 5mx

InPl

SphPal NasC Pal

EnO

stv

NSpt

MxB

dpal

ZygA

Oral masa

TempM Cor

EnO Tongue

MasM

Man

Mc

lga

MyHy

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 2n optic nerve 5mx 5n, maxillary division aca anterior commissure, ant Acb accumbens nu acer anterior cerebral art BTel basal telencephalon BTelne basal telenceph, neuroepith Cor coronoid process mandible Cornea cornea CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate dpal descending palatine artery ec external capsule EnO enamel organ EthB ethmoid bone Eyelid eyelid Fro frontal bone ICx intermed cortical layer InPl inner plexiform layer Iris iris Lens lens lga lingual artery lo lateral olfactory tract LPS levator palpebrae LS lateral septal nu LV lateral ventricle Man mandible masa masseteric artery MasM masseter muscle Mc Meckel’s cartilage mcer middle cerebral artery MRec medial rectus muscle MS medial septal nu MxB maxillary bone MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer OpD optic disc ophv ophthalmic vein Oral oral cavity Pal palatine bone Pig pigment layer of the eye Pir piriform cortex PSphW presphenoid wing rf rhinal fissure RGn ganglion cell layer SOb superior oblique muscle SphPal sphenopalatine ganglion Sptne septum neuroepithelium SRec superior rectus muscle stv superficial temporal vein SubVCx subventricular layer cortex TempM temporalis muscle Tongue tongue Tu olfactory tubercle Vent ventricular space eye Vitr vitreous cavity eye VOLT vasc organ lam ter ZygA zygomatic arch

Figure 7 E17.5 #7 1.08 mm

1Cx CxP ICx

SubVCx Cxne LV

CPu

rf Fro

ec Pir

lo

CPune Sptne LS

aca Acb

Tu

Eyelid

MS

BTelne

MPA BTel

SRec LPS ne OF RGn

Pig

InPl IRec

Vent

EthB NSpt

LRec

MRec NasC

5mx

stv

EnO ZygA

PSph

PSphW ophv

2n

VOLT

acer

mcer

SphPal Pal MxB

TempM

Oral

masa

EnO

Tongue

Man MasM ialn

Mc MyHy

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

lga

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 2n optic nerve 5mx 5n, maxillary division aca anterior commissure, ant Acb accumbens nu acer anterior cerebral art BTel basal telencephalon BTelne basal telenceph, neuroepith CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule EnO enamel organ EthB ethmoid bone Eyelid eyelid Fro frontal bone ialn inferior alveolar nerve ICx intermed cortical layer InPl inner plexiform layer IRec inferior rectus muscle lga lingual artery lo lateral olfactory tract LPS levator palpebrae LRec lat rectus muscle LS lateral septal nu LV lateral ventricle Man mandible masa masseteric artery MasM masseter muscle Mc Meckel’s cartilage mcer middle cerebral artery MPA medial preoptic area MRec medial rectus muscle MS medial septal nu MxB maxillary bone MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer ophv ophthalmic vein Oral oral cavity Pal palatine bone Pig pigment layer of the eye Pir piriform cortex PSph presphenoid bone PSphW presphenoid wing rf rhinal fissure RGn ganglion cell layer SphPal sphenopalatine ganglion Sptne septum neuroepithelium SRec superior rectus muscle stv superficial temporal vein SubVCx subventricular layer cortex TempM temporalis muscle Tongue tongue Tu olfactory tubercle Vent ventricular space eye VOLT vasc organ lam ter ZygA zygomatic arch

Figure 8 E17.5 #8 1.20 mm

ICx

1Cx

SubVCx CxP Cxne

Ins

ec

Cl

LV

IG

CPune Sptne

CPu Fro

LS

Pir

lo

MS

aca BTelne Acb

Tu

ne BTel ictd

InPl ne Eye

3V POHy

PSphW

SRec

Pig

LRec

iopha

OptF 2n

VOLT

cav

IRec

PSph 5mx

stv

TempM

EnO

NasC

SphPal

Pal

Cor

ZygA

Oral

Man

MasM

Tongue

ialn Mc MyHy

HyGl

lga GeGl

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 2n optic nerve 3V 3rd ventricle 5mx 5n, maxillary division aca anterior commissure, ant Acb accumbens nu BTel basal telencephalon BTelne basal telenceph, neuroepith cav cavernous sinus Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule EnO enamel organ Eye eye Fro frontal bone GeGl genioglossus muscle HyGl hyoglossus muscle ialn inferior alveolar nerve ictd internal carotid artery ICx intermed cortical layer IG indusium griseum InPl inner plexiform layer Ins insular cortex iopha inf ophthalmic artery IRec inferior rectus muscle lga lingual artery lo lateral olfactory tract LRec lat rectus muscle LS lateral septal nu LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage MS medial septal nu MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium OptF optic foramen Oral oral cavity Pal palatine bone Pig pigment layer of the eye Pir piriform cortex POHy preoptic hypothalamus PSph presphenoid bone PSphW presphenoid wing SphPal sphenopalatine ganglion Sptne septum neuroepithelium SRec superior rectus muscle stv superficial temporal vein SubVCx subventricular layer cortex TempM temporalis muscle Tongue tongue Tu olfactory tubercle VOLT vasc organ lam ter ZygA zygomatic arch

Figure 9 E17.5 #9 1.30 mm

1Cx CxP ICx

SubVCx Cxne LV

CPune Ins

CPu ec

Cl

IG

Sptne LS

lo Pir

MS

Fro aca Tu BTel ne

POHy Pig

Eye

PSphW

TempM

3V

ictd

VOLT

opha LRec 4n 3n 6n cav 5oph 5mx MxB

stv

2n PSph

ictd

NasC

SphPal Pal

Cor

ZygA Man ialn MasM

Oral Tongue

Mc MyHy

HyGl

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

lga

0.8

1.0 mm

1Cx layer 1 of developing cortex 2n optic nerve 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve aca anterior commissure, ant BTel basal telencephalon cav cavernous sinus Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule Eye eye Fro frontal bone HyGl hyoglossus muscle ialn inferior alveolar nerve ictd internal carotid artery ICx intermed cortical layer IG indusium griseum Ins insular cortex lga lingual artery lo lateral olfactory tract LRec lat rectus muscle LS lateral septal nu LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage MS medial septal nu MxB maxillary bone MyHy mylohyoid muscle NasC nasal cavity ne neuroepithelium opha ophthalmic art Oral oral cavity Pal palatine bone Pig pigment layer of the eye Pir piriform cortex POHy preoptic hypothalamus PSph presphenoid bone PSphW presphenoid wing SphPal sphenopalatine ganglion Sptne septum neuroepithelium stv superficial temporal vein SubVCx subventricular layer cortex TempM temporalis muscle Tongue tongue Tu olfactory tubercle VOLT vasc organ lam ter ZygA zygomatic arch

Figure 10 E17.5 #10 1.44 mm

1Cx

ICx

Cxne

CxP

IG

Sptne

CPu

LS

Pir

lo

Fro

CPune

ec

Cl

Ins

LV

MS

BTelne ST

aca

SHy

Tu BTel

3V

POHy

ictd PSphW

ne

TempM Cor stv

MasM

ZygA

LPtg

PSph 6n 4n 3n cav SphPal 5oph NasC 5mx Pal ASph

Man

masa

VOLT och

ialn Oral

Mc MasM

Tongue HyGl StyGl lga

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve aca anterior commissure, ant ASph alisphenoid bone BTel basal telencephalon BTelne basal telenceph, neuroepith cav cavernous sinus Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule Fro frontal bone HyGl hyoglossus muscle ialn inferior alveolar nerve ictd internal carotid artery ICx intermed cortical layer IG indusium griseum Ins insular cortex lga lingual artery lo lateral olfactory tract LPtg lat pterygoid muscle LS lateral septal nu LV lateral ventricle Man mandible masa masseteric artery MasM masseter muscle Mc Meckel’s cartilage MS medial septal nu NasC nasal cavity ne neuroepithelium och optic chiasm Oral oral cavity Pal palatine bone Pir piriform cortex POHy preoptic hypothalamus PSph presphenoid bone PSphW presphenoid wing SHy septohypothalamic nu SphPal sphenopalatine ganglion Sptne septum neuroepithelium ST bed nu stria terminalis stv superficial temporal vein StyGl styloglossus muscle TempM temporalis muscle Tongue tongue Tu olfactory tubercle VOLT vasc organ lam ter ZygA zygomatic arch

Figure 11 E17.5 #11 1.56 mm

1Cx

SubVCx CxP ICx Cxne LV

IG CPune fi ec

LS

Ins

CPu

Cl Fro

LTer

BTelne

acp

MnPO

Pir ac ST

VP

SHy

lo MCPO Tu

LPO

HDB POHy

PSphW ictd TempM

3V

ASph 5oph 4n 3n 6n 5mx cav

LPtg

MasM ZygA stv

SCh och SphPal

PSph

NasC

Pal

5man

Ptg

masa Man MasM

Mc

MPtg

Oral

Tongue MasM

StyGl lga HyGl

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5man 5n, mandibular division 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve ac anterior commissure acp anterior comm, posterior ASph alisphenoid bone BTelne basal telenceph, neuroepith cav cavernous sinus Cl claustrum CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule fi fimbria hippocampus Fro frontal bone HDB nu horizlimb diagonal band HyGl hyoglossus muscle ictd internal carotid artery ICx intermed cortical layer IG indusium griseum Ins insular cortex lga lingual artery lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LS lateral septal nu LTer lemina terminalis LV lateral ventricle Man mandible masa masseteric artery MasM masseter muscle Mc Meckel’s cartilage MCPO magnocell preoptic nu MnPO median preoptic nu MPtg medial pterygoid muscle NasC nasal cavity och optic chiasm Oral oral cavity Pal palatine bone Pir piriform cortex POHy preoptic hypothalamus PSph presphenoid bone PSphW presphenoid wing Ptg pterygoid proces sphenoid SCh suprachiasmatic nu SHy septohypothalamic nu SphPal sphenopalatine ganglion ST bed nu stria terminalis stv superficial temporal vein StyGl styloglossus muscle SubVCx subventricular layer cortex TempM temporalis muscle Tongue tongue Tu olfactory tubercle VP ventral pallidum ZygA zygomatic arch

Figure 12 E17.5 #12 1.68 mm

1Cx

CxP

Cxne

LV

ICx SubVCx

chp IG

fi CPune

Ins Cl

CPu

ec

TS ic

Fro

IVF

BTelne

Pir

acp

st VP

f 3V

ST

MCPO

SHy

Tu HDB lo PSphW

LPO AHA MPO ictd LA

TempM

opt ASph

MasM ZygA

Man MasM

och sox PSph

4n 3n

LPtg

SCh

6n 5oph 5mx ASph

Oral

NasC

5man Ptg Mc

MPtg Oral HyGl Tongue StyGl lga

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5man 5n, mandibular division 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve acp anterior comm, posterior AHA anterior hypothal area, ant ASph alisphenoid bone BTelne basal telenceph, neuroepith chp choroid plexus Cl claustrum CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule f fornix fi fimbria hippocampus Fro frontal bone HDB nu horizlimb diagonal band HyGl hyoglossus muscle ic internal capsule ictd internal carotid artery ICx intermed cortical layer IG indusium griseum Ins insular cortex IVF interventricular foramen LA lateroanterior hypothal nu lga lingual artery lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage MCPO magnocell preoptic nu MPO medial preoptic nu MPtg medial pterygoid muscle NasC nasal cavity och optic chiasm opt optic tract Oral oral cavity Pir piriform cortex PSph presphenoid bone PSphW presphenoid wing Ptg pterygoid proces sphenoid SCh suprachiasmatic nu SHy septohypothalamic nu sox supraoptic decussation ST bed nu stria terminalis st stria terminalis StyGl styloglossus muscle SubVCx subventricular layer cortex TempM temporalis muscle Tongue tongue TS triangular septal nu Tu olfactory tubercle VP ventral pallidum ZygA zygomatic arch

Figure 13 E17.5 #13 1.80 mm

1Cx CxP ICx

Cxne

LV chp

SubVCx

fi CPune Ins

IVF

CPu

Cl

TSne

ec GP acp

Pir

ATh BTelne

ic

SFO

st lo

BTel

Fro

ST

3V

MCPO StHy

HDB

Amg

PLH

f

PaAP

PSphW AHA TempS

LA ASph

TempM

LPtg ZygA

opt

ptgpal SphPal 4n 3n 6n 5oph 5mx cav ASph

Man

NasC

Ptg

5man Mc

SCh och sox PSph

MPtg

Oral

MasM

Tongue

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5man 5n, mandibular division 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve acp anterior comm, posterior AHA anterior hypothal area, ant Amg amygdala ASph alisphenoid bone ATh anterior thalamic region BTel basal telencephalon BTelne basal telenceph, neuroepith cav cavernous sinus chp choroid plexus Cl claustrum CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate ec external capsule f fornix fi fimbria hippocampus Fro frontal bone GP globus pallidus HDB nu horizlimb diagonal band ic internal capsule ICx intermed cortical layer Ins insular cortex IVF interventricular foramen LA lateroanterior hypothal nu lo lateral olfactory tract LPtg lat pterygoid muscle LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage MCPO magnocell preoptic nu MPtg medial pterygoid muscle NasC nasal cavity och optic chiasm opt optic tract Oral oral cavity PaAP paraventric hy, ant parvicell Pir piriform cortex PLH peduncular part lat hy PSph presphenoid bone PSphW presphenoid wing Ptg pterygoid proces sphenoid ptgpal pterygopalatine n SCh suprachiasmatic nu SFO subfornical organ sox supraoptic decussation SphPal sphenopalatine ganglion ST bed nu stria terminalis st stria terminalis StHy striohypothalamic nu SubVCx subventricular layer cortex TempM temporalis muscle TempS temporal bone, squamous Tongue tongue TSne triang sept neuropithelial ZygA zygomatic arch

Figure 14 E17.5 #14 1.92 mm

Cg SubVCx 1Cx ICx

LV chp

Cxne

CxP fi

CPune

Hi IVF

Ins

AD BTelne

Cl

Fro

SFO

sm

CPu

ic

acp

st

GP

Pir

PVA

AV PT AM 3V

EA

Rt sm

CxA AA ACo

MeA

SM

Pa

PLH

LOT

f PSphW

opt TempM

LA SOR sox

TempS ASph 4n

ZygA

LPtg

3n 5Gn

Oral 5man

mxv

SCh

6n cav

BSph ptgcn

ASph

NasC

Ptg

Man Mc

HPtg

MPtg TPal

MasM Man

Oral

PalGl

HyGl Tongue

StyGl

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

AH

SO

ictd

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5Gn trigeminal ganglion 5man 5n, mandibular division 6n root of abducens nerve AA anterior amyg area ACo ant cortical amygdaloid nu acp anterior comm, posterior AD anterodorsal thalamic nu AH anterior hypothalamic area AM anteromedial thalamic nu ASph alisphenoid bone AV anteroventral thalamic nu BSph basisphenoid bone BTelne basal telenceph, neuroepith cav cavernous sinus Cg cingulate cortex chp choroid plexus Cl claustrum CPu caudate putamen (striatum) CPune caudate putamen, neuroep CxA cortex-amyg transition Cxne neuroepithelial zone cortex CxP cortical plate EA sublenticular extend amyg f fornix fi fimbria hippocampus Fro frontal bone GP globus pallidus Hi hippocampal region HPtg hamulus pterygoid bone HyGl hyoglossus muscle ic internal capsule ictd internal carotid artery ICx intermed cortical layer Ins insular cortex IVF interventricular foramen LA lateroanterior hypothal nu LOT nu lateral olfactory tract LPtg lat pterygoid muscle LV lateral ventricle Man mandible MasM masseter muscle Mc Meckel’s cartilage MeA medial amyg nu, ant MPtg medial pterygoid muscle mxv maxillary vein NasC nasal cavity opt optic tract Oral oral cavity Pa paraventricular hypothal nu PalGl palatoglossus muscle Pir piriform cortex PLH peduncular part lat hy PSphW presphenoid wing PT paratenial thalamic nu Ptg pterygoid proces sphenoid ptgcn nerve of the pterygoid canal PVA paraventricular thal nu, ant Rt reticular thal nu SCh suprachiasmatic nu SFO subfornical organ SM nu stria medullaris sm stria medullaris thal SO supraoptic nu SOR supraoptic, retrochiasmatic sox supraoptic decussation st stria terminalis StyGl styloglossus muscle SubVCx subventricular layer cortex TempM temporalis muscle TempS temporal bone, squamous Tongue tongue TPal tensor palati muscle ZygA zygomatic arch

Figure 15 E17.5 #15 2.04 mm

1Cx CxP ICx

LV Cxne

chp

SubVCx

Hi chp

fi DR3V

CPune

Ins

CPu Cl

B ic

Re SM PaXi

Rt

Pir

PT PVA AM

st

GP

3V cst

PSphW

sm

BTelne

AA

MeA

PrTh

EA

Pa

PLH

CxA SO ACo

LOT

f

AH

opt sox

ictd

VMH

TempS 4n

3n 5Gn/5n

TempS

RCh 6n

ASph

LPtg

PSph

Cond Ptg

NasC

Mc TPal HPtg

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5Gn/5n trigem ganglion and nerve 6n root of abducens nerve AA anterior amyg area ACo ant cortical amygdaloid nu AH anterior hypothalamic area AM anteromedial thalamic nu ASph alisphenoid bone B basal nu (Meynert) BTelne basal telenceph, neuroepith chp choroid plexus Cl claustrum Cond condylar process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep cst comm stria terminalis CxA cortex-amyg transition Cxne neuroepithelial zone cortex CxP cortical plate DR3V dorsal recess third ventricle EA sublenticular extend amyg f fornix fi fimbria hippocampus GP globus pallidus Hi hippocampal region HPtg hamulus pterygoid bone ic internal capsule ictd internal carotid artery ICx intermed cortical layer Ins insular cortex LOT nu lateral olfactory tract LPtg lat pterygoid muscle LV lateral ventricle Mc Meckel’s cartilage MeA medial amyg nu, ant NasC nasal cavity opt optic tract Pa paraventricular hypothal nu PaXi paraxiphoid nu of thalamus Pir piriform cortex PLH peduncular part lat hy PrTh prethalamus PSph presphenoid bone PSphW presphenoid wing PT paratenial thalamic nu Ptg pterygoid proces sphenoid PVA paraventricular thal nu, ant RCh retrochiasmatic area Re reuniens thalamic nu Rt reticular thal nu SM nu stria medullaris sm stria medullaris thal SO supraoptic nu sox supraoptic decussation st stria terminalis SubVCx subventricular layer cortex TempS temporal bone, squamous TPal tensor palati muscle VMH ventmed hypothal nu

Figure 16 E17.5 #16 2.16 mm

1Cx CxP

LV ICx

chp

Cxne

Hi DR3V Hb PVA MD

SubVCx fi

CPune

sm LD

BTelne

CM

VL ic

Ins CPu Cl

st

Rh Re

Rt

GP La PSphW

B

Pir

BL

Pa

Me SO PLH

CxA BMA

AH

BAOT ACo

sox f PLH

opt

TempS

VMH

ictd

ASph

MTu

TMJ TempM

Arc

5Gn

Cond

5man LPtg

3V

EA I

ParP

PrTh

Ce

ASph

PSph

Otic

Mc

Aud

NasC

GeHy StyGl Hyoid

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 5Gn trigeminal ganglion 5man 5n, mandibular division ACo ant cortical amygdaloid nu AH anterior hypothalamic area Arc arcuate hypothal nu ASph alisphenoid bone Aud auditory tube B basal nu (Meynert) BAOT bed nu access olfactory tr BL basolateral amyg nu BMA basomed amyg nu, ant BTelne basal telenceph, neuroepith Ce central amygdaloid nu chp choroid plexus Cl claustrum CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep CxA cortex-amyg transition Cxne neuroepithelial zone cortex CxP cortical plate DR3V dorsal recess third ventricle EA sublenticular extend amyg f fornix fi fimbria hippocampus GeHy geniohyoid muscle GP globus pallidus Hb habenular nuclei Hi hippocampal region Hyoid hyoid bone I intercalated nuclei amyg ic internal capsule ictd internal carotid artery ICx intermed cortical layer Ins insular cortex La lat amygdaloid nu LD laterodorsal thal nu LPtg lat pterygoid muscle LV lateral ventricle Mc Meckel’s cartilage MD mediodorsal thalamic nu Me medial amygdaloid nu MTu medial tuberal nu NasC nasal cavity opt optic tract Otic otic ganglion Pa paraventricular hypothal nu ParP parietal plate Pir piriform cortex PLH peduncular part lat hy PrTh prethalamus PSph presphenoid bone PSphW presphenoid wing PVA paraventricular thal nu, ant Re reuniens thalamic nu Rh rhomboid thal nu Rt reticular thal nu sm stria medullaris thal SO supraoptic nu sox supraoptic decussation st stria terminalis StyGl styloglossus muscle SubVCx subventricular layer cortex TempM temporalis muscle TempS temporal bone, squamous TMJ temporomandibular joint VL ventrolateral thalamic nu VMH ventmed hypothal nu

Figure 17 E17.5 #17 2.28 mm

1Cx CxP

LV

ICx Cxne

DR3V

Hi

chp SubVCx

sm fi

CPune

LP

chp Hb PV MD

VL RtSt CPu

DEn

CM

VPL

st

Rh

Rt

Re

ic GP

mfb PrTh

La Ce

Pir BL ParP

I

3V Pa

Me PLH

BMA

AHP MeAV

sox MTu

opt

ACo

DM f VMH

ictd TempS

TempM

Arc

5Gn

TMJ Otic

Cond

APit ASph

Mc

BSph AudC NasC LPal GeHy Oral EpiG Hyoid Thy

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 5Gn trigeminal ganglion ACo ant cortical amygdaloid nu AHP ant hypothal area, post APit anterior lobe pituitary Arc arcuate hypothal nu ASph alisphenoid bone AudC auditory tube cartilage BL basolateral amyg nu BMA basomed amyg nu, ant BSph basisphenoid bone Ce central amygdaloid nu chp choroid plexus CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate DEn dorsal endopiriform nu DM dorsomed hypothal nu DR3V dorsal recess third ventricle EpiG epiglottis f fornix fi fimbria hippocampus GeHy geniohyoid muscle GP globus pallidus Hb habenular nuclei Hi hippocampal region Hyoid hyoid bone I intercalated nuclei amyg ic internal capsule ictd internal carotid artery ICx intermed cortical layer La lat amygdaloid nu LP lateral posterior thal nu LPal levator palati muscle LV lateral ventricle Mc Meckel’s cartilage MD mediodorsal thalamic nu Me medial amygdaloid nu MeAV med amygd nu, anterovent mfb med forebrain bundle MTu medial tuberal nu NasC nasal cavity opt optic tract Oral oral cavity Otic otic ganglion Pa paraventricular hypothal nu ParP parietal plate Pir piriform cortex PLH peduncular part lat hy PrTh prethalamus PV paraventricular thalamic nu Re reuniens thalamic nu Rh rhomboid thal nu Rt reticular thal nu RtSt reticluostrial nu sm stria medullaris thal sox supraoptic decussation st stria terminalis SubVCx subventricular layer cortex TempM temporalis muscle TempS temporal bone, squamous Thy thyroid gland TMJ temporomandibular joint VL ventrolateral thalamic nu VMH ventmed hypothal nu VPL ventral posterolat thal nu

Figure 18 E17.5 #18 2.40 mm

1Cx

LV ICx

CxP

Cxne chp

Hi

LV SubVCx

fi LP

DLG IGL

CPune

sm Hb

DG

DR3V

MD

Po VPL

CPu

st GP

DEn

Rt

st

Ce

PaXi

ZIV

PrTh EP

I Me

BLA

mfb

BMA

sox

BLV

opt

PLCo

ml Re

ZID

ic

La

Pir

CM

VPM

VG

3V

Pa

PaPo PLH

DM

ACo MTu f

ParP VMH Ptd

TempS

ictd

5Gn

Arc

TMJ Cond

MEI MEE

IPit Mc

PPit

APit BOcc TyBu

EAM

LarPh TyM

TyC

Hyoid

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 5Gn trigeminal ganglion ACo ant cortical amygdaloid nu APit anterior lobe pituitary Arc arcuate hypothal nu BLA basolat amyg nu, ant BLV basolat amyg, ventral BMA basomed amyg nu, ant BOcc basioccipital bone Ce central amygdaloid nu chp choroid plexus CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate DEn dorsal endopiriform nu DG dentate gyrus DLG dorsal lat geniculate nu DM dorsomed hypothal nu DR3V dorsal recess third ventricle EAM sublent extended amyg, med EP entopeduncular nu f fornix fi fimbria hippocampus GP globus pallidus Hb habenular nuclei Hi hippocampal region Hyoid hyoid bone I intercalated nuclei amyg ic internal capsule ictd internal carotid artery ICx intermed cortical layer IGL intergeniculate leaf IPit intermediate lobe pit La lat amygdaloid nu LarPh laryngopharynx LP lateral posterior thal nu LV lateral ventricle Mc Meckel’s cartilage MD mediodorsal thalamic nu Me medial amygdaloid nu MEE medial eminence, ext layer MEI medial eminence, internal layer mfb med forebrain bundle ml medial lemniscus MTu medial tuberal nu opt optic tract Pa paraventricular hypothal nu PaPo paraventricular hy nu, post ParP parietal plate PaXi paraxiphoid nu of thalamus Pir piriform cortex PLCo posterolat cortical amyg PLH peduncular part lat hy Po post thal nuclear group PPit posterior lobe pit PrTh prethalamus Ptd parotid gland Re reuniens thalamic nu Rt reticular thal nu sm stria medullaris thal sox supraoptic decussation st stria terminalis SubVCx subventricular layer cortex TempS temporal bone, squamous TMJ temporomandibular joint TyBu tympanic bulla TyC tympanic cavity TyM tympanic membrane VG ventral geniculate nu VMH ventmed hypothal nu VPL ventral posterolat thal nu VPM vent posteromed thal nu ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 19 E17.5 #19 2.52mm

1Cx CxP

ICx Cxne LV

Hi

chp

sm Hb

fi

SubVCx

LP Po

CPune

MD

DLG

PVP

CM

VPL VPM

CPu

DR3V

DG

VG IGL

Pir

BL

ml

ic

Ce

La

ZID ZIV

Rt

st

3V DA

EP

STIA

mfb

Me

BM

sox

PLH

opt

BLV

DM

MTu

PMCo

f

ParP

PLCo

TempS

VMH 4n

3n

ictd

6n

Arc

s5 m5

5Gn

PPit

IPit APit

Mc Rath 7n

BOcc CD TyBu

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5Gn trigeminal ganglion 6n root of abducens nerve 7n facial nerve APit anterior lobe pituitary Arc arcuate hypothal nu BL basolateral amyg nu BLV basolat amyg, ventral BM basomedial amyg nu BOcc basioccipital bone CD cochlear duct Ce central amygdaloid nu chp choroid plexus CM central medial thal nu CPu caudate putamen (striatum) CPune caudate putamen, neuroep Cxne neuroepithelial zone cortex CxP cortical plate DA dorsal hypothal area DG dentate gyrus DLG dorsal lat geniculate nu DM dorsomed hypothal nu DR3V dorsal recess third ventricle EP entopeduncular nu f fornix fi fimbria hippocampus Hb habenular nuclei Hi hippocampal region ic internal capsule ictd internal carotid artery ICx intermed cortical layer IGL intergeniculate leaf IPit intermediate lobe pit La lat amygdaloid nu LP lateral posterior thal nu LV lateral ventricle m5 motor root trigeminal nerve Mc Meckel’s cartilage MD mediodorsal thalamic nu Me medial amygdaloid nu mfb med forebrain bundle ml medial lemniscus MTu medial tuberal nu opt optic tract ParP parietal plate Pir piriform cortex PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PPit posterior lobe pit PVP paraventricular thal nu, post Rath Rathke’s pouch Rt reticular thal nu s5 sensory root trigem n sm stria medullaris thal sox supraoptic decussation st stria terminalis STIA ST, intraamygdaloid div SubVCx subventricular layer cortex TempS temporal bone, squamous TyBu tympanic bulla VG ventral geniculate nu VMH ventmed hypothal nu VPL ventral posterolat thal nu VPM vent posteromed thal nu ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 20 E17.5 #20 2.64 mm

LV 1Cx CxP

chp

Cxne

ICx

DG

Hi

DR3V

sm Hb

SubVCx

fi LP

CPu

fr DLG MD PVP Po

VPM VG

VPL opt IGL

rf BTelne

RRe

ZID ZIV

La Pir

CM ml

Ce Me STIA

BL

PrTh

SubG ic

3V

mfb

BM

DM PLH

PLCo

PMCo

4n

ParP

PeF

Arc

MTu

5n

5Gn

VMH

pcer

3n

6n TempS

f

APit Mall CGn 7n

CD

CGn 8cn

HMall

BOcc

CD

Corti

TyC

EAM

LgCa

TyBu SalPh

StyPh

ictd

LarPh

StyGl StyHy Clav

Ary

PDig

StM

Hyoid

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

Lar

0.8

1.0 mm

1Cx layer 1 of developing cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5Gn trigeminal ganglion 5n trigeminal nerve 6n root of abducens nerve 7n facial nerve 8cn cochlear root 8th nerve APit anterior lobe pituitary Arc arcuate hypothal nu Ary arytenoid cartilage BL basolateral amyg nu BM basomedial amyg nu BOcc basioccipital bone BTelne basal telenceph, neuroepith CD cochlear duct Ce central amygdaloid nu CGn cochlear (spiral) ganglion chp choroid plexus Clav clavicle CM central medial thal nu Corti organ of Corti CPu caudate putamen (striatum) Cxne neuroepithelial zone cortex CxP cortical plate DG dentate gyrus DLG dorsal lat geniculate nu DM dorsomed hypothal nu DR3V dorsal recess third ventricle EAM sublent extended amyg, med f fornix fi fimbria hippocampus fr fasciculus retroflexus Hb habenular nuclei Hi hippocampal region HMall handle of malleus Hyoid hyoid bone ic internal capsule ictd internal carotid artery ICx intermed cortical layer IGL intergeniculate leaf La lat amygdaloid nu Lar larynx LarPh laryngopharynx LgCa longus capitis muscle LP lateral posterior thal nu LV lateral ventricle Mall malleus MD mediodorsal thalamic nu Me medial amygdaloid nu mfb med forebrain bundle ml medial lemniscus MTu medial tuberal nu opt optic tract ParP parietal plate pcer post cerebral art PDig post belly digastric PeF perifornical nu Pir piriform cortex PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PrTh prethalamus PVP paraventricular thal nu, post rf rhinal fissure RRe retrouniens area SalPh salpingopharyngeus muscle sm stria medullaris thal STIA ST, intraamygdaloid div StM sternomastoid muscle StyGl styloglossus muscle StyHy stylohyoid muscle StyPh stylopharyngeus muscle SubG subgeniculate nu SubVCx subventricular layer cortex TempS temporal bone, squamous TyBu tympanic bulla TyC tympanic cavity VG ventral geniculate nu VMH ventmed hypothal nu VPL ventral posterolat thal nu VPM vent posteromed thal nu ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 21 E17.5 #21 2.76 mm

Cx1 CxP

LV

ICx SubVCx Cxne chp

S Hi Hb

fi

LP

fr

DLG

MD

Po

PV

IGL VG

Pir

VPM VPL

BTelne

ml opt

SubG ZIV ic

Amg

RRe sl

ZID scp

PrTh

3V

STh

LV

mfb

DM

PLH f

MTu

VMH PeF

ParP

Arc

5n 5Gn

TempS

VLL

Mall

VMPO bas

7n

8cn

CD

CGn

HMall EAM

CD

TyC

BOcc

TyBu

StyHy

ijugv

SalPh

StyPh

StyGl

LgCa LarPh

ictd

PDig

Ary

StM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Thy

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5Gn trigeminal ganglion 5n trigeminal nerve 7n facial nerve 8cn cochlear root 8th nerve Amg amygdala Arc arcuate hypothal nu Ary arytenoid cartilage bas basilar artery BOcc basioccipital bone BTelne basal telenceph, neuroepith CD cochlear duct CGn cochlear (spiral) ganglion chp choroid plexus Cx1 developing Cx, layer 1 Cxne neuroepithelial zone cortex CxP cortical plate DLG dorsal lat geniculate nu DM dorsomed hypothal nu EAM sublent extended amyg, med f fornix fi fimbria hippocampus fr fasciculus retroflexus Hb habenular nuclei Hi hippocampal region HMall handle of malleus ic internal capsule ictd internal carotid artery ICx intermed cortical layer IGL intergeniculate leaf ijugv internal jugular vein LarPh laryngopharynx LgCa longus capitis muscle LP lateral posterior thal nu LV lateral ventricle Mall malleus MD mediodorsal thalamic nu mfb med forebrain bundle ml medial lemniscus MTu medial tuberal nu opt optic tract ParP parietal plate PDig post belly digastric PeF perifornical nu Pir piriform cortex PLH peduncular part lat hy Po post thal nuclear group PrTh prethalamus PV paraventricular thalamic nu RRe retrouniens area S subiculum SalPh salpingopharyngeus muscle scp superior Cb peduncle sl sulcus limitans STh subthalamic nu StM sternomastoid muscle StyGl styloglossus muscle StyHy stylohyoid muscle StyPh stylopharyngeus muscle SubG subgeniculate nu SubVCx subventricular layer cortex TempS temporal bone, squamous Thy thyroid gland TyBu tympanic bulla TyC tympanic cavity VG ventral geniculate nu VLL ventral nu lat lemniscus VMH ventmed hypothal nu VMPO ventmed preoptic nu VPL ventral posterolat thal nu VPM vent posteromed thal nu ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 22 E17.5 #22 2.88mm

RSD LV

RSG

chp

1Cx CxP

S

LHb MHb

Cxne ICx fi

SubVCx

LP

Hi bsc

fr PF

DLG Po

MD

VPM VG Hi

IGL

VPL

ZID ZIV ic

BTelne

rf

STh

CM ml VPPC RRe 3V PR SPF PH

mfb PLH

LV

PSTh

Entne

f MB Arc Arc

VTM ParP

3V ME

tzx VLL CAT

5n 5Gn

RPa Tz

Inc

MVPO

TempP CGn 7n

8cn bas

HMall

CGn CD

TyC

LReCa

EAM

LgCa

TyBu

Rc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

BOcc

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 5Gn trigeminal ganglion 5n trigeminal nerve 7n facial nerve 8cn cochlear root 8th nerve Arc arcuate hypothal nu bas basilar artery BOcc basioccipital bone bsc brachium superior colliculus BTelne basal telenceph, neuroepith CAT nu central acoustic tr CD cochlear duct CGn cochlear (spiral) ganglion chp choroid plexus CM central medial thal nu Cxne neuroepithelial zone cortex CxP cortical plate DLG dorsal lat geniculate nu EAM sublent extended amyg, med Entne entorh cx neuroepithelial f fornix fi fimbria hippocampus fr fasciculus retroflexus Hi hippocampal region HMall handle of malleus ic internal capsule ICx intermed cortical layer IGL intergeniculate leaf Inc incus LgCa longus capitis muscle LHb lateral habenular nu LP lateral posterior thal nu LReCa lat rectus capitis muscle LV lateral ventricle MB mammillary body MD mediodorsal thalamic nu ME median eminence mfb med forebrain bundle MHb med habenular nu ml medial lemniscus MVPO medioventral periolivary nu ParP parietal plate PF parafascicular thal nu PH posterior hypothal nu PLH peduncular part lat hy Po post thal nuclear group PR prerubral field PSTh parasubthalamic nu Rc Reichert’s cartilage rf rhinal fissure RPa raphe pallidus nu RRe retrouniens area RSD retrosplenial dysgranular cx RSG retrosplenial granular cx S subiculum SPF subparafascicular thal nu STh subthalamic nu SubVCx subventricular layer cortex TempP temporal bone, petrous TyBu tympanic bulla TyC tympanic cavity Tz nu trapezoid body tzx decuss trapezoid body VG ventral geniculate nu VLL ventral nu lat lemniscus VPL ventral posterolat thal nu VPM vent posteromed thal nu VPPC vent post nu th, parvicellular VTM vent tuberomammillary nu ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 23 E17.5 #23 3.00 mm

RSD LV

1Cx CxP

RSG OPT

SubV

ICx

Cxne

PrC

OT

PF

LP DLG

PC CM VPM VPL RRe VPPC sl ml

IGL VG

Hi

3V

fr

Po

ZID

PR PH

ZIV mfb

STh

mt SuM

PLH

MM ML LM 3V

Entne Ent

VLL

ParP 5n TempP

IntA

Sp5O SOl

Sacc

LPGi

Mall BStap

RIP

Tz

tz 7n

Inc

Pr5

P7

OvalW

7N

ml

8cn

EAM CD

RPa

CGn

TyC BOcc

7n Rc

LReCa

TyBu

ijugv

StHy StM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

LgCa

ictd

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 5n trigeminal nerve 7N facial nu 7n facial nerve 8cn cochlear root 8th nerve BOcc basioccipital bone BStap base of stapes CD cochlear duct CGn cochlear (spiral) ganglion CM central medial thal nu Cxne neuroepithelial zone cortex CxP cortical plate DLG dorsal lat geniculate nu EAM sublent extended amyg, med Ent entorhinal cortex Entne entorh cx neuroepithelial fr fasciculus retroflexus Hi hippocampal region ictd internal carotid artery ICx intermed cortical layer IGL intergeniculate leaf ijugv internal jugular vein Inc incus IntA interposed cerebellar nu, ant LgCa longus capitis muscle LM lateral mammillary nu LP lateral posterior thal nu LPGi lat paragigantocellular nu LReCa lat rectus capitis muscle LV lateral ventricle Mall malleus mfb med forebrain bundle ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial mt mammillothalamic tract OPT olivary pretectal nu OT nu of the optic tract OvalW oval window P7 perifacial zone ParP parietal plate PC paracentral thal nu PF parafascicular thal nu PH posterior hypothal nu PLH peduncular part lat hy Po post thal nuclear group PR prerubral field Pr5 principal sensory trigem nu PrC precommissural nu Rc Reichert’s cartilage RIP raphe interpositus nu RPa raphe pallidus nu RRe retrouniens area RSD retrosplenial dysgranular cx RSG retrosplenial granular cx Sacc saccule sl sulcus limitans SOl superior olive, lateral Sp5O spinal trigeml nu, oral STh subthalamic nu StHy striohypothalamic nu StM sternomastoid muscle SubV submedius thal nu, ventral SuM supramammillary nu TempP temporal bone, petrous TyBu tympanic bulla TyC tympanic cavity Tz nu trapezoid body tz trapezoid body VG ventral geniculate nu VLL ventral nu lat lemniscus VPL ventral posterolat thal nu VPM vent posteromed thal nu VPPC vent post nu th, parvicellular ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 24 E17.5 #24 3.12mm

RSD Pi

LV 1Cx CxP ICx SubV

RSG

MPT

OPT APT

PrC

LP

Cxne

PF fr

DLG Po

S DG

pc

VPL VPM VG IGL ml ZID opt

VPPC PR mtg PH

mfb

STh

Ent

RRe

ZIV

cp

3V

CM

SuM PLH SuML mp pm MM LM ML Arc tfp VLL

Entne pcer

lfp

Pn

Pn

PnO 5TT

Pr5 Sp5O

7n 7n

BStap

StapM TyC

RIP Gi GiA

LPGi

HStap

EAM

7n rs A5

IntA

Sacc

PnC

7N RMg

CD 8cn CGn

7n

RPa ml bas

TyBu Rc

LReCa LgCa

StM

OmHy Scap

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 5TT motor trigem, tensor tymp 7N facial nu 7n facial nerve 8cn cochlear root 8th nerve A5 A5 noradrenaline cells APT anterior pretectal nu Arc arcuate hypothal nu bas basilar artery BStap base of stapes CD cochlear duct CGn cochlear (spiral) ganglion CM central medial thal nu cp cerebral peduncle Cxne neuroepithelial zone cortex CxP cortical plate DG dentate gyrus DLG dorsal lat geniculate nu EAM sublent extended amyg, med Ent entorhinal cortex Entne entorh cx neuroepithelial fr fasciculus retroflexus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha HStap handle of stapes ICx intermed cortical layer IGL intergeniculate leaf IntA interposed cerebellar nu, ant lfp longitudinal fasciculus pons LgCa longus capitis muscle LM lateral mammillary nu LP lateral posterior thal nu LPGi lat paragigantocellular nu LReCa lat rectus capitis muscle LV lateral ventricle mfb med forebrain bundle ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial mp mammillary peduncle MPT medial pretectal nu mtg mammillotegmental tract OmHy omohyoid muscle OPT olivary pretectal nu opt optic tract pc posterior comm pcer post cerebral art PF parafascicular thal nu PH posterior hypothal nu Pi pineal gland PLH peduncular part lat hy pm principal mammillary tr Pn pontine nuclei PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Po post thal nuclear group PR prerubral field Pr5 principal sensory trigem nu PrC precommissural nu Rc Reichert’s cartilage RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu RRe retrouniens area rs rubrospinal tract RSD retrosplenial dysgranular cx RSG retrosplenial granular cx S subiculum Sacc saccule Scap scapula Sp5O spinal trigeml nu, oral StapM stapedius muscle STh subthalamic nu StM sternomastoid muscle SubV submedius thal nu, ventral SuM supramammillary nu SuML supramammillary nu, lat tfp transverse fibers pons TyBu tympanic bulla TyC tympanic cavity VG ventral geniculate nu VLL ventral nu lat lemniscus VPL ventral posterolat thal nu VPM vent posteromed thal nu VPPC vent post nu th, parvicellular ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 25 E17.5 #25 3.24 mm

RSD ICx CxP ICx SubV

MPT

RSG

LP

Cxne

PPT OPT

OT APT

3V PF

PrS

Po

MG

REth

VPM LV

VG

fr

Eth

PR PrTh

F

ZID

A11

RI

PaS mtg

ZIV Entne

PSTh mfb PLH

cp pcer

Gem

sumx

SuM mp ML

MM MRe Arc Pn lfp Pn lfp

Ent VLL mcp

RtTg

PnO

Pr5

PHA

5TT TempP

StapM

PnC

m5 7n

8vn OvalW Sacc

rs

7n BStap

Gi

Sp5O VeGn

P7

7L

CD EAM

7n

LPGi GiA RMg ml RPa py bas

CD TyBu 7DI 7DM

BOcc

10Gn

LReCa Atlas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5TT motor trigem, tensor tymp 7DI facial nu, dors intermedial 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7n facial nerve 8vn vestibular root of 8th nerve 10Gn vagus nerve ganglion A11 A11 dopamine cells APT anterior pretectal nu Arc arcuate hypothal nu Atlas atlas bas basilar artery BOcc basioccipital bone BStap base of stapes CD cochlear duct cp cerebral peduncle Cxne neuroepithelial zone cortex CxP cortical plate EAM sublent extended amyg, med Ent entorhinal cortex Entne entorh cx neuroepithelial Eth ethmoid thalamic nu F nu fields of Forel fr fasciculus retroflexus Gem gemini hypothalamic nu Gi gigantocellular reticular nu GiA gigantocellular retic, alpha ICx intermed cortical layer lfp longitudinal fasciculus pons LP lateral posterior thal nu LPGi lat paragigantocellular nu LReCa lat rectus capitis muscle LV lateral ventricle m5 motor root trigeminal nerve mcp middle cerebellar peduncle mfb med forebrain bundle MG med geniculate nu ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial mp mammillary peduncle MPT medial pretectal nu MRe mammillary recess 3V mtg mammillotegmental tract OPT olivary pretectal nu OT nu of the optic tract OvalW oval window P7 perifacial zone PaS parasubiculum pcer post cerebral art PF parafascicular thal nu PHA posterior hypothal area PLH peduncular part lat hy Pn pontine nuclei PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Po post thal nuclear group PPT posterior pretectal nu PR prerubral field Pr5 principal sensory trigem nu PrS presubiculum PrTh prethalamus PSTh parasubthalamic nu py pyramidal tr REth retroethmoid nu RI rostral interstitial nu of mlf RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract RSD retrosplenial dysgranular cx RSG retrosplenial granular cx RtTg reticulotegmental nu pons Sacc saccule Sp5O spinal trigeml nu, oral StapM stapedius muscle SubV submedius thal nu, ventral SuM supramammillary nu sumx supramammillary decuss TempP temporal bone, petrous TyBu tympanic bulla VeGn vestibular n ganglion VG ventral geniculate nu VLL ventral nu lat lemniscus VPM vent posteromed thal nu ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 26 E17.5 #26 3.36 mm

1Cx

CxP

Pi

RSD

ICx SubVCx Cxne

RSG bsc PPT OPT RPF LP OT APT Po

LV

MG

p1PAG Dk

PoT PIL

Ent

fr

mtg

RPC

PHA sumx ML MM

SN PLH SuML

cp

Ent

pcer

ParP

5TT

Arc tfp

VLL PMnR PnO

A7 Pr5 VCA

3V

RI PrTh

ml

Entne

Com pc MCPC Aq Lth

5N

MnR PnC SubCD

PCRtA

4V

ASCC 7n

TempP

HSCCA

ne

Sp5O PCRt Utr

EAM

VeGn

IRt GiA

P7

Sacc

7n

Gi

7N RPa

LPGi

StapM

RMg bas StM

BOcc LReCa Atlas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 3V 3rd ventricle 4V 4th ventricle 5N motor trigeminal nu 5TT motor trigem, tensor tymp 7N facial nu 7n facial nerve A7 A7 noradrenaline cells APT anterior pretectal nu Aq aqueduct Arc arcuate hypothal nu ASCC anterior semicirc canal Atlas atlas bas basilar artery BOcc basioccipital bone bsc brachium superior colliculus Com commissural nu inf colliculus cp cerebral peduncle Cxne neuroepithelial zone cortex CxP cortical plate Dk nu of Darkschewitsch EAM sublent extended amyg, med Ent entorhinal cortex Entne entorh cx neuroepithelial fr fasciculus retroflexus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha HSCCA horizontal SCC ICx intermed cortical layer IRt intermed reticular nu LP lateral posterior thal nu LPGi lat paragigantocellular nu LReCa lat rectus capitis muscle Lth lithoid nu LV lateral ventricle MCPC magnocell nu post comm MG med geniculate nu ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MnR median raphe nu mtg mammillotegmental tract ne neuroepithelium OPT olivary pretectal nu OT nu of the optic tract P7 perifacial zone p1PAG p1 periaqueductal gray ParP parietal plate pc posterior comm pcer post cerebral art PCRt parvicell reticular nu PCRtA parvicell reticular nu, alpha PHA posterior hypothal area Pi pineal gland PIL post intralaminar thal nu PLH peduncular part lat hy PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Po posterior thalamic nu PoT posterior thal nu, triangular PPT posterior pretectal nu Pr5 principal sensory trigem nu PrTh prethalamus RI rostral interstitial nu of mlf RMg raphe magnus nu RPa raphe pallidus nu RPC red nu, parvicell part RPF retroparafascicular nu RSD retrosplenial dysgranular cx RSG retrosplenial granular cx Sacc saccule SN substantia nigra Sp5O spinal trigeml nu, oral StapM stapedius muscle StM sternomastoid muscle SubCD subcoeruleus nu, dorsal SubVCx subventricular layer cortex SuML supramammillary nu, lat sumx supramammillary decuss TempP temporal bone, petrous tfp transverse fibers pons Utr utricle VCA ventral cochlear nu, ant VeGn vestibular n ganglion VLL ventral nu lat lemniscus

Figure 27 E17.5 #27 3.48 mm

Pi 1Cx CxP

ICx

SC csc OT PCom TG

SubVCx Cxne

Aq

p1PAG APT LP OPT Dk Po Inc MG PrEW RPC mtg SubB ml fr PBP RLi SN VTAR cp IP

Entne Ent ParP

IPF PMnR

VLL ll

MnR

5TT

Pn

A7 PrS

PnO

5N m5

SubC DMTg

mlf

EVe g7

4V

Sp5O PCRtA

VCA

sp5

6N

PCRt

VCP

IRt

Sp5I

mlf Gi

7SH GiA

7N LPGi

RPa RMg

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 4V 4th ventricle 5N motor trigeminal nu 5TT motor trigem, tensor tymp 6N abducens nu 7N facial nu 7SH facial motor nu, stylohyoid A7 A7 noradrenaline cells APT anterior pretectal nu Aq aqueduct cp cerebral peduncle csc comm superior colliculus Cxne neuroepithelial zone cortex CxP cortical plate Dk nu of Darkschewitsch DMTg dorsomed tegmental area Ent entorhinal cortex Entne entorh cx neuroepithelial EVe nu origin efferents ve n fr fasciculus retroflexus g7 genu facial nerve Gi gigantocell retic nu GiA gigantocellular retic, alpha ICx intermed cortical layer Inc incus IP interpedunc nu IPF interpedunc fossa IRt intermed reticular nu ll lateral lemniscus LP lateral posterior thal nu LPGi lat paragigantocellular nu m5 motor root trigeminal nerve MG med geniculate nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu mtg mammillotegmental tract OPT olivary pretectal nu OT nu of the optic tract p1PAG p1 periaqueductal gray ParP parietal plate PBP parabrachial pigmented nu PCom nu posterior comm PCRt parvicell reticular nu PCRtA parvicell reticular nu, alpha Pi pineal gland PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Po post thal nuclear group PrEW pre-Edinger-Westphal nu PrS presubiculum RLi rostral linear nu raphe RMg raphe magnus nu RPa raphe pallidus nu RPC red nu, parvicell part SC superior colliculus SN substantia nigra sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sp5O spinal trigeml nu, oral SubB subbrachial nu SubC subcoeruleus nu SubVCx subventricular layer cortex TG tectal gray VCA ventral cochlear nu, ant VCP vent cochlear nu, posterior VLL ventral nu lat lemniscus VTAR vent tegmental area, rostr

Figure 28 E17.5 #28 3.60 mm

CxP ne

SC

1Cx ne bsc

ICx

p1PAG

LP APT

SubV

Aq

OT TG

MG

p1Rt Dk

Po

InC

SubB

RPC PBP

MA3 RLi IF

scp fr mtg

cp SN

PIF ParP

tfp

VLL

MPL PMnR SubCV PnO MnR A7 5N SubCD PCRtA DMTg CGA

5TT Pr5 ASCC

VeGn VCA tz

HSCCA Pinna

EVe

HSCC TempP

mlf CGO 4V

g7

Sp5O sp5

Utr

mlf

Sp5I

ELS

SGe

MVe 6N PCRt IRt

Gi 7SH GiA

7N LPGi

emv

9/10/11n

RMg ml RPa

TzM Mst

ijugv

py

emv

LgsCa

BOcc

12n ijugv

I9Gn

bas

Atlas

Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 4V 4th ventricle 5N trigeminal motor nu 5TT motor trigem, tensor tymp 6N abducens nu 7N facial nu 7SH facial motor nu, stylohyoid 9/10/11n 9n, 10n, and 11n 12n root of hypoglossal nerve A7 A7 noradrenaline cells APT anterior pretectal nu ASCC anterior semicirc canal Atlas atlas Axis axis (C2 vertebra) bas basilar artery BOcc basioccipital bone bsc brachium superior colliculus CGA central gray, alpha part CGO central gray, nu O cp cerebral peduncle CxP cortical plate Dk nu of Darkschewitsch DMTg dorsomed tegmental area ELS endolymphatic sac emv emissary vein EVe nu origin efferents ve n fr fasciculus retroflexus g7 genu facial nerve Gi gigantocellular reticular nu GiA gigantocellular retic, alpha HSCC horizontal semicircular canal HSCCA horizontal SCC I9Gn inferior ganglion 9n ICx intermed cortical layer IF interfascicular nu ijugv internal jugular vein InC interstitial nu of Cajal IRt intermed reticular nu LgsCa longissimus capitis muscle LP lateral posterior thal nu LPGi lat paragigantocellular nu MA3 med access oculomotor nu MG med geniculate nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu Mst mastoid process mtg mammillotegmental tract MVe medial vestibular nu ne neuroepithelium OT nu of the optic tract p1PAG p1 periaqueductal gray ParP parietal plate PBP parabrachial pigmented nu PCRt parvicell reticular nu PCRtA parvicell reticular nu, alpha PIF parainterfascicular nu VTA Pinna pinna of the ear PMnR paramedian raphe nu PnO pontine reticular nu, oral Po post thal nuclear group Pr5 principal sensory trigem nu py pyramidal tr RLi rostral linear nu raphe RMg raphe magnus nu RPa raphe pallidus nu RPC red nu, parvicell part Rt reticular thal nu SC superior colliculus scp superior Cb peduncle SGe supragenual nu SN substantia nigra sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sp5O spinal trigeml nu, oral SubB subbrachial nu SubCD subcoeruleus nu, dorsal SubCV subcoeruleus nu, ventral SubV submedius thal nu, ventral TempP temporal bone, petrous tfp transverse fibers pons TG tectal gray tz trapezoid body TzM trapezius muscle Utr utricle VCA ventral cochlear nu, ant VeGn vestibular n ganglion VLL ventral nu lat lemniscus

Figure 29 E17.5 #29 3.72 mm

1Cx CxP

csc SC mPAG

Cxne

Aq

p1Rt

LP APT

Dk

MG

InC SubG

MA3

RPC

VTAR PBP mtg PIF RLi fr IF

SN cp

mcp ILL MPL sp5

SubC DMTg mlf ne SuVe CG 4V icp CGB MVe VCA SpVe 8n SGe

ASCC

5N

HSCC

Sp5O 5Sol sp5

ELS TempP

PCRt Gi

7N 9/10/11n TzM

6N IRt

Sp5I

HSCC PSCCA PSCC

LgsCa

PMnR

MnR PnO

A7 Pr5

tfp

LPGi

GiV IO

ijugv Occ

emv

py

12n

RPa

BOcc

Atlas Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cx layer 1 of developing cortex 4V 4th ventricle 5N motor trigeminal nu 5Sol trigeminal-solitary trans 6N abducens nu 7N facial nu 8n vestibulocochlear nerve 9/10/11n 9n, 10n, and 11n 12n root of hypoglossal nerve A7 A7 noradrenaline cells APT anterior pretectal nu Aq aqueduct ASCC anterior semicirc canal Atlas atlas Axis axis (C2 vertebra) BOcc basioccipital bone CG central gray CGB central gray, beta part cp cerebral peduncle csc comm superior colliculus Cxne neuroepithelial zone cortex CxP cortical plate Dk nu of Darkschewitsch DMTg dorsomed tegmental area ELS endolymphatic sac emv emissary vein fr fasciculus retroflexus Gi gigantocellular reticular nu GiV gigantocellular retic, vent HSCC horizontal semicircular canal icp inf cerebellar peduncle IF interfascicular nu ijugv internal jugular vein ILL intermed nu lat lemniscus InC interstitial nu of Cajal IO inferior olivary nu IRt intermed reticular nu LgsCa longissimus capitis muscle LP lateral posterior thal nu LPGi lat paragigantocellular nu MA3 med access oculomotor nu mcp middle cerebellar peduncle MG med geniculate nu mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu mRt mesenceph retic form mtg mammillotegmental tract MVe medial vestibular nu ne neuroepithelium Occ occipital bone p1PAG p1 periaqueductal gray PBP parabrachial pigmented nu PCRt parvicell reticular nu PIF parainterfascicular nu VTA PMnR paramedian raphe nu PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PSCC post semicircular canal PSCCA post ampulla py pyramidal tr RLi rostral linear nu raphe RPa raphe pallidus nu RPC red nu, parvicell part SC superior colliculus SGe supragenual nu SN substantia nigra sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sp5O spinal trigeml nu, oral SpVe spinal vestibular nu SubC subcoeruleus nu SubG subgeniculate nu SuVe superior vestibular nu TempP temporal bone, petrous tfp transverse fibers pons TzM trapezius muscle VCA ventral cochlear nu, ant VTAR vent tegmental area, rostr

Figure 30 E17.5 #30 3.84 mm

SC LP p1Rt

MG SubB

InC

PaR

R SN

ml cp

mtg

ILL

fr IPF

MPL PMnR PnO

ParP Su5 vsc

ASCC

MnR

KF

LR4V Cb

mlf SuVe

icp

CG

LVe

4V

MVe VC occs

TempP ELS CCrus

Pinna HSCC

TzM LgsCa

MA3 RLi IF

PBP VTA

mcp

trs

Aq

mPAG

SpVe sol IS Sol 5Sol sp5 PCRt Sp5I IRt Amb

HSCC

SGe 6N

mlf

asc7 DPGi

Gi 9n ROb 10n vsc PSCC 11n GiV LPGi JugF dsc/oc IO RPa ijugv SObCa py FMag Occ Alar DAx AtOc Atlas AtAx

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

Axis

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solit trans 6N abducens nu 9n glossopharyngeal nerve 10n vagus nerve 11n root of accessory nerve Alar alar ligament dens Amb ambiguus nu Aq aqueduct asc7 ascending fibers facial n ASCC anterior semicirc canal AtAx atlantoaxial joint Atlas atlas AtOc atlantooccipital joint Axis axis (C2 vertebra) Cb cerebellum CCrus common crus CG central gray cp cerebral peduncle DAx dens of the axis DPGi dors paragigantocellular nu dsc/oc dors spino / olivocereb tr ELS endolymphatic sac FMag foramen magnum fr fasciculus retroflexus Gi gigantocellular reticular nu GiV gigantocellular retic, vent HSCC horizontal semicircular canal icp inf cerebellar peduncle IF interfascicular nu ijugv internal jugular vein ILL intermed nu lat lemniscus InC interstitial nu of Cajal IO inferior olivary nu IPF interpedunc fossa IRt intermed reticular nu IS inferior salivatory nu JugF jugular foramen KF Kˆlliker-Fuse nu LgsCa longissimus capitis muscle LP lateral posterior thal nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu MA3 med access oculomotor nu mcp middle cerebellar peduncle MG med geniculate nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu mRt mesenceph retic form mtg mammillotegmental tract MVe medial vestibular nu Occ occipital bone occs occipital sinus p1PAG p1 periaqueductal gray PaR pararubral nu ParP parietal plate PBP parabrachial pigmented nu PCRt parvicell reticular nu Pinna pinna of the ear PMnR paramedian raphe nu PnO pontine reticular nu, oral PSCC post semicircular canal py pyramidal tr R red nu RLi rostral linear nu raphe ROb raphe obscurus nu RPa raphe pallidus nu SC superior colliculus SGe supragenual nu SN substantia nigra SObCa superior oblique Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu Su5 supratrigeminal nu SubB subbrachial nu SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus TzM trapezius muscle VC ventral cochlear nu vsc ventral spinocerebellar tr VTA vent tegmental area

Figure 31 E17.5 #31 3.96 mm

Aq

SC bic

BIC

mPAG mRt

SubB

3N mtg

RMC SN

PBP ml

cp MPL ILL

ParB vsc

RLi

VTA

IPF

fr IPL

IPC PMnR

PnO

Su5 KF

mcp

scp MPB

Cb

SuVe

EGL

VeCb

CG

LR4V ASCC VC icp TempP

LVe

MVe SpVe sol

Sp5I

CCrus

sp5

mlf

PCRt DPGi

IRt

HSCC

ROb

Gi

PSCC

vsc

JugF

IOD LPGi

dsc/oc

SObCa

IOPr

Occ TzM

FMag Alar

AtOc LgsCa

CeAu

Pr

Sol 5Sol

ELS

Pinna

4V sl

Atlas

Atlas

IOM RPa py

bas DAx

AtAx

IObCa Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3N oculomotor nu 4V 4th ventricle 5Sol trigeminal-solitary trans Alar alar ligament dens Aq aqueduct ASCC anterior semicirc canal AtAx atlantoaxial joint Atlas atlas AtOc atlantooccipital joint Axis axis (C2 vertebra) bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus Cb cerebellum CCrus common crus CeAu cervicoauricular muscle CG central gray cp cerebral peduncle DAx dens of the axis DPGi dors paragigantocellular nu dsc/oc dors spino / olivocereb tr EGL external granular layer Cb ELS endolymphatic sac FMag foramen magnum fr fasciculus retroflexus Gi gigantocellular reticular nu HSCC horizontal semicircular canal icp inf cerebellar peduncle ILL intermed nu lat lemniscus IObCa inf oblique capitis IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IPC IPC nu, caudal IPF interpedunc fossa IPL interpedunc nu, lat subnu IRt intermed reticular nu JugF jugular foramen KF Kˆlliker-Fuse nu LgsCa longissimus capitis muscle LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu mcp middle cerebellar peduncle ml medial lemniscus mlf med longitudinal fasciculus MPB medial parabrachial nu MPL medial paralemniscial nu mRt mesenceph retic form mtg mammillotegmental tract MVe medial vestibular nu Occ occipital bone PAG periaqueductal gray ParB parietal bone PBP parabrachial pigmented nu PCRt parvicell reticular nu Pinna pinna of the ear PMnR paramedian raphe nu PnO pontine reticular nu, oral Pr prepositus nu PSCC post semicircular canal py pyramidal tr RLi rostral linear nu raphe RPa raphe pallidus nu RMC red nu, magnocell part ROb raphe obscurus nu SC superior colliculus scp superior Cb peduncle sl sulcus limitans SN substantia nigra SObCa superior oblique Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu Su5 supratrigeminal nu SubB subbrachial nu SuVe superior vestibular nu TempP temporal bone, petrous TzM trapezius muscle VC ventral cochlear nu VeCb vestibulocerebellar nu vsc ventral spinocerebellar tr VTA vent tegmental area

Figure 32 E17.5 #32 4.08 mm

SC

mPAG

bic

Aq

Su3C mRt Su3 3PC

BIC SubB

3N mlf

PaR R SN cp

RLi

VTA RRF PTg

IP IP

RR DLL

ts PMnR

PnO

vsc

trs

EGL

MPB LC KF mcp scp LPB

LDTg

CG

SuVe ASCC

SpVe MVe sol X Sol Pr 5Sol PCRt

CCrus ELS

sp5

TempP

4V

DC icp

LR4V

Sp5I

PSCC occs

DPGi IRt

Amb

vsc

mlf

ROb

Gi

LPGi IOD Occ

IOM dsc/oc

RPa IOPr

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

bas

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular 4V 4th ventricle 5Sol trigeminal-solit trans Amb ambiguus nu Aq aqueduct ASCC anterior semicirc canal bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CCrus common crus CG central gray cp cerebral peduncle DC dorsal cochlear nu DLL dorsal nu lateral lemniscus DPGi dors paragigantocellular nu dsc/oc dors spino / olivocereb tr EGL external granular layer Cb ELS endolymphatic sac Gi gigantocellular reticular nu icp inf cerebellar peduncle IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IP interpedunc nu IRt intermed reticular nu KF Kˆlliker-Fuse nu LC locus coeruleus LDTg laterodor tegmental nu LPB lateral parabrachial nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle mcp middle cerebellar peduncle mlf med longitudinal fasciculus MPB medial parabrachial nu mRt mesenceph retic form MVe medial vestibular nu Occ occipital bone occs occipital sinus PAG periaqueductal gray PaR pararubral nu PCRt parvicell reticular nu PMnR paramedian raphe nu PnO pontine reticular nu, oral Pr prepositus nu PSCC post semicircular canal PTg pedunculopontine tegmental R red nu RLi rostral linear nu raphe ROb raphe obscurus nu RPa raphe pallidus nu RR retrorubral nu RRF retrorubral field SC superior colliculus scp superior Cb peduncle SN substantia nigra Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu Su3 supraoculomotor PAG Su3C supraoculomotor cap SubB subbrachial nu SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus ts tectospinal tr vsc ventral spinocerebellar tr VTA vent tegmental area X nu X

Figure 33 E17.5 #33 4.20 mm

SC Aq

mPAG bic

IC

MA3 Su3 3PC 3N PaR

BIC

RMC

cp SN

scp

RRF RR ParB

PTg

SPTg ATg

DLL

VTg

LPBE scp

EGL mcp

trs

SuVe

Cb

CLi mlf xscp

LDTg

SubC LC

Bar

ASCC LR4V chp

DC

icp

SpVe

ELS CCrus

MVe

Sol 5Sol Sp5I

TempP

4V

Pr PCRt

occs sp5 pica

IRt Amb

mlf DPGi ROb

PSCC Occ

Gi IOD

LRt

SObCa

IOM

IOPr vert

RPa vert

Atlas CeAu

asp TzM Fat

Axis

vc

VH LgsCa lc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

CC

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular 4V 4th ventricle 5Sol trigeminal-solit trans Amb ambiguus nu Aq aqueduct ASCC anterior semicirc canal asp anterior spinal artery ATg anterior tegmental nu Atlas atlas Axis axis (C2 vertebra) Bar Barrington’s nu BIC nu brachium inf colliculus bic brachium inf colliculus Cb cerebellum CC central canal CCrus common crus CeAu cervicoauricular muscle chp choroid plexus CLi caudal linear nu raphe cp cerebral peduncle DC dorsal cochlear nu DLL dorsal nu lateral lemniscus DPGi dors paragigantocellular nu EGL external granular layer Cb ELS endolymphatic sac Fat loculated brown fat Gi gigantocellular reticular nu IC inferior colliculus icp inf cerebellar peduncle IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu lc lateral coumn spinal cord LC locus coeruleus LDTg laterodor tegmental nu LgsCa longissimus capitis muscle LPBE lat parabrachial nu, external LR4V lat recess 4th ventricle LRt lateral reticular nu MA3 med access oculomotor nu mcp middle cerebellar peduncle mlf med longitudinal fasciculus mPAG mesenc periaqueduc gray MVe medial vestibular nu Occ occipital bone occs occipital sinus PaR pararubral nu ParB parietal bone PCRt parvicell reticular nu pica post inferior Cb art Pr prepositus nu PSCC post semicircular canal PTg pedunculopontine tegmental RMC red nu, magnocell part ROb raphe obscurus nu RPa raphe pallidus nu RR retrorubral nu RRF retrorubral field SC superior colliculus scp superior Cb peduncle SN substantia nigra SObCa superior oblique Sol nu of solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SPTg subpeduncular tegmental nu SpVe spinal vestibular nu Su3 supraoculomotor PAG SubC subcoeruleus nu SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus TzM trapezius muscle vc ventral column spinal cord vert vertebral art VH ventral horn spinal cord VTg vent tegmental nu xscp decussation sup cereb ped

Figure 34 E17.5 #34 4.32 mm

SC mPAG

Aq

Me5 bic

ECIC BIC

Su3C Su3 3PC 3N

PrCnF

PBG

CLi

mlf

MiTg RRF/A8 DLL

ParB

scp PTg

LPB

PMnR

MPB

mcp EGL

LDTg scp

trs

LR4V chp

ASCC TempP

Bar

me5 SuVe Me5

Cb

ELS

CCrus

DTg

DC 8n icp

SpVe

X

occs sp5

Sol

5Sol PCRt

rs

Occ

MVe

Pr

Sp5I

SplCa SObCa

4V

sl

sol PSCC

IRt

mlf

Gi Amb LRt IOD

ROb

IOM

Atlas CeAu

VTg

LC

RPa

TzM Fat

IObCa

vc

LgsCa Axis VH Scap

lc CC Fat

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular 4V 4th ventricle 5Sol trigeminal-solitary trans 8n vestibulocochlear nerve Amb ambiguus nu Aq aqueduct ASCC anterior semicirc canal Atlas atlas Axis axis (C2 vertebra) Bar Barrington’s nu BIC nu brachium inf colliculus bic brachium inf colliculus Cb cerebellum CC central canal CCrus common crus CeAu cervicoauricular muscle chp choroid plexus CLi caudal linear nu raphe DC dorsal cochlear nu DLL dorsal nu lateral lemniscus DTg dorsal tegmental nu ECIC external cx inferior coll EGL external granular layer Cb ELS endolymphatic sac Fat loculated brown fat Gi gigantocellular reticular nu icp inf cerebellar peduncle IObCa inf oblique capitis IOD inf olive, dorsal nu IOM inf olive, med nu IRt intermed reticular nu LC locus coeruleus lc lateral coumn spinal cord LDTg laterodor tegmental nu LgsCa longissimus capitis muscle LPB lateral parabrachial nu LR4V lat recess 4th ventricle LRt lateral reticular nu mcp middle cerebellar peduncle Me5 mesencephalic trigem nu me5 mesencephalic trigem tract MiTg microcell tegmental nu mlf med longitudinal fasciculus mPAG mesenc periaqueduc gray MPB medial parabrachial nu MVe medial vestibular nu Occ occipital bone occs occipital sinus ParB parietal bone PBG parabigeminal nu PCRt parvicell reticular nu PMnR paramedian raphe nu Pr prepositus nu PrCnF precuneiform area PSCC post semicircular canal PTg pedunculopontine tegmental ROb raphe obscurus nu RPa raphe pallidus nu RRF/A8 retrorubral/A8 dopamine rs rubrospinal tract SC superior colliculus Scap scapula scp superior Cb peduncle sl sulcus limitans SObCa superior oblique Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SplCa splenius capitis muscle SpVe spinal vestibular nu Su3 supraoculomotor PAG Su3C supraoculomotor cap SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus TzM trapezius muscle vc ventral column spinal cord VH ventral horn spinal cord VTg vent tegmental nu X nu X

Figure 35 E17.5 #35 4.44 mm

SC Aq

bic

mPAG

ECIC BIC

CnF

DR

4N

MiTg

Pa4 mlf

DLL

DR mlf MPB

ParB

LDTg

LPB EGL

mcp Lat

trs

Bar

scp

DTg LC Me5

SuVe

4V

LR4V chp

chp SpVe

ELS

TempP

MVe 4V sol 10N 5Sol Sol Pr

X

icp CCrus occs

PCRt

Sp5I

sp5

12N

IRt SplCa

Gi

Occ

Amb

In

Ro ROb

MdV IOD IOM

LRt RCPMj pica

RPa

Atlas pyx

LgsCa 11N

DRGn CeAu

TzM

VH Fat Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

CC

lc

0.4

0.6

0.8

1.0 mm

4N trochlear nu 4V 4th ventricle 5Sol trigeminal-solitary trans 10N dorsal motor nu of vagus 11N accessory nerve nu 12N hypoglossal nu Amb ambiguus nu Aq aqueduct Atlas atlas Axis axis (C2 vertebra) Bar Barrington’s nu BIC nu brachium inf colliculus bic brachium inf colliculus CC central canal CCrus common crus CeAu cervicoauricular muscle chp choroid plexus CnF cuneiform nu DLL dorsal nu lateral lemniscus DR dorsal raphe nu DRGn dorsal root ganglion DTg dorsal tegmental nu ECIC external cx inferior coll EGL external granular layer Cb ELS endolymphatic sac Fat loculated brown fat Gi gigantocellular reticular nu icp inf cerebellar peduncle In intercalated nu medulla IOD inf olive, dorsal nu IOM inf olive, med nu IRt intermed reticular nu Lat lateral (dentate) Cb nu LC locus coeruleus lc lateral coumn spinal cord LDTg laterodor tegmental nu LgsCa longissimus capitis muscle LPB lateral parabrachial nu LR4V lat recess 4th ventricle LRt lateral reticular nu mcp middle cerebellar peduncle MdV medullary reticular nu, vent Me5 mesencephalic trigem nu MiTg microcell tegmental nu mlf med longitudinal fasciculus mPAG mesenc periaqueduc gray MPB medial parabrachial nu MVe medial vestibular nu Occ occipital bone occs occipital sinus Pa4 paratrochlear nu ParB parietal bone PCRt parvicell reticular nu pica post inferior Cb art Pr prepositus nu pyx pyramidal decussation RCPMj rectus capitis major Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu SC superior colliculus scp superior Cb peduncle Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SplCa splenius capitis muscle SpVe spinal vestibular nu SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus TzM trapezius muscle VH ventral horn spinal cord X nu X

Figure 36 E17.5 #36 4.56 mm

SC Aq bic

mPAG

IC

me5 CnF 4N

DR

Pa4

DLL

mlf PB mcp

ParB EGL Cb

scp

Lat

SuVe

4V

trs

chp LR4V

chp SpVe

TempP

4V

occs

5Sol Sol Sp5I

SplCa

MVe

10N In 12N

PCRt

Occ

IRt

Gi V ROb Amb MdV

RCPMj LRt

IOM pyx Atlas

LgsCa

CeAu

11N VH

Axis

TzM

CC

RCPMj Fat

lc

CV2

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4N trochlear nu 4V 4th ventricle 5Sol trigeminal-solitary trans 10N dorsal motor nu of vagus 11N accessory nerve nu 12N hypoglossal nu Amb ambiguus nu Aq aqueduct Atlas atlas Axis axis (C2 vertebra) bic brachium inf colliculus Cb cerebellum CC central canal CeAu cervicoauricular muscle chp choroid plexus CnF cuneiform nu CV2 second cervical vertebra DLL dorsal nu lateral lemniscus DR dorsal raphe nu EGL external granular layer Cb Fat loculated brown fat Gi gigantocellular reticular nu IC inferior colliculus IOM inf olive, med nu IRt intermed reticular nu lc lateral coumn spinal cord In intercalated nu medulla Lat lateral cerebellar nu LgsCa longissimus capitis muscle LR4V lat recess 4th ventricle LRt lateral reticular nu mcp middle cerebellar peduncle MdV medullary reticular nu, vent me5 mesencephalic trigem tract mlf med longitudinal fasciculus mPAG mesenc periaqueduc gray MVe medial vestibular nu Occ occipital bone occs occipital sinus Pa4 paratrochlear nu PaR pararubral nu ParB parietal bone PB parabrachial nucleus PCRt parvicell reticular nu pyx pyramidal decussation RCPMj rectus capitis major ROb raphe obscurus nu SC superior colliculus scp superior Cb peduncle Sol nu of solitary tract Sp5I spinal trigem nu, interpolar SplCa splenius capitis muscle SpVe spinal vestibular nu SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus TzM trapezius muscle VH ventral horn spinal cord

Figure 37 E17.5 #37 4.68 mm

SC

IC

Aq

CnF mPAG DLL

mcp Lat

Occ EGL

scp

IntA IntP

4V chp

LR4V

occs

chp SpVe

MVe

sol Sol sl 5Sol 10N In

BOcc

Sp5C

SplCa

sp5

4V

MdD 12N

12N

DRGn

LgsCa

11N

Atlas lc RCPMj

CeAu

CC

TzM

Axis

Fat

DH dcs

Fat

cu Scap

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

gr

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 10N dorsal motor nu of vagus 11N accessory nerve nu 12N hypoglossal nu Aq aqueduct Atlas atlas Axis axis (C2 vertebra) BOcc basioccipital bone CC central canal CeAu cervicoauricular muscle chp choroid plexus CnF cuneiform nu cu cuneate fasciculus dcs dors corticospinal tract DH dorsal horn spinal cord DLL dorsal nu lateral lemniscus DRGn dorsal root ganglion EGL external granular layer Cb Fat loculated brown fat gr gracile fasciculus IC inferior colliculus In intercalated nu medulla IntA interposed cerebellar nu, ant IntP interposed cerebellar nu, post Lat lateral (dentate) Cb nu lc lateral coumn spinal cord LgsCa longissimus capitis muscle LR4V lat recess 4th ventricle mcp middle cerebellar peduncle MdD medullary reticular nu, dors mPAG mesenc periaqueduc gray MVe medial vestibular nu Occ occipital bone occs occipital sinus RCPMj rectus capitis major SC superior colliculus Scap scapula scp superior Cb peduncle sl sulcus limitans Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal SplCa splenius capitis muscle SpVe spinal vestibular nu TzM trapezius muscle

Figure 38 E17.5 #38 4.80 mm

SC

Aq IC

mPAG

ParB CnF

cbx

ParB mcp EGL

IntA

Lat Cb

IntP 4V

LR4V occs SpVe

MVe

ECu 5Sol sol

Sol

BOcc sp5 Sp5C

SplCa

MdD

4V sl 10N In

12N

RCPMj

CeAu

Atlas

lc CC

LgsCa Fat Axis

DH dcs

Fat

cu gr

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solit trans 10N dorsal motor nu of vagus 12N hypoglossal nu Aq aqueduct Atlas atlas Axis axis (C2 vertebra) BOcc basioccipital bone Cb cerebellum cbx cerebellar commissure CC central canal CeAu cervicoauricular muscle CnF cuneiform nu cu cuneate fasciculus dcs dors corticospinal tract DH dorsal horn spinal cord ECu external cuneate nu EGL external granular layer Cb Fat loculated brown fat gr gracile fasciculus IC inferior colliculus In intercalated nu medulla IntA interposed cerebellar nu, ant IntP interposed cerebellar nu, post Lat lateral (dentate) Cb nu lc lateral coumn spinal cord LgsCa longissimus capitis muscle LR4V lat recess 4th ventricle mcp middle cerebellar peduncle MdD medullary reticular nu, dors mPAG mesenc periaqueduc gray MVe medial vestibular nu occs occipital sinus ParB parietal bone RCPMj rectus capitis major SC superior colliculus sl sulcus limitans Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal SplCa splenius capitis muscle SpVe spinal vestibular nu

Figure 39 E17.5 #39 4.92mm

SC

Aq IC

EGL

Cb

Lat

IntA

Med

SpVe

4V

ECu

Occ

AP

5Sol Sol sp5

SplCa

10N

Sp5C

RCPMj

LgsCa lc Atlas

TzM

DH

Fat Fat

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

Axis

0.6

0.8

dcs cu gr

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 10N dorsal motor nu of vagus AP area postrema Aq aqueduct Atlas atlas Axis axis (C2 vertebra) Cb cerebellum cu cuneate fasciculus dcs dors corticospinal tract DH dorsal horn spinal cord ECu external cuneate nu EGL external granular layer Cb Fat loculated brown fat gr gracile fasciculus IC inferior colliculus IntA interposed cerebellar nu, ant Lat lateral (dentate) Cb nu lc lateral coumn spinal cord LgsCa longissimus capitis muscle Med medial cerebellar nu Occ occipital bone RCPMj rectus capitis major SC superior colliculus Sol nu of solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal SplCa splenius capitis muscle SpVe spinal vestibular nu TzM trapezius muscle

Figure 40 E17.5 #40 5.04 mm

SC

Aq IC

Cb

EGL

4V ECu

Occ

5Sol sp5

Sp5C

sol Sol

AP

SplCa

LgsCa TzM

Atlas

RCPMj

DH

dcs

Fat cu Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

gr

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans AP area postrema Aq aqueduct Atlas atlas Axis axis (C2 vertebra) Cb cerebellum cu cuneate fasciculus dcs dors corticospinal tract DH dorsal horn spinal cord ECu external cuneate nu EGL external granular layer Cb Fat loculated brown fat gr gracile fasciculus IC inferior colliculus LgsCa longissimus capitis muscle Occ occipital bone RCPMj rectus capitis major SC superior colliculus Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal SplCa splenius capitis muscle TzM trapezius muscle

Figure 41 E17.5 #41 5.16 mm

SC

Aq

IC

Occ

4V ECu

Cu Sol

Sp5C

SplCa

MdD

sol

sp5

LgsCa TzM

Atlas

Fat

dcs RCPMj

DH cu gr

Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle Aq aqueduct Atlas atlas Axis axis (C2 vertebra) Cu cuneate nu cu cuneate fasciculus dcs dors corticospinal tract DH dorsal horn spinal cord ECu external cuneate nu Fat loculated brown fat gr gracile fasciculus IC inferior colliculus LgsCa longissimus capitis muscle MdD medullary reticular nu, dors Occ occipital bone RCPMj rectus capitis major SC superior colliculus Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal SplCa splenius capitis muscle TzM trapezius muscle

Figure 42 P0 #1 0.63 mm

EPl Gl Mi IPl GrO

Fro

ne

OV AOrb Eyelid

ON 1n

Pig

CrP

Eye EthB

NasC

Vent ne

InfM

NSpt 5mx Vom

MxB EnO

MasM

NasC

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division AOrb alar orbital bone CrP cribriform plate ethmoid EnO enamel organ EPl ext plexiform layer olf bulb EthB ethmoid bone Eye eye Eyelid eyelid Fro frontal bone Gl glomerular layer olf bulb GrO granular cell layer olf bulb InfM inferior meatus IPl IP layer olf bulb MasM masseter muscle Mi mitral cell layer olf bulb MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum ON olfactory nerve layer OV olfactory ventricle Pig pigment layer of the eye Vent ventricular space eye Vom vomer

Figure 43 P0 #2 0.75 mm

EPl Mi

Gl

Fro

IPl GrO

ne

AOrb

OV Vent

ON

Pig

EthB

InPl

RGn

1n

ne

CrP

NSpt

MidM

OF

Eye

HardG

NasC InfM 5mx

Vom EnO dpal

MasM

MxB Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division AOrb alar orbital bone CrP cribriform plate ethmoid dpal descending palatine artery EnO enamel organ EPl ext plexiform layer olf bulb EthB ethmoid bone Eye eye Fro frontal bone Gl glomerular layer olf bulb GrO granular cell layer olf bulb HardG Harderian gland InfM inferior meatus InPl inner plexiform layer IPl IP layer olf bulb MasM masseter muscle Mi mitral cell layer olf bulb MidM middle meatus MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer ON olfactory nerve layer Oral oral cavity OV olfactory ventricle Pig pigment layer of the eye RGn ganglion cell layer Vent ventricular space eye Vom vomer

Figure 44 P0 #3 0.87 mm

Fro Gl EPl

Mi IPl

ne

AOrb

OV

Vent 1n

EthB

RGn

Pig

CrP

ne

SupM MidM

Cornea

OF Vitr

InPl

NasC NSpt

InfM

HardG 5mx TempM

NasC dpal

MxB

EnO

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MasM

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division AOrb alar orbital bone Cornea cornea CrP cribriform plate ethmoid dpal descending palatine artery EnO enamel organ EPl ext plexiform layer olf bulb EthB ethmoid bone Fro frontal bone Gl glomerular layer olf bulb HardG Harderian gland InfM inferior meatus InPl inner plexiform layer IPl IP layer olf bulb MasM masseter muscle Mi mitral cell layer olf bulb MidM middle meatus MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer Oral oral cavity OV olfactory ventricle Pig pigment layer of the eye RGn ganglion cell layer SupM superior meatus TempM temporalis muscle Vent ventricular space eye Vitr vitreous cavity eye

Figure 45 P0 #4 0.99 mm

AOB

Fro

Gl

Mi IPl EPl

AOrb OV

Vent

InPl Cornea ne

Lens OF RGn

CrP

Iris

MidM NSpt NasC

InfM

5mx

HardG TempM

ZygA

NasC MxB Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MasM

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division AOB access olfactory bulb AOrb alar orbital bone Cornea cornea CrP cribriform plate ethmoid EPl ext plexiform layer olf bulb Fro frontal bone Gl glomerular layer olf bulb HardG Harderian gland InfM inferior meatus InPl inner plexiform layer IPl IP layer olf bulb Iris iris Lens lens MasM masseter muscle Mi mitral cell layer olf bulb MidM middle meatus MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer Oral oral cavity OV olfactory ventricle RGn ganglion cell layer TempM temporalis muscle Vent ventricular space eye ZygA zygomatic arch

Figure 46 P0 #5 1.11 mm

FrA

Fro

AOB Gl

SOb

Mi IPL

EPl

lo

ne

AOrb

OV

InPl

EPl

ON Vent CrP

Cornea

ne

Eth

OF RGn

MidM NasC NSpt 5mx NasC

HardG

ophv

TempM

ZygA

MxB Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MasM

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division AOB access olfactory bulb AOrb alar orbital bone Cornea cornea CrP cribriform plate ethmoid EPl ext plexiform layer olf bulb Eth ethmoid thalamic nu FrA frontal assocn cortex Fro frontal bone Gl glomerular layer olf bulb HardG Harderian gland InPl inner plexiform layer IPL interpedunc nu, lat subnu lo lateral olfactory tract MasM masseter muscle Mi mitral cell layer olf bulb MidM middle meatus MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer ON olfactory nerve layer ophv ophthalmic vein Oral oral cavity OV olfactory ventricle RGn ganglion cell layer SOb superior oblique muscle TempM temporalis muscle Vent ventricular space eye ZygA zygomatic arch

Figure 47 P0 #6 1.23 mm

FrA

Fro

AOrb

AOD

lo

AOM ne

OV AOL AOE

Cornea

GrO AOV

Lens Iris

MidM NasC NSpt 5mx NasC

HardG

EnO MxB

TempM

ZygA

MasM

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division AOD ant olfactory nu, dors AOE ant olfactory nu, ext AOL ant olfactory nu, lat AOM ant olfactory nu, medial AOrb alar orbital bone AOV ant olfactory nu, ventral Cornea cornea EnO enamel organ FrA frontal assocn cortex Fro frontal bone GrO granular cell layer olf bulb HardG Harderian gland Iris iris Lens lens lo lateral olfactory tract MasM masseter muscle MidM middle meatus MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum Oral oral cavity OV olfactory ventricle TempM temporalis muscle ZygA zygomatic arch

Figure 48 P0 #7 1.35 mm

M2 Fro

PrL MO

VO

AOM DTT

DLO

LO AOD ne OV

lo

AOL

AOVP VTT

Eye MidM

NasC NSpt NasC

5mx Pal

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division AOD ant olfactory nu, dors AOL ant olfactory nu, lat AOM ant olfactory nu, medial AOVP ant olfactory, ventropost DLO dorsolat orbital cortex DTT dorsal tenia tecta Eye eye Fro frontal bone LO lateral orbital cx lo lateral olfactory tract M2 secondary motor cx MidM middle meatus MO medial orbital cx NasC nasal cavity ne neuroepithelium NSpt nasal septum Oral oral cavity OV olfactory ventricle Pal palatine bone PrL prelimbic cx VO ventral orbital cx VTT ventral tenia tecta

Figure 49 P0 #8 1.47mm

M2

Cg2

M1 Fro

PrL LO

VO

DLO

MO AOD AOM

ne

OV

DTT

AOVP VTT

AOL Pir aca

lo

AOP AOrb ne

CrP

LPS

InPl

OF

Eye

RGn

SRec

MidM NasC NSpt

MRec 5mx

NasC

Pal

HardG

EnO

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

TempM

ZygA MasM

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division aca anterior commissure, ant AOD ant olfactory nu, dors AOL ant olfactory nu, lat AOM ant olfactory nu, medial AOP ant olfactory nu, post AOrb alar orbital bone AOVP ant olfactory, ventropost Cg2 cingulate cortex, area 2 CrP cribriform plate ethmoid DLO dorsolat orbital cortex DTT dorsal tenia tecta EnO enamel organ Eye eye Fro frontal bone HardG Harderian gland InPl inner plexiform layer lo lateral olfactory tract LO lateral orbital cx LPS levator palpebrae M1 primary motor cx M2 secondary motor cx MasM masseter muscle MidM middle meatus MO medial orbital cx MRec medial rectus muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer Oral oral cavity OV olfactory ventricle Pal palatine bone Pir piriform cortex PrL prelimbic cx RGn ganglion cell layer SRec superior rectus muscle TempM temporalis muscle VO ventral orbital cx VTT ventral tenia tecta ZygA zygomatic arch

Figure 50 P0 #9 1.59 mm

M2

Cg1

M1 PrL

Fr3 fmi

AID AIV

IL Cl

DP DTT

LO

ne OV

SHi

Fro

DEn

aca IEn

Pir

LSI AOVP AOP Nv Tu

lo

Lens ne InPl

OF RGn

MidM NasC NSpt

5mx iorb

HardG

Pal

TempM

ZygA MasM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division aca anterior commissure, ant AID agranular insular cx, dorsal AIV agranular insular cx, vent AOP ant olfactory nu, post AOVP ant olfactory, ventropost Cg1 cingulate cortex, area 1 Cl claustrum DEn dorsal endopiriform nu DP dorsal peduncular cx DTT dorsal tenia tecta fmi forceps min corpus call Fr3 frontal cx, area 3 Fro frontal bone HardG Harderian gland IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer iorb infraorbital artery Lens lens lo lateral olfactory tract LO lateral orbital cx LSI lat septal nu, intermed M1 primary motor cx M2 secondary motor cx MasM masseter muscle MidM middle meatus NasC nasal cavity ne neuroepithelium NSpt nasal septum Nv navicular nu basal forebrain OF optic fiber layer OV olfactory ventricle Pal palatine bone Pir piriform cortex PrL prelimbic cx RGn ganglion cell layer SHi septohippocampal nu TempM temporalis muscle Tu olfactory tubercle ZygA zygomatic arch

Figure 51 P0 #10 1.71mm

M2

Cg1

M1 PrL fmi

Fr3

IL

dcw

S1J

DP Cl LO

DTT

ne

LV

Pir

aca Acb

Nv

lo

DEn

SHi LSI

AID AIV

LPS

IEn

Vent ne

Tu

InPl

Lens OF RGn

OpD

SRec NasC IRec 5mx NasC Pal

HardG

iorb

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

ZygA

0

0.2

0.4

0.6

0.8

1.0 mm

5mx 5n, maxillary division aca anterior commissure, ant Acb accumbens nu AID agranular insular cx, dorsal AIV agranular insular cx, vent Cg1 cingulate cortex, area 1 Cl claustrum dcw deep cerebral white DEn dorsal endopiriform nu DP dorsal peduncular cx DTT dorsal tenia tecta fmi forceps min corpus call Fr3 frontal cx, area 3 HardG Harderian gland IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer iorb infraorbital artery IRec inferior rectus muscle Lens lens LO lateral orbital cx lo lateral olfactory tract LPS levator palpebrae LSI lat septal nu, intermed LV lateral ventricle M1 primary motor cx M2 secondary motor cx NasC nasal cavity ne neuroepithelium Nv navicular nu basal forebrain OF optic fiber layer OpD optic disc Pal palatine bone Pir piriform cortex PrL prelimbic cx RGn ganglion cell layer S1J prim somatosens, jaw SHi septohippocampal nu SRec superior rectus muscle Tu olfactory tubercle Vent ventricular space eye ZygA zygomatic arch

Figure 52 P0 #11 1.83 mm

M2 Cg1

M1 Fr3

PrL fmi

IL DP

Fro

S1J dcw

DTT

ne Cl

LV

SHi

DI AID AIV

CPu

LPS

rf

DEn

Nv LSI aca IEn

Pir

lo

Acb

SRec

VDB VP Tu

Vitr AOrb

Vent

ne

OF RGn

NasC

2n InPl

NSpt SphPal

5mx

NasC

HardG

Pal Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 5mx 5n, maxillary division aca anterior commissure, ant Acb accumbens nu AID agranular insular cx, dorsal AIV agranular insular cx, vent AOrb alar orbital bone Cg1 cingulate cortex, area 1 Cl claustrum CPu caudate putamen (striatum) dcw deep cerebral white DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTT dorsal tenia tecta fmi forceps min corpus call Fr3 frontal cx, area 3 Fro frontal bone HardG Harderian gland IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer lo lateral olfactory tract LPS levator palpebrae LSI lat septal nu, intermed LV lateral ventricle M1 primary motor cx M2 secondary motor cx NasC nasal cavity ne neuroepithelium NSpt nasal septum Nv navicular nu basal forebrain OF optic fiber layer Oral oral cavity Pal palatine bone Pir piriform cortex PrL prelimbic cx rf rhinal fissure RGn ganglion cell layer S1J prim somatosens, jaw SHi septohippocampal nu SphPal sphenopalatine ganglion SRec superior rectus muscle Tu olfactory tubercle VDB nu vertical limb diagonal band Vent ventricular space eye Vitr vitreous cavity eye VP ventral pallidum

Figure 53 P0 #12 1.95 mm

M2

Cg1

M1

PrL IL DP

S1J

fmi

DTT

DI

LV

ec

AID

Cl

SHi LSD

CPu

AIV

LSV LSI

rf Eyelid

DEn

ne

MS

Pir

aca Acb IEn AcbSh CB VP VP VP

OF

PSphW

VDB

InPl

SRec AOrb

RGn

ne Eye 2n

SphPal 5mx iorb

IOrbF

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

HardG

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 5mx 5n, maxillary division aca ant commiss ant limb Acb accumbens nu AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent AOrb alar orbital bone CB cell bridges vent striatum Cg1 cingulate cortex, area 1 Cl claustrum CPu caudate putamen (striatum) DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTT dorsal tenia tecta ec external capsule Eye eye Eyelid eyelid fmi forceps min corpus call HardG Harderian gland IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer iorb infraorbital artery IOrbF infraorbital foramen LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx MS medial septal nu ne neuroepithelium OF optic fiber layer Pir piriform cortex PrL prelimbic cx PSphW presphenoid wing rf rhinal fissure RGn ganglion cell layer S1J prim somatosens, jaw SHi septohippocampal nu SphPal sphenopalatine ganglion SRec superior rectus muscle VDB nu vertical limb diagonal band VP ventral pallidum

Figure 54 P0 #13 2.07 mm

Cg1

M2 M1 cg

Cg2

S1J IG gcc DTT

ec Fro

LV GI

LSD

SHi

CPu

DI

Cl LSV

LSI

AID

ne

AIV DEn

MS

aca

ICjM

Pir

AcbC

LSS IEn CB

AcbSh VDB

Pig

PSphW Vent

VP

SIB HDB

lo

AOrb SRec

Tu

ne Eye

2n PSph

LRec

MRec IRec SphPal

NasC

5mx iorb

TempM ZygA Man

Oral MasM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 5mx 5n, maxillary division aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent AOrb alar orbital bone CB cell bridges vent striatum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cl claustrum CPu caudate putamen (striatum) DEn dorsal endopiriform nu DI dysgranular insular cx DTT dorsal tenia tecta ec external capsule Eye eye Fro frontal bone gcc genu corpus callosum GI granular insular cx HDB nu horizlimb diagonal band ICjM islands of Calleja, major IEn intermed endopiriform nu IG indusium griseum iorb infraorbital artery IRec inferior rectus muscle lo lateral olfactory tract LRec lat rectus muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MRec medial rectus muscle MS medial septal nu NasC nasal cavity ne neuroepithelium Oral oral cavity Pig pigment layer of the eye Pir piriform cortex PSph presphenoid bone PSphW presphenoid wing S1J prim somatosens, jaw SHi septohippocampal nu SIB substantia innominata, basal SphPal sphenopalatine ganglion SRec superior rectus muscle TempM temporalis muscle Tu olfactory tubercle VDB nu vertical limb diagonal band Vent ventricular space eye VP ventral pallidum ZygA zygomatic arch

Figure 55 P0 #14 2.19 mm

M2

Cg1

M1 S1FL

cg

Cg2

S1DZ S1J ne

IG

ec

LV

Fro

DTT LSD Cl

SHi CPu LSI

GI DI AID AIV

DEn

LSV

rf

MS IEn

Pir

aca AcbC VDB

HDB

lo ICj

VP

AcbSh SIB

LSS

Pig

VP CB

VP

PSphW

Tu SRec

acer 2n PSph

OptF

LRec

MRec IRec

SphPal 5mx

TempM

NasC

Cor TempM

Pal

ZygA

Man Oral

MxB MasM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 5mx 5n, maxillary division aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent CB cell bridges vent striatum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) DEn dorsal endopiriform nu DI dysgranular insular cx DTT dorsal tenia tecta ec external capsule Fro frontal bone GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum IRec inferior rectus muscle lo lateral olfactory tract LRec lat rectus muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MRec medial rectus muscle MS medial septal nu MxB maxillary bone NasC nasal cavity ne neuroepithelium OptF optic foramen Oral oral cavity Pal palatine bone Pig pigment layer of the eye Pir piriform cortex PSph presphenoid bone PSphW presphenoid wing rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw SHi septohippocampal nu SIB substantia innominata, basal SphPal sphenopalatine ganglion SRec superior rectus muscle TempM temporalis muscle Tu olfactory tubercle VDB nu vertical limb diagonal band VP ventral pallidum ZygA zygomatic arch

Figure 56 P0 #15 2.31 mm

Cg1

M2 M1 cg

Cg2

S1FL S1DZ

dcw

IG

S1J

gcc

LV LSD

SHi

Fro

ec LSI CPu

LSV ne

Cl

PLd MS

DEn ac

AcbSh

LSS IEn

AcbC VDB

VP HDB

lo

PSphW ICj Tu

acer

SRec

2n PSph

3 2Pir 1

LAcbSh CB ICj mfb VP

SIB

TempM LRec

OptF SphPal

IRec Cor

5mx

NasC

iorb

Pal

Oral

GI DI AID AIV rf

ZygA MxB

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Man MasM

0

0.2

0.4

0.6

0.8

1.0 mm

1 layer 1 of cortex 2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division ac anterior commissure AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent CB cell bridges vent striatum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) dcw deep cerebral white DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule Fro frontal bone gcc genu corpus callosum GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum iorb infraorbital artery IRec inferior rectus muscle LAcbSh lateral accumbens shell lo lateral olfactory tract LRec lat rectus muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle mfb med forebrain bundle MS medial septal nu MxB maxillary bone NasC nasal cavity ne neuroepithelium OptF optic foramen Oral oral cavity Pal palatine bone Pir piriform cortex PLd paralambdoid septal nu PSph presphenoid bone PSphW presphenoid wing rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw SHi septohippocampal nu SIB substantia innominata, basal SphPal sphenopalatine ganglion SRec superior rectus muscle TempM temporalis muscle Tu olfactory tubercle VDB nu vertical limb diagonal band VP ventral pallidum ZygA zygomatic arch

Figure 57 P0 #16 2.43 mm

M2

Cg1

M1 S1FL S1DZ

cg

Cg2 IG

ne

S1J

LV

cc

ec

LSD

SHi Ld

LSI CPu

PLd

Cl

LSV

GI DI AID

Fro

AIV rf

MS

DEn ac AcbSh

VDB

SIB HDB

IEn AcbC LAcbSh ICj

VP Tu

TempM PSphW

2n LRec

PSph SphPal NasC

Pir 3 2 1 lo

Pal

Cor

5mx iorb

Man ZygA

Oral MasM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1 layer 1 of cortex 2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division ac anterior commissure AcbC accumbens nu, core AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule Fro frontal bone GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum iorb infraorbital artery LAcbSh lateral accumbens shell Ld lambdoid septal zone lo lateral olfactory tract LRec lat rectus muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MS medial septal nu NasC nasal cavity ne neuroepithelium Oral oral cavity Pal palatine bone Pir piriform cortex PLd paralambdoid septal nu PSph presphenoid bone PSphW presphenoid wing rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw SHi septohippocampal nu SIB substantia innominata, basal SphPal sphenopalatine ganglion TempM temporalis muscle Tu olfactory tubercle VDB nu vertical limb diagonal band VP ventral pallidum ZygA zygomatic arch

Figure 58 P0 #17 2.55 mm

M2

Cg1

M1 S1FL

cg

Cg2

S1DZ

IG

S1J

LV ne

cc

ec

LSD

SHi

GI DI

Cl LSI MS

CPu DEn

LSV

SFi

AID AIV

rf

IEn STMA

ZL SHy

MnPO

Fro

Pir

AcbC

ac AcbSh

IPAC

lo

LSS ICj

VOLT

LPO

VP

TempM

MPA SIB Tu AVPe

HDB

MCPO

ICj ASph

2n

VMPO

LPtg Cor

PSph

ptgpal SphPal

5mx

TempM

iorb

NasC

ZygA

Pal Man Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MasM

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 5mx 5n, maxillary division ac anterior commissure AcbC accumbens nu, core AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent ASph alisphenoid bone AVPe ant ventral periventric nu cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule Fro frontal bone GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum iorb infraorbital artery IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MCPO magnocell preoptic nu MnPO median preoptic nu MPA medial preoptic area MS medial septal nu NasC nasal cavity ne neuroepithelium Oral oral cavity Pal palatine bone Pir piriform cortex PSph presphenoid bone ptgpal pterygopalatine n rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw SFi septofimbrial nu SHi septohippocampal nu SHy septohypothalamic nu SIB substantia innominata, basal SphPal sphenopalatine ganglion STMA bed nu st, med div, ant TempM temporalis muscle Tu olfactory tubercle VMPO ventmed preoptic nu VOLT vasc organ lam ter VP ventral pallidum ZL zona limitans ZygA zygomatic arch

Figure 59 P0 #18 2.67 mm

M1

M2

S1FL

Cg1

S1DZ

S1J

cg Cg2

S1DZO

IG

LV

cc

LSI

SFi

f

3V

ac

LTer

STLP

STMV Al MPOL

STLJ

IPAC

Fu

PS

MPA VLPO AVPe

IEn

STLV

VP

LPO

PSph

DEn

acp

StA

VMPO

AIV

GP

SHy

3V

Cl

STLD

SHy STMA

GI DI AID

CPu

LSV LTer

S1ULp

ec

LSD

LSS

3 2 Pir 1 lo CxA ICj

CB

TempM

SIB Tu HDB

MCPO

2n 5oph SphPal cav

6n 5mx

ASph 3n 4n

Cor LPtg

ZygA ptgpal

Pal Man MasM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1 layer 1 of cortex 2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve ac anterior commissure acp anterior comm, posterior AID agranular insular cx, dorsal AIV agranular insular cx, vent Al alar nu ASph alisphenoid bone AVPe ant ventral periventric nu cav cavernous sinus CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cl claustrum Cor coronoid process mandible CPu caudate putamen (striatum) CxA cortex-amyg transition DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule f fornix Fu bed nu st, fusiform GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LTer lemina terminalis LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MCPO magnocell preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral Pal palatine bone Pir piriform cortex PS parastrial nu PSph presphenoid bone ptgpal pterygopalatine n S1DZ prim somatosens, dysgranul S1DZO prim somatosens, oral dysg S1FL prim somatosens, forelimb S1J prim somatosens, jaw S1ULp prim somatosens, upper lip SFi septofimbrial nu SHy septohypothalamic nu SIB substantia innominata, basal SphPal sphenopalatine ganglion StA strial part preoptic area STLD bed nu st, lat div, dorsal STLJ bed nu st, lat div, juxtacap STLP bed nu st, lat div, posterior STLV bed nu st, lat div, ventral STMA bed nu st, med div, ant STMV bed nu st, med div, ventral TempM temporalis muscle Tu olfactory tubercle VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum ZygA zygomatic arch

Figure 60 P0 #19 2.79 mm

M2

Cg1

M1 S1FL

cg

Cg2

S1DZ

IG

LV

S1ULp

ne

cc LSD ec LSI

SFi

S2

STLD

GI DI AID AIV rf

TS LSV

VCl

SHy

f

STMA STLP

LTer ac

DCl

CPu

ic

DEn

Pir

STLJ

STMV

Fro

IEn STLV

SHy

StA PS Al

3V

AVPe

LSS

MPOM VP MPA LPO MPOL SIB

VLPO 2n VMPO PSph

lo

IPAC

Fu

HDB

CxA TempM Tu

MCPO 6n

LPtg 3n 4n ASph 5oph 5mx

NasC Pal

ZygA Man

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MasM

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve ac anterior commissure AID agranular insular cx, dorsal AIV agranular insular cx, vent Al alar nu ASph alisphenoid bone AVPe ant ventral periventric nu cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) CxA cortex-amyg transition DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule f fornix Fro frontal bone Fu bed nu st, fusiform GI granular insular cx HDB nu horizlimb diagonal band ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LTer lemina terminalis LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MCPO magnocell preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial NasC nasal cavity ne neuroepithelium Oral oral cavity Pal palatine bone Pir piriform cortex PS parastrial nu PSph presphenoid bone rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SHy septohypothalamic nu SIB substantia innominata, basal StA strial part preoptic area STLD bed nu st, lat div, dorsal STLJ bed nu st, lat div, juxtacap STLP bed nu st, lat div, posterior STLV bed nu st, lat div, ventral STMA bed nu st, med div, ant STMV bed nu st, med div, ventral TempM temporalis muscle TS triangular septal nu Tu olfactory tubercle VCl vent part claustrum VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum ZygA zygomatic arch

Figure 61 P0 #20 2.91 mm

M1

M2

Cg1

S1FL S1DZ

cg

Cg2 IG cc

S1ULp

LV LSD

ec

GI TS

LSI

SFi

DCl CPu

SHy

LTer

ic

STMPM STMPL STMPI BAC STLP

f

STLI PaAP

Pir IPAC

StHy

LSS

VP

PDPO

MPOL

3V VMPO PSph

SIB

LPO

MCPO

CxA2 ASph

MPA VLPO 2n

Cor

Tu

HDB

LPtg acer

6n

3n

cav NasC

lo TempM

MPOM

Pe

rf

DEn acp

ac

DI AID VCl AIV

SphPal Pal

5mx

4n ptgpal

ZygA Man

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MasM

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 6n root of abducens nerve ac anterior commissure acer anterior cerebral art acp anterior comm, posterior AID agranular insular cx, dorsal AIV agranular insular cx, vent ASph alisphenoid bone BAC bed nu ant commissure cav cavernous sinus cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 Cor coronoid process mandible CPu caudate putamen (striatum) CxA2 cortex-amyg trans, lr 2 DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule f fornix GI granular insular cx HDB nu horizlimb diagonal band ic internal capsule IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LTer lemina terminalis LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MasM masseter muscle MCPO magnocell preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial NasC nasal cavity Oral oral cavity PaAP paraventric hy, ant parvicell Pal palatine bone PDPO posterodorsal preoptic nu Pe periventricular hypothal nu Pir piriform cortex PSph presphenoid bone ptgpal pterygopalatine n rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1ULp prim somatosens, upper lip SFi septofimbrial nu SHy septohypothalamic nu SIB substantia innominata, basal SphPal sphenopalatine ganglion StHy striohypothalamic nu STLI bed nu st, lat div, intermed STLP bed nu st, lat div, posterior STMPI bed nu st, med div, postint STMPL bed nu st, med div, post lat STMPM bed nu st, med div, post med TempM temporalis muscle TS triangular septal nu Tu olfactory tubercle VCl vent part claustrum VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum ZygA zygomatic arch

Figure 62 P0 #21 3.03 mm

M2

M1

Cg1

S1HL

Cg1

cc df

S1FL

cg

S1DZ S1BF

IG LV LSD

ec

S1ULp

SFi TS vhc SFO

S2

fi ne

DCl IVF st

ic

PL

P

GP

IEn

f

PaAP

LPO

MPA

VMPO PSph

MCPO HDB

VLPO 2n

4n

6n 3n cav

NasC

Tu

SIB

MPOM MPOL

3V

lo CxA

LSS

VP

PDPO

MPOC

Pir

IPAC StHy

Pe

rf

DEn STL

BAC

APF 3V

STM P STM M PI

sm PT

CPu

STM

3V PVA

GI DI AID VCl AIV

ASph

LPtg

5oph 5mx

ptgpal

SphPal Man

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve AID agranular insular cx, dorsal AIV agranular insular cx, vent APF anterior perifornical nu ASph alisphenoid bone BAC bed nu ant commissure cav cavernous sinus cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 CPu caudate putamen (striatum) CxA cortex-amyg transition DCl dors part of claustrum DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx ec external capsule f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac IVF interventricular foramen lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LSD lat septal nu, dorsal part LSS lat stripe striatum LV lateral ventricle M1 primary motor cx M2 secondary motor cx Man mandible MCPO magnocell preoptic nu MPA medial preoptic area MPOC medial preoptic nu, central MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial NasC nasal cavity ne neuroepithelium Oral oral cavity PaAP paraventric hy, ant parvicell PDPO posterodorsal preoptic nu Pe periventricular hypothal nu Pir piriform cortex PSph presphenoid bone PT paratenial thalamic nu ptgpal pterygopalatine n PVA paraventricular thal nu, ant rf rhinal fissure S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip SFi septofimbrial nu SFO subfornical organ SIB substantia innominata, basal sm stria medullaris thal SphPal sphenopalatine ganglion st stria terminalis StHy striohypothalamic nu STLP bed nu st, lat div, posterior STMPI bed nu st, med div, postint STMPL bed nu st, med div, post lat STMPM bed nu st, med div, post med TS triangular septal nu Tu olfactory tubercle VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum

Figure 63 P0 #22 3.15 mm

M2

M1

RSD

S1HL S1FL

cg

RSGc

S1DZ S1BF

IG df

LV

S1ULp

Or

CA3

vhc

ne

S2 3V

PVA CM

fi

IVF

RtSt CPu STMPL

sm AD PT PC

st

VCl

ic

rf

AVVL AVDM

IAD AM

DEn

Rt

Re PaXi

GP

IEn

sm B

SM

3V PaAP

f STMP

IPAC VP

EA

Tu

SIB

Pe MPOL LPO

HDB

MCPO AA

VLPO

PSph SphPal

mcer

ASph 6n

4n

3n

ZygA

LPtg Cond

5n NasC

TempM

lo

CxA

MPOM

VMPO 2n

Pir

acp

StHy

MPA

GI DI AID AIV

DCl

ptgpal MasM

Oral ialn

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2n optic nerve 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5n trigeminal nerve 6n root of abducens nerve AA anterior amyg area acp anterior comm, posterior AD anterodorsal thalamic nu AID agranular insular cx, dorsal AIV agranular insular cx, vent AM anteromedial thalamic nu ASph alisphenoid bone AVDM ant vent thal nu, dorsomed AVVL ant ventral thal, ventrolat B basal nu (Meynert) cg cingulum CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) CxA cortex-amyg transition DCl dors part of claustrum DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx EA sublenticular extend amyg f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band IAD interanterodorsal thal nu ialn inferior alveolar nerve ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac IVF interventricular foramen lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LV lateral ventricle M1 primary motor cx M2 secondary motor cx MasM masseter muscle mcer middle cerebral artery MCPO magnocell preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial NasC nasal cavity ne neuroepithelium Or oriens layer hippocampus Oral oral cavity PaAP paraventric hy, ant parvicell PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir piriform cortex PSph presphenoid bone PT paratenial thalamic nu ptgpal pterygopalatine n PVA paraventricular thal nu, ant Re reuniens thalamic nu rf rhinal fissure RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, up lip S2 2ary somatosensory cx SIB substantia innominata, basal SM nu stria medullaris sm stria medullaris thal SphPal sphenopalatine ganglion st stria terminalis StHy striohypothalamic nu STMP bed nu st, med div, post STMPL bed nu st, med div, post lat TempM temporalis muscle Tu olfactory tubercle VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum ZygA zygomatic arch

Figure 64 P0 #23 3.27 mm

M2

M1

RSD

S1HL S1FL

cg

RSGc

S1DZ dcw

S1BF

cc LV ne

dhc

CA3

S1ULp

ec

DG MHb LHb sm AD MD PC

PVA

AVDM

PT CM

CPu

AVVL

RtSt

VCl

st ic GP

IEn

Xi PaMP PaMM SPa PaV

3

B

sm ANS SM

PaXi

acp

EAC

STMP

MPOM

Pe MPOL MPA

LPO

VP

3

SIB

2

ACo

TempM

lo CxA1

MCPO AA HDB

VMPO

och SCh sox PSph

2 Pir 1

LSS

IPAC

f StHy

3V

rf

DEn

Rt

VRe

GI DI AID AIV

DCl

IAD AM

Re

S2

fi

ASph

VLPO SphPal

6n 3n 5oph 5mx

ZygA

LPtg

4n ptgpal

Cond MasM

Pal MPtg

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve AA anterior amyg area ACo ant cortical amygdaloid nu acp anterior comm, posterior AD anterodorsal thalamic nu AID agranular insular cx, dorsal AIV agranular insular cx, vent AM anteromedial thalamic nu ANS access neurosecretory nu ASph alisphenoid bone AVDM ant vent thal nu, dorsomed AVVL ant ventral thal, ventrolat B basal nu (Meynert) cc corpus callosum cg cingulum CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) CxA1 cortex-amyg trans, lr 1 DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu DG dentate gyrus dhc dorsal hippocampal comm DI dysgranular insular cx EAC sublent extend amyg, cent ec external capsule f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band IAD interanterodorsal thal nu ic internal capsule IEn intermed endopiriform nu IPAC interst nu post limb ac LHb lateral habenular nu lo lateral olfactory tract LPO lat preoptic area LPtg lat pterygoid muscle LV lateral ventricle M1 primary motor cx M2 secondary motor cx MasM masseter muscle MCPO magnocell preoptic nu MD mediodorsal thalamic nu MHb med habenular nu MPA medial preoptic area MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial MPtg medial pterygoid muscle ne neuroepithelium och optic chiasm Pal palatine bone PaMM paravent hy, med magnocel PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir piriform cortex PSph presphenoid bone PT paratenial thalamic nu ptgpal pterygopalatine n PVA paraventricular thal nu, ant Re reuniens thalamic nu rf rhinal fissure RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, up lip S2 2ary somatosensory cx SCh suprachiasmatic nu SIB substantia innominata, basal SM nu stria medullaris sm stria medullaris thal sox supraoptic decussation SPa subparaventric zone hy SphPal sphenopalatine ganglion st stria terminalis StHy striohypothalamic nu STMP bed nu st, med div, post Refer to Index of Abbreviations for other entries

Figure 65 P0 #24 3.39 mm

RSD RSGc

M2

M1

S1HL

S1FL

cg

S1DZ S1BF

dcw

ne cc FC

LV

CA1

S1ULp

CA2 CA3

hif

ec CPu

DG

S2

fi

sm MHb LD LHb PVA CL AV VL MD IMD RtSt AngT CM AM Rh IAM mt VA eml

Xi

Re VRe

PaXi A13

SCh

ic

DEn

GP

acp

IPAC

CeM

3

3 2 CxA1 ACo

MCPO

PLH

HDB

LOT2

AA

VLH

ZygA

ESO 6n

SO

Pir1 TempM

BMA

LA

BSph SphPal

2

VEn

EAC

EAM

och sox

NasC

AIV rf

JPLH

PaMM SPa PaV AHA

Pe

AID

I

JPLH f

3V

DI

VCl

ZIR

PaLM ANS

PaMP

st

Rt

VM

GI

DCl

LPtg ptgpal

5Gn/5n Pal

ialn

MasM

MPtg Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Mc

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5Gn/5n trigem ganglion and nerve 6n root of abducens nerve AA anterior amyg area ACo ant cortical amygdaloid nu acp anterior comm, posterior AHA anterior hypothal area, ant AID agranular insular cx, dorsal AIV agranular insular cx, vent AM anteromedial thalamic nu AngT angular thalamic nu ANS access neurosecretory nu AV anteroventral thalamic nu BMA basomed amyg nu, ant BSph basisphenoid bone cc corpus callosum CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) CxA1 cortex-amyg trans, lr 1 DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu DG dentate gyrus DI dysgranular insular cx EAC sublent extend amyg, cent EAM sublent extended amyg, med ec external capsule eml external medullary lamina ESO episupraoptic nu f fornix FC fasciola cinereum fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band hif hippocampal fissure I intercalated nuclei amyg ialn inferior alveolar nerve IAM interanteromedthal nu ic internal capsule IMD intermediodorsal thal nu IPAC interst nu post limb ac JPLH juxtaparaventricular lat hy LA lateroanterior hypothal nu LD laterodorsal thal nu LHb lateral habenular nu LOT2 nu lat olf tract, layer 2 LPtg lat pterygoid muscle LV lateral ventricle M1 primary motor cx M2 secondary motor cx MasM masseter muscle Mc Meckel’s cartilage MCPO magnocell preoptic nu MD mediodorsal thalamic nu MHb med habenular nu MPtg medial pterygoid muscle mt mammillothalamic tract NasC nasal cavity ne neuroepithelium och optic chiasm Oral oral cavity Pal palatine bone PaLM paravent hy, lat magnocell PaMM paravent hy, med magnocel PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thalamic nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy ptgpal pterygopalatine n PVA paraventricular thal nu, ant Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, up lip S2 2ary somatosensory cx SCh suprachiasmatic nu sm stria medullaris thal Refer to Index of Abbreviations for other entries

Figure 66 P0 #25 3.51 mm

M2

RSD

M1

S1HL S1Sh S1DZ

cg

RSGc

S1BF

dcw scc

dhc

FC D3V

CA2

CA1

S1ULp

sm

MHb LHb PV

S2

fi LD

CL

VM

ic

PaMP

PaLM JPLH SPa

B

AH Pe

PaV

MCPO HDB

AHC SChDL

2

Pir1

VEn TempS TempM

BMA

CxA

3 ACo

MeAD

VLH ESO

LA

2 ASph

LOT1

ZygA

SO

SChVM

sox

AA

PLH

3

acp

EAC CeM ANS EAM f

rf

DEn

Rt

mt

ZIR

3V

VCl

VPL

Re PaXi

CPu

st

VL

AM Sub

Rh

RtSt PC

IMD CM IAM

GI DI AID AIV

DCl

MDL MDM

Xi

ec

CA3

DG

opt

Cond LPtg

BSph 5Gn NasC Ptg MPtg

Mc

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5Gn trigeminal ganglion AA anterior amyg area ACo ant cortical amygdaloid nu acp anterior comm, posterior AH anterior hypothalamic area AHC anterior hy area, central AID agranular insular cx, dorsal AIV agranular insular cx, vent AM anteromedial thalamic nu ANS access neurosecretory nu ASph alisphenoid bone B basal nu (Meynert) BMA basomed amyg nu, ant BSph basisphenoid bone CeM central amyg nu, med div cg cingulum CL centrolateral thalamic nu CM centromedian thalamic nu Cond condylar process mandible CPu caudate putamen (striatum) CxA cortex-amyg transition D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu DG dentate gyrus dhc dorsal hippocampal comm DI dysgranular insular cx EAC sublent extend amyg, cent EAM sublent extended amyg, med ec external capsule ESO episupraoptic nu f fornix FC fasciola cinereum fi fimbria hippocampus GI granular insular cx HDB nu horizlimb diagonal band IAM interanteromedthal nu ic internal capsule IMD intermediodorsal thal nu JPLH juxtaparaventricular lat hy LA lateroanterior hypothal nu LD laterodorsal thal nu LHb lateral habenular nu LOT1 nu lat olf tract, layer 1 LPtg lat pterygoid muscle LSS lateral striatal stripe M1 primary motor cx M2 secondary motor cx Mc Meckel’s cartilage MCPO magnocell preoptic nu MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MHb med habenular nu MPtg medial pterygoid muscle mt mammillothalamic tract NasC nasal cavity opt optic tract Oral oral cavity PaLM paravent hy, lat magnocell PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thalamic nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy Ptg pterygoid proces sphenoid PV paraventricular thalamic nu Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1HL prim somatosens, hindlimb S1Sh prim somatosens, shoulder S1ULp prim somatosens, upper lip S2 2ary somatosensory cx scc splenium corpus callosum SChDL suprachiasmatic, dorsolat SChVM suprachiasmatic, ventromed sm stria medullaris thal SO supraoptic nu sox supraoptic decussation SPa subparaventric zone hy st stria terminalis Refer to Index of Abbreviations for other entries

Figure 67 P0 #26 3.63 mm

M1

M2

S1HL

S1Sh

RSD

S1DZ

cg

S1BF

RSGc CA2

fmj CA3

CA1 D3V

DG

sm

MHb

ne LDDM

LH

LDVL

fi st

MDL PC

VL

ic VPL

CM

DEn Rt

Rh Re

Sub mt

Pir

VRe A13 PaXi ZIR PaLM PaMP JPLH 3V Stg AHP f PLH PaV

SCh sox

GP

VM

Xi

Pe

GI DI AID AIV

RtSt

MDM IMD

S2 CPu

CL

PV

S1ULp

ne

SPa AHC

CeC EA CeM I BMA AA

EP

cst ACo

MeAD MeAV

VLH ESO SO

VEn TempM TempS TMJ CxA

LOT2 ZygA Cond

BAOT

TuLH opt

LPtg

BSph

ptgpal

5Gn/5n

cty

NasC Ptg

Mc MPtg

ialn

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5Gn/5n trigem ganglion and nerve AA anterior amyg area ACo ant cortical amygdaloid nu AHC anterior hy area, central AHP ant hypothal area, post AID agranular insular cx, dorsal AIV agranular insular cx, vent BAOT bed nu access olfactory tr BMA basomed amyg nu, ant BSph basisphenoid bone CeC central amyg nu, capsular CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu Cond condylar process mandible CPu caudate putamen cst comm stria terminalis cty chorda tympani nerve CxA cortex-amyg transition D3V dorsal 3rd ventricle DEn dorsal endopiriform nu DG dentate gyrus DI dysgranular insular cx EA sublenticular extend amyg EP entopeduncular nu ESO episupraoptic nu f fornix fi fimbria hippocampus fmj forceps maj corpus call GI granular insular cx GP globus pallidus I intercalated nuclei amyg ialn inferior alveolar nerve ic internal capsule IMD intermediodorsal thal nu JPLH juxtaparaventricular lat hy LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LH lateral hypothalamic area LOT2 nu lat olf tract, layer 2 LPtg lat pterygoid muscle M1 primary motor cx M2 secondary motor cx Mc Meckel’s cartilage MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent MHb med habenular nu MPtg medial pterygoid muscle mt mammillothalamic tract NasC nasal cavity ne neuroepithelium opt optic tract Oral oral cavity PaLM paravent hy, lat magnocell PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir piriform cortex PLH peduncular part lat hy Ptg pterygoid proces sphenoid ptgpal pterygopalatine n PV paraventricular thalamic nu Re reuniens thalamic nu Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1HL prim somatosens, hindlimb S1Sh prim somatosens, shoulder S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SCh suprachiasmatic nu sm stria medullaris thal SO supraoptic nu sox supraoptic decussation SPa subparaventric zone hy st stria terminalis Stg stigmoid hypothal nu Sub submedius thalamic nu TempM temporalis muscle TempS temporal bone, squamous TMJ temporomandibular joint TuLH tuberal region lat hy Refer to Index of Abbreviations for other entries

Figure 68 P0 #27 3.75mm

M1

M2

S1HL S1Tr

RSD

S1DZ

cg RSGc fmj CA2 CA3

CA1

D3V

LV

DG

sm

LDDM

LHb PV

LDVL fi

S2 CPu

CL MDL

st

eml

Po

IMD

VPM

CM Rh

Sub

GP

Rt

PC

Re Xi

S1ULp

ne

MHb

MDC

S1BF

alv

A13 ZIR

ZIV

f

EP

cst AA I PLH

PeFLH PTe PaMP SO Pe VMHSh SCh opt RChL sox RCh BSph

DEn 3 VEn

AL

AHP AHC

AIP

La CeL ASt CeM CeC

SPa PaPo

3V

VCl

B

mt

PaDC

GI DI rf

ic VM

PaXi

DCl

MeAD

TempS

BLA

BMA

MeAV

5Gn

2 Pir1

ACo ASph

BAOT

Cond masn

ptgpal

LPtg

cty

lgn Mc

NasC Ptg MPtg

ialn Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5Gn trigeminal ganglion AA anterior amyg area ACo ant cortical amygdaloid nu AHC anterior hy area, central AHP ant hypothal area, post AIP agranular insular cx, post AL nu ansa lenticularis alv alveus hippocampus ASph alisphenoid bone ASt amygdalostriatal transition B basal nu (Meynert) BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BMA basomed amyg nu, ant BSph basisphenoid bone CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) cst comm stria terminalis cty chorda tympani nerve D3V dorsal 3rd ventricle DCl dors part of claustrum DEn dorsal endopiriform nu DG dentate gyrus DI dysgranular insular cx eml external medullary lamina EP entopeduncular nu f fornix fi fimbria hippocampus fmj forceps maj corpus call GI granular insular cx GP globus pallidus I intercalated nuclei amyg ialn inferior alveolar nerve ic internal capsule IMD intermediodorsal thal nu La lat amygdaloid nu LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat lgn lingual nerve LHb lateral habenular nu LPtg lateral pterygoid muscle LV lateral ventricle M1 primary motor cx M2 secondary motor cx masn masseteric nerve Mc Meckel’s cartilage MDC MD thal nu, central MDL mediodorsal thalamic nu, lat MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent MHb med habenular nu MPtg medial pterygoid muscle mt mammillothalamic tract NasC nasal cavity ne neuroepithelium opt optic tract Oral oral cavity PaDC paraventric hy dorsal cap PaMP paravent hy, med parvicell PaPo paraventricular hy nu, post PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu PeFLH perifornical part of lat hy Pir1 piriform cx, layer 1 PLH peduncular part lat hy Po post thal nuclear group PTe paraterete nu Ptg pterygoid proces sphenoid ptgpal pterygopalatine n PV paraventricular thalamic nu RCh retrochiasmatic area RChL retrochiasmatic, lateral Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1HL prim somatosens, hindlimb S1Tr prim somatosens, trunk S1ULp prim somatosens, upper lip S2 2ary somatosensory cx Refer to Index of Abbreviations for other entries

Figure 69 P0 #28 3.87 mm

M1

M2

S1Tr

RSD

S1DZ

cg fmj

RSGc

dcw

RSGb

CA1

DS

D3V

CA2

DG

sm MHb

LPMR

LHb PVP IMD

MDM

MDL

OPC

VPM

A11

ic

ZID ZIV EP

CeM cst

PeFLH

STIA

MeAD

PLH

VMHDM

SO MeAV

VMHVL

opt RChL sox

BSph

3n

La

CeC BLA VEn BLV

3

2

Pir1 TempS TMJ

BMA

f

Arc

DEn

CeL

MCLH Pe DM

rf

GP

SubI

DA

3V

st Rt

A13

GI DI Cl AIP

CPu

VPL

VM

Sub mt

S2

fi

VG str

VPPC

PHD

ne

bsc IGL

Po

PC CM RRe

DLG

S1ULp

ec

CA3

LPLR

CL

fr

S1BF

ictd

ACo ASph

BAOT masn

Cond

LPtg

5Gn cty

ASph

NasC

Mc Ptg

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

ialn

MasM

MPtg

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 3V 3rd ventricle 5Gn trigeminal ganglion ACo ant cortical amygdaloid nu AIP agranular insular cx, post Arc arcuate hypothal nu ASph alisphenoid bone BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BLV basolat amyg, ventral BMA basomed amyg nu, ant bsc brachium superior colliculus BSph basisphenoid bone CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum CL centrolateral thal nu Cl claustrum CM central medial thal nu Cond condylar process mandible CPu caudate putamen (striatum) cst comm stria terminalis cty chorda tympani nerve D3V dorsal 3rd ventricle DA dorsal hypothal area dcw deep cerebral white DEn dorsal endopiriform nu DG dentate gyrus DI dysgranular insular cx DLG dorsal lat geniculate nu DM dorsomed hypothal nu DS dorsal subiculum ec external capsule EP entopeduncular nu f fornix fi fimbria hippocampus fmj forceps maj corpus call fr fasciculus retroflexus GI granular insular cx GP globus pallidus ialn inferior alveolar nerve ic internal capsule ictd internal carotid artery IGL intergeniculate leaf IMD intermediodorsal thal nu La lat amygdaloid nu LHb lateral habenular nu LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LPtg lat pterygoid muscle M1 primary motor cx M2 secondary motor cx MasM masseter muscle masn masseteric nerve Mc Meckel’s cartilage MCLH magnocell nu lat hypothal MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent MHb med habenular nu MPtg medial pterygoid muscle mt mammillothalamic tract NasC nasal cavity ne neuroepithelium OPC oval paracentral thal nu opt optic tract PC paracentral thal nu Pe periventricular hypothal nu PeFLH perifornical part of lat hy PHD post hypothal area, dorsal Pir1 piriform cx, layer 1 PLH peduncular lat hypothal Po post thal nuclear group Ptg pterygoid proces sphenoid PTg pedunculopontine teg nu PVP paraventricular thal nu, post RChL retrochiasmatic, lateral rf rhinal fissure RRe retrouniens area RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c Rt reticular thal nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1Tr prim somatosens, trunk S1ULp prim somatosens, upper lip S2 2ary somatosensory cx sm stria medullaris thal SO supraoptic nu Refer to Index of Abbreviations for other entries

Figure 70 P0 #29 3.99 mm

MPtA

LPtA

S1Tr S1DZ

RSD cg

S1BF

RSGc fmj RSGb

hbc

Hi

D3V

LPLR

sm

ec

LPMR

LHb fr fr OPC

CPu

VG

ZID

ml

SubG

CeM

ic

SubI

MePD STIA

PH

La

CeC

3 2 VEn

I

Pir1 TempS

BLA

PeFLH

VM HD VM M VM HC HV L

DEn

CeL STh

A13

PLH

PeF f TuLH

BLV

MeAD BMA

Te opt

5Gn/5n

PLCo ACo ASph masn

LPtg

4n ASph

TMJ

BMP

MeAV BAOT

MTu

Arc RCh

rf

ZIV

A11 mt

3V

PRh

st

PR

DM

Ect

ic

IGL

VPPC SPF

AuV fi

VPM VPL

PF

CM

bsc

DLG str

Po

PoMn

Au1

IMA

CL PVP

S2 AuD

ptgpal

cty Mc

mxa

MPtg

MasM

Man

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 4n trochlear nerve 5Gn/5n trigem ganglion and nerve ACo ant cortical amygdaloid nu Arc arcuate hypothal nu ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BLV basolat amyg, ventral BMA basomed amyg nu, ant BMP basomed amyg nu, post bsc brachium superior colliculus CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) cty chorda tympani nerve D3V dorsal 3rd ventricle DEn dorsal endopiriform nu DLG dorsal lat geniculate nu DM dorsomed hypothal nu ec external capsule Ect ectorhinal cortex f fornix fi fimbria hippocampus fmj forceps maj corpus call fr fasciculus retroflexus hbc habenular commissure Hi hippocampal region I intercalated nuclei amyg ic internal capsule IGL intergeniculate leaf IMA intramedullary thalamic area La lat amygdaloid nu LHb lateral habenular nu LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LPtA lat parietal association cx LPtg lat pterygoid muscle Man mandible MasM masseter muscle masn masseteric nerve Mc Meckel’s cartilage MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent MePD med amygd nu, posterodors ml medial lemniscus MPtA med parietal association cx MPtg medial pterygoid muscle mt mammillothalamic tract MTu medial tuberal nu mxa maxillary artery OPC oval paracentral thal nu opt optic tract PeF perifornical nu PeFLH perifornical part of lat hy PF parafascicular thal nu PH posterior hypothal nu Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy Po post thal nuclear group PoMn posteromedian thal nu PR prerubral field PRh perirhinal cx ptgpal pterygopalatine n PVP paraventricular thal nu, post RCh retrochiasmatic area rf rhinal fissure RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1Tr prim somatosens, trunk S2 2ary somatosensory cx sm stria medullaris thal SPF subparafascicular thal nu st stria terminalis STh subthalamic nu STIA ST, intraamygdaloid div str superior thalamic radiation SubG subgeniculate nu SubI subincertal nu Te terete hypothal nu TempS temporal bone, squamous Refer to Index of Abbreviations for other entries

Figure 71 P0 #30 4.11mm

V2MM

V2ML

V1

RSD

V2L Pt

RSGc fmj

dcw

RSGb hbc D3V

bsc

LHb

MHb

AuD

Hi

DS

RSGa

S1

LPMR

Au1

LPLR IMA DLG

PrC PV Po PF fr

CPu Ect

fi

ml

ZID

PR

A11 SPF

VG

VPM

VPPC

AuV

IGL

VPL

PRh

SubG

ZIV

La

CeC mt

PHD

PSTh

SMT

PH

STh

STIA ic

DM

MePV

VMHVL

MTu

ArcD

PLH opt

3n 6n

ASph

BSph Ptg

BLV

Pir

TMJ

BMP RAPir PLCo Cond

PMCo

ASph

ictd 5Gn/5n

ArcM ArcL

DEn

TempS

AHiAL

sox Te

BLP

BLA

MCLH PeF f TuLH

VMHDM

I

MePD

PeFLH DMC

rf

st

4n

LPtg

5man Oral ptgpal MPtg

Mc MasM

TPal

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 4n trochlear nerve 5Gn/5n trigem ganglion and nerve 5man 5n, mandibular division 6n root of abducens nerve AHiAL amygdalohip area, antlat ArcD arcuate hypothal nu, dors ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLA basolat amyg nu, ant BLP basolat amyg nu, post BLV basolat amyg, ventral BMP basomed amyg nu, post bsc brachium superior colliculus BSph basisphenoid bone CeC central amyg nu, capsular Cond condylar process mandible CPu caudate putamen (striatum) D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu DLG dorsal lat geniculate nu DM dorsomed hypothal nu DMC dorsomed hy nu, compact DS dorsal subiculum Ect ectorhinal cortex f fornix fi fimbria hippocampus fmj forceps maj corpus call fr fasciculus retroflexus hbc habenular commissure Hi hippocampal region I intercalated nuclei amyg ic internal capsule ictd internal carotid artery IGL intergeniculate leaf IMA intramedullary thalamic area La lat amygdaloid nu LHb lateral habenular nu LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LPtg lat pterygoid muscle MasM masseter muscle Mc Meckel’s cartilage MCLH magnocell nu lat hypothal MePD med amygd nu, posterodors MePV med amyg nu, posterovent MHb med habenular nu ml medial lemniscus MPtg medial pterygoid muscle mt mammillothalamic tract MTu medial tuberal nu opt optic tract Oral oral cavity PeF perifornical nu PeFLH perifornical part of lat hy PF parafascicular thal nu PH posterior hypothal nu PHD post hypothal area, dorsal Pir piriform cortex PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PR prerubral field PrC precommissural nu PRh perirhinal cx PSTh parasubthalamic nu Pt parietal cortex Ptg pterygoid proces sphenoid ptgpal pterygopalatine n PV paraventricular thalamic nu RAPir rostral amygdalopiriform rf rhinal fissure RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c S1 primary somatosensory cx SMT submammillothalamic nu sox supraoptic decussation SPF subparafascicular thal nu st stria terminalis STh subthalamic nu STIA ST, intraamygdaloid div SubG subgeniculate nu Te terete hypothal nu TempS temporal bone, squamous Refer to Index of Abbreviations for other entries

Figure 72 P0 #31 4.23 mm

V2MM

V2ML

RSD

V1

DS

RSGa

D3V

AuD

OPT

SCO

Pt

dcw

RSGb

hbc

V2L

fmj

RSGc

PrC

bsc APT

Au1

LP IMA Po

p1PAG

Hi DLG AuV

IGL PF

VPM VG

TeA

fr ZID

ml RI

PR

CPu Ect SubG

ZIR

F

fi st

PH mt

STh

Gem PSTh

BLP

PeFLH DMC DM

ArcM ArcL

PMCo

TempS TMJ

ASph

Cond

BMP

PLCo

ictd

Te

6n

BLV

RAPir

VMHDM

MTu

Pir1

AHiAL

PLH

PeF f

VMHVL

MePV

3 2

BLA

MePD MCLH

rf DEn

STIA

ic

PRh

La

Ce

I

PHA 3V

IMG

3n

LPtg

5Gn/5n

5man OvalW ptgpal cty Otic

Mc

masv

Gonial MPtg

NasC HPtg

MasM

TPal

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Man

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 3V 3rd ventricle 5Gn/5n trigem ganglion and nerve 5man 5n, mandibular division 6n root of abducens nerve AHiAL amygdalohip area, antlat APT anterior pretectal nu ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLA basolat amyg nu, ant BLP basolat amyg nu, post BLV basolat amyg, ventral BMP basomed amyg nu, post bsc brachium superior colliculus Ce central amygdaloid nu Cond condylar process mandible CPu caudate putamen (striatum) cty chorda tympani nerve D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu DLG dorsal lat geniculate nu DM dorsomed hypothal nu DMC dorsomed hy nu, compact DS dorsal subiculum Ect ectorhinal cortex F nu fields of Forel f fornix fi fimbria hippocampus fmj forceps maj corpus call fr fasciculus retroflexus Gem gemini hypothalamic nu Gonial gonial process hbc habenular commissure Hi hippocampal region HPtg hamulus pterygoid bone I intercalated nuclei amyg ic internal capsule ictd internal carotid artery IGL intergeniculate leaf IMA intramedullary thalamic area IMG amyg intramedullary gr La lat amygdaloid nu LP lateral posterior thal nu LPtg lat pterygoid muscle Man mandible MasM masseter muscle masv masseteric vein Mc Meckel’s cartilage MCLH magnocell nu lat hypothal MePD med amygd nu, posterodors MePV med amyg nu, posterovent ml medial lemniscus MPtg medial pterygoid muscle mt mammillothalamic tract MTu medial tuberal nu NasC nasal cavity OPT olivary pretectal nu Otic otic ganglion OvalW oval window p1PAG p1 periaqueductal gray PeF perifornical nu PeFLH perifornical part of lat hy PF parafascicular thal nu PH posterior hypothal nu PHA posterior hypothal area Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PR prerubral field PrC precommissural nu PRh perirhinal cx PSTh parasubthalamic nu Pt parietal cortex ptgpal pterygopalatine n RAPir rostral amygdalopiriform rf rhinal fissure RI rostral interstitial nu of mlf RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c SCO subcommissural organ st stria terminalis STh subthalamic nu STIA ST, intraamygdaloid div Refer to Index of Abbreviations for other entries

Figure 73 P0 #32 4.35 mm

V2MM

V2ML

RSD

V1

LV RSGc

V2L dcw

fmj

Pt

RSGb D3V

RSGa

pc MPT SCO

DS

AuD

OPT bsc

LP

MCPC

DLG

p1Rt

Lth RPF

AuV

Po

Sc

MGM

Eth

ml

A11

Au1

DG

APT PLi

TG PrC

Post

IGL

VPM

TeA VG

fr

CA3

ZID

PR F

Ect

ZIV

PRh

mtg STh ic

PH PSTh

mt

PHA

A14

PeF f

PeFLH VMHSh

VMH

ArcM

MePV

MCLH

DMV Pe DMD

MTu ArcL

BSph

LV st MePD

SMT PMD

La DEn

fi

FF

ictd 6n

3n 5Gn

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Cond LPtg

4n

ASph

NasC

TMJ

RAPir PLCo

5man

Otic

MPtg

Pir1 TempS

BMP

PMCo

Te

3 2

BLP

STIA AHiAL

PLH

rf

ptgpal Mc Gonial mxv

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 4n trochlear nerve 5Gn trigeminal ganglion 5man 5n, mandibular division 6n root of abducens nerve AHiAL amygdalohip area, antlat APT anterior pretectal nu ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post BMP basomed amyg nu, post bsc brachium superior colliculus BSph basisphenoid bone Cond condylar process mandible D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu DG dentate gyrus DLG dorsal lat geniculate nu DMD dorsomed hypothal nu,dorsal DMV dorsomed hy nu, ventral DS dorsal subiculum Ect ectorhinal cortex Eth ethmoid thalamic nu F nu fields of Forel f fornix FF fields of Forel fi fimbria hippocampus fmj forceps maj corpus call fr fasciculus retroflexus Gonial gonial process ic internal capsule ictd internal carotid artery IGL intergeniculate leaf La lat amygdaloid nu LP lateral posterior thal nu LPtg lat pterygoid muscle Lth lithoid nu LV lateral ventricle Mc Meckel’s cartilage MCLH magnocell nu lat hypothal MCPC magnocell nu post comm MePD med amygd nu, posterodors MePV med amyg nu, posterovent MGM med geniculate nu, medial ml medial lemniscus MPT medial pretectal nu MPtg medial pterygoid muscle mt mammillothalamic tract mtg mammillotegmental tract MTu medial tuberal nu mxv maxillary vein NasC nasal cavity OPT olivary pretectal nu Otic otic ganglion p1Rt p1 reticular formation pc posterior comm Pe periventricular hypothal nu PeF perifornical nu PeFLH perifornical part of lat hy PH posterior hypothal nu PHA posterior hypothal area Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PLi posterior limitans thal nu PMCo posteromed cortical amyg nu PMD premammillary nu, dors Po post thal nuclear group Post postsubiculum PR prerubral field PrC precommissural nu PRh perirhinal cx PSTh parasubthalamic nu Pt parietal cortex ptgpal pterygopalatine n RAPir rostral amygdalopiriform rf rhinal fissure RPF retroparafascicular nu RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c Sc scaphoid thal nu SCO subcommissural organ SMT submammillothalamic nu st stria terminalis STh subthalamic nu Refer to Index of Abbreviations for other entries

Figure 74 P0 #33 4.47 mm

V2MM

V2ML

RSD

V1

RSGc fmj RSGb

V2L Pt

RSGa

D3V

Post

DS

csc MPT OTOPT pc PaC InWh SCO

bsc

p1PAG

APT

TG

Eth REth ml

PR

SuML

ZIV LT

LV

STh

BLP AHiPL BMP AHiPM

ML

MM

PRh La

ic PSTh

PMD

PLH

DTM PMV

Ect

CA3

EpP

SNR

SNCD

mt

MnM

TeA

opt

PBP

PHA

SuMM

VG

PIL ZIC

VTAR

AuV

Po

p1Rt

fr mtg

sumx

MG

MCPC

Dk InC

Au1

DG

LP

PLi

Lth

AuD

DEn 3

ArcD

2

rf

Pir1

APir

PMCo

f

PLCo

DM 3V

DLEnt

Cond ictd

VMH MTu

ArcM

5Gn ptgpal

ArcL ASph

MEI MEE BSph NasC

TPal

Gonial

Mc masn ExOrb

MPtg

HPtg

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle 5Gn trigeminal ganglion AHiPL amygdalohip area, postlat AHiPM amygdalohip, posteromed APir amygdalopiriform transition APT anterior pretectal nu ArcD arcuate hypothal nu, dors ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post BMP basomed amyg nu, post bsc brachium superior colliculus BSph basisphenoid bone Cond condylar process mandible csc comm superior colliculus D3V dorsal 3rd ventricle DEn dorsal endopiriform nu DG dentate gyrus Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DM dorsomed hypothal nu DS dorsal subiculum DTM dors tuberomammillary nu Ect ectorhinal cortex EpP epipeduncular nu Eth ethmoid thalamic nu ExOrb exorbital gland f fornix fmj forceps maj corpus call fr fasciculus retroflexus Gonial gonial process HPtg hamulus pterygoid bone ic internal capsule ictd internal carotid artery InC interstitial nu of Cajal InWh intermediate white layer SC La lat amygdaloid nu LP lateral posterior thal nu LT lat terminal nu acc optic tr Lth lithoid nu LV lateral ventricle masn masseteric nerve Mc Meckel’s cartilage MCPC magnocell nu post comm MEE medial eminence, ext layer MEI medial eminence, internal layer MG med geniculate nu ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MnM medial mammillary nu, med MPT medial pretectal nu MPtg medial pterygoid muscle mt mammillothalamic tract mtg mammillotegmental tract MTu medial tuberal nu NasC nasal cavity OPT olivary pretectal nu opt optic tract OT nu of the optic tract p1PAG p1 periaqueductal gray p1Rt p1 reticular formation PaC paracomm nu post com PBP parabrachial pigmented nu pc posterior comm PHA posterior hypothal area PIL post intralaminar thal nu Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PLi posterior limitans thal nu PMCo posteromed cortical amyg nu PMD premammillary nu, dors PMV premammillary nu, vent Po post thal nuclear group Post postsubiculum PR prerubral field PRh perirhinal cx PSTh parasubthalamic nu Pt parietal cortex ptgpal pterygopalatine n REth retroethmoid nu rf rhinal fissure RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c SCO subcommissural organ Refer to Index of Abbreviations for other entries

Figure 75 P0 #34 4.59 mm

RSD

sss

V2MM V2ML

RSGc

dcw

Pi

RSGb

RSGa V2L

Post

PPT SC

bsc

OPT

csc

OT

csc ne

V1

PCom

APT Po

PLi

p1Rt

PoT

Dk

MGV DG MGM

Au1

CA1

AuV

PIL

InC

ZIC

R

mtg

AuD

MGD

SG

Lth

Pt

PrS LP

TG

MCPC

DS

VTAR

TeA

SNCD

ml

fr

opt PP LT

PBP

Ect

SNR

PRh

ic SuMM

CA3

SuML MnM ML

f

VS

VTM

NasC

5Gn 3n

ictd 6n

MEE

AHiPM trs

PMCo

LH

ArcLP MEI

DLEnt rf

PLCo

DTM PMD 3V PMV DM ArcMP

La

BLP 3 DEn 2 AHiPL Pir1 APir

PSTh

MM

LV

ptgpal

Mc

m5

ASph

Gonial

TPal HPtg

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 3V 3rd ventricle 5Gn trigeminal ganglion 6n root of abducens nerve AHiPL amygdalohip area, postlat AHiPM amygdalohip, posteromed APir amygdalopiriform transition APT anterior pretectal nu ArcLP arcuate hy nu, lateropost ArcMP arcuate hy nu, med post ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post bsc brachium superior colliculus csc comm superior colliculus dcw deep cerebral white DEn dorsal endopiriform nu DG dentate gyrus Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DM dorsomed hypothal nu DS dorsal subiculum DTM dors tuberomammillary nu Ect ectorhinal cortex f fornix fr fasciculus retroflexus Gonial gonial process HPtg hamulus pterygoid bone ic internal capsule ictd internal carotid artery InC interstitial nu of Cajal La lat amygdaloid nu LH lateral hypothalamic area LP lateral posterior thal nu LT lat terminal nu acc optic tr Lth lithoid nu LV lateral ventricle m5 motor root trigeminal nerve Mc Meckel’s cartilage MCPC magnocell nu post comm MEE medial eminence, ext layer MEI medial eminence, internal layer MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MnM medial mammillary nu, med mtg mammillotegmental tract NasC nasal cavity ne neuroepithelium OPT olivary pretectal nu opt optic tract OT nu of the optic tract p1Rt p1 reticular formation PBP parabrachial pigmented nu PCom nu posterior comm Pi pineal gland PIL post intralaminar thal nu Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLi posterior limitans thal nu PMCo posteromed cortical amyg nu PMD premammillary nu, dors PMV premammillary nu, vent Po post thal nuclear group Post postsubiculum PoT posterior thal nu, triangular PP peripeduncular nu PPT posterior pretectal nu PRh perirhinal cx PrS presubiculum PSTh parasubthalamic nu Pt parietal cortex ptgpal pterygopalatine n R red nu rf rhinal fissure RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c SC superior colliculus SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNR s nigra, reticular sss superior sagittal sinus SuML supramammillary nu, lat SuMM supramammillary nu, medial TeA temporal associatin cx Refer to Index of Abbreviations for other entries

Figure 76 P0 #35 4.71 mm

sss

V2MM

RSD

V2ML

RSGc Pi

V1

RSGb

RSGa

csc PCom

OT

Au1 MGD

APT Po

DG

PIL

R ml

IPF SuMM

fr VTAR PBP

SNL LT SNCD

Ect

CA3 hif

SNR SNCM

ic

PRh

LV DLEnt

SuML PSTh

MM ML ne PMD 3V PMV

VS

DG

AHiPM

f

APir

LM VTM PLH 3n

ArcMP

pcer 4n

MEI APit

trs

PMCo

s5 m5

MEE

TeA

SubB

mtg

IF

AuV

PoT

scp RLi

MGV MGM

InC

PrEW

SG

PLi

p1Rt

AuD

DS

PrS

TG PPT

InWh

Aq Dk

V2L

Zo

InG

ne

ne

Post

SuG Op

5Gn

ptgpal

Mc

ictd 6n

ASph

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5Gn trigeminal ganglion 6n root of abducens nerve AHiPM amygdalohip, posteromed APir amygdalopiriform transition APit anterior lobe pituitary APT anterior pretectal nu Aq aqueduct ArcMP arcuate hy nu, med post ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral csc comm superior colliculus DG dentate gyrus Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DS dorsal subiculum Ect ectorhinal cortex f fornix fr fasciculus retroflexus hif hippocampal fissure ic internal capsule ictd internal carotid artery IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPF interpedunc fossa LM lateral mammillary nu LT lat terminal nu acc optic tr LV lateral ventricle m5 motor root trigeminal nerve Mc Meckel’s cartilage MEE medial eminence, ext layer MEI medial eminence, internal layer MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial mtg mammillotegmental tract ne neuroepithelium Op optic nerve layer sup coll OT nu of the optic tract p1Rt p1 reticular formation PBP parabrachial pigmented nu pcer post cerebral art PCom nu posterior comm Pi pineal gland PIL post intralaminar thal nu PLH peduncular part lat hy PLi posterior limitans thal nu PMCo posteromed cortical amyg nu PMD premammillary nu, dors PMV premammillary nu, vent Po post thal nuclear group Post postsubiculum PoT posterior thal nu, triangular PPT posterior pretectal nu PrEW pre-Edinger-Westphal nu PRh perirhinal cx PrS presubiculum PSTh parasubthalamic nu ptgpal pterygopalatine n R red nu RLi rostral linear nu raphe RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c s5 sensory root trigem n scp superior Cb peduncle SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNCM s nigra, compact, med tier SNL s nigra, lateral SNR s nigra, reticular sss superior sagittal sinus SubB subbrachial nu SuG superficial gray sup coll SuML supramammillary nu, lat SuMM supramammillary nu, medial TeA temporal associatin cx TG tectal gray trs transverse sinus V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat Refer to Index of Abbreviations for other entries

Figure 77 P0 #36 4.83 mm

RSD

sss

V2MM

V2ML

RSGc Pi

RSGb Zo SuG Op InG

DMPAG

V1 RSGa V2L

InWh

PlPAG

LPAG

PrEW

PrS

IF

TeA

DG SubB

RMC SNCD

AuV

MGV MGM

PoT PIL

RPC

PBP

IPR fr

SG

Po

APT

MA3 scp RLi

Au1

MGD

DLPAG

Dk InC

AuD

DS

DpG Aq

Pt

Post

hif

SNL

S

Ect

ml

PRh

SNCV

PIF SNCD

IPF MT

DLEnt

ic DG

3n

lfp tfp

VS

LM

Pn

rf

CA3

SNR

AHiPM

trs

APir

pcer

bas

PMCo

4n

Mall

3n

PPit IPit

APit ictd

Ctd ASph cpx

ptgpal

5Gn

m5

ptgcn

TT

Inc

EAM

BSph

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 4n trochlear nerve 5Gn trigeminal ganglion AHiPM amygdalohip, posteromed APir amygdalopiriform transition APit anterior lobe pituitary APT anterior pretectal nu Aq aqueduct ASph alisphenoid bone Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral bas basilar artery BSph basisphenoid bone cpx carotid plexus Ctd carotid canal DG dentate gyrus Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DS dorsal subiculum EAM sublent extended amyg, med Ect ectorhinal cortex fr fasciculus retroflexus hif hippocampal fissure ic internal capsule ictd internal carotid artery IF interfascicular nu InC interstitial nu of Cajal Inc incus InG intermed gray layer SC InWh intermediate white layer SC IPF interpedunc fossa IPit intermediate lobe pit IPR interpedunc nu, rostral sub lfp longitudinal fasciculus pons LM lateral mammillary nu LPAG lat periaqueductal gray m5 motor root trigeminal nerve MA3 med access oculomotor nu Mall malleus MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral ml medial lemniscus MT med terminal nu acc optic tr Op optic nerve layer sup coll PBP parabrachial pigmented nu pcer post cerebral art Pi pineal gland PIF parainterfascicular nu VTA PIL post intralaminar thal nu PlPAG pleoglial PAG PMCo posteromed cortical amyg Pn pontine nuclei Po post thal nuclear group Post postsubiculum PoT posterior thal nu, triangular PPit posterior lobe pit PrEW pre-Edinger-Westphal nu PRh perirhinal cx PrS presubiculum Pt parietal cortex ptgcn nerve of the pterygoid canal ptgpal pterygopalatine n rf rhinal fissure RLi rostral linear nu RMC red nu, magnocell part RPC red nu, parvicell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c S subiculum scp superior Cb peduncle SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNCV s nigra, compact, vent tier SNL s nigra, lateral SNR s nigra, reticular sss superior sagittal sinus SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx tfp transverse fibers pons trs transverse sinus TT tensor tympani muscle V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat Refer to Index of Abbreviations for other entries

Figure 78 P0 #37 4.95 mm

V2MM V2ML RSD RSGc

sss

RSGb

Zo SuG

V1

RSGa

Op

V2L

InG csc DpWh DMPAG PlPAG DLPAG

Aq

Post AuD

InWh

Au1

DpG

LPAG

mRt

Dk

MA3 PrEW

InC

SG

PoT PaR

PIL

RPC

AuV

MGV MGM

TeA S

SubB

RMC

RLi mlf

PrS

MGD

SNCD

IF IPR IPDL

PIF

rf

DG ic

IPF

DLEnt

4n VLL

Pn

Pn

APir

AHiPM

tfp tfp

PRh

SNCM

IPL IPC IPI

LV

SNR

PBP

Ect

trs

PMCo

mcp

ParP

s5

m5

5Gn

bas

ptgpal

Mall

IPit PPit APit BSph

TempP

6n

TT

Ctd

ictd

Apex EAM

cpx

NasC

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

ExOrb

0

0.2

0.4

0.6

0.8

1.0 mm

4n trochlear nerve 5Gn trigeminal ganglion 6n root of abducens nerve AHiPM amygdalohip, posteromed Apex apex of cochlea APir amygdalopiriform trans APit anterior lobe pituitary Aq aqueduct Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral bas basilar artery BSph basisphenoid bone cpx carotid plexus csc comm superior colliculus Ctd carotid canal DG dentate gyrus Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll EAM sublent extended amyg, med Ect ectorhinal cortex ExOrb exorbital gland ic internal capsule ictd internal carotid artery IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPC IPC nu, caudal IPDL interpedunc nu, dorsolat IPF interpedunc fossa IPI interpedunc nu, intermed IPit intermediate lobe pit IPL interpedunc nu, lat subnu IPR interpedunc nu, rostral sub LPAG lat periaqueductal gray LV lateral ventricle m5 motor root trigeminal nerve MA3 med access oculomotor nu Mall malleus mcp middle cerebellar peduncle MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral mlf med longitudinal fasciculus mRt mesenceph reticular form NasC nasal cavity Op optic nerve layer sup coll Oral oral cavity PaR pararubral nu ParP parietal plate PBP parabrachial pigmented nu PIF parainterfascicular nu VTA PIL post intralaminar thal nu PlPAG pleoglial PAG PMCo posteromed cortical amyg nu Pn pontine nuclei Post postsubiculum PoT posterior thal nu, triangular PPit posterior lobe pit PrEW pre-Edinger-Westphal nu PRh perirhinal cx PrS presubiculum ptgpal pterygopalatine n rf rhinal fissure RLi rostral linear nu raphe RMC red nu, magnocell part RPC red nu, parvicell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c S subiculum s5 sensory root trigem n SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNCM s nigra, compact, med tier SNR s nigra, reticular sss superior sagittal sinus SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx TempP temporal bone, petrous tfp transverse fibers pons trs transverse sinus TT tensor tympani muscle V1 primary visual cortex V2L 2ary visual cx, lat area Refer to Index of Abbreviations for other entries

Figure 79 P0 #38 5.07 mm

V2MM

RSD sss

V2ML

Zo

RSGb

Op

V1 RSGa

SuG

V2L

InG InWh

MA3

Au1

mRt

InC

mlf

PaR

RMC

IF PN

ne TeA

SNR

S Ect

SNCV cp

PIF IPDL

PrS

SNL

PBP

IPA IPR

SubB

dcw AuV

SNCD

SNCM

RLi

bic

BIC

Dk

EW

AuD

Post

DpG DMPAG DLPAG ne LPAG DpWh Aq A11

ml

PRh

DG

IPI

IPC

DLEnt ll ILL

PnO MnR

APir ParP

RtTg

trs

AHiPM

VLL

PMCo

lfp s5 mcp

Pn

tfp

m5

5Gn

Mall

ptgpal

bas IPit

6n

TempP

TyC

TT

CGn

APit

EAM

BSph cpx

ictd

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5Gn trigeminal ganglion 6n root of abducens nerve AHiPM amygdalohip, posteromed APir amygdalopiriform transition APit anterior lobe pituitary Aq aqueduct Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BSph basisphenoid bone CGn cochlear (spiral) ganglion cp cerebral peduncle cpx carotid plexus dcw deep cerebral white DG dentate gyrus Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll EAM sublent extended amyg, med Ect ectorhinal cortex EW Edinger-Westphal nu ictd internal carotid artery IF interfascicular nu ILL intermed nu lat lemniscus InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPA interpedunc nu, apical subnu IPC IPC nu, caudal IPDL interpedunc nu, dorsolat IPI interpedunc nu, intermed IPit intermediate lobe pit IPR interpedunc nu, rostral sub lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve MA3 med access oculomotor nu Mall malleus mcp middle cerebellar peduncle ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu mRt mesenceph reticular form ne neuroepithelium Op optic nerve layer sup coll PaR pararubral nu ParP parietal plate PBP parabrachial pigmented nu PIF parainterfascicular nu VTA PMCo posteromed cortical amyg nu PN paranigral nu of the VTA Pn pontine nuclei PnO pontine reticular nu, oral Post postsubiculum PRh perirhinal cx PrS presubiculum ptgpal pterygopalatine n RLi rostral linear nu raphe RMC red nu, magnocell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RtTg reticulotegmental nu pons S subiculum s5 sensory root trigem n SNCD s nigra, compact, dors tier SNCM s nigra, compact, med tier SNCV s nigra, compact, vent tier SNL s nigra, lateral SNR s nigra, reticular sss superior sagittal sinus SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx TempP temporal bone, petrous tfp transverse fibers pons trs transverse sinus TT tensor tympani muscle TyC tympanic cavity V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VLL ventral nu lat lemniscus Zo zona layer sup coll

Figure 80 P0 #39 5.19mm

V2MM

Zo Op

SuG

RSGb InG

RSGa

InWh

DpWh

DpG

RLi vtgx IF IPA IPC

bic

BIC ECIC

Su3C Su3 3PC InC 3N

mlf

V1 Post

DMPAG DLPAG ne Aq LPAG

EW

V2ML

RSD

mRt

PaR

V2L

PrS SubB

SNCD LV

RMC SNR

RRF

TeA

S

PBP Ect

cp

PRh

IPDL IPI PnO ILL

PMnR

DLEnt

DG

MPL

APir

AHiPM

trs

MnR

ParP

PMCo VLL

RtTg lfp tfp

mcp 5m

ll

5s 7n

Mall

7Gn ptgpal

Pn CD

bas

TT

6n ScTy

APit CGn

EAM HMall

BSph ictd Oral

cpx

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular 6n root of abducens nerve 7Gn facial nerve ganglion 7n facial nerve AHiPM amygdalohip, posteromed APir amygdalopiriform transition APit anterior lobe pituitary Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BSph basisphenoid bone CD cochlear duct CGn cochlear (spiral) ganglion cp cerebral peduncle cpx carotid plexus DG dentate gyrus DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll EAM sublent extended amyg, med ECIC external cx inferior coll Ect ectorhinal cortex EW Edinger-Westphal nu HMall handle of malleus ictd internal carotid artery IF interfascicular nu ILL intermed nu lat lemniscus InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPA interpedunc nu, apical subnu IPC IPC nu, caudal IPDL interpedunc nu, dorsolat IPI interpedunc nu, intermed lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray LV lateral ventricle m5 motor root trigeminal n Mall malleus mcp middle cerebellar peduncle mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu mRt mesenceph reticular form ne neuroepithelium Op optic nerve layer sup coll Oral oral cavity PaR pararubral nu ParP parietal plate PBP parabrachial pigmented nu PMCo posteromed cortical amyg nu PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Post postsubiculum PRh perirhinal cx PrS presubiculum ptgpal pterygopalatine n RLi rostral linear nu raphe RMC red nu, magnocell part RRF retrorubral field RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RtTg reticulotegmental nu pons S subiculum s5 sensory root trigeminal n ScTy scala tympani SNCD s nigra, compact, dors tier SNR s nigra, reticular Su3 supraoculomotor PAG Su3C supraoculomotor cap SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx tfp transverse fibers pons trs transverse sinus TT tensor tympani muscle V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VLL ventral nu lat lemniscus vtgx vent tegmental decussation Zo zona layer sup coll

Figure 81 P0 #40 5.31 mm

V2MM

SuG

Zo

V2ML

Op

RSD

InG

V1 RSGa

InWh DMPAG

DpG

DLPAG LPAG

Aq

DpWh

VLPAG DRD Su3C 3PC Su3 InC 3N PaR DRV RMC mlf RRF CLi PTg xscp

Post bic

ECIC BIC

V2L dcw

SubB

PrCnF

PrS

MiTg

TeA

cp

PaS

RR

Ect

IPA PMnR

MPL

PRh

ILL

DLEnt

PnO

CEnt

VLL

MnR

MPL ll

RtTg

trs

DIEnt VIEnt

m5

MEnt ParP

mcp VLL s5 Pn tfp

ml lfp

m5

Inc

7n

MVPO

ptgpal

Mall

TempP ScVe

bas

CGn

CD

TT

ScTy EAM CD CGn

BOcc

HMall ictd Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular 7n facial nerve Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BOcc basioccipital bone CD cochlear duct CEnt caudomed entothinal cx CGn cochlear (spiral) ganglion CLi caudal linear nu raphe cp cerebral peduncle dcw deep cerebral white DIEnt dorsintermed entorhinal cx DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral EAM sublent extended amyg, med ECIC external cx inferior coll Ect ectorhinal cortex HMall handle of malleus ictd internal carotid artery ILL intermed nu lat lemniscus InC interstitial nu of Cajal Inc incus InG intermed gray layer SC InWh intermediate white layer SC IPA interpedunc nu, apical subnu lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve Mall malleus mcp middle cerebellar peduncle MEnt med entorhinal cx MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu Op optic nerve layer sup coll Oral oral cavity PaR pararubral nu ParP parietal plate PaS parasubiculum PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Post postsubiculum PrCnF precuneiform area PRh perirhinal cx PrS presubiculum PTg pedunculopontine tegmental ptgpal pterygopalatine n RMC red nu, magnocell part RR retrorubral nu RRF retrorubral field RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RtTg reticulotegmental nu pons s5 sensory root trigem n ScTy scala tympani ScVe scala vestibuli Su3 supraoculomotor PAG Su3C supraoculomotor cap SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx TempP temporal bone, petrous tfp transverse fibers pons trs transverse sinus TT tensor tympani muscle V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VIEnt ventral intermed entorhinal VLL ventral nu lat lemniscus VLPAG ventlat periaqueductal gray xscp decussation sup cereb ped Zo zona layer sup coll

Figure 82 P0 #41 5.43 mm

V2MM V2ML Op V1

InG

RSD

InWh

bic

DpG DLPAG

DMPAG Aq

DRD VLPAG Su3C Su3 3N 3PC

PrCnF

SubB

PaS

dcw

TeA

PBG

MiTg RRF

mlf

PTg

Ect

RR cp

xscp

CLi

V2L

4n

DpWh

LPAG

DRV

RSGa BIC ECIC

PRh

CEnt

rf

DLL

LEnt

PMnR MnR

ILL

PnO

MEnt

MPL mcp RtTg ll

s5

7n

TempP

CAT ScVe

Tz py

ptgpal

7Gn 7n

m5

VLL

PnC

RIP

5TT

TT MVPO

bas

CD

CD

ScTy CGn BOcc

ScTy

LgCa

EAM

ictd TyBu

Oral

SCM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular 4n trochlear nerve 5TT motor trigem, tensor tymp 7Gn facial nerve ganglion 7n facial nerve Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BOcc basioccipital bone CAT nu central acoustic tr CD cochlear duct CEnt caudomed entothinal cx CGn cochlear (spiral) ganglion CLi caudal linear nu raphe cp cerebral peduncle dcw deep cerebral white DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral EAM sublent extended amyg, med ECIC external cx inferior coll Ect ectorhinal cortex ictd internal carotid artery ILL intermed nu lat lemniscus InG intermed gray layer SC InWh intermediate white layer SC LEnt lateral entorhinal cx LgCa longus capitis muscle ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MEnt med entorhinal cx MiTg microcell tegmental nu mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu Op optic nerve layer sup coll Oral oral cavity PaS parasubiculum PBG parabigeminal nu PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral PrCnF precuneiform area PRh perirhinal cx PTg pedunculopontine tegmental ptgpal pterygopalatine n py pyramidal tr rf rhinal fissure RIP raphe interpositus nu RR retrorubral nu RRF retrorubral field RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RtTg reticulotegmental nu pons s5 sensory root trigem n SCM superior constrictor ScTy scala tympani ScVe scala vestibuli Su3 supraoculomotor PAG Su3C supraoculomotor cap SubB subbrachial nu TeA temporal associatin cx TempP temporal bone, petrous TT tensor tympani muscle TyBu tympanic bulla Tz nu trapezoid body V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VLL ventral nu lat lemniscus VLPAG ventlat periaqueductal gray xscp decussation sup cereb ped

Figure 83 P0 #42 5.55 mm

Op InG InWh DpG DLPAG

DMPAG

BIC ECIC

DpWh bic

LPAG

Aq

Cx CnF

VLPAG DR

PBG

MiTg

4N DRI

mlf

CLi

xscp

PTg SPTg

ATg ts

MnR

MPL DLL

PMnR

PnO

ll

mcp

DMTg A7

5TT

Pr5

RtTg

s5

8vn

7n

VLL rs

PnC

VeGn

7n ptgpal

RIP

CAT Tz py

ScVe MVPO

bas

HMall CD ScTy

BOcc

CGn

10Gn

ScTy EAM CD

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4N trochlear nu 5TT motor trigem, tensor tymp 7n facial nerve 8vn vestibular root of 8th nerve 10Gn vagus nerve ganglion A7 A7 noradrenaline cells Aq aqueduct ATg anterior tegmental nu bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BOcc basioccipital bone CAT nu central acoustic tr CD cochlear duct CGn cochlear (spiral) ganglion CLi caudal linear nu raphe CnF cuneiform nu Cx cerebral cortex DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DpWh deep white superior coll DR dorsal raphe nu DRI dorsal raphe, interfascicular EAM sublent extended amyg, med ECIC external cx inferior coll HMall handle of malleus InG intermed gray layer SC InWh intermediate white layer SC ll lateral lemniscus LPAG lat periaqueductal gray mcp middle cerebellar peduncle MiTg microcell tegmental nu mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu Op optic nerve layer sup coll Oral oral cavity PBG parabigeminal nu PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PTg pedunculopontine tegmental ptgpal pterygopalatine n py pyramidal tr RIP raphe interpositus nu rs rubrospinal tract RtTg reticulotegmental nu pons s5 sensory root trigem n ScTy scala tympani ScVe scala vestibuli SPTg subpeduncular tegmental nu ts tectospinal tr Tz nu trapezoid body VeGn vestibular n ganglion VLL ventral nu lat lemniscus VLPAG ventlat periaqueductal gray xscp decussation sup cereb ped

Figure 84 P0 #43 5.67mm

Cx

Op InG InWh DpG DpWh

BIC ECIC

DLPAG

DMPAG

LPAG

Aq

PrCnF CnF

VLPAG DR

PBG

MiTg

4N

Cx

Pa4

DRI mlf

PTg

scp

Rbd

bic

ATg

SPTg

DLL MPL

PMnR ts PnO MnR

KF vsc cp P5

DMTg

A7

5N Pr5

RtTgL

sp5

5TT

VeGn PnC

7n LVPO

RIP

TempP

CAT MVPO Tz

py

7n

OvalW

Stap

ptgpal

CGn Mall

CD ScVe

BOcc Oral

Utr Vest

8cn

ScTy

bas

8vn

TyBu

EAM

10Gn

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4N trochlear nu 5N motor trigeminal nu 5TT motor trigem, tensor tymp 7n facial nerve 8cn cochlear root 8th nerve 8vn vestibular root of 8th nerve 10Gn vagus nerve ganglion A7 A7 noradrenaline cells Aq aqueduct ATg anterior tegmental nu bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BOcc basioccipital bone CAT nu central acoustic tr CD cochlear duct CGn cochlear (spiral) ganglion CnF cuneiform nu cp cerebral peduncle Cx cerebral cortex DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DpWh deep white superior coll DR dorsal raphe nu DRI dorsal raphe, interfascicular EAM sublent extended amyg, med ECIC external cx inferior coll InG intermed gray layer SC InWh intermediate white layer SC KF Kˆlliker-Fuse nu LPAG lat periaqueductal gray LVPO lateroventral periolivary nu Mall malleus MiTg microcell tegmental nu mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu Op optic nerve layer sup coll Oral oral cavity OvalW oval window P5 peritrigeminal zone Pa4 paratrochlear nu PBG parabigeminal nu PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PrCnF precuneiform area PTg pedunculopontine tegmental ptgpal pterygopalatine n py pyramidal tr Rbd rhabdoid nu RIP raphe interpositus nu RtTgL reticulotegmental pons, lat scp superior Cb peduncle ScTy scala tympani ScVe scala vestibuli sp5 spinal trigem tract SPTg subpeduncular tegmental nu Stap stapedius bone TempP temporal bone, petrous ts tectospinal tr TyBu tympanic bulla Tz nu trapezoid body Utr utricle VeGn vestibular n ganglion Vest vestibule of the inner ear VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr

Figure 85 P0 #44 5.79 mm

Op InG InWh DpG

BIC

DpWh DMPAG

bic

ParP

ECIC

DLPAG PrCnF LPAG

Aq

ne VLPAG DRL

DRD DRV

Cx

PBG

MiTg

CnF

trs

PDR Pa4 mlf DRI

PTg DLL MPL

PnO

PMnR MnR

KF

Su5

SubCD

mcp

ASCC VeGn

P5 5N

DMTg

HSCCA

sp5

ne

5TT

Pr5 8vn

SubCV A5

RIP PnV

PnC

RMg

ml Tz RPa py

7n rs

SPO

LSO

7n

Vest 8vn

LVPO 8cn

MVPO ScTy

Stap ptgpal

CGn

bas ScVe

EAM Mall

CD

BOcc 10Gn ictd

TyBu

Oral

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5N motor trigeminal nu 5TT motor trigem, tensor tymp 7n facial nerve 8cn cochlear root 8th nerve 8vn vestibular root of 8th nerve 10Gn vagus nerve ganglion A5 A5 noradrenaline cells Aq aqueduct ASCC anterior semicirc canal bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus BOcc basioccipital bone CD cochlear duct CGn cochlear (spiral) ganglion CnF cuneiform nu Cx cerebral cortex DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRI dorsal raphe, interfascicular DRL dorsal raphe nu, lateral DRV dorsal raphe nu, ventral EAM sublent extended amyg, med ECIC external cx inferior coll HSCCA horizontal SCC ictd internal carotid artery InG intermed gray layer SC InWh intermediate white layer SC KF Kˆlliker-Fuse nu LPAG lat periaqueductal gray LSO lat superior olive LVPO lateroventral periolivary nu Mall malleus mcp middle cerebellar peduncle MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu ne neuroepithelium Op optic nerve layer sup coll Oral oral cavity P5 peritrigeminal zone Pa4 paratrochlear nu ParP parietal plate PBG parabigeminal nu PDR posterodors raphe nu PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral PnV pontine retic nu, ventral Pr5 principal sensory trigem nu PrCnF precuneiform area PTg pedunculopontine tegmental ptgpal pterygopalatine n py pyramidal tr RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract ScTy scala tympani ScVe scala vestibuli sp5 spinal trigem tract SPO superior paraolivary nu Stap stapedius bone Su5 supratrigeminal nu SubCD subcoeruleus nu, dorsal SubCV subcoeruleus nu, ventral trs transverse sinus TyBu tympanic bulla Tz nu trapezoid body VeGn vestibular n ganglion Vest vestibule of the inner ear VLPAG ventlat periaqueductal gray

Figure 86 P0 #45 5.91 mm

Fro/Par Op InG InWh DpG DpWh DMPAG

DLPAG

Aq

ne

DRD DRV

LPAG

LDTg LDTg

DRI

Sag

CnF

MiTg

VLPAG

DRL PDR

ECIC

mlf

PBG ParP

LPB

ll

PTg

trs DLL

MPB

vsc

VTg PnO

PnR

Su5

mcp

KF

A7 DMTg

Cb 5N P5

ne mlf

PrS sp5 PnC

RIP PnR RMg ml RPa py

VCA HSCCA

7n rs

MSO

Stap

LSO SPO

LVPO

7n

Vest

IAud VeGn

StapM ScVe

MVPO

8cn

bas

ScTy

BOcc

CGn

CD 10Gn

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5N motor trigeminal nu 7n facial nerve 8cn cochlear root 8th nerve 10Gn vagus nerve ganglion A7 A7 noradrenaline cells Aq aqueduct bas basilar artery BOcc basioccipital bone Cb cerebellum CD cochlear duct CGn cochlear (spiral) ganglion CnF cuneiform nu DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRI dorsal raphe, interfascicular DRL dorsal raphe nu, lateral DRV dorsal raphe nu, ventral ECIC external cx inferior coll Fro/Par frontal and parietal bones HSCCA horizontal SCC IAud internal auditory meatus InG intermed gray layer SC InWh intermediate white layer SC KF Kˆlliker-Fuse nu LDTg laterodor tegmental nu ll lateral lemniscus LPAG lat periaqueductal gray LPB lateral parabrachial nu LSO lat superior olive LVPO lateroventral periolivary nu mcp middle cerebellar peduncle MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MPB medial parabrachial nu MSO medial superior olive MVPO medioventral periolivary nu ne neuroepithelium Op optic nerve layer sup coll P5 peritrigeminal zone ParP parietal plate PBG parabigeminal nu PDR posterodors raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral PnR pontine raphe nu PrS presubiculum PTg pedunculopontine tegmental py pyramidal tr RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract Sag sagulum nu ScTy scala tympani ScVe scala vestibuli sp5 spinal trigem tract SPO superior paraolivary nu Stap stapedius bone StapM stapedius muscle Su5 supratrigeminal nu trs transverse sinus VCA ventral cochlear nu, ant VeGn vestibular n ganglion Vest vestibule of the inner ear VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr VTg vent tegmental nu

Figure 87 P0 #46 6.03 mm

Op InG InWh DpG

ECIC

DpWh CIC

DLPAG

DMPAG

MiTg

LPAG

PBG

Aq

CnF

VLPAG LDTg

DRD

Bar

VTg

LDTgV

ne

ASCC

Cb

SubCA EVe

SubCD Gi P7 RIP

IRt 6RB

TempP

Pr5 sp5

PCRt

8cn

Vest ELS

IAud

Corti

VeGn 6n

HSCCA

Utr

Su5

7DL

7DI 7DM 7VI 7L LPGi 7VM

GiA

VCA

Su5

CGB 6N g7

4V

DLL

LPB vsc scp LPBE mcp MPB KF

DRV DMTg

trs

ll

RMg

StapM 7n

CD

CGn 8cn

RPa ScTy

bas

BOcc

TyBu LgCa

10Gn

ptgpal

ictd CtdB

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 6N abducens nu 6n root of abducens nerve 6RB abducens, retractor bulbi 7DI facial nu, dors intermedial 7DL facial nu, dorsolateral 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7n facial nerve 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8cn cochlear root 8th nerve 10Gn vagus nerve ganglion Aq aqueduct ASCC anterior semicirc canal Bar Barrington’s nu bas basilar artery BOcc basioccipital bone Cb cerebellum CD cochlear duct CGB central gray, beta part CGn cochlear (spiral) ganglion CIC central nu inf colliculus CnF cuneiform nu Corti organ of Corti CtdB carotid body DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral ECIC external cx inferior coll ELS endolymphatic sac EVe nu origin efferents ve n g7 genu facial nerve Gi gigantocellular reticular nu GiA gigantocellular retic, alpha HSCCA horizontal SCC IAud internal auditory meatus ictd internal carotid artery InG intermed gray layer SC InWh intermediate white layer SC IRt intermed reticular nu KF Kˆlliker-Fuse nu LDTg laterodor tegmental nu LDTgV laterodor tegmental nu, vent LgCa longus capitis muscle ll lateral lemniscus LPAG lat periaqueductal gray LPB lateral parabrachial nu LPBE lat parabrachial nu, external LPGi lat paragigantocellular nu mcp middle cerebellar peduncle MiTg microcell tegmental nu MPB medial parabrachial nu ne neuroepithelium Op optic nerve layer sup coll P7 perifacial zone PBG parabigeminal nu PCRt parvicell reticular nu Pr5 principal sensory trigem nu ptgpal pterygopalatine n RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu scp superior Cb peduncle ScTy scala tympani sp5 spinal trigem tract StapM stapedius muscle Su5 supratrigeminal nu SubCA subcoeruleus nu, alpha SubCD subcoeruleus nu, dorsal TempP temporal bone, petrous trs transverse sinus TyBu tympanic bulla Utr utricle VCA ventral cochlear nu, ant VeGn vestibular n ganglion Vest vestibule of the inner ear VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr VTg vent tegmental nu

Figure 88 P0 #47 6.15 mm

SC ECIC DLPAG

DMPAG

CIC LPAG

Aq

DRD

LDTg scp

LPB

SuVe

VTg

LPBE

Bar DRV DMTg

IRt RIP Gi

RMg RPa py

mcp Cb

SubC MVeMC MVePC

SGe EVe CGA 4V 7n 6N mlf CGG

GiA

DLL

MPB

LDTgV mlf

MiTg

CnF

VLPAG

LPGi

VCA

Su5 Pr5 PCRtA Su5

sp5

8n

SuS 7DM 7DI 7L 7VI 7VM

rs A5

bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 6N abducens nu 7DI facial nu, dors intermedial 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7n facial nerve 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8n vestibulocochlear nerve A5 A5 noradrenaline cells Aq aqueduct Bar Barrington’s nu bas basilar artery Cb cerebellum CGA central gray, alpha part CGG central gray, gamma part CIC central nu inf colliculus CnF cuneiform nu DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral ECIC external cx inferior coll EVe nu origin efferents ve n Gi gigantocellular reticular nu GiA gigantocellular retic, alpha IRt intermed reticular nu LDTg laterodor tegmental nu LDTgV laterodor tegmental nu, vent LPAG lat periaqueductal gray LPB lateral parabrachial nu LPBE lat parabrachial nu, external LPGi lat paragigantocellular nu mcp middle cerebellar peduncle MiTg microcell tegmental nu mlf med longitudinal fasciculus MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul PCRtA parvicell reticular nu, alpha Pr5 principal sensory trigem nu py pyramidal tr RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract SC superior colliculus scp superior Cb peduncle SGe supragenual nu sp5 spinal trigem tract Su5 supratrigeminal nu SubC subcoeruleus nu SuS superior salivatory nu SuVe superior vestibular nu VCA ventral cochlear nu, ant VLPAG ventlat periaqueductal gray VTg vent tegmental nu

Figure 89 P0 #48 6.27 mm

SC ECIC DMPAG

DLPAG

CIC

LPAG Aq CnF

VLPAG

Sag

DRD

LPB

LDTg scp DTg

LDTgV

LC

LPBE

MPB

CGO CGB Pr SGe 4V CGA g7

Bar MVePC EVe

GiA

5Sol

7SH

LPGi

7VM

VCA

PCRtA SuS

7DI 7DM

Pr5

Sol

IRt

RIP

Cb

MVeMC

sp5

DPGi Gi

Sp5O

HSCCA 8n

Utr ELS

7DL

TempP

A5

7VI 7L

7n 8vn

6n

RMg RPa py

ASCC

scp

SuVe

PDTg

mcp

CD

StapM

bas ScTy BOcc LgCa

CtdB

TyBu ictd

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6n root of abducens nerve 7DI facial nu, dors intermedial 7DL facial nu, dorsolateral 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7n facial nerve 7SH facial motor nu, stylohyoid 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8n vestibulocochlear nerve 8vn vestibular root of 8th nerve A5 A5 noradrenaline cells Aq aqueduct ASCC anterior semicirc canal Bar Barrington’s nu bas basilar artery BOcc basioccipital bone Cb cerebellum CD cochlear duct CGA central gray, alpha part CGB central gray, beta part CGO central gray, nu O CIC central nu inf colliculus CnF cuneiform nu CtdB carotid body DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DPGi dors paragigantocellular nu DRD dorsal raphe nu, dorsal DTg dorsal tegmental nu ECIC external cx inferior coll ELS endolymphatic sac EVe nu origin efferents ve n g7 genu facial nerve Gi gigantocellular reticular nu GiA gigantocellular retic, alpha HSCCA horizontal SCC ictd internal carotid artery IRt intermed reticular nu LC locus coeruleus LDTg laterodor tegmental nu LDTgV laterodor tegmental nu, vent LgCa longus capitis muscle LPAG lat periaqueductal gray LPB lateral parabrachial nu LPBE lat parabrachial nu, external LPGi lat paragigantocellular nu mcp middle cerebellar peduncle MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul PCRtA parvicell reticular nu, alpha PDTg posterodors tegmental nu Pr prepositus nu Pr5 principal sensory trigem nu py pyramidal tr RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu Sag sagulum nu SC superior colliculus scp superior Cb peduncle ScTy scala tympani SGe supragenual nu Sol nu of solitary tract sp5 spinal trigem tract Sp5O spinal trigeml nu, oral StapM stapedius muscle SuS superior salivatory nu SuVe superior vestibular nu TempP temporal bone, petrous TyBu tympanic bulla Utr utricle VCA ventral cochlear nu, ant VLPAG ventlat periaqueductal gray

Figure 90 P0 #49 6.39 mm

SC Com

DCIC

DLPAG

DMPAG

ECIC

CIC LPAG

Aq

DRC DTgP

ASCC

LDTg

mcp

LPB MPB

scp

Bar LC DTgC

Sph

Cb SuVe

PDTg Pr

VCA 8n sp5

Sol 5Sol

DPGi

LR4V

MVeMC

MVePC

4V

Sag

CnF

VLPAG

IRt

PCRtA

Sp5O

Utr

HSCC

ELS Gi GiA RMg

LPGi

CD 7n

ScTy

C1 py

RPa

StapM

8n

7N

StyMF

ScTy

bas

TyC

I9Gn

TyBu

BOcc ictd 10Gn

CtdB

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 7N facial nu 7n facial nerve 8n vestibulocochlear nerve 10Gn vagus nerve ganglion Aq aqueduct ASCC anterior semicirc canal Bar Barrington’s nu bas basilar artery BOcc basioccipital bone C1 C1 adrenaline cells Cb cerebellum CD cochlear duct CIC central nu inf colliculus CnF cuneiform nu Com commissural nu inf colliculus CtdB carotid body DCIC dors cx inf colliculus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DPGi dors paragigantocellular nu DRC dorsal raphe nu, caudal DTgC dors tegmental nu, central DTgP dors tegmental nu, pericent ECIC external cx inferior coll ELS endolymphatic sac Gi gigantocellular reticular nu GiA gigantocellular retic, alpha HSCC horizontal semicircular canal I9Gn inferior ganglion 9n ictd internal carotid artery IRt intermed reticular nu LC locus coeruleus LDTg laterodor tegmental nu LPAG lat periaqueductal gray LPB lateral parabrachial nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle mcp middle cerebellar peduncle MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul PCRtA parvicell reticular nu, alpha PDTg posterodors tegmental nu Pr prepositus nu py pyramidal tr RMg raphe magnus nu RPa raphe pallidus nu Sag sagulum nu SC superior colliculus scp superior Cb peduncle ScTy scala tympani Sol nu of solitary tract sp5 spinal trigem tract Sp5O spinal trigeml nu, oral Sph sphenoid nu StapM stapedius muscle StyMF stylomastoid foramen SuVe superior vestibular nu TyBu tympanic bulla TyC tympanic cavity Utr utricle VCA ventral cochlear nu, ant VLPAG ventlat periaqueductal gray

Figure 91 P0 #50 6.51 mm

SC Com

DCIC

DMPAG DLPAG

CIC

ECIC

LPAG CnF

Aq Me5

VLPAG

Sim

MPB LDTg

LPB

mcp scp

me5

DTg

LC

PDTg

PFl

IRt

DPGi Gi LPGi GiA

plf

LR4V

LVe VCA

MVeMC Sol 5Sol

Pr

ASCC

Fl

icp

MVePC

4V

Hem

SuVe

Bar

Sph

trs

Sag

PCRtA

8vn VCP HSCC

ELS Sp5I

7DI 7DL 7DM 7VI 7L 7VM

StapM

sp5 8n

CD ScTy 7n

RMg RPa py bas I9Gn ictd

ty9

CtdB ectd

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 7DI facial nu, dors intermedial 7DL facial nu, dorsolateral 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7n facial nerve 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8n vestibulocochlear nerve 8vn vestibular root of 8th nerve Aq aqueduct ASCC anterior semicirc canal Bar Barrington’s nu bas basilar artery CD cochlear duct CIC central nu inf colliculus CnF cuneiform nu Com commissural nu inf colliculus CtdB carotid body DCIC dors cx inf colliculus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DPGi dors paragigantocellular nu DTg dorsal tegmental nu ECIC external cx inferior coll ectd external carotid artery ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha Hem hemisphere of cerebellum HSCC horizontal semicircular canal I9Gn inferior ganglion 9n icp inf cerebellar peduncle ictd internal carotid artery IRt intermed reticular nu LC locus coeruleus LDTg laterodor tegmental nu LPAG lat periaqueductal gray LPB lateral parabrachial nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu mcp middle cerebellar peduncle Me5 mesencephalic trigem nu me5 mesencephalic trigem tract MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul PCRtA parvicell reticular nu, alpha PDTg posterodors tegmental nu PFl paraflocculus plf posterolateral fissure Pr prepositus nu py pyramidal tr RMg raphe magnus nu RPa raphe pallidus nu Sag sagulum nu SC superior colliculus scp superior Cb peduncle ScTy scala tympani Sim simple lobule Sol nu of solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sph sphenoid nu StapM stapedius muscle SuVe superior vestibular nu trs transverse sinus ty9 tympanic branch of 9n VCA ventral cochlear nu, ant VCP vent cochlear nu, posterior VLPAG ventlat periaqueductal gray

Figure 92 P0 #51 6.63 mm

SC DCIC

Com

ECIC DMPAG

DLPAG

CIC

LPAG

EGL

Sag Aq

CnF

VLPAG

Sim scp

LPB

ne DTg

LDTg

mcp

MPB

PFl

Me5 SuVe

IRt Gi

GrC

SpVe X

5Sol

DPGi

PCRt

PFlCv

LR4V

LVe

MVeMC IS Sol

Pr

Fl icp

MVePC

ne

ASCC

plf

Sph 4V

ParP trs

Hem

ELS

VCP sp5 Sp5I

7SH

CGn

tz 8cn

GiV RMg RPa py

LPGi

HSCC

TempP

Utr

StapM

7N

7n

C1

Rc I9Gn

bas ty9

Rc

occ 11n ictd StM

CtdB ectd

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 7N facial nu 7n facial nerve 7SH facial motor nu, stylohyoid 8cn cochlear root 8th nerve 11n root of accessory nerve Aq aqueduct ASCC anterior semicirc canal bas basilar artery C1 C1 adrenaline cells CGn cochlear (spiral) ganglion CIC central nu inf colliculus CnF cuneiform nu Com commissural nu inf colliculus CtdB carotid body DCIC dors cx inf colliculus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DPGi dors paragigantocellular nu DTg dorsal tegmental nu ECIC external cx inferior coll ectd external carotid artery EGL external granular layer Cb ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu GiV gigantocellular retic, vent GrC granule cell, cochlear nu Hem hemisphere of cerebellum HSCC horizontal semicircular canal I9Gn inferior ganglion 9n icp inf cerebellar peduncle ictd internal carotid artery IRt intermed reticular nu IS inferior salivatory nu LDTg laterodor tegmental nu LPAG lat periaqueductal gray LPB lateral parabrachial nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu mcp middle cerebellar peduncle Me5 mesencephalic trigem nu MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul ne neuroepithelium occ occipital artery ParP parietal plate PCRt parvicell reticular nu PFl paraflocculus PFlCv parafloccular cavity plf posterolateral fissure Pr prepositus nu py pyramidal tr Rc Reichert’s cartilage RMg raphe magnus nu RPa raphe pallidus nu Sag sagulum nu SC superior colliculus scp superior Cb peduncle Sim simple lobule Sol nu of solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sph sphenoid nu SpVe spinal vestibular nu StapM stapedius muscle StM sternomastoid muscle SuVe superior vestibular nu TempP temporal bone, petrous trs transverse sinus ty9 tympanic branch of 9n tz trapezoid body Utr utricle VCP vent cochlear nu, posterior VLPAG ventlat periaqueductal gray X nu X

Figure 93 P0 #52 6.75 mm

Com

SC

DCIC

CIC

ECIC

PAG Aq

EGL CnF

ne

ParP

Sim trs

Hem LPB 2/3Cb Lat

Int CG

VeCb

plf LatPC LVe

4V

Pr

SpVe SolVL

Fl GrC LR4V

Y

MVePC MVeMC IS Sol

ASCC

PFl

icp

DC

X

ELS

PFlCv

ne

5Sol DPGi

VCP IRt

ROb

PCRt

CCrus

Sp5I

Gi

Bo

Utr CGn

rs

C1/RVL GiV RPa

py

HSCC

HSCC

AmbC

LPGi

JugF S9Gn

bas I9Gn

ty9 9/10n 9n

StM occ

BOcc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

11n

0

0.2

0.4

0.6

0.8

1.0 mm

2/3Cb 2nd/3rd cerebellarlobules 4V 4th ventricle 5Sol trigeminal-solitary trans 9/10n glossopharyngeal & vagus 9n glossopharyngeal nerve 11n root of accessory nerve AmbC ambiguus nu, compact part Aq aqueduct ASCC anterior semicirc canal bas basilar artery Bo Botzinger complex BOcc basioccipital bone C1/RVL C1/rostral ventlat retic nu CCrus common crus CG central gray CGn cochlear (spiral) ganglion CIC central nu inf colliculus CnF cuneiform nu Com commissural nu inf colliculus DC dorsal cochlear nu DCIC dors cx inf colliculus DPGi dors paragigantocellular nu ECIC external cx inferior coll EGL external granular layer Cb ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu GiV gigantocellular retic, vent GrC granule cell, cochlear nu Hem hemisphere of cerebellum HSCC horizontal semicircular canal I9Gn inferior ganglion 9n icp inf cerebellar peduncle Int interposed cerebellar nu IRt intermed reticular nu IS inferior salivatory nu JugF jugular foramen Lat lateral (dentate) Cb nu LatPC lat Cb nu, parvicell LPB lateral parabrachial nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul ne neuroepithelium occ occipital artery PAG periaqueductal gray ParP parietal plate PCRt parvicell reticular nu PFl paraflocculus PFlCv parafloccular cavity plf posterolateral fissure Pr prepositus nu py pyramidal tr ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract S9Gn superior ganglion 9n SC superior colliculus Sim simple lobule Sol nu of solitary tract SolVL nu sol tract, ventrolateral Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu StM sternomastoid muscle trs transverse sinus ty9 tympanic branch of 9n Utr utricle VCP vent cochlear nu, posterior VeCb vestibulocerebellar nu X nu X Y nu Y

Figure 94 P0 #53 6.87 mm

Com

SC

IC

PAG Aq

EGL ne

CnF

Sim Hem

EGL

4/5Cb 1Cb

Med A4

GrC SpVe

MVeMC IS Sol

ROb

IRt

Mx X 5Sol sp5 PCRt Sp5I

LR4V

8n DC VCP

ELS

PFlCv

ne CCrus

AmbC Gi Bo

GiV IOM RPa py

ASCC

Fl

Y

MVePC

DPGi mlf C2

PFl plf

LatPC

4V

Pr

Lat

Int

9/10/11n

LPGi IOPr

HSCC rs Utr

JugF

C1/RVL

bas

S9Gn 9/10/11n

I9Gn

BOcc

ty9 I9Gn

StM

11n CtdB

9n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

12n

0

0.2

0.4

0.6

0.8

1.0 mm

1Cb 1st cerebellar lobule 4/5Cb 4th/5th cerebellar lobules 4V 4th ventricle 5Sol trigeminal-solitary trans 8n vestibulocochlear nerve 9/10/11n 9n, 10n, and 11n 9n glossopharyngeal nerve 11n root of accessory nerve 12n root of hypoglossal nerve A4 A4 noradrenaline cells AmbC ambiguus nu, compact part Aq aqueduct ASCC anterior semicirc canal bas basilar artery Bo Botzinger complex BOcc basioccipital bone C1/RVL C1/rostral ventlat retic nu C2 C2 adrenaline cells CCrus common crus CnF cuneiform nu Com commissural nu inf colliculus CtdB carotid body DC dorsal cochlear nu DPGi dors paragigantocellular nu EGL external granular layer Cb ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu GiV gigantocellular retic, vent GrC granule cell, cochlear nu Hem hemisphere of cerebellum HSCC horizontal semicircular canal I9Gn inferior ganglion 9n IC inferior colliculus Int interposed cerebellar nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu IS inferior salivatory nu JugF jugular foramen Lat lateral (dentate) Cb nu LatPC lat Cb nu, parvicell LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle Med medial cerebellar nu mlf med longitudinal fasciculus MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul Mx matrix region medulla ne neuroepithelium PAG periaqueductal gray PCRt parvicell reticular nu PFl paraflocculus PFlCv parafloccular cavity plf posterolateral fissure Pr prepositus nu py pyramidal tr ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract S9Gn superior ganglion 9n SC superior colliculus Sim simple lobule Sol nu of solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu StM sternomastoid muscle ty9 tympanic branch of 9n Utr utricle VCP vent cochlear nu, posterior X nu X Y nu Y

Figure 95 P0 #54 6.99 mm

SC

Com PAG

IC

Aq ParP

ne

Sim

6Cb Hem 1Cb

EGL

Med

Int

PFl

Lat

4V

plf

ASCC

Fl MVe In 10N Sol

PFlCv HSCC

IRt PCRt

Li Gi

sp5 Sp5I

icp HSCC

AmbC PrBo

IOM py

ELS

5Sol Mx

Ro

GiV

DC X

sol

12N

ROb

LR4V

SpVe FVe

Pr

HSCC rs

LPGi IOD IOPr

C1/CVL

PSCC JugF S9Gn

9/10/11n

bas RPa occ 9n

MasM

BOcc StM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1Cb 1st cerebellar lobule 4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 9/10/11n 9n, 10n, and 11n 9n glossopharyngeal nerve 10N dorsal motor nu of vagus 12N hypoglossal nu AmbC ambiguus nu, compact part Aq aqueduct ASCC anterior semicirc canal bas basilar artery BOcc basioccipital bone C1/CVL C1/caudoventrolat retic Com commissural nu inf colliculus DC dorsal cochlear nu EGL external granular layer Cb ELS endolymphatic sac Fl flocculus FVe F cell group vestib Gi gigantocellular reticular nu GiV gigantocellular retic, vent Hem hemisphere of cerebellum HSCC horizontal semicircular canal IC inferior colliculus icp inf cerebellar peduncle In intercalated nu medulla Int interposed cerebellar nu IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu JugF jugular foramen Lat lateral (dentate) Cb nu Li linear nu of the medulla LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle MasM masseter muscle Med medial cerebellar nu MVe medial vestibular nu Mx matrix region medulla ne neuroepithelium occ occipital artery PAG periaqueductal gray ParP parietal plate PCRt parvicell reticular nu PFl paraflocculus PFlCv parafloccular cavity plf posterolateral fissure Pr prepositus nu PrBo pre-Botzinger complex PSCC post semicircular canal py pyramidal tr Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract S9Gn superior ganglion 9n SC superior colliculus Sim simple lobule Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu StM sternomastoid muscle X nu X

Figure 96 P0 #55 7.11 mm

SC PAG

IC

Aq Sim EGL

Hem

6Cb

pfs Med 10Cb

Lat

Int

PFl plf

plf Fl

4V

ELS LR4V

MVe

Z

SpVe

Pr 10N

Sol

X

sol

IRt

Ro

sp5 HSCC

Sp5C

AmbC

IOM IOD

PSCC

PrBo CVL/C1 LPGi

RPa bas

Sp5I PCRt Li

Gi

py IOM

PFlCV

5Sol

In 12N

ROb

PSCC

ne icp DC

S9Gn ijugv 9/10/11n

12C IOPr

12n

JugF

occ

MasM

BOcc StM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 9/10/11n 9n, 10n, and 11n 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12C hypoglossal canal 12N hypoglossal nu 12n root of hypoglossal nerve AmbC ambiguus nu, compact part Aq aqueduct bas basilar artery BOcc basioccipital bone CVL/C1 caudoventrolat retic/C1 DC dorsal cochlear nu EGL external granular layer Cb ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu Hem hemisphere of cerebellum HSCC horizontal semicircular canal IC inferior colliculus icp inf cerebellar peduncle ijugv internal jugular vein In intercalated nu medulla Int interposed cerebellar nu IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu JugF jugular foramen Lat lateral (dentate) Cb nu Li linear nu of the medulla LPGi lat paragigantocell ret LR4V lat recess 4th ventricle MasM masseter muscle Med medial cerebellar nu MVe medial vestibular nu ne neuroepithelium occ occipital artery PAG periaqueductal gray PCRt parvicell reticular nu PFl paraflocculus PFlCv parafloccular cavity pfs parafloccular sulcus plf posterolateral fissure Pr prepositus nu PrBo pre-Botzinger complex PSCC post semicircular canal py pyramidal tr Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu S9Gn superior ganglion 9n SC superior colliculus Sim simple lobule Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu StM sternomastoid muscle X nu X Z nu Z

Figure 97 P0 #56 7.23 mm

SC

IC

PAG Aq

EGL

Sim

ne

Hem

6Cb

ParP pfs Med

9Cb

trs

Int

Lat

PFl

10Cb

ELS

plf Fl

4V

MVe 10N

SpVe

sol Sol

LR4V

ECu

Mx 5Sol

PSCC

icp Sp5I

12N PCRt

ROb

sp5

IRt

Ro Gi

AmbSC

LRt IOD RPa

RVRG LPGi

Sp5C 9/10/11n

rs LRtPC C1/A1

Occ

12C IOPr

ijugv JugF

IOM bas

PSCC

S9Gn

12n 12n

occ StM

BOcc

11n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 9/10/11n 9n, 10n, and 11n 9Cb 9th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 11n root of accessory nerve 12C hypoglossal canal 12N hypoglossal nu 12n root of hypoglossal nerve AmbSC ambiguus nu, subcompact Aq aqueduct bas basilar artery BOcc basioccipital bone C1/A1 adren/ noradrenaline cells ECu external cuneate nu EGL external granular layer Cb ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu Hem hemisphere of cerebellum IC inferior colliculus icp inf cerebellar peduncle ijugv internal jugular vein Int interposed cerebellar nu IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu JugF jugular foramen Lat lateral (dentate) Cb nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LRt lateral reticular nu LRtPC lat reticular nu, parvicellular Med medial cerebellar nu MVe medial vestibular nu Mx matrix region medulla ne neuroepithelium Occ occipital bone occ occipital artery PAG periaqueductal gray ParP parietal plate PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure PSCC post semicircular canal Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract RVRG rost vent respiratory S9Gn superior ganglion 9n SC superior colliculus Sim simple lobule Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu StM sternomastoid muscle trs transverse sinus

Figure 98 P0 #57 7.35 mm

SC IC Sim

EGL Hem pfs

ne 6Cb Med

PFl

Int

10Cb

ELS

Fl LR4V SpVe 4V MVe ECu Mx sol icp PSol Sol 10N 5Sol Pa5 Sp5I 12N IRt PCRt Gr

Ro ROb

AmbL Sp5C RVRG C1/A1 LRt

IOM RPa

IOM

sp5

Gi

9/10/11n LRtPC 12n 12C

IOD IOPr

12n

bas Occ

Atlas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 9/10/11n 9n, 10n, and 11n 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12C hypoglossal canal 12N hypoglossal nu 12n root of hypoglossal nerve AmbL ambiguus nu, loose part Atlas atlas bas basilar artery C1/A1 adren/ noradrenaline cells ECu external cuneate nu EGL external granular layer Cb ELS endolymphatic sac Fl flocculus Gi gigantocellular reticular nu Gr gracile nu Hem hemisphere of cerebellum IC inferior colliculus icp inf cerebellar peduncle Int interposed cerebellar nu IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu LR4V lat recess 4th ventricle LRt lateral reticular nu LRtPC lat reticular nu, parvicellular Med medial cerebellar nu MVe medial vestibular nu Mx matrix region medulla ne neuroepithelium Occ occipital bone Pa5 paratrigeminal nu PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus PSol parasolitary nu Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu RVRG rost vent respiratory SC superior colliculus Sim simple lobule Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu

Figure 99 P0 #58 7.47 mm

IC

Sim 6Cb Hem EGL

Med

pfs ELS

10Cb PFl 4V MVe sol

Gr

Cu

ECu Mx PSol 5Sol Sol Sp5I

10N

icp

occs PSCC

PCRt 12N

CeC

ROb

Gi

IOK IOD

IOBe

IRt

Sp5C

AmbL RVRG LRt

sig sp5

rs LRtPC

IOC IOB IOA

bas

12n

py

Occ

Ptd

Atlas

Axis

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu 12n root of hypoglossal nerve AmbL ambiguus nu, loose part Atlas atlas Axis axis (C2 vertebra) bas basilar artery CeC central amyg nu, capsular Cu cuneate nu ECu external cuneate nu EGL external granular layer Cb ELS endolymphatic sac Gi gigantocellular reticular nu Gr gracile nu Hem hemisphere of cerebellum IC inferior colliculus icp inf cerebellar peduncle IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOD inf olive, dorsal nu IOK inf olive, cap of Kooy med nu IRt intermed reticular nu LRt lateral reticular nu LRtPC lat reticular nu, parvicellular Med medial cerebellar nu MVe medial vestibular nu Mx matrix region medulla Occ occipital bone occs occipital sinus PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus PSCC post semicircular canal PSol parasolitary nu Ptd parotid gland py pyramidal tr ROb raphe obscurus nu rs rubrospinal tract RVRG rost vent respiratory sig sigmoid sinus Sim simple lobule Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar

Figure 100 P0 #59 7.59 mm

IC EGL 6Cb

Crus1

pms

Hem pfs PFl

10Cb Gr cu Cu ECu CuR PSol Mx sol Sol 5Sol

4V

occs Pa5 Sp5I

10N MdD

sp5

TempP

12N IRt ROb

Sp5C

MdV RAmb IOK

IOD

IOBe

LRt

IOC IOB IOA

RPa

RVRG PrLSp

py vert

Occ C1/A1

12n

DAx

Atlas Axis Ptd

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu 12n root of hypoglossal nerve Atlas atlas Axis axis (C2 vertebra) C1/A1 adren/ noradrenaline cells Crus1 crus 1 ansiform lobule Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part DAx dens of the axis ECu external cuneate nu EGL external granular layer Cb Gr gracile nu Hem hemisphere of cerebellum IC inferior colliculus IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOD inf olive, dorsal nu IOK inf olive, cap of Kooy med nu IRt intermed reticular nu LRt lateral reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent Mx matrix region medulla Occ occipital bone occs occipital sinus Pa5 paratrigeminal nu PFl paraflocculus pfs parafloccular sulcus pms paramedian sulcus PrLSp pre lateral spinal PSol parasolitary nu Ptd parotid gland py pyramidal tr RAmb retroambiguus nu ROb raphe obscurus nu RPa raphe pallidus nu RVRG rost vent respiratory Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar TempP temporal bone, petrous vert vertebral art

Figure 101 P0 #60 7.71 mm

IC

Crus1

6Cb

EGL

pms Hem pfs 8Cb

PFl

9Cb

10Cb

AP

cu

Cu

Gr

ECu

CuR

Sol

Mx sol Sp5C sp5

10N MdD

cc

CeCv 12N

mlx

dsc IRt Sp5I

IOK MdV RAmb IOBe IOC IOB IOA py

rs

A1 LRt 12n

vert

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

6Cb 6th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu 12n root of hypoglossal nerve A1 A1 noradrenaline cells AP area postrema cc corpus callosum CeCv central cervical nu Crus1 crus 1 ansiform lobule Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part dsc dorsal spinocereb tract ECu external cuneate nu EGL external granular layer Cb Gr gracile nu Hem hemisphere of cerebellum IC inferior colliculus IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOK inf olive, cap of Kooy med nu IRt intermed reticular nu LRt lateral reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent mlx med lemniscus decussation Mx matrix region medulla PFl paraflocculus pfs parafloccular sulcus pms paramedian sulcus py pyramidal tr RAmb retroambiguus nu rs rubrospinal tract Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar vert vertebral art

Figure 102 P0 #61 7.83 mm

IC 6Cb

Crus2 PM

7Cb

EGL

Cop 8Cb

PFl

9Cb

10Cb cu

Cu

MnA Gr

CuR

Mx

sol

sp5

Sol MdD

10N

12N

Sp5C

IRt dsc MdV RAmb 11N

A1

rs

LRt pyx IOB vert

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

6Cb 6th cerebellar lobule 7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 11N accessory nerve nu 12N hypoglossal nu A1 A1 noradrenaline cells Cop copula pyramis Crus2 crus 2 ansiform lobule Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part dsc dorsal spinocereb tract EGL external granular layer Cb Gr gracile nu IC inferior colliculus IOB inf olive, subnu B med nu IRt intermed reticular nu LRt lateral reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent MnA median access nu medulla Mx matrix region medulla PFl paraflocculus PM paramedian lobule pyx pyramidal decussation RAmb retroambiguus nu rs rubrospinal tract Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal vert vertebral art

Figure 103 P0 #62 7.95 mm

7Cb Crus2

PM EGL

8Cb

gr

Gr Mx

Cop

cu

Cu

CuR Mx sp5

sol Sol 10N

MdD

Sp5C

IRt CeCv

dsc A1 rs

MdV 11N pyx vmnf

SSp Atlas AtAx

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 10N dorsal motor nu of vagus 11N accessory nerve nu A1 A1 noradrenaline cells AtAx atlantoaxial joint Atlas atlas CeCv central cervical nu Cop copula pyramis Crus2 crus 2 ansiform lobule Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part dsc dorsal spinocereb tract EGL external granular layer Cb Gr gracile nu gr gracile fasciculus IRt intermed reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent Mx matrix region medulla PM paramedian lobule pyx pyramidal decussation rs rubrospinal tract Sol nu of solitary tract sol solitary tract sp5 spinal trigem tract Sp5C spinal trigem nu, caudal SSp supraspinal nucleus vmnf ventral median fissure

Figure 104 P6 #1 0.99 mm

Fro

EPl

IPL

MiA

Mi

ne

Gl

GrO

OV

EPl

SuspLig

ON 1n OF RGn InPl

SOb ne

CrP

Vent Pig

EthB EthB

NSpt MRec

NasC

HardG 5mx

MxB NasC

EnO MxB

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division CrP cribriform plate ethmoid EnO enamel organ EPl ext plexiform layer olf bulb EthB ethmoid bone Fro frontal bone Gl glomerular layer olf bulb GrO granular cell layer olf bulb HardG Harderian gland InPl inner plexiform layer IPL interpedunc nu, lat subnu Mi mitral cell layer olf bulb MiA mitral cell layer acc olf bulb MRec medial rectus muscle MxB maxillary bone NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer ON olfactory nerve layer OV olfactory ventricle Pig pigment layer of the eye RGn ganglion cell layer SOb superior oblique muscle SuspLig suspensory ligament Vent ventricular space eye

Figure 105 P6 #2 1.35 mm

FrA MO VO

LO vn MiA dlo

Fro AOE

AOL aci

SuspLig

Mi

AOD

lo

ne

OV

GrO

Gl

AOV EPl

RGn

ne

ON

OF

Cornea

InPl

Pig

1n

Vent EthB

Lens

NasC

HardG NSpt 5mx

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

1n olfactory nerve 5mx 5n, maxillary division aci ant commiss, intrabulbar AOD ant olfactory nu, dors AOE ant olfactory nu, ext AOL ant olfactory nu, lat AOV ant olfactory nu, ventral Cornea cornea dlo dorsal lat olfactory tract EPl ext plexiform layer olf bulb EthB ethmoid bone FrA frontal assocn cortex Fro frontal bone Gl glomerular layer olf bulb GrO granular cell layer olf bulb HardG Harderian gland InPl inner plexiform layer Lens lens LO lateral orbital cx lo lateral olfactory tract Mi mitral cell layer olf bulb MiA mitral cell layer acc olf bulb MO medial orbital cx NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer ON olfactory nerve layer OV olfactory ventricle Pig pigment layer of the eye RGn ganglion cell layer SuspLig suspensory ligament Vent ventricular space eye vn vomeronasal n VO ventral orbital cx

Figure 106 P6 #3 1.71 mm

FrA

PrL

DLO VO

MO

LO

AOD

Mi AOM OV EPl

aci

AOL

ne

GrO IPl

AOV

Gl

ON

AOE

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

aci ant commiss, intrabulbar AOD ant olfactory nu, dors AOE ant olfactory nu, ext AOL ant olfactory nu, lat AOM ant olfactory nu, medial AOV ant olfactory nu, ventral DLO dorsolat orbital cortex EPl ext plexiform layer olf bulb FrA frontal assocn cortex Gl glomerular layer olf bulb GrO granular cell layer olf bulb IPl IP layer olf bulb LO lateral orbital cx Mi mitral cell layer olf bulb MO medial orbital cx ne neuroepithelium ON olfactory nerve layer OV olfactory ventricle PrL prelimbic cx VO ventral orbital cx

Figure 107 P6 #4 1.83 mm

M2 PrL M1

MO Fr3 LO

VO

AID AOD

AIV

DTT

DEn aci

AOL

ne

OV AOM GrO Gl

AOV

lo

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

EPl

0

0.2

0.4

0.6

0.8

1.0 mm

aci ant commiss, intrabulbar AID agranular insular cx, dorsal AIV agranular insular cx, vent AOD ant olfactory nu, dors AOL ant olfactory nu, lat AOM ant olfactory nu, medial AOV ant olfactory nu, ventral DEn dorsal endopiriform nu DTT dorsal tenia tecta EPl ext plexiform layer olf bulb Fr3 frontal cx, area 3 Gl glomerular layer olf bulb GrO granular cell layer olf bulb LO lateral orbital cx lo lateral olfactory tract M1 primary motor cx M2 secondary motor cx MO medial orbital cx ne neuroepithelium OV olfactory ventricle PrL prelimbic cx VO ventral orbital cx

Figure 108 P6 #5 1.95 mm

M2

Cg1

M1

PrL

Fr3

Fro

AID MO VO AIV LO

DTr DEn DTT

IEn ne OV

rf

AOVP

3

Pig

2 Pir1

Vent

VTT

lo ne LPS

InPl

Lens

EthB

RGn SRec

OF

MidM

EthB

2n a MRec

NSpt NasC

5mx

NasC

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division a artery AID agranular insular cx, dorsal AIV agranular insular cx, vent AOVP ant olfactory, ventropost Cg1 cingulate cortex, area 1 DEn dorsal endopiriform nu DTr dorsal transition zone DTT dorsal tenia tecta EthB ethmoid bone Fr3 frontal cx, area 3 Fro frontal bone IEn intermed endopiriform nu InPl inner plexiform layer Lens lens LO lateral orbital cx lo lateral olfactory tract LPS levator palpebrae M1 primary motor cx M2 secondary motor cx MidM middle meatus MO medial orbital cx MRec medial rectus muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer OV olfactory ventricle Pig pigment layer of the eye Pir1 piriform cx, layer 1 PrL prelimbic cx rf rhinal fissure RGn ganglion cell layer SRec superior rectus muscle Vent ventricular space eye VO ventral orbital cx VTT ventral tenia tecta

Figure 109 P6 #6 2.07 mm

M1 M2 Cg1

Fr3

S1J PrL

DI

Fro

Cl IL

AID VO

LO AIV

DEn IEn

OF

ne

OV

aca

PSphW

Pir1 lo

DTT AOVP

3

SOb Vent

DP

DTr

2 AOP 3

ne

RGn

2 VTT1

InPl LPS Lens SRec

Pig

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

2n

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex aca anterior commissure, ant AID agranular insular cx, dorsal AIV agranular insular cx, vent AOP ant olfactory nu, post AOVP ant olfactory, ventropost Cg1 cingulate cortex, area 1 Cl claustrum DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTr dorsal transition zone DTT dorsal tenia tecta Fr3 frontal cx, area 3 Fro frontal bone IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer Lens lens LO lateral orbital cx lo lateral olfactory tract LPS levator palpebrae M1 primary motor cx M2 secondary motor cx ne neuroepithelium OF optic fiber layer OV olfactory ventricle Pig pigment layer of the eye Pir1 piriform cx, layer 1 PrL prelimbic cx PSphW presphenoid wing RGn ganglion cell layer S1J prim somatosens, jaw SOb superior oblique muscle SRec superior rectus muscle Vent ventricular space eye VO ventral orbital cx VTT1 vent tenia tecta, layer 1

Figure 110 P6 #7 2.19 mm

M2 Cg1 M1 Fr3

PrL

S1J

Fro

fmi

DCl

GI

IL VCl DP

DI AIV

LO AcbSh ne

AID

OV DEn 3 Pir1

Pig Vent

DTT 2 1

AOVP

aca

rf

3

4

IEn

2 3

AOP

lo

2 VTT 1

ne LPS

InPl RGn OF

SRec

MidM

2n

NSpt cav

MRec

5mx HardG

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

NasC

SphPal

EnO

0

0.2

0.4

0.6

0.8

1.0 mm

1 layer 1 of cortex 2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 4 layer 4 of cortex 5mx 5n, maxillary division aca anterior commissure, ant AcbSh accumbens nu, shell AID agranular insular cx, dors AIV agranular insular cx, vent AOP ant olfactory nu, post AOVP ant olfactory, ventropost cav cavernous sinus Cg1 cingulate cortex, area 1 DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTT dorsal tenia tecta EnO enamel organ fmi forceps min corpus call Fr3 frontal cx, area 3 Fro frontal bone GI granular insular cx HardG Harderian gland IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer LO lateral orbital cx lo lateral olfactory tract LPS levator palpebrae M1 primary motor cx M2 secondary motor cx MidM middle meatus MRec medial rectus muscle NasC nasal cavity ne neuroepithelium NSpt nasal septum OF optic fiber layer OV olfactory ventricle Pig pigment layer of the eye Pir1 piriform cx, layer 1 PrL prelimbic cx rf rhinal fissure RGn ganglion cell layer S1J prim somatosens, jaw SphPal sphenopalatine ganglion SRec superior rectus muscle VCl vent part claustrum Vent ventricular space eye VTT ventral tenia tecta

Figure 111 P6 #8 2.31 mm

M2 Cg1

M1 Fr3

PrL

fmi

S1J

IL DCl GI

DP

CPu VCl ne

DI AID

DTT

OV

AIV DEn aca 3

Nv

AcbSh

IEn

Pir1 2

AOP

lo Tu

ICj

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

ICj

0.6

0.8

1.0 mm

2 layer 2 of cortex 3 layer 3 of cortex aca anterior commissure, ant AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent AOP ant olfactory nu, post Cg1 cingulate cortex, area 1 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTT dorsal tenia tecta fmi forceps min corpus call Fr3 frontal cx, area 3 GI granular insular cx ICj islands of Calleja IEn intermed endopiriform nu IL infralimbic cortex lo lateral olfactory tract M1 primary motor cx M2 secondary motor cx ne neuroepithelium Nv navicular nu basal forebrain OV olfactory ventricle Pir1 piriform cx, layer 1 PrL prelimbic cx rf rhinal fissure S1J prim somatosens, jaw Tu olfactory tubercle VCl vent part claustrum

Figure 112 P6 #9 2.43 mm

M2 Cg1 M1

cg PrL

fmi S1J

IL

dcw Fro

DTT

CPu

VCl

DI

DP

ne

DCl

GI

LV

AID

LSI AIV

SHi

DEn AcbC

aca 3

rf

IEn

2 Pir1

Nv

AcbSh

AOP

azac

mfb

lo Vent

VP

3

ICj

ICj

2 Tu1

InPl Eye

OptF

SRec

ne Pig

2n PSph LRec IRec

MRec ophv 5mx

HardG

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

SphPal

0

0.2

NasC

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent AOP ant olfactory nu, post azac azygous ant cerebral art cg cingulum Cg1 cingulate cortex, area 1 CPu caudate putamen (striatum) DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTT dorsal tenia tecta Eye eye fmi forceps min corpus call Fro frontal bone GI granular insular cx HardG Harderian gland ICj islands of Calleja IEn intermed endopiriform nu IL infralimbic cortex InPl inner plexiform layer IRec inferior rectus muscle lo lateral olfactory tract LRec lat rectus muscle LSI lat septal nu, intermed LV lateral ventricle M1 primary motor cx M2 secondary motor cx mfb med forebrain bundle MRec medial rectus muscle NasC nasal cavity ne neuroepithelium Nv navicular nu basal forebrain ophv ophthalmic vein OptF optic foramen Pig pigment layer of the eye Pir1 piriform cx, layer 1 PrL prelimbic cx PSph presphenoid bone rf rhinal fissure S1J prim somatosens, jaw SHi septohippocampal nu SphPal sphenopalatine ganglion SRec superior rectus muscle Tu1 olfactory tubercle, layer 1 VCl vent part claustrum Vent ventricular space eye VP ventral pallidum

Figure 113 P6 #10 2.55 mm

M2 M1 Cg1 S1FL S1DZ PrL

cg fmi

S1J

IL

ec

DP

ne S2

Fro

DCl

G1

DTT

CPu LV LSV

VCl

DI

LSI

SHi

AID DEn

AIV

AcbC

aca

Nv

3

rf 2

ICjM

IEn

Pir1 Pig

AcbSh

lo

VP

VP

Vent Tu1

2

azac

3

ne OptF 2n PSph HardG

cav 5mx

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent azac azygous ant cerebral art cav cavernous sinus cg cingulum Cg1 cingulate cortex, area 1 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx DTT dorsal tenia tecta ec external capsule fmi forceps min corpus call Fro frontal bone Gi gigantocell reticular nu HardG Harderian gland ICjM islands of Calleja, major IEn intermed endopiriform nu IL infralimbic cortex lo lateral olfactory tract LSI lat septal nu, intermed LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx ne neuroepithelium Nv navicular nu basal forebrain OptF optic foramen Pig pigment layer of the eye Pir1 piriform cx, layer 1 PrL prelimbic cx PSph presphenoid bone rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw S2 2ary somatosensory cx SHi septohippocampal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum Vent ventricular space eye VP ventral pallidum

Figure 114 P6 #11 2.67 mm

M2 M1 Cg1 S1DZ

S1FL PrL

cg S1J

IL fmi ne

DP

IG

ec

S2

LV

LSD SHi

GI

DCl

DI

CPu LSI

LSV

VCl

AID

MS DEn

AIV

ICj

aca aca

rf

AcbC

3 2

AcbSh

VDB

IEn

Pir1 lo Tu1 2

Pig

3

VP

VP

ICj

azac

ICj OptF 2n PSph

HardG cav

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell AID agranular insular cx, dorsal AIV agranular insular cx, vent azac azygous ant cerebral art cav cavernous sinus cg cingulum Cg1 cingulate cortex, area 1 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx ec external capsule fmi forceps min corpus call GI granular insular cx HardG Harderian gland ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum IL infralimbic cortex lo lateral olfactory tract LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx MS medial septal nu ne neuroepithelium OptF optic foramen Pig pigment layer of the eye Pir1 piriform cx, layer 1 PrL prelimbic cx PSph presphenoid bone rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw S2 2ary somatosensory cx SHi septohippocampal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VDB nu vertical limb diagonal band VP ventral pallidum

Figure 115 P6 #12 2.79 mm

M2 M1

Cg1

S1FL cg

S1DZ

S1J

Cg2

ec IG cc

ne LV

DP

LSD

S2

SHi CPu

GI

LSI

DCl LSV DI VCl

MS

AID AIV

aca

DEn

aca

ICj

AcbC

rf IEn

3

VDB

2

VP

AcbSh

Pir1

CB lo

VP

ICj

ICj

3

ICj

2

acer

Tu1 OptF 2n PSph cav

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent cav cavernous sinus CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx DP dorsal peduncular cx ec external capsule GI granular insular cx ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum lo lateral olfactory tract LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx MS medial septal nu ne neuroepithelium OptF optic foramen Pir1 piriform cx, layer 1 PSph presphenoid bone rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw S2 2ary somatosensory cx SHi septohippocampal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VDB nu vertical limb diagonal band VP ventral pallidum

Figure 116 P6 #13 2.91 mm

M2 M1 Cg1 S1FL cg

S1DZ

Cg2 ec

IG

S1J

ne cc

LV

SHi

LSD ne S2

CPu LSI

GI DCl Fro

DI

LSV

VCl MS

AID aca

DEn

AIV

aca ICjM

AcbC

IEn 3

rf 2

LSS

Pir1 lo

2 Tu1

VP

AcbSh mfb

3

SIB VDB

CB

ICj VP

acer

ICj

PSphW 2n OptF

PSph

cav 5mx

EnO

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

NasC

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent cav cavernous sinus CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule EnO enamel organ Fro frontal bone GI granular insular cx ICj islands of Calleja ICjM islands of Calleja, major IEn intermed endopiriform nu IG indusium griseum lo lateral olfactory tract LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx mfb med forebrain bundle MS medial septal nu NasC nasal cavity ne neuroepithelium OptF optic foramen Pir1 piriform cx, layer 1 PSph presphenoid bone PSphW presphenoid wing rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1J prim somatosens, jaw S2 2ary somatosensory cx SHi septohippocampal nu SIB substantia innominata, basal Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VDB nu vertical limb diagonal band VP ventral pallidum

Figure 117 P6 #14 3.03 mm

M2

M1

Cg1 S1FL S1DZ cg

Cg2

S1J S1DZO

IG

ne cc LV

S1ULp

cc

ne LSD

S2

Ld

GI

CPu

DCl

LSI LSV

DI

VCl MS

AID AIV

DEn

aca

ICjM

rf AcbC

IEn

LSS

3 lo

2

SIB

AcbSh

VDB

LAcbSh

Pir1

ICj

Tu1

CB mfb VP ICj 3 2

HDB

acer

2n PSph

a

cav EnO

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

5mx

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 5mx 5n, maxillary division a artery aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent cav cavernous sinus CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx EnO enamel organ GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja ICjM islands of Calleja, major IEn intermed endopiriform nu IG indusium griseum LAcbSh lateral accumbens shell Ld lambdoid septal zone lo lateral olfactory tract LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx mfb med forebrain bundle MS medial septal nu ne neuroepithelium Pir1 piriform cx, layer 1 PSph presphenoid bone rf rhinal fissure S1DZ prim somatosens, dysgranul S1DZO prim somatosens, oral dysg S1FL prim somatosens, forelimb S1J prim somatosens, jaw S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SIB substantia innominata, basal Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VDB nu vertical limb diagonal band VP ventral pallidum

Figure 118 P6 #15 3.15 mm

M2 M1

Cg1

S1FL S1DZ cg

S1J

Cg2 IG

S1DZO ne

cc

LV S1ULp

LSD

ec

LSI

S2 GI

CPu

DCl

LSV

DI

MS VCl

AID AIV

aca

DEn rf

AcbSh

AcbC 3 2

IEn

VDB VP

LSS

Pir1 SIB

lo mfb 3 2 Tu1

ICj

HDB

VP ICj

acer 2n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

PSph

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum lo lateral olfactory tract LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx mfb med forebrain bundle MS medial septal nu ne neuroepithelium Pir1 piriform cx, layer 1 PSph presphenoid bone rf rhinal fissure S1DZ prim somatosens, dysgranul S1DZO prim somatosens, oral dysg S1FL prim somatosens, forelimb S1J prim somatosens, jaw S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SIB substantia innominata, basal Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VDB nu vertical limb diagonal band VP ventral pallidum

Figure 119 P6 #16 3.27 mm

M2 M1

Cg1

S1FL S1DZ

Cg2

cg S1J

IG ne

S1DZO

cc

LV LSD ec S1ULp

LSI

Ld

S2 GI

LSV

CPu

DCl

SHy

DI

STMA

VCl

AID rf

MS

AIV

aca DEn AcbC IEn

3

AcbSh

LSS

2

LPO VP

Pir1

SIB

CB

VOLT

lo

MCPO

ICj 3

HDB

ICj

2 Tu1

acer 2n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex aca anterior commissure, ant AcbC accumbens nu, core AcbSh accumbens nu, shell acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu DI dysgranular insular cx ec external capsule GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum Ld lambdoid septal zone lo lateral olfactory tract LPO lat preoptic area LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx MCPO magnocell preoptic nu MS medial septal nu ne neuroepithelium Pir1 piriform cx, layer 1 rf rhinal fissure S1DZ prim somatosens, dysgranul S1DZO prim somatosens, oral dysg S1FL prim somatosens, forelimb S1J prim somatosens, jaw S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SHy septohypothalamic nu SIB substantia innominata, basal STMA bed nu st, med div, ant Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VOLT vasc organ lam ter VP ventral pallidum

Figure 120 P6 #17 3.39 mm

M2

M1

Cg1

S1FL cg Cg2 S1DZ

IG ne

cc

LV LSD ne

S1ULp

df

ec SFi

fi

SHy

MS

LSI

S2

CPu

LSV

DCl

GI

STLD DI

STMA

VCl

STLP

AID AIV

aca

DEn

rf

IEn 3

LSS

LPO

IPAC VP

2

MnPO

Pir1 SIB

lo VP

MCPO

MPA VOLT

HDB

CB ICj 3 2 Tu1

acer 2n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex aca anterior commissure, ant acer anterior cerebral art AID agranular insular cx, dorsal AIV agranular insular cx, vent CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx ec external capsule fi fimbria hippocampus GI granular insular cx HDB nu horizlimb diagonal band ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx MCPO magnocell preoptic nu MnPO median preoptic nu MPA medial preoptic area MS medial septal nu ne neuroepithelium Pir1 piriform cx, layer 1 rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SHy septohypothalamic nu SIB substantia innominata, basal STLD bed nu st, lat div, dorsal STLP bed nu st, lat div, posterior STMA bed nu st, med div, ant Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VOLT vasc organ lam ter VP ventral pallidum

Figure 121 P6 #18 3.51 mm

M2 M1 S1HL

Cg1

S1FL S1DZ

cg

Cg2 IG

ne

S1ULp

cc

LV

LSD

ec

df

S2 LSI CPu

GI

TS

STLD LSV

DCl DI AID

SFi

fi

f

st

ic

SHy MnPO

STMAM

VCl

STLP STMAL

rf

ac

STLJ

AIV DEn

acp STI IEn

3 2 Pir1

LSS

STLV

Fu

IPAC

STMV SHy StA PS

VP SIB

Al

MnPO

MPA

3V

LPO

lo MCPO HDB Tu1 2

3

VOLT

ICj acer 4n

ASph ptgpal

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

3n

PSph

2n

6n cav

5oph 5mx

0

NasC

ptgcn

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 3n oculomotor nerve 3V 3rd ventricle 4n trochlear nerve 5mx 5n, maxillary division 5oph 5n, ophthalmic division 6n root of abducens nerve ac anterior commissure acer anterior cerebral art acp anterior comm, posterior AID agranular insular cx, dorsal AIV agranular insular cx, vent Al alar nu ASph alisphenoid bone cav cavernous sinus cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx ec external capsule f fornix fi fimbria hippocampus Fu bed nu st, fusiform GI granular insular cx HDB nu horizlimb diagonal band ic internal capsule ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LSV lat septal nu, vent part LV lateral ventricle M1 primary motor cx M2 secondary motor cx MCPO magnocell preoptic nu MnPO median preoptic nu MPA medial preoptic area NasC nasal cavity ne neuroepithelium Pir1 piriform cx, layer 1 PS parastrial nu PSph presphenoid bone ptgcn nerve of the pterygoid canal ptgpal pterygopalatine n rf rhinal fissure S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SHy septohypothalamic nu SIB substantia innominata, basal st stria terminalis StA strial part preoptic area STI ST, intermediate div STLD bed nu st, lat div, dorsal STLJ bed nu st, lat div, juxtacap STLP bed nu st, lat div, posterior STLV bed nu st, lat div, ventral STMAL bed nu st, med div, ant lat STMAM bed nu st, med div, ant med STMV bed nu st, med div, ventral TS triangular septal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum VOLT vasc organ lam ter VP ventral pallidum

Figure 122 P6 #19 3.63 mm

M2

M1 S1HL

Cg1 S1FL S1DZ

cg

Cg2 IG

S1ULp

cc

ne

ne

LV

LSD LSI

ec

df

fi S2

SFi

TS vhc

GI

DI

STD

CPu

LTer

st

ic

SHy f

DCl STMAM

AIP

STMAL STLI STLP

VCl

BAC

ac

IPAC

DEn

STLV LSS IEn

3 2 Pir1

MnPO

STI

STLJ

acp

IPAC

STMV Fu PS

Pe

MPOL

VP SIB

CB

SHy

StA

LPO MPA

MCPO lo

3V

HDB

VLPO

3 Tu1

2

VOLT VMPO

acer 2n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 3V 3rd ventricle ac anterior commissure acer anterior cerebral art acp anterior comm, posterior AIP agranular insular cx, post BAC bed nu ant commissure CB cell bridges vent striatum cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx ec external capsule f fornix fi fimbria hippocampus Fu bed nu st, fusiform GI granular insular cx HDB nu horizlimb diagonal band ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LSD lat septal nu, dorsal part LSI lat septal nu, intermed LSS lat stripe striatum LTer lemina terminalis LV lateral ventricle M1 primary motor cx M2 secondary motor cx MCPO magnocell preoptic nu MnPO median preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral ne neuroepithelium Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PS parastrial nu S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SHy septohypothalamic nu SIB substantia innominata, basal st stria terminalis StA strial part preoptic area STD bed nu st, dorsal part STI ST, intermediate div STLI bed nu st, lat div, intermed STLJ bed nu st, lat div, juxtacap STLP bed nu st, lat div, posterior STLV bed nu st, lat div, ventral STMAL bed nu st, med div, ant lat STMAM bed nu st, med div, ant med STMV bed nu st, med div, ventral TS triangular septal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VOLT vasc organ lam ter VP ventral pallidum

Figure 123 P6 #20 3.75 mm

M2

M1 S1HL

Cg1

S1FL cg

Cg2

S1DZ

IG S1BF

ne

cc ne LV

S1ULp

LSD

ne

ec

df

TS

SFi fi

S2

vhc SFO

IVF AV

GI DI

st

CPu

PVA

STMPM

ic

DCl

PT

STMP

f

GP

VCl

LTer

AIP

STMPI BAC STMPL

DEn

IPAC acp

LSS IEn

3

STLP

IPAC

STLV

STLI

ac SHy

StHy PDPO

Pe

VP

2

LPO

SIB

Pir1

MPOL MPA

MCPO lo

3 Tu1 2

AVPe

HDB VLPO

mcer

2n

acer

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

3V

0.4

0.6

VMPO

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 3V 3rd ventricle ac anterior commissure acer anterior cerebral art acp anterior comm, posterior AIP agranular insular cx, post AV anteroventral thalamic nu AVPe ant ventral periventric nu BAC bed nu ant commissure cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx ec external capsule f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac IVF interventricular foramen lo lateral olfactory tract LPO lat preoptic area LSD lat septal nu, dorsal part LSS lat stripe striatum LTer lemina terminalis LV lateral ventricle M1 primary motor cx M2 secondary motor cx mcer middle cerebral artery MCPO magnocell preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral ne neuroepithelium PDPO posterodorsal preoptic nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PT paratenial thalamic nu PVA paraventricular thal nu, ant S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SFO subfornical organ SHy septohypothalamic nu SIB substantia innominata, basal st stria terminalis StHy striohypothalamic nu STLI bed nu st, lat div, intermed STLP bed nu st, lat div, posterior STLV bed nu st, lat div, ventral STMP bed nu st, med div, post STMPI bed nu st, med div, postint STMPL bed nu st, med div, post lat STMPM bed nu st, med div, post med TS triangular septal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum

Figure 124 P6 #21 3.87 mm

M2

M1

Cg1

S1HL S1FL S1DZ

cg

Cg2

dcw

S1BF

IG cc

ne LV ne

df

LSD

TS

ec

SFi

S1ULp

vhc

fi S2 RtSt GI

DI

DCl

Rt

ic

PT

PVA

GP

VCl

LSS

PL

DEn

STM

STLP

B

PM STM PI STM

AIP

CPu

sm

AV

st

SFO

AD

f

EAC

acp

PaAP

ns

IPAC

StHy

VP

IEn

Pe

3V

PDPO

3 Pir1

Re

SIB

2

LPO

MPOC

MPA MPOL

MCPO

MPOM HDB

lo Tu1

2

mcer

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

3

AA VLPO acer

ICj

0

0.2

3V

2n VMPO

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 2n optic nerve 3 layer 3 of cortex 3V 3rd ventricle AA anterior amyg area acer anterior cerebral art acp anterior comm, posterior AD anterodorsal thalamic nu AIP agranular insular cx, post AV anteroventral thalamic nu B basal nu (Meynert) cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CPu caudate putamen (striatum) DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx EAC sublent extend amyg, cent ec external capsule f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band ic internal capsule ICj islands of Calleja IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LSD lat septal nu, dorsal part LSS lat stripe striatum LV lateral ventricle M1 primary motor cx M2 secondary motor cx mcer middle cerebral artery MCPO magnocell preoptic nu MPA medial preoptic area MPOC medial preoptic nu, central MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial ne neuroepithelium ns nigrostriatal bundle PaAP paraventric hy, ant parvicell PDPO posterodorsal preoptic nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PT paratenial thalamic nu PVA paraventricular thal nu, ant Re reuniens thalamic nu Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SFO subfornical organ SIB substantia innominata, basal sm stria medullaris thal st stria terminalis StHy striohypothalamic nu STLP bed nu st, lat div, posterior STMPI bed nu st, med div, postint STMPL bed nu st, med div, post lat STMPM bed nu st, med div, post med TS triangular septal nu Tu1 olfactory tubercle, layer 1 VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum

Figure 125 P6 #22 3.99 mm

M2

M1

Cg1

S1HL S1FL S1DZ

cg

Cg2

dcw

IG

S1BF ne

cc

ne

SFi

LV S1ULp

ec

S2

vhc SFO AD

sm

AV

st

PVA

PT

CPu AM

ic Rt

DCl DI

GP

CM sm

AIP

TS

fi

RtSt

GI

df

VCl

VRe

B

Re f

rf

STMP

DEn

3 Pir1

2

LSS LSS

PaAP

EAC

acp

StHy

IPAC

VP

IEn

SIB

LPO

3V

MPA

Pe MPOL

HDB

MPOM

MCPO lo

ACo

AA

VMPO och

VLPO

Tu

acer

mcer

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2 layer 2 of cortex 3 layer 3 of cortex 3V 3rd ventricle AA anterior amyg area acer anterior cerebral art ACo ant cortical amygdaloid nu acp anterior comm, posterior AD anterodorsal thalamic nu AIP agranular insular cx, post AM anteromedial thalamic nu AV anteroventral thalamic nu B basal nu (Meynert) cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CM central medial thal nu CPu caudate putamen (striatum) DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu df dorsal fornix DI dysgranular insular cx EAC sublent extend amyg, cent ec external capsule f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus HDB nu horizlimb diagonal band ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac lo lateral olfactory tract LPO lat preoptic area LSS lat stripe striatum LV lateral ventricle M1 primary motor cx M2 secondary motor cx mcer middle cerebral artery MCPO magnocell preoptic nu MPA medial preoptic area MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial ne neuroepithelium och optic chiasm PaAP paraventric hy, ant parvicell Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PT paratenial thalamic nu PVA paraventricular thal nu, ant Re reuniens thalamic nu rf rhinal fissure Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SFi septofimbrial nu SFO subfornical organ SIB substantia innominata, basal sm stria medullaris thal st stria terminalis StHy striohypothalamic nu STMP bed nu st, med div, post TS triangular septal nu Tu olfactory tubercle VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum VRe vent reuniens thalamic nu

Figure 126 P6 #23 4.11 mm

M2

M1

Cg1

S1HL S1FL S1DZ

cg

Cg2

dcw S1BF

IG Py

ne CA3

ne

Rad

ec

AD

LDVL

RtSt

st

PT IAD

eml

DCl ic

GP

VCl AIP

sm

DEn

LSS

Xi f

SM

rf IEn

EAC LPO

ACo

Pe

MPA HDB

3

3V MPOM

MCPO

2 CxA1

PaAP

StHy SIB

VP

PaXi

STMP

IPAC

Pir1 2 3

Re

VRe B

acp

CM

AM

Rt

DI

PVA

MD

AVDM

CPu

MHb

sm

AVVL GI

SFO D3V

LDDM

fi

S2

GrDG vhc MoDG

SLu

LV S1ULp

cc

MPOL

AA

VMPO

VLPO acer

SCh och

mcer

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle AA anterior amyg area acer anterior cerebral art ACo ant cortical amygdaloid nu acp anterior comm, posterior AD anterodorsal thalamic nu AIP agranular insular cx, post AM anteromedial thalamic nu AVDM ant vent thal nu, dorsomed AVVL ant ventral thal, ventrolat B basal nu (Meynert) CA3 field CA3 hippocampus cc corpus callosum cg cingulum Cg1 cingulate cortex, area 1 Cg2 cingulate cortex, area 2 CM central medial thal nu CPu caudate putamen (striatum) CxA1 cortex-amyg trans, lr 1 D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu DI dysgranular insular cx EAC sublent extend amyg, cent ec external capsule eml external medullary lamina f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus HDB nu horizlimb diagonal band IAD interanterodorsal thal nu ic internal capsule IEn intermed endopiriform nu IG indusium griseum IPAC interst nu post limb ac LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LPO lat preoptic area LSS lat stripe striatum LV lateral ventricle M1 primary motor cx M2 secondary motor cx mcer middle cerebral artery MCPO magnocell preoptic nu MD mediodorsal thalamic nu MHb med habenular nu MoDG molecular dentate gyrus MPA medial preoptic area MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial ne neuroepithelium och optic chiasm PaAP paraventric hy, ant parvicell PaXi paraxiphoid nu of thalamus Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PT paratenial thalamic nu PVA paraventricular thal nu, ant Py pyramidal cell hippocampus Rad radiatum layer hippocamp Re reuniens thalamic nu rf rhinal fissure Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1FL prim somatosens, forelimb S1HL prim somatosens, hindlimb S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SCh suprachiasmatic nu SFO subfornical organ SIB substantia innominata, basal SLu stratum lucidum hippocamp SM nu stria medullaris sm stria medullaris thal st stria terminalis StHy striohypothalamic nu STMP bed nu st, med div, post VCl vent part claustrum vhc ventral hippocamp comm VLPO ventlat preoptic nu VMPO ventmed preoptic nu VP ventral pallidum VRe vent reuniens thalamic nu Xi xiphoid thal nu

Figure 127 P6 #24 4.23 mm

M2

M1

RSD

S1HL RSGc

S1Sh cg

S1DZ

alv IG

dcw

Or

S1BF

Py

GrDG dhc

Rad

SLu

CA3 ne

ic

ec

cc

LV

S1ULp

fi LDDM LDVL

RtSt

sm LHb

AD

MD

PC

S2

st

AVDM

PVA

mt

CL

CM

IAD

CPu

DI

AM

Rt

ic

DCl

Rh

GP

AMV

VCl

Re

VRe

Xi

AIP ZIR

B DEn rf

LSS

D3V

PT

AVVL GI

MoDG MHb

sm

acp

SM

EAC

IPAC

ANS f

BCo

PaMM PaXi PaMP PaV SPa

STMP

VP SIB 3 Pir1 2

VEn

PLH

MCPO

3V

AHA AA

3 ACo

MPOM

HDB

Pe VLH ESO

2 LOT1

acer

0

LA

SCh och SChVM

SO

mcer

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MPOL

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle AA anterior amyg area acer anterior cerebral art ACo ant cortical amygdaloid nu acp anterior comm, posterior AD anterodorsal thalamic nu AHA anterior hypothal area, ant AIP agranular insular cx, post alv alveus hippocampus AM anteromedial thalamic nu AMV anteromed thal nu, vent ANS access neurosecretory nu AVDM ant vent thal nu, dorsomed AVVL ant ventral thal, ventrolat B basal nu (Meynert) BCo basal nu, core cc corpus callosum cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DI dysgranular insular cx EAC sublent extend amyg, cent ec external capsule ESO episupraoptic nu f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus HDB nu horizlimb diagonal band IAD interanterodorsal thal nu ic internal capsule IG indusium griseum IPAC interst nu post limb ac LA lateroanterior hypothal nu LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LHb lateral habenular nu LOT1 nu lat olf tract, layer 1 LSS lat stripe striatum LV lateral ventricle M1 primary motor cx M2 secondary motor cx mcer middle cerebral artery MCPO magnocell preoptic nu MD mediodorsal thalamic nu MHb med habenular nu MoDG molecular dentate gyrus MPOL medial preoptic nu, lateral MPOM medial preoptic nu, medial mt mammillothalamic tract ne neuroepithelium och optic chiasm Or oriens layer hippocampus PaMM paravent hy, med magnocel PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy PT paratenial thalamic nu PVA paraventricular thal nu, ant Py pyramidal cell hippocampus Rad radiatum layer hippocamp Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1HL prim somatosens, hindlimb S1Sh prim somatosens, shoulder S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SCh suprachiasmatic nu SChVM suprachiasmatic, ventromed SIB substantia innominata, basal SLu stratum lucidum hippocamp SM nu stria medullaris sm stria medullaris thal SO supraoptic nu Refer to Index of Abbreviations for other entries

Figure 128 P6 #25 4.35 mm

M2

M1

RSD

S1HL S1Sh S1DZ

S1BF

CA3 ne

Py

ne

LV

PoDG GrDG fi

MHb

LHb CL

st

AVDM PT

PC

VL

CM

AVVL

mt

CPu

IAM

AM

DCl

Rt

Rh

VA AMV

VCl

GP

AIP

ic

B

Re Xi

B VRe

ZIR

DEn BLA

rf 3 2 Pir1

PVA

MD

S2

DI

D3V

sm

LDDM

LDVL

RtSt

GI

dhc

MoDG

ec

S1ULp

cc

Rad

hif

SLu

IG

Or

CA2 CA1 LMol

dcw

RSGc

cg

alv

EAC

LSS I

ANS

SM

EAM

PaXi PaLM

f

SPa

CeM

3V

VEn

MCPO

AA BMA

PLH

PaV AHA

HDB

cst

SChDL

3 3 2 CxA1

ACo

VLH

2 LOT1

BAOT

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

PaMP

PaV

Pe

LA

ESO MeAD acer mcer

SChVM sox

SO

0

0.2

opt

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle AA anterior amyg area acer anterior cerebral art ACo ant cortical amygdaloid nu AHA anterior hypothal area, ant AIP agranular insular cx, post alv alveus hippocampus AM anteromedial thalamic nu AMV anteromed thal nu, vent ANS access neurosecretory nu AVDM ant vent thal nu, dorsomed AVVL ant ventral thal, ventrolat B basal nu (Meynert) BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BMA basomed amyg nu, ant cc corpus callosum CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) cst comm stria terminalis CxA1 cortex-amyg trans, lr 1 D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DI dysgranular insular cx EAC sublent extend amyg, cent EAM sublent extended amyg, med ec external capsule ESO episupraoptic nu f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus HDB nu horizlimb diagonal band hif hippocampal fissure I intercalated nuclei amyg IAM interanteromedthal nu ic internal capsule IG indusium griseum LA lateroanterior hypothal nu LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LHb lateral habenular nu LMol lacunosum moleculare LOT1 nu lat olf tract, layer 1 LSS lat stripe striatum LV lateral ventricle M1 primary motor cx M2 secondary motor cx mcer middle cerebral artery MCPO magnocell preoptic nu MD mediodorsal thalamic nu MeAD med amygd nu, ant dors MHb med habenular nu MoDG molecular dentate gyrus mt mammillothalamic tract ne neuroepithelium opt optic tract Or oriens layer hippocampus PaLM paravent hy, lat magnocell PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy PoDG polymorph dentate gyrus PT paratenial thalamic nu PVA paraventricular thal nu, ant Py pyramidal cell hippocampus Rad radiatum layer hippocamp Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1HL prim somatosens, hindlimb S1Sh prim somatosens, shoulder S1ULp prim somatosens, upper lip S2 2ary somatosensory cx SChDL suprachiasmatic, dorsolat Refer to Index of Abbreviations for other entries

Figure 129 P6 #26 4.47 mm

MPtA

LPtA

S1Tr

RSD

S1Sh S1DZ alv CA2

dcw

Py MoDG Rad LMol

hif CA3

dhc D3V

PoDG GrDG

S1ULp fi

ec

LDDM AVDM

LDVL

S2

AVVL

RtSt

st

VL CPu Rt

MHb LHbM

sm CL

PVA LHbL MD IMD AngT PT PC CM AM

LV

DCl

cc

SLu

ne

GI

IG

Or

CA1

S1BF

RSGc

cg

Sub

VCl

DI

Rh

mt

GP

VM

B AIP

IAM

AMV

VA

B

DEn

ic

VRe

Re

ZIR CeL

BLA

CeM

rf Pir1

2

3

EAC

CeC

ANS JPLH

SM

EAM

MCPO AA HDB

PLH AHA

ACo

LA

SChDL

SO

MeAD

3V PaV A14 Pe

ESO

LOT

BAOT

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

SPa

VLH

BMA

2 CxA1

PaMP AHC

cst 3

PaLM

f

I VEn

Xi

PaXi

sm

opt

ictd

0

0.2

0.4

SChVM

0.6

sox

0.8

1.0 mm

3V 3rd ventricle A14 A14 dopamine cells AA anterior amyg area ACo ant cortical amygdaloid nu AHA anterior hypothal area, ant AHC anterior hy area, central AIP agranular insular cx, post alv alveus hippocampus AM anteromedial thalamic nu AMV anteromed thal nu, vent AngT angular thalamic nu ANS access neurosecretory nu AVDM ant vent thal nu, dorsomed AVVL ant ventral thal, ventrolat B basal nu (Meynert) BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BMA basomed amyg nu, ant cc corpus callosum CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) cst comm stria terminalis CxA1 cortex-amyg trans, lr 1 D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DI dysgranular insular cx EAC sublent extend amyg, cent EAM sublent extended amyg, med ec external capsule ESO episupraoptic nu f fornix fi fimbria hippocampus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus HDB nu horizlimb diagonal band hif hippocampal fissure I intercalated nuclei amyg IAM interanteromedthal nu ic internal capsule ictd internal carotid artery IG indusium griseum IMD intermediodorsal thal nu JPLH juxtaparaventricular lat hy LA lateroanterior hypothal nu LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LOT nu lateral olfactory tract LPtA lat parietal association cx LV lateral ventricle MCPO magnocell preoptic nu MD mediodorsal thalamic nu MeAD med amygd nu, ant dors MHb med habenular nu MoDG molecular dentate gyrus MPtA med parietal association cx mt mammillothalamic tract ne neuroepithelium opt optic tract Or oriens layer hippocampus PaLM paravent hy, lat magnocell PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy PoDG polymorph dentate gyrus PT paratenial thalamic nu PVA paraventricular thal nu, ant Py pyramidal cell hippocampus Rad radiatum layer hippocamp Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel Refer to Index of Abbreviations for other entries

Figure 130 P6 #27 4.59 mm

RSD

MPtA

LPtA S1DZ

S1BF

RSGc

cg

alv

Or IG

Py

CA1

Rad

CA2

MoDG

LV

cc

LMol

dhc

FC dcw

SLu

S1ULp

LDDM

LDVL fi

ec LV

RtSt

LHbM

LHbL

AngT

MDM IMD

PC

CM

VPL

CPu

VA

DI VCl

AM

IAM

Rt

GP

Rh

ic scp

LaDL

DEn

PV

MDL

st

GI

AIP

MHb

CL

VL DCl

D3V

sm ne

ne S2

hif

PoDG GrDG

CA3

mt

VM

Re

VRe

CeL ZIR BLA

EP

CeM

CeC

ANS JPLH

EAC Pir1 2

EAM

3 VEn

cst

IM

AA BMA

MCPO MeAD MeAV

f

HDB

CxA1

PaMP PaV

VLH SPa

ESO LA

SChDL

TuLH

opt

SChVM

BAOT

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

PaLM AHP

AHC

SO ictd

ACo

Xi

PLH

3 2

PaXi PaDC

sox

0

0.2

0.4

0.6

0.8

1.0 mm

3V Pe

3V 3rd ventricle AA anterior amyg area ACo ant cortical amygdaloid nu AHC anterior hy area, central AHP ant hypothal area, post AIP agranular insular cx, post alv alveus hippocampus AM anteromedial thalamic nu AngT angular thalamic nu ANS access neurosecretory nu BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BMA basomed amyg nu, ant cc corpus callosum CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div CL centrolateral thalamic nu cg cingulum CM central medial thal nu CPu caudate putamen (striatum) cst comm stria terminalis CxA1 cortex-amyg trans, lr 1 D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DI dysgranular insular cx EAC sublent extend amyg, cent EAM sublent extended amyg, med ec external capsule EP entopeduncular nu ESO episupraoptic nu f fornix FC fasciola cinereum fi fimbria hippocampus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus HDB nu horizlimb diagonal band hif hippocampal fissure IAM interanteromedthal nu ic internal capsule ictd internal carotid artery IG indusium griseum IM intercalated amygd nu, main IMD intermediodorsal thal nu JPLH juxtaparaventricular lat hy LA lateroanterior hypothal nu LaDL lat amyg nu, dorsolat LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPtA lat parietal association cx LV lateral ventricle MCPO magnocell preoptic nu MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent MHb med habenular nu MoDG molecular dentate gyrus MPtA med parietal association cx mt mammillothalamic tract ne neuroepithelium opt optic tract Or oriens layer hippocampus PaDC paraventric hy dorsal cap PaLM paravent hy, lat magnocell PaMP paravent hy, med parvicell PaV paraventric hy nu, vent PaXi paraxiphoid nu of thalamus PC paracentral thalamic nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy PoDG polymorph dentate gyrus PV paraventricular thalamic nu Py pyramidal cell hippocampus Rad radiatum layer hippocamp Re reuniens thalamic nu Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu RtSt reticluostrial nu S1BF prim somatosens, barrel S1DZ prim somatosens, dysgranul S1ULp prim somatosens, upper lip Refer to Index of Abbreviations for other entries

Figure 131 P6 #28 4.71 mm

RSD

MPtA

LPtA

RSGc S1BF

cg

alv Or CA1 CA2

S2

cc

LMol MoDG

GrDG

CA3 DLG fi

AuV

CL

VG

MDM

VL VPM

Rt

CM

VPL

VCl GP

AM Sub

ic VM

LaDL DEn

rf

IMD

PC

CPu

AIP

PV

MDC

AngT

st

DI

LHbL

MDL

LV

DCl

D3V

LHbM

LDDM

LDVL

ne

sm MHb

ne ec

chp

PoDG

SLu

Au1

dhc

FC

hif

dcw

AuD

GI

IG

Py

Rad

IMG CeC

mt Re

EP

CeL

BLA

Rh

VRe ZIR

CeM EA

PaXi PaMP

PaPo

cst

3

Xi

PaDC

2 Pir1

IM AA

I

PLH

MeAD

3V

AHP

f AHC

CxA

BLV

BMA

MeAV

PTe VMHSh

SO ACo BAOT

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Pe

TuLH

opt

SPa

VMH

sox

ictd

RChL

0

0.2

0.4

0.6

RCh

0.8

1.0 mm

3V 3rd ventricle AA anterior amyg area ACo ant cortical amygdaloid nu AHC anterior hy area, central AHP ant hypothal area, post AIP agranular insular cx, post alv alveus hippocampus AM anteromedial thalamic nu AngT angular thalamic nu Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BLV basolat amyg, ventral BMA basomed amyg nu, ant cc corpus callosum CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum chp choroid plexus CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) cst comm stria terminalis CxA cortex-amyg transition D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DI dysgranular insular cx DLG dorsal lat geniculate nu EA sublenticular extend amyg ec external capsule EP entopeduncular nu f fornix FC fasciola cinereum fi fimbria hippocampus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus hif hippocampal fissure I intercalated nuclei amyg ic internal capsule ictd internal carotid artery IG indusium griseum IM intercalated amygd nu, main IMD intermediodorsal thal nu IMG amyg intramedullary gr LaDL lat amyg nu, dorsolat LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPtA lat parietal association cx LV lateral ventricle MDC MD thal nu, central MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent MHb med habenular nu MoDG molecular dentate gyrus MPtA med parietal association cx mt mammillothalamic tract ne neuroepithelium opt optic tract Or oriens layer hippocampus PaDC paraventric hy dorsal cap PaMP paravent hy, med parvicell PaPo paraventricular hy nu, post PaXi paraxiphoid nu of thalamus PC paracentral thal nu Pe periventricular hypothal nu Pir1 piriform cx, layer 1 PLH peduncular part lat hy PoDG polymorph dentate gyrus PTe paraterete nu PV paraventricular thalamic nu Py pyramidal cell hippocampus Rad radiatum layer hippocamp RCh retrochiasmatic area RChL retrochiasmatic, lateral Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGc retrosplenial granular cx, c Rt reticular thal nu Refer to Index of Abbreviations for other entries

Figure 132 P6 #29 4.83 mm

PtPD

RSD

V2MM

V2ML

RSGc

PtPR cg S1BF

RSGb IG

Or Py Rad

CA1

cc

LMol S2 dcw CA2 AuD

PoDG

D3V sm MHb

IMA LDVL

DLG

Au1

LHbM

LDDM

LHbM fr MDC

IGL

AuV

LV GI

MDL

PV

MDM IMD

eml st

VPM Rt

CPu

DCl

CL

Po

ne

ne

ec

AngT

VG

fi

DI

hif GrDG

SLu CA3

dhc

FC

MoDG

VL

VPL

CM

VCl

AIP DEn

LaDL

GP

IMG

CeC

mt CeM

ZIR MCLH

BLA

2

Re

EP

3 Pir1

Rh

Sub

VM

ml

CeL

rf VEn

ic

A13

ns

Stg

mfb

STIA MeAD

VRe Xi PaXi

AHP

PLH

3V

f

BLV BMA

PTe

Pe

PeFLH

MeAV VMHSh

opt

ACo

VMH

TuLH

sox BAOT ictd

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

RChL

0.2

0.4

0.6

0.8

Arc

1.0 mm

3V 3rd ventricle A13 A13 dopamine cells ACo ant cortical amygdaloid nu AHP ant hypothal area, post AIP agranular insular cx, post AngT angular thalamic nu Arc arcuate hypothal nu Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BAOT bed nu access olfactory tr BLA basolat amyg nu, ant BLV basolat amyg, ventral BMA basomed amyg nu, ant cc corpus callosum CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) D3V dorsal 3rd ventricle DCl dors part of claustrum dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DI dysgranular insular cx DLG dorsal lat geniculate nu ec external capsule eml external medullary lamina EP entopeduncular nu f fornix FC fasciola cinereum fi fimbria hippocampus fr fasciculus retroflexus GI granular insular cx GP globus pallidus GrDG granular dentate gyrus hif hippocampal fissure ic internal capsule ictd internal carotid artery IG indusium griseum IGL intergeniculate leaf IMA intramedullary thalamic area IMD intermediodorsal thal nu IMG amyg intramedullary gr LaDL lat amyg nu, dorsolat LDDM laterodor th nu, dorsomed LDVL laterodor thal nu, ventrolat LHbM lateral habenular nu, medial LMol lacunosum moleculare LV lateral ventricle MCLH magnocell nu lat hypothal MDC MD thal nu, central MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MeAV med amygd nu, anterovent mfb med forebrain bundle MHb med habenular nu ml medial lemniscus MoDG molecular dentate gyrus mt mammillothalamic tract ne neuroepithelium ns nigrostriatal bundle opt optic tract Or oriens layer hippocampus PaXi paraxiphoid nu of thalamus Pe periventricular hypothal nu PeFLH perifornical part of lat hy Pir1 piriform cx, layer 1 PLH peduncular part lat hy Po post thal nuclear group PoDG polymorph dentate gyrus PTe paraterete nu PtPD parietal cx, post, dorsal PtPR parietal cx, post, rostral PV paraventricular thalamic nu Py pyramidal cell hippocampus Rad radiatum layer hippocamp RChL retrochiasmatic, lateral Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c Rt reticular thal nu S1BF prim somatosens, barrel S2 2ary somatosensory cx SLu stratum lucidum hippocamp Refer to Index of Abbreviations for other entries

Figure 133 P6 #30 4.95 mm

RSD

V2MM V2ML

RSGc

V1 alv

V2L

Py Rad

PtPR

cg

IG cc

CA1

LMol MoDG

S1

D3V GrDG

AuD

hif sm

SLu

Au1

LPMR

LDVL

DLG IGL

CA3

MHb

LHbL

LHbM

CL VG

AuV

Po iml

DEn

rf

IMG

LaVL

ic

CeL

LaVM

3 2 Pir1

VM

Sub Re

EP

mt

ZIR

BLA

ns

BLP

I

STIA

A13

MePD

mfb MCLH

BLV

MeAD BMP 3 2 PLCo1

BMA

opt MePV

ACo

CM Rh

ml

cst CeM

CeC

PC

VPL

st LaDL

MDL

Rt

Ect PRh

IMD

MDM

VPM

LV

CPu

PVP

MDC eml

TeA

fr

AngT

fi

ec

dhc

FC

PoDG

CA2

LEnt

RSGb

Or

PTe

VRe PaXi Xi DA

PeFLH PeF f VMHC

DMD

3V VMHDM

VMHSh

PMCo

VMHVL sox

MTu

Arc RChL

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A13 A13 dopamine cells ACo ant cortical amygdaloid nu alv alveus hippocampus AngT angular thalamic nu Arc arcuate hypothal nu Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLA basolat amyg nu, ant BLP basolat amyg nu, post BLV basolat amyg, ventral BMA basomed amyg nu, ant BMP basomed amyg nu, post cc corpus callosum CeC central amyg nu, capsular CeL central amygd nu, lat div CeM central amyg nu, med div cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) cst comm stria terminalis D3V dorsal 3rd ventricle DA dorsal hypothal area DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLG dorsal lat geniculate nu DMD dorsomed hypothal nu,dorsal ec external capsule Ect ectorhinal cortex eml external medullary lamina EP entopeduncular nu f fornix FC fasciola cinereum fi fimbria hippocampus fr fasciculus retroflexus GrDG granular dentate gyrus hif hippocampal fissure I intercalated nuclei amyg ic internal capsule IG indusium griseum IGL intergeniculate leaf IMD intermediodorsal thal nu IMG amyg intramedullary gr iml int medullary lamina LaDL lat amyg nu, dorsolat LaVL lat amyg nu, ventrolat LaVM lat amyg nu, ventromed LDVL laterodor thal nu, ventrolat LEnt lateral entorhinal cx LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPMR LP thal nu, mediorostral LV lateral ventricle MCLH magnocell nu lat hypothal MDC MD thal nu, central MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MeAD med amygd nu, ant dors MePD med amygd nu, posterodors MePV med amyg nu, posterovent mfb med forebrain bundle MHb med habenular nu ml medial lemniscus MoDG molecular dentate gyrus mt mammillothalamic tract MTu medial tuberal nu ns nigrostriatal bundle opt optic tract Or oriens layer hippocampus PaXi paraxiphoid nu of thalamus PC paracentral thal nu PeF perifornical nu PeFLH perifornical part of lat hy Pir1 piriform cx, layer 1 PLCo1 posterolat cortical amyg, 1 PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus PRh perirhinal cx PTe paraterete nu PtPR parietal cx, post, rostral PVP paraventricular thal nu, post Py pyramidal cell hippocampus Rad radiatum layer hippocamp RChL retrochiasmatic, lateral Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx Refer to Index of Abbreviations for other entries

Figure 134 P6 #31 5.07 mm

RSD

V2MM

V2ML V1

RSGc

V2L alv

PtPD PtPR

cg RSGb

Or Py Rad

CA1

IG cc

LMol

S1

MoDG

ec

PoDG

hif

sm D3V

GrDG

AuD

MHb

CA2 IMA Au1

LHbL

LPMR

LPLR

LHbM

DLG

SLu

IGL

AuV

fr

CL

eml

CA3

Po

PRh rf

Rt

VPL

LV

CM

ml

LaDL

LEnt

st

LaVM CeC LaVL

SubG

Rh VM

DEn

Pir1 2

IMD

iml

fi ne CPu

MDM

PC

VPM

Ect

PVP

MDL

VG TeA

dhc

FC

Re

ZID IMG

Sub

ic EP

STIA

mt VRe

ZIV A13

3

BLP

BLA I

MePD

PHD

DA

SubI MCLH

DMD

sox BLV

BMP

MePV

PeF f VMHSh

PTe opt

3V

VMHC

PeFLH

PMCo

Pe

VMHDM

PLCo

VMHVL

MTu ictd

ArcD ArcL ArcM ME

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A13 A13 dopamine cells alv alveus hippocampus ArcD arcuate hypothal nu, dors ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLA basolat amyg nu, ant BLP basolat amyg nu, post BLV basolat amyg, ventral BMP basomed amyg nu, post cc corpus callosum CeC central amyg nu, capsular cg cingulum CL centrolateral thal nu CM central medial thal nu CPu caudate putamen (striatum) D3V dorsal 3rd ventricle DA dorsal hypothal area DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLG dorsal lat geniculate nu DMD dorsomed hypothal nu,dorsal ec external capsule Ect ectorhinal cortex eml external medullary lamina EP entopeduncular nu f fornix FC fasciola cinereum fi fimbria hippocampus fr fasciculus retroflexus GrDG granular dentate gyrus hif hippocampal fissure I intercalated nuclei amyg ic internal capsule ictd internal carotid artery IG indusium griseum IGL intergeniculate leaf IMA intramedullary thalamic area IMD intermediodorsal thal nu IMG amyg intramedullary gr iml int medullary lamina LaDL lat amyg nu, dorsolat LaVL lat amyg nu, ventrolat LaVM lat amyg nu, ventromed LEnt lateral entorhinal cx LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LV lateral ventricle MCLH magnocell nu lat hypothal MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med ME median eminence MePD med amygd nu, posterodors MePV med amyg nu, posterovent MHb medial habenular nu ml medial lemniscus MoDG molecular dentate gyrus mt mammillothalamic tract MTu medial tuberal nu ne neuroepithelium opt optic tract Or oriens layer hippocampus PC paracentral thal nu Pe periventricular hypothal nu PeF perifornical nu PeFLH perifornical part of lat hy PHD post hypothal area, dorsal Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus PRh perirhinal cx PTe paraterete nu PtPD parietal cx, post, dorsal PtPR parietal cx, post, rostral PVP paraventricular thal nu, post Py pyramidal cell hippocampus Rad radiatum layer hippocamp Re reuniens thalamic nu rf rhinal fissure Rh rhomboid thal nu RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c Rt reticular thal nu Refer to Index of Abbreviations for other entries

Figure 135 P6 #32 5.19 mm

RSD

V2MM

V2ML V1

RSGc

V2L alv

LV

PtPD

cg RSGb IG

Or

PtPR

Py AuD

Rad

dcw AuV

CA2

D3V

LPLR

IMA

DS

hif

PoDG GrDG

Au1

scc dhc FC

MoDG

LMol

MHb

LPMR

LHbL LHbM

CL

DLG str IGL

SLu

TeA Ect

VG1 2

CA3

Po

MDL MDM

eml

3

VPM VPL

DEn

ne

LaDL

VPPC

SubG

LV ne

RRe

ZID ZIV

st

LaVM Pir1 2 3

CM

fi

LEnt

ic

VM PHD

STh

mt

A11

STIA

BLP

I

MePD MCLH

BMP sox

BLV

PTe AHiAL

RAPir

IMD

OPC

PRh rf

PVP

fr

PMCo

PeFLH

DMD

PeF

DMC

opt

f Te

PLCo

Pe

DMV VMHC VMHDM

MTu

3V

VMHVL ArcD

VMHSh

ictd

ArcL

ArcM MEI MEE

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A11 A11 dopamine cells AHiAL amygdalohip area, antlat alv alveus hippocampus ArcD arcuate hypothal nu, dors ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post BLV basolat amyg, ventral BMP basomed amyg nu, post cg cingulum CL centrolateral thal nu CM central medial thal nu D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLG dorsal lat geniculate nu DMC dorsomed hy nu, compact DMD dorsomed hypothal nu,dorsal DMV dorsomed hy nu, ventral DS dorsal subiculum Ect ectorhinal cortex eml external medullary lamina f fornix FC fasciola cinereum fi fimbria hippocampus fr fasciculus retroflexus GrDG granular dentate gyrus hif hippocampal fissure I intercalated nuclei amyg ic internal capsule ictd internal carotid artery IG indusium griseum IGL intergeniculate leaf IMA intramedullary thalamic area IMD intermediodorsal thal nu LaDL lat amyg nu, dorsolat LaVM lat amyg nu, ventromed LEnt lateral entorhinal cx LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LV lateral ventricle MCLH magnocell nu lat hypothal MDL mediodorsal thalamic nu, lat MDM mediodorsal thal nu, med MEE medial eminence, ext layer MEI medial eminence, internal layer MePD med amygd nu, posterodors MHb med habenular nu MoDG molecular dentate gyrus mt mammillothalamic tract MTu medial tuberal nu ne neuroepithelium OPC oval paracentral thal nu opt optic tract Or oriens layer hippocampus Pe periventricular hypothal nu PeF perifornical nu PeFLH perifornical part of lat hy PHD post hypothal area, dorsal Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus PRh perirhinal cx PTe paraterete nu PtPD parietal cx, post, dorsal PtPR parietal cx, post, rostral PVP paraventricular thal nu, post Py pyramidal cell hippocampus Rad radiatum layer hippocamp RAPir rostral amygdalopiriform rf rhinal fissure RRe retrouniens area RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c scc splenium corpus callosum SLu stratum lucidum hippocamp sox supraoptic decussation st stria terminalis STh subthalamic nu STIA ST, intraamygdaloid div str superior thalamic radiation Refer to Index of Abbreviations for other entries

Figure 136 P6 #33 5.31 mm

V2MM

RSD

V2ML

V1

RSGc

V2L cg

alv

PtPD Or Py

PtPC

fmj RSGb

Rad AuD

MoDG

Au1

dhc

LMol

DS

hif

D3V

GrDG PoDG

dcw

bsc

AuV

LHbM

IMA LPLR

MHb

LPMR

CA2

LHbL fr fr

Po

PoMn

PF

Ect

VG

SLu

OPC

VPL

sox

DLEnt

MDM

VPM

PRh rf

PVP

iml

IGL

3V

CL

DLG TeA

hbc

CM

CA3 SubG

VPPC

DEn

fi ne LV

LaDL LaVM

ZID ic

mt

A11

PSTh

I STIA

3 Pir1 2

PH

MePD BMP

I PLH

BLV

DMD PeF

AHiAL

RAPir

Pe

PTe

DMC DMV

f

PMCo PLCo

PHD

VM scp

ZIV STh

st BLP

RRe

ml

opt

Te

PeFLH MTu VMHSh

VMHDM VMHVL ArcD VMHC

ArcM ArcL MEE

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

MEI

3V 3rd ventricle A11 A11 dopamine cells AHiAL amygdalohip area, antlat alv alveus hippocampus ArcD arcuate hypothal nu, dors ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post BLV basolat amyg, ventral BMP basomed amyg nu, post bsc brachium superior colliculus cg cingulum CL centrolateral thal nu CM central medial thal nu D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DLG dorsal lat geniculate nu DMC dorsomed hy nu, compact DMD dorsomed hypothal nu,dorsal DMV dorsomed hy nu, ventral DS dorsal subiculum Ect ectorhinal cortex f fornix fi fimbria hippocampus fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus hbc habenular commissure hif hippocampal fissure I intercalated nuclei amyg ic internal capsule IGL intergeniculate leaf IMA intramedullary thalamic area iml int medullary lamina LaDL lat amyg nu, dorsolat LaVM lat amyg nu, ventromed LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LV lateral ventricle MDM mediodorsal thal nu, med MEE medial eminence, ext layer MEI medial eminence, internal layer MePD med amygd nu, posterodors MHb med habenular nu ml medial lemniscus MoDG molecular dentate gyrus mt mammillothalamic tract MTu medial tuberal nu ne neuroepithelium OPC oval paracentral thal nu opt optic tract Or oriens layer hippocampus Pe periventricular hypothal nu PeF perifornical nu PeFLH perifornical part of lat hy PF parafascicular thal nu PH posterior hypothal nu PHD post hypothal area, dorsal Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus PoMn posteromedian thal nu PRh perirhinal cx PSTh parasubthalamic nu PTe paraterete nu PtPC parietal cx, post, caudal PtPD parietal cx, post, dorsal PVP paraventricular thal nu, post Py pyramidal cell hippocampus Rad radiatum layer hippocamp RAPir rostral amygdalopiriform rf rhinal fissure RRe retrouniens area RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c scp superior Cb peduncle SLu stratum lucidum hippocamp sox supraoptic decussation st stria terminalis Refer to Index of Abbreviations for other entries

Figure 137 P6 #34 5.43 mm

RSD

V2MM

V2ML V1

cg V2L

fmj

Or Py

LV

PtPC

RSGc

alv

dhc

Rad AuD

RSGb

LMol

DS

MoDG GrDG

CA1

Au1

PoDG IMA

MHb

LPMR

LPLR

hif

AuV

hbc

APT

bsc

CL

LHbL LHbM PVP

DLG TeA

dcw

str

IGL

3V

Po fr

CA3

Ect

VPL

VG 3 2 1

PRh

SubG DEn

CA3

sox ic

opt

LaDL 2

VPPC

ZID

ml

SLu

ne

3

PF

eml

DLEnt CA2

VPM

SPF

ZIV

PR scp ns

STh LV

LaVM

Pir1 RAPir

PH

PSTh cp

PLH

BMP AHiAL

mt

mfb MePD

BLP

A11

MePV PMCo

PeF

PeFLH

Pe

f

PLCo Te

DM

TuLH VMH

MTu

ArcD 3V

ArcL ArcM MEE MEI

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A11 A11 dopamine cells AHiAL amygdalohip area, antlat alv alveus hippocampus APT anterior pretectal nu ArcD arcuate hypothal nu, dors ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post BMP basomed amyg nu, post bsc brachium superior colliculus cg cingulum CL centrolateral thal nu cp cerebral peduncle dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DLG dorsal lat geniculate nu DM dorsomed hypothal nu DS dorsal subiculum Ect ectorhinal cortex eml external medullary lamina f fornix fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus hbc habenular commissure hif hippocampal fissure ic internal capsule IGL intergeniculate leaf IMA intramedullary thalamic area LaDL lat amyg nu, dorsolat LaVM lat amyg nu, ventromed LHbL lateral habenular nu, lateral LHbM lateral habenular nu, medial LMol lacunosum moleculare LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral LV lateral ventricle MEE medial eminence, ext layer MEI medial eminence, internal layer MePD med amygd nu, posterodors MePV med amyg nu, posterovent mfb med forebrain bundle MHb med habenular nu ml medial lemniscus MoDG molecular dentate gyrus mt mammillothalamic tract MTu medial tuberal nu ne neuroepithelium ns nigrostriatal bundle opt optic tract Or oriens layer hippocampus Pe periventricular hypothal nu PeF perifornical nu PeFLH perifornical part of lat hy PF parafascicular thal nu PH posterior hypothal nu Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus PR prerubral field PRh perirhinal cx PSTh parasubthalamic nu PtPC parietal cx, post, caudal PVP paraventricular thal nu, post Py pyramidal cell hippocampus Rad radiatum layer hippocamp RAPir rostral amygdalopiriform RSD retrosplenial dysgranular cx RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c scp superior Cb peduncle SLu stratum lucidum hippocamp sox supraoptic decussation SPF subparafascicular thal nu STh subthalamic nu str superior thalamic radiation SubG subgeniculate nu Te terete hypothal nu TeA temporal associatin cx TuLH tuberal region lat hy V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat Refer to Index of Abbreviations for other entries

Figure 138 P6 #35 5.55 mm

V1B

V2MM

V2ML

V1M

cg

V2L PtPC

RSGc

fmj alv

AuD

Or Py Rad

dhc

DS

MoDG

RSGb

RSGa

LMol

Au1

AuV

RSD

GrDG bsc LPMR

PoDG dcw

D3V

APT

pc SCO

LPLR IMA

PrC

D3V

hif TeA

DLG IGL

CA1

Ect

str

PF

VPL

VG

fr

VPM

CA3

PRh

Po

eml SPFPC

DLEnt

SubG

VPPC

ZID SPF ZIV

DEn

PR

ic CA2 2 Pir1

A11

SLu

3V

3 LaVM

STh BLP

PSTh

PH

FF ns mfb

mt SMT

cp BMP

AHiAL

PLH

APir PLCo

PeFLH

PMCo

Pe

f Te

af

DM MTu

3V

TuLH VMH ArcL

ArcM MEI MEE

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A11 A11 dopamine cells af amygdaloid fissure AHiAL amygdalohip area, antlat alv alveus hippocampus APir amygdalopiriform transition APT anterior pretectal nu ArcL arcuate hypothal nu, lat ArcM arcuate hypothal nu,med Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post BMP basomed amyg nu, post bsc brachium superior colliculus cg cingulum cp cerebral peduncle D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DLG dorsal lat geniculate nu DM dorsomed hypothal nu DS dorsal subiculum Ect ectorhinal cortex eml external medullary lamina f fornix FF fields of Forel fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus hif hippocampal fissure ic internal capsule IGL intergeniculate leaf IMA intramedullary thalamic area LaVM lat amyg nu, ventromed LMol lacunosum moleculare LPLR LP thal nu, laterorostral LPMR LP thal nu, mediorostral MEE medial eminence, ext layer MEI medial eminence, internal layer mfb med forebrain bundle MoDG molecular dentate gyrus mt mammillothalamic tract MTu medial tuberal nu ns nigrostriatal bundle Or oriens layer hippocampus pc posterior comm Pe periventricular hypothal nu PeFLH perifornical part of lat hy PF parafascicular thal nu PH posterior hypothal nu Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus PR prerubral field PrC precommissural nu PRh perirhinal cx PSTh parasubthalamic nu PtPC parietal cx, post, caudal Py pyramidal cell hippocampus Rad radiatum layer hippocamp RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c SCO subcommissural organ SLu stratum lucidum hippocamp SMT submammillothalamic nu SPF subparafascicular thal nu SPFPC subparafascicular, parvicell STh subthalamic nu str superior thalamic radiation SubG subgeniculate nu Te terete hypothal nu TeA temporal associatin cx TuLH tuberal region lat hy V1B primary visual cx, binocular V1M prim visual cx, monocular V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VG ventral geniculate nu VMH ventmed hypothal nu VPL ventral posterolat thal nu VPM vent posteromed thal nu VPPC vent post nu th, parvicellular ZID zona incerta, dorsal ZIV zona incerta, ventral

Figure 139 P6 #36 5.67 mm

V2MM

V2ML

V1M

RSD

V1B V2L PtPC

fmj

LV alv

AuD

RSGc

dhc DS

Au1

Py Rad

Or

D3V

MoDG

LMol

dcw

RSGb

RSGa

GrDG

OPT MPT pc

APTD

bsc

SCO

AuV LP

PoDG TeA

APTV p1PAG

DLG

CA3

CA1

PrC

IMA

Po hif

str

IGL

Ect

PF VPM

PRh

fr

VG

SPFPC

sox 2 3

ic

ml

VLi

SubG

DEn

Pir1

VPPC

ZID

DLEnt

3V

ZIV

PR F

CA2 LaVM

ns mfb

SLu BLP

mt

PSTh

PHA

PLH

AHiPM

PLCo af

Gem

STh cp

AHiPL

PH

FF

SNR

APir

A11

SPF

PMD

GrDG PMCo

Te

f

DTM

TuLH

DM

PMV

3V

MTu ArcLP

ArcMP

Inf

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A11 A11 dopamine cells af amygdaloid fissure AHiPL amygdalohip area, postlat AHiPM amygdalohip, posteromed alv alveus hippocampus APir amygdalopiriform transition APTD ant pretectal nu, dors APTV ant pretectal nu, ventral ArcLP arcuate hy nu, lateropost ArcMP arcuate hy nu, med post Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post bsc brachium superior colliculus cp cerebral peduncle D3V dorsal 3rd ventricle dcw deep cerebral white DEn dorsal endopiriform nu dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DLG dorsal lat geniculate nu DM dorsomed hypothal nu DS dorsal subiculum DTM dors tuberomammillary nu Ect ectorhinal cortex F nu fields of Forel f fornix FF fields of Forel fmj forceps maj corpus call fr fasciculus retroflexus Gem gemini hypothalamic nu GrDG granular dentate gyrus hif hippocampal fissure ic internal capsule IGL intergeniculate leaf IMA intramedullary thalamic area Inf infundibulum LaVM lat amyg nu, ventromed LMol lacunosum moleculare LP lateral posterior thal nu LV lateral ventricle mfb med forebrain bundle ml medial lemniscus MoDG molecular dentate gyrus MPT medial pretectal nu mt mammillothalamic tract MTu medial tuberal nu ns nigrostriatal bundle OPT olivary pretectal nu Or oriens layer hippocampus p1PAG p1 periaqueductal gray pc posterior comm PF parafascicular thal nu PH posterior hypothal nu PHA posterior hypothal area Pir1 piriform cx, layer 1 PLCo posterolat cortical amyg PLH peduncular part lat hy PMCo posteromed cortical amyg nu PMD premammillary nu, dors PMV premammillary nu, vent Po post thal nuclear group PoDG polymorph dentate gyrus PR prerubral field PrC precommissural nu PRh perirhinal cx PSTh parasubthalamic nu PtPC parietal cx, post, caudal Py pyramidal cell hippocampus Rad radiatum layer hippocamp RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c SCO subcommissural organ SLu stratum lucidum hippocamp SNR s nigra, reticular sox supraoptic decussation SPF subparafascicular thal nu SPFPC subparafascicular, parvicell STh subthalamic nu str superior thalamic radiation SubG subgeniculate nu Te terete hypothal nu TeA temporal associatin cx TuLH tuberal region lat hy V1B primary visual cx, binocular V1M prim visual cx, monocular V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat Refer to Index of Abbreviations for other entries

Figure 140 P6 #37 5.79 mm

RSD

V2MM

V2ML

V1M V1B V2L

RSGc

fmj LV

AuD

dhc DS

RSGb

RSGa Au1

alv

OT

bsc

dcw

OPT

MPT

APTD

GrDG

pc E

AuV LP

Py PoDG

Rad Or LMol

TeA

MGV IGL

hif CA3

PRh

Po str

p1PAG

Sc p1Rt

Eth

3V

VPM

ZIC

VG opt

PrC

MCPC APTV

MGD

MoDG

CA1

Ect

SCO

DLG

PF SPFPC fr

ZID ml

ZIV

SubG DLEnt

VLi

ic SNCD

PSTh

AHiPM af

PHA

SuML pm

cp

AHiPL

PH

Gem

APir PLCo

A11

mtg

SNR

SLu

BLP

RI

PR

F

SuML

VS

SuMM

PLH

MoDG

PMCo

f

Te a

MTu

PMD

DTM

TuLH PMV

VTM

MRe

ArcLP ArcMP

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle a artery A11 A11 dopamine cells af amygdaloid fissure AHiPL amygdalohip area, postlat AHiPM amygdalohip, posteromed alv alveus hippocampus APir amygdalopiriform transition APTD ant pretectal nu, dors APTV ant pretectal nu, ventral ArcLP arcuate hy nu, lateropost ArcMP arcuate hy nu, med post Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral BLP basolat amyg nu, post bsc brachium superior colliculus cp cerebral peduncle dcw deep cerebral white dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DLG dorsal lat geniculate nu DS dorsal subiculum DTM dors tuberomammillary nu E ependyma/ subependymal Ect ectorhinal cortex Eth ethmoid thalamic nu F nu fields of Forel f fornix fmj forceps maj corpus call fr fasciculus retroflexus Gem gemini hypothalamic nu GrDG granular dentate gyrus hif hippocampal fissure ic internal capsule IGL intergeniculate leaf LMol lacunosum moleculare LP lateral posterior thal nu LV lateral ventricle MCPC magnocell nu post comm MGD med geniculate nu, dorsal MGV med geniculate nu, ventral ml medial lemniscus MoDG molecular dentate gyrus MPT medial pretectal nu MRe mammillary recess 3V mtg mammillotegmental tract MTu medial tuberal nu OPT olivary pretectal nu opt optic tract Or oriens layer hippocampus OT nu of the optic tract PAG periaqueductal gray pc posterior comm PF parafascicular thal nu PH posterior hypothal nu PHA posterior hypothal area PLCo posterolat cortical amyg PLH peduncular part lat hy pm principal mammillary tr PMCo posteromed cortical amyg nu PMD premammillary nu, dors PMV premammillary nu, vent Po post thal nuclear group PoDG polymorph dentate gyrus PR prerubral field PrC precommissural nu PRh perirhinal cx PSTh parasubthalamic nu Py pyramidal cell hippocampus Rad radiatum layer hippocamp RI rostral interstitial nu of mlf RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c Rt reticular thal nu Sc scaphoid thal nu SCO subcommissural organ SLu stratum lucidum hippocamp SNCD s nigra, compact, dors tier SNR s nigra, reticular SPFPC subparafascicular, parvicell str superior thalamic radiation SubG subgeniculate nu SuML supramammillary nu, lat SuMM supramammillary nu, medial Te terete hypothal nu TeA temporal associatin cx TuLH tuberal region lat hy V1B primary visual cx, binocular V1M prim visual cx, monocular Refer to Index of Abbreviations for other entries

Figure 141 P6 #38 5.91 mm

V2MM

V2ML

RSD

V1 fmj

RSGc

LV

V2L

dhc AuD

RSGb

RSGa

DS Au1

OPT MPT

OT AuV

Rad LMol

Py TeA Ect

GrDG

Or

APT

LP

MoDG

PLi PoDG

MGD

MCPC

PrC

SCO

str 3V

CA1

alv

pc

PCom

Po

MGV MGM

hif

PRh

Sc VPM

rf opt

Lth

p1Rt

p1PAG

Eth

PIL

IGL

VG

RPF

A11 SPFPC

SubG

ZIC

fr

PR

ZIV

RI

DLEnt

ml CA3 SNCD

SLu AHiPM

mtg

PBP

SNR APir

PH

FF ns

Gem

PHA

PLH

VS

pm

cp

SuMM

SuML af

PMCo

MoDG

LM

a

ML MM MnM

f

PMD

VTM

MRe ArcLP ArcMP

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle a artery A11 A11 dopamine cells af amygdaloid fissure AHiPM amygdalohip, posteromed alv alveus hippocampus APir amygdalopiriform transition APT anterior pretectal nu ArcLP arcuate hy nu, lateropost ArcMP arcuate hy nu, med post Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral cp cerebral peduncle dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DS dorsal subiculum Ect ectorhinal cortex Eth ethmoid thalamic nu f fornix FF fields of Forel fmj forceps maj corpus call fr fasciculus retroflexus Gem gemini hypothalamic nu GrDG granular dentate gyrus hif hippocampal fissure IGL intergeniculate leaf LM lateral mammillary nu LMol lacunosum moleculare LP lateral posterior thal nu Lth lithoid nu LV lateral ventricle MCPC magnocell nu post comm MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MnM medial mammillary nu, med MoDG molecular dentate gyrus MPT medial pretectal nu MRe mammillary recess 3V mtg mammillotegmental tract ns nigrostriatal bundle OPT olivary pretectal nu opt optic tract Or oriens layer hippocampus OT nu of the optic tract PAG periaqueductal gray PBP parabrachial pigmented nu pc posterior comm PCom nu posterior comm PH posterior hypothal nu PHA posterior hypothal area PIL post intralaminar thal nu PLH peduncular part lat hy PLi posterior limitans thal nu pm principal mammillary tr PMCo posteromed cortical amyg nu PMD premammillary nu, dors Po post thal nuclear group PoDG polymorph dentate gyrus PR prerubral field PrC precommissural nu PRh perirhinal cx Py pyramidal cell hippocampus Rad radiatum layer hippocamp rf rhinal fissure RI rostral interstitial nu of mlf RPF retroparafascicular nu RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b RSGc retrosplenial granular cx, c Sc scaphoid thal nu SCO subcommissural organ SLu stratum lucidum hippocamp SNCD s nigra, compact, dors tier SNR s nigra, reticular SPFPC subparafascicular, parvicell str superior thalamic radiation SubG subgeniculate nu SuML supramammillary nu, lat SuMM supramammillary nu, medial TeA temporal associatin cx V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VG ventral geniculate nu VPM vent posteromed thal nu Refer to Index of Abbreviations for other entries

Figure 142 P6 #39 6.03 mm

V2MM

V2ML V1

RSD fmj

V2L AuD

dhc

LV

RSGb RSGa

Au1

Post

DS

MPT

PPT OPT OT

SC

TG

AuV dcw

MGD Ect PRh

Or LMol

MCPC

PLi

p1PAG

DLEnt

p1Rt

Eth

A11

REth

CA3

PR

ml

fr

SNL SLu

APir

LV

RI SNCD PBP

PHA

sumx

PLH

VS

PMCo

mtg FF

SNR

cp

SuML

AHiPM af

3V Lth

PoT MZMG PIL PP ZIC LT EpP SPFPC

Rad Py

Po SG

MGV MGM

PoDG CA1

pc

APT

GrDG

TeA

rf

PCom

LP

alv

VTM MoDG LM

SuMM MnM

pm f ML

MM

ArcMP MRe

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3V 3rd ventricle A11 A11 dopamine cells af amygdaloid fissure AHiPM amygdalohip, posteromed alv alveus hippocampus APir amygdalopiriform transition APT anterior pretectal nu ArcMP arcuate hy nu, med post Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral cp cerebral peduncle dcw deep cerebral white dhc dorsal hippocampal comm DLEnt dorsolateral entorhinal cx DS dorsal subiculum Ect ectorhinal cortex EpP epipeduncular nu Eth ethmoid thalamic nu f fornix FF fields of Forel fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus LM lateral mammillary nu LMol lacunosum moleculare LP lateral posterior thal nu LT lat terminal nu acc optic tr Lth lithoid nu LV lateral ventricle MCPC magnocell nu post comm MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MnM medial mammillary nu, med MoDG molecular dentate gyrus MPT medial pretectal nu MRe mammillary recess 3V mtg mammillotegmental tract MZMG marg zone med geniculate OPT olivary pretectal nu Or oriens layer hippocampus OT nu of the optic tract PAG periaqueductal gray PBP parabrachial pigmented nu pc posterior comm PCom nu posterior comm PHA posterior hypothal area PIL post intralaminar thal nu PLH peduncular part lat hy PLi posterior limitans thal nu pm principal mammillary tr PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus Post postsubiculum PoT posterior thal nu, triangular PP peripeduncular nu PPT posterior pretectal nu PR prerubral field PRh perirhinal cx Py pyramidal cell hippocampus Rad radiatum layer hippocamp REth retroethmoid nu rf rhinal fissure RI rostral interstitial nu of mlf RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b Rt reticular thal nu SC superior colliculus SG suprageniculate thal nu SLu stratum lucidum hippocamp SNCD s nigra, compact, dors tier SNL s nigra, lateral SNR s nigra, reticular SPFPC subparafascicular, parvicell SuML supramammillary nu, lat SuMM supramammillary nu, medial sumx supramammillary decuss TeA temporal associatin cx TG tectal gray V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VS ventral subiculum VTM vent tuberomammillary nu ZIC zona incerta, caudal

Figure 143 P6 #40 6.15 mm

V2MM

V2ML V1M V1B

RSD

fmj RSGb

V2L LV

AuD

RSGa

dhc

Zo SuG OT

Au1

Post

DS

Op

PPT OPT

AuV

InWh

MGD SG

MoDG Ect rf

dcw

PlPAG PCom p1PAG pc p1Rt Aq MCPC

Po APTD PLi

alv GrDG

PRh

MGV MGM

PoT

csc

DpG

TG

LP TeA

PaC

InG

Lth APTV Dk

PIL

PP

mRt SPFPC

PoDG DLEnt

EpP

ZIC SNL

CA3

ml

mtg

PR fr

SNCD

RLi

PBP VTAR SNR

sumx PLH

APir AHiPM

SuMM

VS cp

SuML VTM

4n af

pm

mp

PMCo

LM

3n

MM f

s5

ML

5Gn m5 APit IPit

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

PPit

3n oculomotor nerve 4n trochlear nerve 5Gn trigeminal ganglion af amygdaloid fissure AHiPM amygdalohip, posteromed alv alveus hippocampus APir amygdalopiriform transition APit anterior lobe pituitary APTD ant pretectal nu, dors APTV ant pretectal nu, ventral Aq aqueduct Au1 primary auditory cortex AuD 2ary auditory cx, dorsal AuV 2ary auditory cx, ventral cp cerebral peduncle csc comm superior colliculus dcw deep cerebral white dhc dorsal hippocampal comm Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DpG deep gray superior coll DS dorsal subiculum Ect ectorhinal cortex EpP epipeduncular nu f fornix fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus InG intermed gray layer SC InWh intermediate white layer SC IPit intermediate lobe pit LM lateral mammillary nu LP lateral posterior thal nu Lth lithoid nu LV lateral ventricle m5 motor root trigeminal nerve MCPC magnocell nu post comm MGD med geniculate nu, dorsal MGM med geniculate nu, medial MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MoDG molecular dentate gyrus mp mammillary peduncle mRt mesenceph reticular formation mtg mammillotegmental tract Op optic nerve layer sup coll OPT olivary pretectal nu OT nu of the optic tract p1PAG p1 periaqueductal gray PaC paracomm nu post com PBP parabrachial pigmented nu pc posterior comm PCom nu posterior comm PIL post intralaminar thal nu PLH peduncular part lat hy PLi posterior limitans thal nu PlPAG pleoglial PAG pm principal mammillary tr PMCo posteromed cortical amyg nu Po post thal nuclear group PoDG polymorph dentate gyrus Post postsubiculum PoT posterior thal nu, triangular PP peripeduncular nu PPit posterior lobe pit PPT posterior pretectal nu PR prerubral field PRh perirhinal cx rf rhinal fissure RLi rostral linear nu raphe RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b s5 sensory root trigem n SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNL s nigra, lateral SNR s nigra, reticular SPFPC subparafascicular, parvicell SuG superficial gray sup coll SuML supramammillary nu, lat SuMM supramammillary nu, medial sumx supramammillary decuss TeA temporal associatin cx TG tectal gray V1B primary visual cx, binocular V1M prim visual cx, monocular V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed Refer to Index of Abbreviations for other entries

Figure 144 P6 #41 6.27 mm

V2ML

V2MM RSD

V1 fmj

RSGb RSGa

LV

Pi

Zo

V2L SuG Op

dhc

AuD

PaC

Post

csc

InG DS

InWh

TeA dcw MGD

Ect

TG

LP SG bic Po

rf

PRh

alv

PlPAG

PCom DpWh

pc

p1Rt

APT PLi

MGV

DMPAG

DpG

Aq p1PAG MCPC

PoT MoDG

SubB

Dk mRt

PIL

InC

GrDG RPC

SNL

DLEnt

ml

PBP

mtg PoDG VS APir

RLi

SNCD fr

PBP MT

SNR

VTAR

IF

PaS SuMM

AHiPM cp

SuML

VTM LM

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

MM

mp ML

0.6

0.8

1.0 mm

AHiPM amygdalohip, posteromed alv alveus hippocampus APir amygdalopiriform transition APT anterior pretectal nu Aq aqueduct AuD 2ary auditory cx, dorsal bic brachium inf colliculus cp cerebral peduncle csc comm superior colliculus dcw deep cerebral white dhc dorsal hippocampal comm Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DS dorsal subiculum Ect ectorhinal cortex fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC LM lateral mammillary nu LP lateral posterior thal nu LV lateral ventricle MCPC magnocell nu post comm MGD med geniculate nu, dorsal MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus MM med mammillary nu, medial MoDG molecular dentate gyrus mp mammillary peduncle mRt mesenceph reticular formation MT med terminal nu acc optic tr mtg mammillotegmental tract Op optic nerve layer sup coll p1PAG p1 periaqueductal gray PaC paracomm nu post com PaS parasubiculum PBP parabrachial pigmented nu pc posterior comm PCom nu posterior comm Pi pineal gland PIL post intralaminar thal nu PLi posterior limitans thal nu PlPAG pleoglial PAG Po post thal nuclear group PoDG polymorph dentate gyrus Post postsubiculum PoT posterior thal nu, triangular PRh perirhinal cx rf rhinal fissure RLi rostral linear nu raphe RPC red nu, parvicell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNL s nigra, lateral SNR s nigra, reticular SubB subbrachial nu SuG superficial gray sup coll SuML supramammillary nu, lat SuMM supramammillary nu, medial TeA temporal associatin cx TG tectal gray V1 primary visual cortex V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VS ventral subiculum VTAR vent tegmental area, rostr VTM vent tuberomammillary nu Zo zona layer sup coll

Figure 145 P6 #42 6.39 mm

V2MM

V2ML

RSD V1B Pi

RSGb fmj RSGa

SuG Op

Zo

V2L LV

InG

dhc Post

TeA

InWh DMPAG DpG

Ect

LP

DS

PrS

PRh dcw

rf

alv

SG MGD bic MGV

DLEnt PaS

SubB

TG

Po PLi

DpWh

VIEnt

Aq

mRt

PoT

Dk InC

PIL

MA3 PrEW

RPC mlf

ml

MoDG GrDG

LPAG

APT

SNL DIEnt

DLPAG PlPAG

mtg

RMC scp MT

SNCD

PBP

VS

VTAR fr

SNR MEnt

SNCD

IPR IPC

SNCV CEnt

RLi IF

IPF SuMM

cp SuML

ML

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

alv alveus hippocampus APT anterior pretectal nu Aq aqueduct bic brachium inf colliculus CEnt caudomed entothinal cx cp cerebral peduncle dcw deep cerebral white dhc dorsal hippocampal comm DIEnt dorsintermed entorhinal cx Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DS dorsal subiculum Ect ectorhinal cortex fmj forceps maj corpus call fr fasciculus retroflexus GrDG granular dentate gyrus IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPC IPC nu, caudal IPF interpedunc fossa IPR interpedunc nu, rostral sub LP lateral posterior thal nu LPAG lat periaqueductal gray LV lateral ventricle MA3 med access oculomotor nu MEnt med entorhinal cx MGD med geniculate nu, dorsal MGV med geniculate nu, ventral ML med mammillary nu, lat ml medial lemniscus mlf med longitudinal fasciculus MoDG molecular dentate gyrus mRt mesenceph reticular form MT med terminal nu acc optic tr mtg mammillotegmental tract Op optic nerve layer sup coll PaS parasubiculum PBP parabrachial pigmented nu Pi pineal gland PIL post intralaminar thal nu PLi posterior limitans thal nu PlPAG pleoglial PAG Po post thal nuclear group Post postsubiculum PoT posterior thal nu, triangular PrEW pre-Edinger-Westphal nu PRh perirhinal cx PrS presubiculum rf rhinal fissure RLi rostral linear nu raphe RMC red nu, magnocell part RPC red nu, parvicell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a RSGb retrosplenial granular cx, b scp superior Cb peduncle SG suprageniculate thal nu SNCD s nigra, compact, dors tier SNCV s nigra, compact, vent tier SNL s nigra, lateral SNR s nigra, reticular SubB subbrachial nu SuG superficial gray sup coll SuML supramammillary nu, lat SuMM supramammillary nu, medial TeA temporal associatin cx TG tectal gray V1B primary visual cx, binocular V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VIEnt ventral intermed entorhinal VS ventral subiculum VTAR vent tegmental area, rostr Zo zona layer sup coll

Figure 146 P6 #43 6.51 mm

V2ML

V2MM

Pi

RSD

V1M RSGa

V1B

SuG

Zo Op

V2L

Post InG

TeA

Post

DpG DMPAG PlPAG DLPAG

LV DS

Ect rf

dcw alv

PRh

DpWh

InWh

Aq LPAG

APT PrS

BIC bic

DLEnt

InC

mRt

Dk

SubB

MA3

RPC

DIEnt SNL VS VIEnt

mlf RMC

PaS

ml DG

cp

4n

RLi vtgx IF

PIF PN SNCM

CEnt

scp mtg

PBP

SNCD SNR

MEnt

PrEW

mp IPF v

IPR

fr IPL

IPC

3n

s5

Pn

m5

bas

ptgpal 5Gn

6n APit

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 4n trochlear nerve 5Gn trigeminal ganglion 6n root of abducens nerve alv alveus hippocampus APit anterior lobe pituitary APT anterior pretectal nu Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CEnt caudomed entothinal cx cp cerebral peduncle dcw deep cerebral white DG dentate gyrus DIEnt dorsintermed entorhinal cx Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DS dorsal subiculum Ect ectorhinal cortex fr fasciculus retroflexus IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPC IPC nu, caudal IPF interpedunc fossa IPL interpedunc nu, lat subnu IPR interpedunc nu, rostral sub LPAG lat periaqueductal gray LV lateral ventricle m5 motor root trigeminal nerve MA3 med access oculomotor nu MEnt med entorhinal cx ml medial lemniscus mlf med longitudinal fasciculus mp mammillary peduncle mRt mesenceph reticular form mtg mammillotegmental tract Op optic nerve layer sup coll PaS parasubiculum PBP parabrachial pigmented nu Pi pineal gland PIF parainterfascicular nu VTA PlPAG pleoglial PAG PN paranigral nu of the VTA Pn pontine nuclei Post postsubiculum PrEW pre-Edinger-Westphal nu PRh perirhinal cx PrS presubiculum ptgpal pterygopalatine n rf rhinal fissure RLi rostral linear nu raphe RMC red nu, magnocell part RPC red nu, parvicell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a s5 sensory root trigem n scp superior Cb peduncle SNCD s nigra, compact, dors tier SNCM s nigra, compact, med tier SNL s nigra, lateral SNR s nigra, reticular SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx v vein V1B primary visual cx, binocular V1M prim visual cx, monocular V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VIEnt ventral intermed entorhinal VS ventral subiculum vtgx vent tegmental decussation Zo zona layer sup coll

Figure 147 P6 #44 6.63 mm

V2MM

Pi

RSD

V2ML

Zo V1M

SuG

RSGa Op

V1B InG

V2L Post

TeA

InWh

Ect DpG

rf

PRh

dcw alv

DMPAG

DpWh

bic PrS

DLEnt

LPAG Aq

BIC mRt

DIEnt

PlPAG

DLPAG

DS

Dk MA3 InC

SubB

VS

PaR RPC

VIEnt PaS

PrEW

mlf

RMC scp mtg RLi

SNCD

MEnt

IF

PBP

SNR

PIF

CEnt

PN

SNCM ml 3n

cp

IPDL

mp

IPL

a 4n

IPDM IPR

IPC

lfp mcp tfp

ptgpal s5

Pn

m5

5Gn

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

bas

0

0.2

0.4

0.6

0.8

1.0 mm

3n oculomotor nerve 4n trochlear nerve 5Gn trigeminal ganglion a artery alv alveus hippocampus Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CEnt caudomed entothinal cx cp cerebral peduncle dcw deep cerebral white DIEnt dorsintermed entorhinal cx Dk nu of Darkschewitsch DLEnt dorsolateral entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DS dorsal subiculum Ect ectorhinal cortex IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPC IPC nu, caudal IPDL interpedunc nu, dorsolat IPDM interpedunc nu, dorsomed IPL interpedunc nu, lat subnu IPR interpedunc nu, rostral sub lfp longitudinal fasciculus pons LPAG lat periaqueductal gray m5 motor root trigeminal nerve MA3 med access oculomotor nu mcp middle cerebellar peduncle MEnt med entorhinal cx ml medial lemniscus mlf med longitudinal fasciculus mp mammillary peduncle mRt mesenceph reticular form mtg mammillotegmental tract Op optic nerve layer sup coll PaR pararubral nu PaS parasubiculum PBP parabrachial pigmented nu Pi pineal gland PIF parainterfascicular nu VTA PlPAG pleoglial PAG PN paranigral nu of the VTA Pn pontine nuclei Post postsubiculum PrEW pre-Edinger-Westphal nu PRh perirhinal cx PrS presubiculum ptgpal pterygopalatine n rf rhinal fissure RLi rostral linear nu raphe RMC red nu, magnocell part RPC red nu, parvicell part RSD retrosplenial dysgranular cx RSGa retrosplenial granular cx, a s5 sensory root trigem n scp superior Cb peduncle SNCD s nigra, compact, dors tier SNCM s nigra, compact, med tier SNR s nigra, reticular SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx tfp transverse fibers pons V1B primary visual cx, binocular V1M prim visual cx, monocular V2L 2ary visual cx, lat area V2ML 2ary visual cx, mediolat V2MM 2ary visual cx, mediomed VIEnt ventral intermed entorhinal VS ventral subiculum Zo zona layer sup coll

Figure 148 P6 #45 6.75 mm

Pi

RSD

V2MM

Zo SuG

V1 RSG

V2L

Op

TeA

InG

Ect

InWh

Post

PRh

dcw

rf

DMPAG

DpG

DS

DLPAG

bic

DpWh

LEnt PrS

plPAG Aq

LPAG

BIC mRt

Dk

SubB PaR

SNL DIEnt

EW

InC

3N

VS

mlf

PaS

RMC

scp RL vtgx

MEnt SNR

PBP

PIF

SNCD

CEnt

PN

PnO

ml ll

IF

cp

pcer

IPDM IPR IPDL IPI

IPL

IPC

MPL tth ml lfp

VLL m5

mcp

s5 Pn

tfp bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

3N oculomotor nu Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CEnt caudomed entothinal cx cp cerebral peduncle dcw deep cerebral white DIEnt dorsintermed entorhinal cx Dk nu of Darkschewitsch DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DS dorsal subiculum Ect ectorhinal cortex EW Edinger-Westphal nu IF interfascicular nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPC IPC nu, caudal IPDL interpedunc nu, dorsolat IPDM interpedunc nu, dorsomed IPI interpedunc nu, intermed IPL interpedunc nu, lat subnu IPR interpedunc nu, rostral sub LEnt lateral entorhinal cx lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MEnt med entorhinal cx ml medial lemniscus mlf med longitudinal fasciculus MPL medial paralemniscial nu mRt mesenceph reticular form Op optic nerve layer sup coll PaR pararubral nu PaS parasubiculum PBP parabrachial pigmented nu pcer post cerebral art Pi pineal gland PIF parainterfascicular nu VTA PlPAG pleoglial PAG PN paranigral nu of the VTA Pn pontine nuclei PnO pontine reticular nu, oral Post postsubiculum PRh perirhinal cx PrS presubiculum rf rhinal fissure RL retrolemniscal nu RMC red nu, magnocell part RSD retrosplenial dysgranular cx RSG retrosplenial granular cx s5 sensory root trigem n scp superior Cb peduncle SNCD s nigra, compact, dors tier SNL s nigra, lateral SNR s nigra, reticular SubB subbrachial nu SuG superficial gray sup coll TeA temporal associatin cx tfp transverse fibers pons tth trigeminothalamic tr V1 primary visual cortex V2L 2ary visual cx, lat area V2MM 2ary visual cx, mediomed VLL ventral nu lat lemniscus VS ventral subiculum vtgx vent tegmental decussation Zo zona layer sup coll

Figure 149 P6 #46 6.87 mm

Zo SuG

V2MM

RSD

V2L

Op

RSG InG

Ect

InWh

PRh

DpWh

Post

DMPAG

DpG

DLPAG LEnt dcw

LPAG

PrS bic

Aq

BIC mRt

DIEnt

PaS

PlPAG

Dk

SubB

Su3C Su3 3PC

InC PaR

MEnt

CEnt

EW

3N

SNCD

mlf DRV dtgx

RMC scp

SNR

CLi

RRF

SNCV

rs PBP xscp

SNCM

PIF

IPA

cp PnO

MPL ll

VLL

IPDL IPR IPL IPI IPC

ml

m5 s5 lfp

mcp

Pn tfp

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

bas

1.0 mm

3N oculomotor nu 3PC oculomotor nu, parvicellular Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CEnt caudomed entothinal cx CLi caudal linear nu raphe cp cerebral peduncle dcw deep cerebral white DIEnt dorsintermed entorhinal cx Dk nu of Darkschewitsch DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRV dorsal raphe nu, ventral dtgx dors tegmental decussation Ect ectorhinal cortex EW Edinger-Westphal nu InC interstitial nu of Cajal InG intermed gray layer SC InWh intermediate white layer SC IPA interpedunc nu, apical subnu IPC IPC nu, caudal IPDL interpedunc nu, dorsolat IPI interpedunc nu, intermed IPL interpedunc nu, lat subnu IPR interpedunc nu, rostral sub LEnt lateral entorhinal cx lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MEnt med entorhinal cx ml medial lemniscus mlf med longitudinal fasciculus MPL medial paralemniscial nu mRt mesenceph reticular form Op optic nerve layer sup coll PaR pararubral nu PaS parasubiculum PBP parabrachial pigmented nu PIF parainterfascicular nu VTA PlPAG pleoglial PAG Pn pontine nuclei PnO pontine reticular nu, oral Post postsubiculum PRh perirhinal cx PrS presubiculum RMC red nu, magnocell part RRF retrorubral field rs rubrospinal tract RSD retrosplenial dysgranular cx RSG retrosplenial granular cx s5 sensory root trigem n scp superior Cb peduncle SNCD s nigra, compact, dors tier SNCM s nigra, compact, med tier SNCV s nigra, compact, vent tier SNR s nigra, reticular Su3 supraoculomotor PAG Su3C supraoculomotor cap SubB subbrachial nu SuG superficial gray sup coll tfp transverse fibers pons V2L 2ary visual cx, lat area V2MM 2ary visual cx, mediomed VLL ventral nu lat lemniscus xscp decussation sup cereb ped Zo zona layer sup coll

Figure 150 P6 #47 6.99 mm

Zo SuG

V2MM

Op

V1 V2L

InG

Ect RSD

PRh

InWh Post

DMPAG

DpG

LEnt

DLPAG DpWh

bic BIC ECIC DIEnt

CEnt

PaS

PlPAG Aq

LPAG PrCnF

SubB

Su3 4Sh 4N mlf Pa4 DRV

mRt PBG MEnt

MiTg

cp

DRD

VLPAG

RRF/A8 CLi

ll

xscp

PTg

IPA IPI IPC

MPL PnO

MnR VLL

ts

rs ll

PMnR

mcp m5

RtTg

s5

tth ml

7n

lfp

ptgpal

Pn

tfp bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4N trochlear nu 4Sh trochlear nu shell region 7n facial nerve Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CEnt caudomed entothinal cx CLi caudal linear nu raphe cp cerebral peduncle DIEnt dorsintermed entorhinal cx DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral ECIC external cx inferior coll Ect ectorhinal cortex InG intermed gray layer SC InWh intermediate white layer SC IPA interpedunc nu, apical subnu IPC IPC nu, caudal IPI interpedunc nu, intermed LEnt lateral entorhinal cx lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MEnt med entorhinal cx MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu mRt mesencephalic retic form Op optic nerve layer sup coll Pa4 paratrochlear nu PaS parasubiculum PBG parabigeminal nu PlPAG pleoglial PAG PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Post postsubiculum PrCnF precuneiform area PRh perirhinal cx PTg pedunculopontine tegmental ptgpal pterygopalatine n RRF/A8 retrorubral/A8 dopamine rs rubrospinal tract RSD retrosplenial dysgranular cx RtTg reticulotegmental nu pons s5 sensory root trigem n Su3 supraoculomotor PAG SubB subbrachial nu SuG superficial gray sup coll tfp transverse fibers pons ts tectospinal tr tth trigeminothalamic tr V1 primary visual cortex V2L 2ary visual cx, lat area V2MM 2ary visual cx, mediomed VLL ventral nu lat lemniscus VLPAG ventlat periaqueductal gray xscp decussation sup cereb ped Zo zona layer sup coll

Figure 151 P6 #48 7.11 mm

Zo SuG Op V1

InG

V2L InWh

Ect RSD

PRh

DpG DMPAG DpWh

DLPAG PlPAG

PaS

bic

BIC

ECIC

LPAG

PrCnF

Aq

CEnt DRD

SubB

VLPAG

mRt

4Sh PBG

MiTg

4N mlf

RRF/A8 RR

ll

PTg

DRV CLi

xscp

ILL MPL PnO

Pr5 m5

VLL 5TT ll RtTg

PLV

s5

7n ptgpal

lfp

MVPO

TempP

Pn

0

0.2

0.4

tth ml tfp bas

mcp

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

PMnR MnR

rs

mcp

VeGn

ts

0.6

0.8

1.0 mm

4N trochlear nu 4Sh trochlear nu shell region 5TT motor trigem, tensor tymp 7n facial nerve Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CEnt caudomed entothinal cx CLi caudal linear nu raphe DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral ECIC external cx inferior coll Ect ectorhinal cortex ILL intermed nu lat lemniscus InG intermed gray layer SC InWh intermediate white layer SC lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu mRt mesenceph reticular form MVPO medioventral periolivary nu Op optic nerve layer sup coll PaS parasubiculum PBG parabigeminal nu PlPAG pleoglial PAG PLV perilemniscal nu, ventral PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PrCnF precuneiform area PRh perirhinal cx PTg pedunculopontine tegmental ptgpal pterygopalatine n RR retrorubral nu RRF/A8 retrorubral/A8 dopamine rs rubrospinal tract RSD retrosplenial dysgranular cx RtTg reticulotegmental nu pons s5 sensory root trigem n SubB subbrachial nu SuG superficial gray sup coll TempP temporal bone, petrous tfp transverse fibers pons ts tectospinal tr tth trigeminothalamic tr V1 primary visual cortex V2L 2ary visual cx, lat area VeGn vestibular n ganglion VLL ventral nu lat lemniscus VLPAG ventlat periaqueductal gray xscp decussation sup cereb ped Zo zona layer sup coll

Figure 152 P6 #49 7.23 mm

Zo SuG Op InG V1

V2L

InWh

PRh

sf

DpG

RSD

DMPAG PaS

PlPAG

DpWh DLPAG

CEnt

bic

ECIC

Aq

BIC

LPAG PrCnF

DRD

DRL PBG

isRt

MiTg

PDR

RRF/A8 RR

7n

VeGn

TempP

ptgpal

7n

s5

ATg

MPL

Rbd

vsc

PMnR

ts

PnO 5TT Pr5 m5 A7

8vn

DRI CLi xscp

SPTg

VLL mcp

4N mlf

PTg

ILL

DRV

MnR

rs

sp5

RtTg ll VLL

Pn CAT

ml lfp

MVPO

tfp bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4N trochlear nu 5TT motor trigem, tensor tymp 7n facial nerve 8vn vestibular root of 8th nerve A7 A7 noradrenaline cells Aq aqueduct ATg anterior tegmental nu bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CAT nu central acoustic tr CEnt caudomed entothinal cx CLi caudal linear nu raphe DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRI dorsal raphe, interfascicular DRL dorsal raphe nu, lateral DRV dorsal raphe nu, ventral ECIC external cx inferior coll ILL intermed nu lat lemniscus InG intermed gray layer SC InWh intermediate white layer SC isRt isthmic reticular form lfp longitudinal fasciculus pons ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu Op optic nerve layer sup coll PaS parasubiculum PBG parabigeminal nu PDR posterodors raphe nu PlPAG pleoglial PAG PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PrCnF precuneiform area PRh perirhinal cx PTg pedunculopontine tegmental ptgpal pterygopalatine n Rbd rhabdoid nu RR retrorubral nu RRF/A8 retrorubral/A8 dopamine rs rubrospinal tract RSD retrosplenial dysgranular cx RtTg reticulotegmental nu pons s5 sensory root trigem n sf secondary fissure sp5 spinal trigem tract SPTg subpeduncular tegmental nu SuG superficial gray sup coll TempP temporal bone, petrous tfp transverse fibers pons ts tectospinal tr V1 primary visual cortex V2L 2ary visual cx, lat area VeGn vestibular n ganglion VLL ventral nu lat lemniscus vsc ventral spinocerebellar tr xscp decussation sup cereb ped Zo zona layer sup coll

Figure 153 P6 #50 7.35 mm Zo SuG Op InG

InWh DpG DMPAG DLPAG DpWh BIC

Aq

ECIC

LPAG

bic PrCnF

PDR 4Sh

DRV

4N

isRt RR

DRI

Pa4

DLL

EGL

DRD

DRL

PBG MiTg

mlf

PTg

xscp

TrLL

SPTg

ILL

ATg Rbd

mcp

MPL

vsc KF

PMnR ts

A7 VCA VeGn

s5

Pr5

MnR

PnO

5TT P5 m5 rs tz 7n

RtTg

ll Pn

VLL CAT

vsc

Tz

ScTy Corti

MVPO

ml py

tz bas

ScVe

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

CD

0

0.2

0.4

0.6

0.8

1.0 mm

4N trochlear nu 4Sh trochlear nu shell region 5TT motor trigem, tensor tymp 7n facial nerve A7 A7 noradrenaline cells Aq aqueduct ATg anterior tegmental nu bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CAT nu central acoustic tr CD cochlear duct Corti organ of Corti DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRI dorsal raphe, interfascicular DRL dorsal raphe nu, lateral DRV dorsal raphe nu, ventral ECIC external cx inferior coll EGL external granular layer Cb ILL intermed nu lat lemniscus InG intermed gray layer SC InWh intermediate white layer SC isRt isthmic reticular form KF Kˆlliker-Fuse nu ll lateral lemniscus LPAG lat periaqueductal gray m5 motor root trigeminal nerve mcp middle cerebellar peduncle MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MPL medial paralemniscial nu MVPO medioventral periolivary nu Op optic nerve layer sup coll P5 peritrigeminal zone Pa4 paratrochlear nu PBG parabigeminal nu PDR posterodors raphe nu PMnR paramedian raphe nu Pn pontine nuclei PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PrCnF precuneiform area PTg pedunculopontine tegmental py pyramidal tr Rbd rhabdoid nu RR retrorubral nu rs rubrospinal tract RtTg reticulotegmental nu pons s5 sensory root trigem n ScTy scala tympani ScVe scala vestibuli SPTg subpeduncular tegmental nu SuG superficial gray sup coll TrLL triangular nu, lat lemniscus ts tectospinal tr Tz nu trapezoid body tz trapezoid body VCA ventral cochlear nu, ant VeGn vestibular n ganglion VLL ventral nu lat lemniscus vsc ventral spinocerebellar tr xscp decussation sup cereb ped Zo zona layer sup coll

Figure 154 P6 #51 7.47 mm Zo SuG Op InG InWh DpG DMPAG DpWh

DLPAG

bic BIC

ECIC Aq

LPAG PrCnF

DRD

MiTg

CnF

PBG

DRL DRV

DLL

ll

PDR TrLL MPL

PFl GrCb

EGL

mlf SPTg

mcp

KF

SubCD

ts

PnO 5N

VCA VeGn

8vn

s5

PMnR

P5

Pr5

MnR PnC

5TT

RtTg

tz 7n

rs

TempP vsc 8cn

DRI

VTg

vsc

Pk

MoCb

Pa4

scp

PTg

ILL

A5

MSO

LVPO

RIP CAT

ScTy

MVPO

Corti

ml

Tz py

bas

CGn CD ScVe

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

5N motor trigeminal nu 5TT motor trigem, tensor tymp 7n facial nerve 8cn cochlear root 8th nerve 8vn vestibular root of 8th nerve A5 A5 noradrenaline cells Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CAT nu central acoustic tr CD cochlear duct CGn cochlear (spiral) ganglion CnF cuneiform nu Corti organ of Corti DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRI dorsal raphe, interfascicular DRL dorsal raphe nu, lateral DRV dorsal raphe nu, ventral ECIC external cx inferior coll EGL external granular layer Cb GrCb granule cell layer cb ILL intermed nu lat lemniscus InG intermed gray layer SC InWh intermediate white layer SC KF Kˆlliker-Fuse nu ll lateral lemniscus LPAG lat periaqueductal gray LVPO lateroventral periolivary nu mcp middle cerebellar peduncle MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MoCb molecular layer Cb MPL medial paralemniscial nu MSO medial superior olive MVPO medioventral periolivary nu Op optic nerve layer sup coll P5 peritrigeminal zone Pa4 paratrochlear nu PBG parabigeminal nu PDR posterodors raphe nu PFl paraflocculus Pk Purkinje cell layer Cb PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Pr5 principal sensory trigem nu PrCnF precuneiform area PTg pedunculopontine tegmental py pyramidal tr RIP raphe interpositus nu rs rubrospinal tract RtTg reticulotegmental nu pons s5 sensory root trigem n scp superior Cb peduncle ScTy scala tympani ScVe scala vestibuli SPTg subpeduncular tegmental nu SubCD subcoeruleus nu, dorsal SuG superficial gray sup coll TempP temporal bone, petrous TrLL triangular nu, lat lemniscus ts tectospinal tr Tz nu trapezoid body tz trapezoid body VCA ventral cochlear nu, ant VeGn vestibular n ganglion vsc ventral spinocerebellar tr VTg vent tegmental nu Zo zona layer sup coll

Figure 155 P6 #52 7.59 mm Zo SuG Op InG

InWh DpG DpWh

bic

DMPAG DLPAG

BIC ECIC

Aq

Me5 LPAG

PBG PrCnF MiTg

DRL

DRD

LDTg

DRV

CnF Crus2 GrCb EGL

psf ll

PTg

DLL

scp

Pk

MoCb plf

Sim

mlf LDTgV

mcp

DRI

SPTg

vsc

VTg

KF SubCD

PFl

Su5 PnO

Pr5DM P5 5N

VCA

A7

ts PMnR

DMTg MnR

tz 8vn

VeGn

Pr5VL sp5

SubCV PnC

rs

7n vsc

8cn

RtTg

m5 5TT A5

MSO RIP

LSO SPO LVPO

ml

Tz

MVPO

py

tz

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

bas

1.0 mm

5N motor trigeminal nu 5TT motor trigem, tensor tymp 7n facial nerve 8cn cochlear root 8th nerve 8vn vestibular root of 8th nerve A5 A5 noradrenaline cells A7 A7 noradrenaline cells Aq aqueduct bas basilar artery BIC nu brachium inf colliculus bic brachium inf colliculus CnF cuneiform nu Crus2 crus 2 ansiform lobule DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRI dorsal raphe, interfascicular DRL dorsal raphe nu, lateral DRV dorsal raphe nu, ventral ECIC external cx inferior coll EGL external granular layer Cb GrCb granule cell layer cb InG intermed gray layer SC InWh intermediate white layer SC KF Kˆlliker-Fuse nu LDTg laterodor tegmental nu LDTgV laterodor tegmental nu, vent ll lateral lemniscus LPAG lat periaqueductal gray LSO lat superior olive LVPO lateroventral periolivary nu m5 motor root trigeminal nerve mcp middle cerebellar peduncle Me5 mesencephalic trigem nu MiTg microcell tegmental nu ml medial lemniscus mlf med longitudinal fasciculus MnR median raphe nu MoCb molecular layer Cb MSO medial superior olive MVPO medioventral periolivary nu Op optic nerve layer sup coll P5 peritrigeminal zone PBG parabigeminal nu PFl paraflocculus Pk Purkinje cell layer Cb plf posterolateral fissure PMnR paramedian raphe nu PnC pontine reticular nu, caudal PnO pontine reticular nu, oral Pr5DM principal sens 5, dorsomed Pr5VL principal sens 5, ventrolat PrCnF precuneiform area psf post superior fissure PTg pedunculopontine tegmental py pyramidal tr RIP raphe interpositus nu rs rubrospinal tract RtTg reticulotegmental nu pons scp superior Cb peduncle Sim simple lobule sp5 spinal trigem tract SPO superior paraolivary nu SPTg subpeduncular tegmental nu Su5 supratrigeminal nu SubCD subcoeruleus nu, dorsal SubCV subcoeruleus nu, ventral SuG superficial gray sup coll ts tectospinal tr Tz nu trapezoid body tz trapezoid body VCA ventral cochlear nu, ant VeGn vestibular n ganglion vsc ventral spinocerebellar tr VTg vent tegmental nu Zo zona layer sup coll

Figure 156 P6 #53 7.71 mm

Zo SuG Op InG InWh DpG DpWh ECIC

bic

ne

LPAG

ll Crus1 Sag

Aq

CnF

ll

VLPAG

pfs GrCb pfs Pk EGL MoCb Sim

DMPAG DLPAG

DLL

vsc LPBE

DRD

LPBS

LDTg

LPBC scp MPB PTg

DRV

LDTgV mlf

plf

cbw

SPTg

KF

PFl

VTg

Su5

PnR

Pr5DM

SubCD 5N

DMTg

5ADi

RtTgP

VCA m5 8cn

RtTg SubCV

Pr5VL sp5

PnC RIP

A5 tz

rs

7n

PnV RMg

LSO

vsc

SPO

LVPO

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

MSO

DPO

0

MVPO

Tz

0.2

0.6

0.4

ml RPa py bas

0.8

1.0 mm

5ADi motor trigem, ant digastric 5N motor trigeminal nu 7n facial nerve 8cn cochlear root 8th nerve A5 A5 noradrenaline cells Aq aqueduct bas basilar artery bic brachium inf colliculus cbw cerebellar white matter CnF cuneiform nu Crus1 crus 1 ansiform lobule DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DPO dorsal periolivary region DpWh deep white superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral ECIC external cx inferior coll EGL external granular layer Cb GrCb granule cell layer cb InG intermed gray layer SC InWh intermediate white layer SC KF Kˆlliker-Fuse nu LDTg laterodor tegmental nu LDTgV laterodor tegmental nu, vent ll lateral lemniscus LPAG lat periaqueductal gray LPBC lat parabrachial nu, central LPBE lat parabrachial nu, external LPBS lat parabrachial nu, sup LSO lat superior olive LVPO lateroventral periolivary nu m5 motor root trigeminal nerve ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb MPB medial parabrachial nu MSO medial superior olive MVPO medioventral periolivary nu ne neuroepithelium Op optic nerve layer sup coll PFl paraflocculus pfs parafloccular sulcus Pk Purkinje cell layer Cb plf posterolateral fissure PnC pontine reticular nu, caudal PnR pontine raphe nu PnV pontine retic nu, ventral Pr5DM principal sens 5, dorsomed Pr5VL principal sens 5, ventrolat PTg pedunculopontine tegmental py pyramidal tr RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract RtTg reticulotegmental nu pons RtTgP reticuloteg nu, pericentral Sag sagulum nu scp superior Cb peduncle Sim simple lobule sp5 spinal trigem tract SPO superior paraolivary nu SPTg subpeduncular tegmental nu Su5 supratrigeminal nu SubCD subcoeruleus nu, dorsal SubCV subcoeruleus nu, ventral SuG superficial gray sup coll Tz nu trapezoid body tz trapezoid body VCA ventral cochlear nu, ant VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr VTg vent tegmental nu Zo zona layer sup coll

Figure 157 P6 #54 7.83 mm

Zo SuG Op InG InWh DpG ECIC

DMPAG DLPAG CIC

bic

Aq

LPAG Crus1

CnF psf

pfs

RL DLL LPBS LPBC scp vsc PTg MPB

Crus1 EGL

PFl

VLPAG

Sim

DRD LDTg Bar

DRV DTgP

LPBE

cbw

LDTgV

VTg

KF plf

Su5

Fl

SubCA

Pr5DM

LR4V

5N

m5

PnR

P5

DMTg RtTgL

SubCD

RtTg

VCA 5ADi 6RB

sp5 Pr5VL

PnC IRt

7n I8 VeGn

RIP

tz

8cn vsc CGn

rs A5

LSO

MSO

PnV SPO Tz

LVPO

0

0.2

0.4

0.6

RMg ml RPa

py

MVPO

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

mlf

0.8

bas

1.0 mm

5ADi motor trigem, ant digastric 5N motor trigeminal nu 6RB abducens, retractor bulbi 7n facial nerve 8cn cochlear root 8th nerve A5 A5 noradrenaline cells Aq aqueduct Bar Barrington’s nu bas basilar artery bic brachium inf colliculus cbw cerebellar white matter CGn cochlear (spiral) ganglion CIC central nu inf colliculus CnF cuneiform nu Crus1 crus 1 ansiform lobule DLL dorsal nu lateral lemniscus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DRD dorsal raphe nu, dorsal DRV dorsal raphe nu, ventral DTgP dors tegmental nu, pericent ECIC external cx inferior coll EGL external granular layer Cb Fl flocculus I8 interstitial nu 8th nerve InG intermed gray layer SC InWh intermediate white layer SC IRt intermed reticular nu KF Kˆlliker-Fuse nu LDTg laterodor tegmental nu LDTgV laterodor tegmental nu, vent LPAG lat periaqueductal gray LPBC lat parabrachial nu, central LPBE lat parabrachial nu, external LPBS lat parabrachial nu, sup LR4V lat recess 4th ventricle LSO lat superior olive LVPO lateroventral periolivary nu m5 motor root trigeminal nerve ml medial lemniscus mlf med longitudinal fasciculus MPB medial parabrachial nu MSO medial superior olive MVPO medioventral periolivary nu Op optic nerve layer sup coll P5 peritrigeminal zone PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure PnC pontine reticular nu, caudal PnR pontine raphe nu PnV pontine retic nu, ventral Pr5DM principal sens 5, dorsomed Pr5VL principal sens 5, ventrolat psf post superior fissure PTg pedunculopontine tegmental py pyramidal tr RIP raphe interpositus nu RL retrolemniscal nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract RtTg reticulotegmental nu pons RtTgL reticulotegmental pons, lat scp superior Cb peduncle Sim simple lobule sp5 spinal trigem tract SPO superior paraolivary nu Su5 supratrigeminal nu SubCA subcoeruleus nu, alpha SubCD subcoeruleus nu, dorsal SuG superficial gray sup coll Tz nu trapezoid body tz trapezoid body VCA ventral cochlear nu, ant VeGn vestibular n ganglion VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr VTg vent tegmental nu Zo zona layer sup coll

Figure 158 P6 #55 7.95 mm

Zo SuG Op InG InWh DpG DMPAG

ECIC

DLPAG

CIC EGL

Crus1 LPAG plf

ne CnF

Crus1 pfs

VLPAG

RL

Sim

DRC LPB

vsc cbw

LDTg

LPBE

PFl

KF

Pr5DM LR4V

SubCA EVe

CGB

5Tr

VCA

SubCD

4V DMTg

PCRtA

RIP

Pr5VL 8cn

7SH tz

sp5

mlf

IRt

7n

I8

rs

SuS A5

PnC

LPGi GrA

P7 7N

vsc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

DTgC

MPBE Su5

Fl

DTgP

LC Bar

scp

plf

2Cb

0

0.2

RMg ml RPa py bas

0.4

0.6

0.8

1.0 mm

2Cb 2nd cerebellar lobule 4V 4th ventricle 5Tr trigem transition zone 7N facial nu 7n facial nerve 7SH facial motor nu, stylohyoid 8cn cochlear root 8th nerve A5 A5 noradrenaline cells Bar Barrington’s nu bas basilar artery cbw cerebellar white matter CGB central gray, beta part CIC central nu inf colliculus CnF cuneiform nu Crus1 crus 1 ansiform lobule DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DMTg dorsomed tegmental area DpG deep gray superior coll DRC dorsal raphe nu, caudal DTgC dors tegmental nu, central DTgP dors tegmental nu, pericent ECIC external cx inferior coll EGL external granular layer Cb EVe nu origin efferents ve n Fl flocculus GrA granule cell, acc olf bulb I8 interstitial nu 8th nerve InG intermed gray layer SC InWh intermediate white layer SC IRt intermed reticular nu KF Kˆlliker-Fuse nu LC locus coeruleus LDTg laterodor tegmental nu LPAG lat periaqueductal gray LPB lateral parabrachial nu LPBE lat parabrachial nu, external LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle ml medial lemniscus mlf med longitudinal fasciculus MPBE med parabrachial nu ext ne neuroepithelium Op optic nerve layer sup coll P7 perifacial zone PCRtA parvicell reticular nu, alpha PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure PnC pontine reticular nu, caudal Pr5DM principal sens 5, dorsomed Pr5VL principal sens 5, ventrolat py pyramidal tr RIP raphe interpositus nu RL retrolemniscal nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract scp superior Cb peduncle Sim simple lobule sp5 spinal trigem tract Su5 supratrigeminal nu SubCA subcoeruleus nu, alpha SubCD subcoeruleus nu, dorsal SuG superficial gray sup coll SuS superior salivatory nu tz trapezoid body VCA ventral cochlear nu, ant VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr Zo zona layer sup coll

Figure 159 P6 #56 8.07 mm

Zo SuG Op DCIC Com ECIC DMPAG

CIC

DLPAG

Crus1

LPAG

psf Crus1

EGL VLPAG

CnF

2Cb

icf pfs

Crus2

Sim

cbw

LPB scp Lat

MPB icf

DRC

LDTg

LPBE

DTgP DTgC

LC Bar

KF

PFl GrC plf

Fl LR4V

DC 8vn

CGB

MVePC SuVe

CGO

MVeMC 5Tr

VCP

sp5

7n

PCRtA

8n

SuS

SGe EVe CGG CGA

4V 6N ocb mlf

IRt

Pr5

Gi

7SH

8cn

RIP

SuS

tz

7DL 7DI 7DM RMg 7L GiA 7VI 7VM LPGi vsc RPa ml py 6n rs

bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2Cb 2nd cerebellar lobule 4V 4th ventricle 5Tr trigem transition zone 6N abducens nu 6n root of abducens nerve 7DI facial nu, dors intermedial 7DL facial nu, dorsolateral 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7n facial nerve 7SH facial motor nu, stylohyoid 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8cn cochlear root 8th nerve 8n vestibulocochlear nerve 8vn vestibular root of 8th nerve Bar Barrington’s nu bas basilar artery cbw cerebellar white matter CGA central gray, alpha part CGB central gray, beta part CGG central gray, gamma part CGO central gray, nu O CIC central nu inf colliculus CnF cuneiform nu Com commissural nu inf colliculus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DC dorsal cochlear nu DCIC dors cx inf colliculus DLPAG dorsolat periaqueductal gray DMPAG dorsomed periaqueductl gray DRC dorsal raphe nu, caudal DTgC dors tegmental nu, central DTgP dors tegmental nu, pericent ECIC external cx inferior coll EGL external granular layer Cb EVe nu origin efferents ve n Fl flocculus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha GrC granule cell, cochlear nu icf intercrural fissure IRt intermed reticular nu KF Kˆlliker-Fuse nu Lat lateral (dentate) Cb nu LC locus coeruleus LDTg laterodor tegmental nu LPAG lat periaqueductal gray LPB lateral parabrachial nu LPBE lat parabrachial nu, external LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle ml medial lemniscus mlf med longitudinal fasciculus MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul ocb olivocochlear bundle Op optic nerve layer sup coll PCRtA parvicell reticular nu, alpha PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure Pr5 principal sensory trigem nu psf post superior fissure py pyramidal tr RIP raphe interpositus nu RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract scp superior Cb peduncle SGe supragenual nu Sim simple lobule sp5 spinal trigem tract SuG superficial gray sup coll SuS superior salivatory nu SuVe superior vestibular nu tz trapezoid body VCP vent cochlear nu, posterior VLPAG ventlat periaqueductal gray vsc ventral spinocerebellar tr Zo zona layer sup coll

Figure 160 P6 #57 8.19 mm

Zo SuG DCIC Com ECIC CIC DMPAG LPAG ReIC

Crus1

Crus1

psf 3Cb

icf

CnF Sim Crus2

cbw

pfs

LPBI

vsc LPB

2Cb

EGL

4V

scp Lat icp

LPBE

MPB Me5 LC

LDTg DTgP DRC Bar Sph

PFl

SuVe

GrC Fl

plf LR4V

DC

PDTg MVePC 8vn

VeMC

VCCap

EVe SGe Pr CGA g7 6N mlf CGG DPGi

sp5 DCMo VCP

Pr5

tz

rs vsc

PCRtA

IRt

7SH P7 7DL 7DI 7DM 7L 7VI 7VM

4V

Gi GiA LPGi

RMg ml RPa py bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2Cb 2nd cerebellar lobule 3Cb 3rd cerebellar lobule 4V 4th ventricle 6N abducens nu 7DI facial nu, dors intermedial 7DL facial nu, dorsolateral 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7SH facial motor nu, stylohyoid 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8vn vestibular root of 8th nerve Bar Barrington’s nu bas basilar artery cbw cerebellar white matter CGA central gray, alpha part CGG central gray, gamma part CIC central nu inf colliculus CnF cuneiform nu Com commissural nu inf colliculus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DC dorsal cochlear nu DCIC dors cx inf colliculus DCMo dors cochlear nu, molecular DMPAG dorsomed periaqueductl gray DPGi dors paragigantocellular nu DRC dorsal raphe nu, caudal DTgP dors tegmental nu, pericent ECIC external cx inferior coll EGL external granular layer Cb EVe nu origin efferents ve n Fl flocculus g7 genu facial nerve Gi gigantocellular reticular nu GiA gigantocellular retic, alpha GrC granule cell, cochlear nu icf intercrural fissure icp inf cerebellar peduncle IRt intermed reticular nu Lat lateral (dentate) Cb nu LC locus coeruleus LDTg laterodor tegmental nu LPAG lat periaqueductal gray LPB lateral parabrachial nu LPBE lat parabrachial nu, external LPBI lat parabrachial nu, internal LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle Me5 mesencephalic trigem nu ml medial lemniscus mlf med longitudinal fasciculus MPB medial parabrachial nu MVeMC med vestib nu, magnocellul MVePC med vestib nu, parvicellul P7 perifacial zone PCRtA parvicell reticular nu, alpha PDTg posterodors tegmental nu PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure Pr prepositus nu Pr5 principal sensory trigem nu psf post superior fissure py pyramidal tr ReIC recess inferior coll RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract scp superior Cb peduncle SGe supragenual nu Sim simple lobule sp5 spinal trigem tract Sph sphenoid nu SuG superficial gray sup coll SuVe superior vestibular nu tz trapezoid body VCCap vent cochlear nu, capsular VCP vent cochlear nu, posterior vsc ventral spinocerebellar tr Zo zona layer sup coll

Figure 161 P6 #58 8.31 mm

DCIC EGL

Com

ECIC Crus1

CIC

DMPAG ReIC DMPAG

psf

Crus1

pcuf

4Cb

EGL

icf Sim

MoCb Crus2

Pk

cbw

vsc

pfs

IntA

LatPC

MPB VeCb Me5 LC SuVe

plf

LVe

VCCap

LR4V

PDTg MVePC

SpVe

DCDp

MVeMC

DMSp5 5Sol

VCP 8n Sp5O tz

4V

Pr

X

DCMo GrC

Sph DRC

icp Fl

4V

DTgP

LDTg

Y

GrC

PFl

LPBI

LPB

scp

Lat GrC

DCFu

2/3Cb

PCRtA

sp5 Sp5I rs vsc

vesp

DPGi

P7

ts

7SH

Gi

7DL 7DI 7L

mlf

IRt

7DM 7VI

7VM

GiA RMg

LPGi

ml

RPa C1

py bas

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

2/3Cb 2nd/3rd cerebellarlobules 4Cb 4th cerebellar lobule 4V 4th ventricle 5Sol trigeminal-solitary trans 7DI facial nu, dors intermedial 7DL facial nu, dorsolateral 7DM facial nu, dorsomedial 7L facial nu, lateral subnu 7SH facial motor nu, stylohyoid 7VI 7 nu, ventral intermediate 7VM facial nu, ventromedial 8n vestibulocochlear nerve bas basilar artery C1 C1 adrenaline cells cbw cerebellar white matter CIC central nu inf colliculus Com commissural nu inf colliculus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DCDp dors cochlear nu, deep core DCFu dors cochlear nu, fusiform DCIC dors cx inf colliculus DCMo dors cochlear nu, molecular DMPAG dorsomed periaqueductl gray DMSp5 dorsomed spinal trigem nu DPGi dors paragigantocellular nu DRC dorsal raphe nu, caudal DTgP dors tegmental nu, pericent ECIC external cx inferior coll EGL external granular layer Cb Fl flocculus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha GrC granule cell, cochlear nu icf intercrural fissure icp inf cerebellar peduncle IntA interposed cerebellar nu, ant IRt intermed reticular nu Lat lateral (dentate) Cb nu LatPC lat Cb nu, parvicell LC locus coeruleus LDTg laterodor tegmental nu LPB lateral parabrachial nu LPBI lat parabrachial nu, internal LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu Me5 mesencephalic trigem nu ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb MPB medial parabrachial nu MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul P7 perifacial zone PCRtA parvicell reticular nu, alpha pcuf preculminate fissure PDTg posterodors tegmental nu PFl paraflocculus pfs parafloccular sulcus Pk Purkinje cell layer Cb plf posterolateral fissure Pr prepositus nu psf post superior fissure py pyramidal tr ReIC recess inferior coll RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract scp superior Cb peduncle Sim simple lobule sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sp5O spinal trigeml nu, oral Sph sphenoid nu SpVe spinal vestibular nu SuVe superior vestibular nu ts tectospinal tr tz trapezoid body VCCap vent cochlear nu, capsular VCP vent cochlear nu, posterior VeCb vestibulocerebellar nu vesp vestibulospinal tr vsc ventral spinocerebellar tr X nu X Y nu Y

Figure 162 P6 #59 8.43 mm

DCIC Com

ECIC CIC

Crus1 psf

Crus1

4/5Cb

icf Sim prf

EGL

Crus2

MoCb

cbw Pk

IntDL pfs

Lat

chp 4V

LatPC

cbw

Y

LVe

GrC

PFl Fl plf

DCDp

LR4V DCFu GrC VCCap DCMo

VCP

MVePC MVeMC

SpVe

icp

Pr

X SolRL sol SolIM DMSp5 5Sol

8cn Sp5O

sp5

rs vsc

SolM

IS DPGi mlf

IRt

PCRt 7SH

tz Sp5I

Gi

ts

P7 7N

GiA LPGi

JugF

C1

S9Gn

RMg

ml

PPy

py

RPa bas

BOcc

10Gn

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

SMV

VeCb LC

scp

2/3Cb

GrCb

Med

IntA

0

0.2

0.4

0.6

0.8

1.0 mm

2/3Cb 2nd/3rd cerebellarlobules 4/5Cb 4th/5th cerebellar lobules 4V 4th ventricle 5Sol trigeminal-solitary trans 7N facial nu 7SH facial motor nu, stylohyoid 8cn cochlear root 8th nerve 10Gn vagus nerve ganglion bas basilar artery BOcc basioccipital bone C1 C1 adrenaline cells cbw cerebellar white matter chp choroid plexus CIC central nu inf colliculus Com commissural nu inf colliculus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DCDp dors cochlear nu, deep core DCFu dors cochlear nu, fusiform DCIC dors cx inf colliculus DCMo dors cochlear nu, molecular DMSp5 dorsomed spinal trigem nu DPGi dors paragigantocellular nu ECIC external cx inferior coll EGL external granular layer Cb Fl flocculus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha GrC granule cell, cochlear nu GrCb granule cell layer cb icf intercrural fissure icp inf cerebellar peduncle IntA interposed cerebellar nu, ant IntDL interposed, dorsolat hump IRt intermed reticular nu IS inferior salivatory nu JugF jugular foramen Lat lateral (dentate) Cb nu LatPC lat Cb nu, parvicell LC locus coeruleus LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu Med medial cerebellar nu ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul P7 perifacial zone PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus Pk Purkinje cell layer Cb plf posterolateral fissure PPy parapyramidal nu Pr prepositus nu prf primary fissure psf post superior fissure py pyramidal tr RMg raphe magnus nu RPa raphe pallidus nu rs rubrospinal tract S9Gn superior ganglion 9n scp superior Cb peduncle Sim simple lobule SMV superior medullary velum sol solitary tract SolIM nu sol tract, intermediate SolM nu sol tract, medial SolRL nu sol tract, rostrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sp5O spinal trigeml nu, oral SpVe spinal vestibular nu ts tectospinal tr tz trapezoid body VCCap vent cochlear nu, capsular VCP vent cochlear nu, posterior VeCb vestibulocerebellar nu vsc ventral spinocerebellar tr X nu X Y nu Y

Figure 163 P6 #60 8.55 mm

DCIC ECIC

Crus1

CIC

psf Crus1 prf

icf Sim

4/5Cb

Crus2

GrCb Pk

PM

IntP pfs

Lat

4V

Y

DCFu DCDp icp

LR4V

GrC

X

GrC

sp5 Sp5O

VCPO

rs

MVeMC

SolRL sol

PCRt

Gi

7N

ROb

Bo GiA RMg RPa ml

RVL C1 LPGi PPy

S9Gn 9/10/11n

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

DPGi mlf

ts

7SH

JugF

10Gn

IS

IRt

vsc

I9Gn

Pr

SolDL

SolIM SolM 5Sol

Sp5I

dsc/oc

MVePC

SpVe

DMSp5

TempP

1Cb

VeCb LVe

DCMo

plf Fl

Med

scp

LatPC

PFl

EGL 2/3Cb cbw

IntA

IntDL

py

bas

BOcc

0

0.2

0.4

0.6

0.8

1.0 mm

1Cb 1st cerebellar lobule 2/3Cb 2nd/3rd cerebellarlobules 4/5Cb 4th/5th cerebellar lobules 4V 4th ventricle 5Sol trigeminal-solitary trans 7N facial nu 7SH facial motor nu, stylohyoid 9/10/11n 9n, 10n, and 11n 10Gn vagus nerve ganglion bas basilar artery Bo Botzinger complex BOcc basioccipital bone C1 C1 adrenaline cells cbw cerebellar white matter CIC central nu inf colliculus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DCDp dors cochlear nu, deep core DCFu dors cochlear nu, fusiform DCIC dors cx inf colliculus DCMo dors cochlear nu, molecular DMSp5 dorsomed spinal trigem nu DPGi dors paragigantocellular nu dsc/oc dors spino / olivocereb tr ECIC external cx inferior coll EGL external granular layer Cb Fl flocculus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha GrC granule cell, cochlear nu GrCb granule cell layer cb I9Gn inferior ganglion 9n icf intercrural fissure icp inf cerebellar peduncle IntA interposed cerebellar nu, ant IntDL interposed, dorsolat hump IntP interposed cerebellar nu, post IRt intermed reticular nu IS inferior salivatory nu JugF jugular foramen Lat lateral (dentate) Cb nu LatPC lat Cb nu, parvicell LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu Med medial cerebellar nu ml medial lemniscus mlf med longitudinal fasciculus MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus Pk Purkinje cell layer Cb plf posterolateral fissure PM paramedian lobule PPy parapyramidal nu Pr prepositus nu prf primary fissure psf post superior fissure py pyramidal tr RMg raphe magnus nu ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract RVL rostroventrolat retic nu S9Gn superior ganglion 9n scp superior Cb peduncle Sim simple lobule sol solitary tract SolDL sol nu, dorsolateral SolIM nu sol tract, intermediate SolM nu sol tract, medial SolRL nu sol tract, rostrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar Sp5O spinal trigeml nu, oral SpVe spinal vestibular nu TempP temporal bone, petrous ts tectospinal tr VCPO vent cochlear, post, octopus VeCb vestibulocerebellar nu vsc ventral spinocerebellar tr X nu X Y nu Y

Figure 164 P6 #61 8.67mm

DCIC ECIC Crus1 pfs

CIC

Crus1 icf

5Cb Sim GrCb

prf

Crus2 apmf PM

IntDL

IntA

pfs

scp

Lat LatPC PFl

VeCb MedL

10Cb

LVe DCFu DCDp icp

Fl

VCP

X

SolVL

Sp5I

MVeMC

SpVe

sp5 DMSp5 5Sol

sol

Pr

IS

SolV SolIM

4V

MVePC

SolDM

DPGi

SolM

Gi

P7

rs

mlf

IRt

PCRt

dsc/oc

ts

ROb RMg

Bo GiA

vsc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

EGL

DCMo

plf

LR4V

cbw

Med

IntP

LPGi C1

0

0.2

RPa IOD ml IOM py bas

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Cb 5th cerebellar lobule 5Sol trigeminal-solitary trans 10Cb 10th cerebellar lobule apmf ansoparamedian fissure bas basilar artery Bo Botzinger complex C1 C1 adrenaline cells cbw cerebellar white matter CIC central nu inf colliculus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DCDp dors cochlear nu, deep core DCFu dors cochlear nu, fusiform DCIC dors cx inf colliculus DCMo dors cochlear nu, molecular DMSp5 dorsomed spinal trigem nu DPGi dors paragigantocellular nu dsc/oc dors spino / olivocereb tr ECIC external cx inferior coll EGL external granular layer Cb Fl flocculus Gi gigantocellular reticular nu GiA gigantocellular retic, alpha GrCb granule cell layer cb icf intercrural fissure icp inf cerebellar peduncle IntA interposed cerebellar nu, ant IntDL interposed, dorsolat hump IntP interposed cerebellar nu, post IOD inf olive, dorsal nu IOM inf olive, med nu IRt intermed reticular nu IS inferior salivatory nu Lat lateral (dentate) Cb nu LatPC lat Cb nu, parvicell LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle LVe lateral vestibular nu Med medial cerebellar nu MedL medial Cb nu, lateral ml medial lemniscus mlf med longitudinal fasciculus MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul P7 perifacial zone PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure PM paramedian lobule Pr prepositus nu prf primary fissure py pyramidal tr RMg raphe magnus nu ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract scp superior Cb peduncle Sim simple lobule sol solitary tract SolDM nu sol tract, dorsomed SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu ts tectospinal tr VCP vent cochlear nu, posterior VeCb vestibulocerebellar nu vsc ventral spinocerebellar tr X nu X

Figure 165 P6 #62 8.79 mm

ECIC Crus1

6Cb

psf

Crus1

prf

icf

Sim

5Cb

EGL

Crus2

cbw

apmf

EGL

MedDL Med

PM IntP

MedL

pfs

IntPPC

10Cb

PFl Fl plf

LR4V

DCMo icp

X

MVeMC

sol

FVe

SolDM Mx SolVL SolV SolM SolIM 5Sol

DMSp5

LR4V

Gi

IRt

Sp5I

ts ROb

AmbC Bo vsc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

Ro DPGi mlf

PCRt

rs

Pr

10n 12N

sp5

dsc/oc

4V

MVePC

SpVe

PMn GiV LPGi C1 RVL IOD

0

0.2

0.4

RPa IOPr ml bas py IOM

0.6

0.8

1.0 mm

4V 4th ventricle 5Cb 5th cerebellar lobule 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 10Cb 10th cerebellar lobule 10n vagus nerve 12N hypoglossal nu AmbC ambiguus nu, compact part apmf ansoparamedian fissure bas basilar artery Bo Botzinger complex C1 C1 adrenaline cells cbw cerebellar white matter Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DCMo dors cochlear nu, molecular DMSp5 dorsomed spinal trigem nu DPGi dors paragigantocellular nu dsc/oc dors spino / olivocereb tr ECIC external cx inferior coll EGL external granular layer Cb Fl flocculus FVe F cell group vestib Gi gigantocellular reticular nu GiV gigantocellular retic, vent icf intercrural fissure icp inf cerebellar peduncle IntP interposed cerebellar nu, post IntPPC interposed, post parvicellular IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle Med medial cerebellar nu MedDL medial Cb, dorsolat protub MedL medial Cb nu, lateral ml medial lemniscus mlf med longitudinal fasciculus MVeMC med vestib nu, magnocell MVePC med vestib nu, parvicellul Mx matrix region medulla PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus plf posterolateral fissure PM paramedian lobule PMn paramedian reticular nu Pr prepositus nu prf primary fissure psf post superior fissure py pyramidal tr Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract RVL rostroventrolat retic nu Sim simple lobule sol solitary tract SolDM nu sol tract, dorsomed SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu ts tectospinal tr vsc ventral spinocerebellar tr X nu X

Figure 166 P6 #63 8.91 mm

EGL ECIC

MoCb

6Cb

psf Crus1

GrCb Sim

Crus1 icf cbw

Pk

5Cb

Crus2 7Cb MedDL

apmf

Med PM

GrCb

IntP

10Cb pfs PFl plf

Fl

LR4V chp

icp

X

FVe Mx sp5 DMSp5 5Sol

Pr

sol

SolDM SolM SolV SolIM 10N SolVL

12N Ro mlf

PCRt Sp5I

4V

MVe

SpVe

ECu

Li

IRt

ROb

Gi ts

AmbC

11n dsc/oc

rs

IODM GiV

PrBo vsc

C1 LPGi

RPa IOM

IOD py

ml bas

IOPr

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Cb 5th cerebellar lobule 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 7Cb 7th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 11n root of accessory nerve 12N hypoglossal nu AmbC ambiguus nu, compact part apmf ansoparamedian fissure bas basilar artery C1 C1 adrenaline cells cbw cerebellar white matter chp choroid plexus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule DMC dorsomed hy nu, compact DMSp5 dorsomed spinal trigem nu dsc/oc dors spino / olivocereb tr ECIC external cx inferior coll ECu external cuneate nu EGL external granular layer Cb Fl flocculus FVe F cell group vestib Gi gigantocellular reticular nu GiV gigantocellular retic, vent GrCb granule cell layer cb icf intercrural fissure icp inf cerebellar peduncle IntP interposed cerebellar nu, post IOD inf olive, dorsal nu IODM inf olive, dorsomed cell group IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu Li linear nu of the medulla LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle Med medial cerebellar nu MedDL medial Cb, dorsolat protub ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb MVe medial vestibular nu Mx matrix region medulla PCRt parvicell reticular nu PFl paraflocculus pfs parafloccular sulcus Pk Purkinje cell layer Cb plf posterolateral fissure PM paramedian lobule Pr prepositus nu PrBo pre-Botzinger complex psf post superior fissure py pyramidal tr Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract Sim simple lobule sol solitary tract SolDM nu sol tract, dorsomed SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu ts tectospinal tr vsc ventral spinocerebellar tr X nu X

Figure 167 P6 #64 9.03 mm

EGL

psf

6Cb

Crus1

Sim

Crus1 icf cbw

Crus2 7Cb apmf

MedDL PM

Med

IntP

9Cb MoCb

Pk PFl

pfs

GrCb ECu

LR4V CCrus

Mx DMSp5

chp sp5

TempP

Sp5I

SpVe sol SolL

MVe SolDL

12N Ro

IRt

PCRt

mlf

Li

ts Li RVRG

rs

IODM IOD

CVL LPGi C1

py Occ

RPa

IOM

S9Gn JugF

ROb

Gi

AmbSC

vsc

Z 4V Pr In

SolM SolIM 5Sol SolV 10N SolVL

dsc/oc

PFlCv

10Cb

bas ml

IOPr 12n 12C

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 7Cb 7th cerebellar lobule 9Cb 9th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12C hypoglossal canal 12N hypoglossal nu 12n root of hypoglossal nerve AmbSC ambiguus nu, subcompact apmf ansoparamedian fissure bas basilar artery C1 C1 adrenaline cells cbw cerebellar white matter CCrus common crus chp choroid plexus Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule CVL caudoventrolat reticular nu DMSp5 dorsomed spinal trigem nu dsc/oc dors spino / olivocereb tr ECu external cuneate nu EGL external granular layer Cb Gi gigantocellular reticular nu GrCb granule cell layer cb icf intercrural fissure In intercalated nu medulla IntP interposed cerebellar nu, post IOD inf olive, dorsal nu IODM inf olive, dorsomed cell group IOM inf olive, med nu IOPr inf olive, principal nu IRt intermed reticular nu JugF jugular foramen Li linear nu of the medulla LPGi lat paragigantocellular nu LR4V lat recess 4th ventricle Med medial cerebellar nu MedDL medial Cb, dorsolat protub ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb MVe medial vestibular nu Mx matrix region medulla Occ occipital bone PCRt parvicell reticular nu PFl paraflocculus PFlCv parafloccular cavity pfs parafloccular sulcus Pk Purkinje cell layer Cb PM paramedian lobule Pr prepositus nu psf post superior fissure py pyramidal tr Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract RVRG rost vent respiratory S9Gn superior ganglion 9n Sim simple lobule sol solitary tract SolDL sol nu, dorsolateral SolIM nu sol tract, intermediate SolL nu sol tract, lateral SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu TempP temporal bone, petrous ts tectospinal tr vsc ventral spinocerebellar tr Z nu Z

Figure 168 P6 #65 9.15mm

EGL psf

Crus1

6Cb Sim

Crus1 icf GrCb

7Cb

Pk

MoCb

Crus2 psf apmf cbw

PM

9Cb ppf Cop CCrus LR4V chp

Pa5 sp5

Pk

EGL SolDL SubP ECu SpVe MVe SolG AP Cu SolM 4V Mx SolCe DMSp5 5Sol SolVSolIM 10N PSol In SolVL 12N 10Cb

PCRt

Sp5I

IRt Li

dsc/oc

IOVL

12n

IOBe

LRt

rs RVRG C1

ROb

ts

AmbSC

Li

vsc

Gi

Ro mlf

IOD

LRtS5

IOM ml bas

py IOPr

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 7Cb 7th cerebellar lobule 9Cb 9th cerebellar lobule 10Cb 10th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu 12n root of hypoglossal nerve AmbSC ambiguus nu, subcompact AP area postrema apmf ansoparamedian fissure bas basilar artery C1 C1 adrenaline cells cbw cerebellar white matter CCrus common crus chp choroid plexus Cop copula pyramis Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule Cu cuneate nu DMSp5 dorsomed spinal trigem nu dsc/oc dors spino / olivocereb tr ECu external cuneate nu EGL external granular layer Cb Gi gigantocellular reticular nu GrCb granule cell layer cb icf intercrural fissure In intercalated nu medulla IOBe inf olive, beta subnu IOD inf olive, dorsal nu IOM inf olive, med nu IOPr inf olive, principal nu IOVL inf olive, ventrolateral IRt intermed reticular nu Li linear nu of the medulla LR4V lat recess 4th ventricle LRt lateral reticular nu LRtS5 lat reticular nu, subtrigeminal ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb MVe medial vestibular nu Mx matrix region medulla Pa5 paratrigeminal nu PCRt parvicell reticular nu Pk Purkinje cell layer Cb PM paramedian lobule ppf prepyramidal fissure psf post superior fissure PSol parasolitary nu py pyramidal tr Ro nu of Roller ROb raphe obscurus nu rs rubrospinal tract RVRG rost vent respiratory Sim simple lobule SolCe nu sol tract, central SolDL sol nu, dorsolateral SolG nu sol tract, gelatinous SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SpVe spinal vestibular nu SubP subpostrema area ts tectospinal tr vsc ventral spinocerebellar tr

Figure 169 P6 #66 9.27 mm

Crus1

psf

6Cb

Crus1 icf 7Cb MoCb GrCb

Crus2

cbw

Pk

EGL

8Cb sf

PM

cbw 9Cb SubP

ppf Cop

Gr

ECu sp5

Pa5

PSol Mx 5Sol SolVL

SolCe

SolM

SolV SolIM

10N

4V

12N

sp5 Sp5I

PCRt

rs dsc

LRt

Ro

IRt

AmbL

Gi LRt

RVRG C1/A1

LRtPC

12n

mlf

ROb ts

IOVL

IOBe IOD IOC IOB ml py bas

LRtS5 vsc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

AP

SolG

Cu

DMSp5

chp

SolDL

IOPr

0

0.2

0.4

0.6

0.8

1.0 mm

4V 4th ventricle 5Sol trigeminal-solitary trans 6Cb 6th cerebellar lobule 7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu 12n root of hypoglossal nerve AmbL ambiguus nu, loose part AP area postrema bas basilar artery C1/A1 adren/ noradrenaline cells cbw cerebellar white matter chp choroid plexus Cop copula pyramis Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule Cu cuneate nu DMSp5 dorsomed spinal trigem nu dsc dorsal spinocereb tract ECu external cuneate nu EGL external granular layer Cb Gi gigantocellular reticular nu Gr gracile nu GrCb granule cell layer cb icf intercrural fissure IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOD inf olive, dorsal nu IOPr inf olive, principal nu IOVL inf olive, ventrolateral IRt intermed reticular nu LRt lateral reticular nu LRtPC lat reticular nu, parvicellular LRtS5 lat reticular nu, subtrigeminal ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb Mx matrix region medulla Pa5 paratrigeminal nu PCRt parvicell reticular nu Pk Purkinje cell layer Cb PM paramedian lobule ppf prepyramidal fissure psf post superior fissure PSol parasolitary nu py pyramidal tr Ro nu of Roller ROb raphe obscurus nu rs rubrospinal tract RVRG rost vent respiratory sf secondary fissure SolCe nu sol tract, central SolDL sol nu, dorsolateral SolG nu sol tract, gelatinous SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SubP subpostrema area ts tectospinal tr vsc ventral spinocerebellar tr

Figure 170 P6 #67 9.39 mm

Crus1 icf

7Cb

Crus2

apmf EGL

PM

8Cb

Pk

GrCb

MoCb sf 9Cb

cbw ppf

Pk

sf Cop

SolDL

ECu

pms

Gr

SolG SolM PSol sol SolCe SolV

Cu Pa5

5Sol Mx

SolVL

sp5

10N

MdD 12GH mlf

IRt AmbL

dsc/oc PrLSp rs LRtS5 vsc

RVRG

IOVL

LRt

C1/A1

0

ts

MdV

IOPr 12n LRtPC

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

CC

SolIM

12N

Sp5I

11n

SubP AP

0.2

IOBe

IOD

IOC RPa IOB ml IOA py bas

0.4

0.6

0.8

1.0 mm

5Sol trigeminal-solitary trans 7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10N dorsal motor nu of vagus 11n root of accessory nerve 12GH hypoglossal nu, geniohyoid 12N hypoglossal nu 12n root of hypoglossal nerve AmbL ambiguus nu, loose part AP area postrema apmf ansoparamedian fissure bas basilar artery C1/A1 adren/ noradrenaline cells cbw cerebellar white matter CC central canal Cop copula pyramis Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule Cu cuneate nu dsc/oc dors spino / olivocereb tr ECu external cuneate nu EGL external granular layer Cb Gr gracile nu GrCb granule cell layer cb icf intercrural fissure IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOD inf olive, dorsal nu IOPr inf olive, principal nu IOVL inf olive, ventrolateral IRt intermed reticular nu LRt lateral reticular nu LRtPC lat reticular nu, parvicellular LRtS5 lat reticular nu, subtrigeminal MdD medullary reticular nu, dors MdV medullary reticular nu, vent ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb Mx matrix region medulla Pa5 paratrigeminal nu Pk Purkinje cell layer Cb PM paramedian lobule pms paramedian sulcus ppf prepyramidal fissure PrLSp pre lateral spinal PSol parasolitary nu py pyramidal tr RPa raphe pallidus nu rs rubrospinal tract RVRG rost vent respiratory sf secondary fissure sol solitary tract SolCe nu sol tract, central SolDL sol nu, dorsolateral SolG nu sol tract, gelatinous SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5I spinal trigem nu, interpolar SubP subpostrema area ts tectospinal tr vsc ventral spinocerebellar tr

Figure 171 P6 #68 9.51 mm

Crus1

icf

7Cb Crus2

MoCb Pk

apmf 8Cb GrCb

PM sf ppf

GrCb cbw Cop

9Cb

SolDL EGL PSol Gr Cu AP sol SolM CuR SolC SolV Mx 10N CC SolVL SolIM CeCv MdD 12N

pms sp5 Sp5C

IRt

mlf

Sp5I PrLSp

RVRG

IOD

LRt vsc

A1/C1 LRtPC

IOA

IOB py

IOC ml

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

ROb

ts

IOBe

rs dsc/oc LRtS5

MdV IOK

AmbL

0

0.2

0.4

0.6

0.8

RPa

bas

1.0 mm

7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu A1/C1 noradrenaline/adren cells AmbL ambiguus nu, loose part AP area postrema apmf ansoparamedian fissure bas basilar artery cbw cerebellar white matter CC central canal CeCv central cervical nu Cop copula pyramis Crus1 crus 1 ansiform lobule Crus2 crus 2 ansiform lobule Cu cuneate nu CuR cuneate nu, rotundus part dsc/oc dors spino / olivocereb tr EGL external granular layer Cb Gr gracile nu GrCb granule cell layer cb icf intercrural fissure IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOD inf olive, dorsal nu IOK inf olive, cap of Kooy med nu IRt intermed reticular nu LRt lateral reticular nu LRtPC lat reticular nu, parvicellular LRtS5 lat reticular nu, subtrigeminal MdD medullary reticular nu, dors MdV medullary reticular nu, vent ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb Mx matrix region medulla Pk Purkinje cell layer Cb PM paramedian lobule pms paramedian sulcus ppf prepyramidal fissure PrLSp pre lateral spinal PSol parasolitary nu py pyramidal tr ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract RVRG rost vent respiratory sf secondary fissure sol solitary tract SolC nu sol tract, comm part SolDL sol nu, dorsolateral SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar ts tectospinal tr vsc ventral spinocerebellar tr

Figure 172 P6 #69 9.63 mm

cbw 7Cb

Crus2 apmf PM

cbw 8Cb sf

ppf

EGL Pk

MoCb

GrCb

Cop

cbw pms

Gr

Cu

SolIM SolDL

CuR Mx

sp5

sol SolV

SolVL

Sp5C MdD

9Cb AP

10N

mlf MdV

RVRG

PrLSp dsc/oc

rs vsc

A1/C1 LRt

CC

CeCv 12N Ro

IRt RAmb

Sp5I

SubP

SolM SolC

ts 12n IOB IOA

LRtPC

ROb IOK IOBe

IOC RPa

py ml vert

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu 12n root of hypoglossal nerve A1/C1 noradrenaline/adren cells AP area postrema apmf ansoparamedian fissure cbw cerebellar white matter CC central canal CeCv central cervical nu Cop copula pyramis Crus2 crus 2 ansiform lobule Cu cuneate nu CuR cuneate nu, rotundus part dsc/oc dors spino / olivocereb tr EGL external granular layer Cb Gr gracile nu GrCb granule cell layer cb IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOK inf olive, cap of Kooy med nu IRt intermed reticular nu LRt lateral reticular nu LRtPC lat reticular nu, parvicellular MdD medullary reticular nu, dors MdV medullary reticular nu, vent ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb Mx matrix region medulla Pk Purkinje cell layer Cb PM paramedian lobule pms paramedian sulcus ppf prepyramidal fissure PrLSp pre lateral spinal py pyramidal tr RAmb retroambiguus nu Ro nu of Roller ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract RVRG rost vent respiratory sf secondary fissure sol solitary tract SolC nu sol tract, comm part SolDL sol nu, dorsolateral SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar SubP subpostrema area ts tectospinal tr vert vertebral art vsc ventral spinocerebellar tr

Figure 173 P6 #70 9.75 mm

7Cb

ppf

8Cb EGL

sf

MoCb

Cop

Pk

GrCb cbw

9Cb

cu sp5

Cu Gr SolDL CuR sol

Mx

Sp5C

RAmb

MdV mlf IOBe ts IOC

A1 LRt

vsc

10N

CC

CeCv 12N

IRt

Sp5I PrLSp rs dsc

SolC SolM

SolVL SolV SolIM

MdD

AP SubP

ml

IOB IOA

py

LRtPC

IOK ROb

RPa

vert

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10N dorsal motor nu of vagus 12N hypoglossal nu A1 A1 noradrenaline cells AP area postrema cbw cerebellar white matter CC central canal CeCv central cervical nu Cop copula pyramis Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part dsc dorsal spinocereb tract EGL external granular layer Cb Gr gracile nu GrCb granule cell layer cb IOA inf olive, subnu A medial nu IOB inf olive, subnu B med nu IOBe inf olive, beta subnu IOC inf olive, subnu C of med nu IOK inf olive, cap of Kooy med nu IRt intermed reticular nu LRt lateral reticular nu LRtPC lat reticular nu, parvicellular MdD medullary reticular nu, dors MdV medullary reticular nu, vent ml medial lemniscus mlf med longitudinal fasciculus MoCb molecular layer Cb Mx matrix region medulla Pk Purkinje cell layer Cb ppf prepyramidal fissure PrLSp pre lateral spinal py pyramidal tr RAmb retroambiguus nu ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract sf secondary fissure sol solitary tract SolC nu sol tract, comm part SolDL sol nu, dorsolateral SolIM nu sol tract, intermediate SolM nu sol tract, medial SolV sol nu, ventral part SolVL nu sol tract, ventrolateral sp5 spinal trigem tract Sp5C spinal trigem nu, caudal Sp5I spinal trigem nu, interpolar SubP subpostrema area ts tectospinal tr vert vertebral art vsc ventral spinocerebellar tr

Figure 174 P6 #71 9.87 mm

7Cb

ppf

8Cb sf Pk

EGL

MoCb

GrCb

sp5

Gr cu SolM SolIM Cu sol SolC Mx CuR SolL 10N CC SolV MdD CeCv 12N IRt

Sp5C

MdV

RAmb dsc

9Cb

mlf

ROb

11N

PrLSp rs A1

ts

11n LRt

IOA

vsc

py RPa

vert

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

7Cb 7th cerebellar lobule 8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 10N dorsal motor nu of vagus 11N accessory nerve nu 11n root of accessory nerve 12N hypoglossal nu A1 A1 noradrenaline cells CC central canal CeCv central cervical nu Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part dsc dorsal spinocereb tract EGL external granular layer Cb Gr gracile nu GrCb granule cell layer cb IOA inf olive, subnu A medial nu IRt intermed reticular nu LRt lateral reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent mlf med longitudinal fasciculus MoCb molecular layer Cb Mx matrix region medulla Pk Purkinje cell layer Cb ppf prepyramidal fissure PrLSp pre lateral spinal py pyramidal tr RAmb retroambiguus nu ROb raphe obscurus nu RPa raphe pallidus nu rs rubrospinal tract sf secondary fissure sol solitary tract SolC nu sol tract, comm part SolIM nu sol tract, intermediate SolL nu sol tract, lateral SolM nu sol tract, medial SolV sol nu, ventral part sp5 spinal trigem tract Sp5C spinal trigem nu, caudal ts tectospinal tr vert vertebral art vsc ventral spinocerebellar tr

Figure 175 P6 #72 9.99 mm

8Cb sf MoCb

EGL Pk

GrCb

Gr gr cu Cu MnA CuR Mx IB SolM SolC CC MdD CeCv 12N IRt mlx

sp5 Ge5 Sp5C

PrLSp

dsc

9Cb

rs A1

MdV RAmb 11N

mlf ts py

vsc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

0.4

0.6

0.8

1.0 mm

8Cb 8th cerebellar lobule 9Cb 9th cerebellar lobule 11N accessory nerve nu 12N hypoglossal nu A1 A1 noradrenaline cells CC central canal CeCv central cervical nu Cu cuneate nu cu cuneate fasciculus CuR cuneate nu, rotundus part dsc dorsal spinocereb tract EGL external granular layer Cb Ge5 gelatinous layer caudal Sp5 Gr gracile nu gr gracile fasciculus GrCb granule cell layer cb IB interstitial nu medulla IRt intermed reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent mlf med longitudinal fasciculus mlx med lemniscus decussation MnA median access nu medulla MoCb molecular layer Cb Mx matrix region medulla Pk Purkinje cell layer Cb PrLSp pre lateral spinal py pyramidal tr RAmb retroambiguus nu rs rubrospinal tract sf secondary fissure SolC nu sol tract, comm part SolM nu sol tract, medial sp5 spinal trigem tract Sp5C spinal trigem nu, caudal ts tectospinal tr vsc ventral spinocerebellar tr

Figure 176 P6 #73 10.11 mm

EGL Pk 9Cb MoCb GrCb cu gr Gr MnA Cu Mx IB SolC SolM

sp5 Sp5C MdD

CC

ia

CeCv

IRt dsc

MdV mlf rs

A1

11N

ts py

vsc

Atlas of the Developing Mouse Brain Paxinos Halliday Watson Koutcherov Wang

0

0.2

pyx

0.4

0.6

0.8

1.0 mm

9Cb 9th cerebellar lobule 11N accessory nerve nu A1 A1 noradrenaline cells CC central canal CeCv central cervical nu Cu cuneate nu cu cuneate fasciculus dsc dorsal spinocereb tract EGL external granular layer Cb Gr gracile nu gr gracile fasciculus GrCb granule cell layer cb ia internal arcuate fibers IB interstitial nu medulla IRt intermed reticular nu MdD medullary reticular nu, dors MdV medullary reticular nu, vent mlf med longitudinal fasciculus MnA median access nu medulla MoCb molecular layer Cb Mx matrix region medulla Pk Purkinje cell layer Cb py pyramidal tr pyx pyramidal decussation rs rubrospinal tract SolC nu sol tract, comm part SolM nu sol tract, medial sp5 spinal trigem tract Sp5C spinal trigem nu, caudal ts tectospinal tr vsc ventral spinocerebellar tr